The mechanisms and functions of IL-1β in intervertebral disc degeneration
Published 2023 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
The mechanisms and functions of IL-1β in intervertebral disc degeneration
Authors
Keywords
-
Journal
EXPERIMENTAL GERONTOLOGY
Volume 177, Issue -, Pages 112181
Publisher
Elsevier BV
Online
2023-04-25
DOI
10.1016/j.exger.2023.112181
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Cyanidin attenuates the apoptosis of rat nucleus pulposus cells and the degeneration of intervertebral disc via the JAK2/STAT3 signal pathway in vitro and in vivo
- (2022) Xiaoliang Bai et al. PHARMACEUTICAL BIOLOGY
- Proanthocyanidins inhibit the apoptosis and aging of nucleus pulposus cells through the PI3K/Akt pathway delaying intervertebral disc degeneration
- (2022) Hai-Wei Chen et al. CONNECTIVE TISSUE RESEARCH
- SIRT1 alleviates IL-1β induced nucleus pulposus cells pyroptosis via mitophagy in intervertebral disc degeneration
- (2022) Zhaoxin Ma et al. INTERNATIONAL IMMUNOPHARMACOLOGY
- Anisodamine Maintains the Stability of Intervertebral Disc Tissue by Inhibiting the Senescence of Nucleus Pulposus Cells and Degradation of Extracellular Matrix via Interleukin-6/Janus Kinases/Signal Transducer and Activator of Transcription 3 Pathway
- (2021) Ning Tang et al. Frontiers in Pharmacology
- Roles of NLRP3 inflammasome in intervertebral disc degeneration
- (2021) G. Chao-yang et al. OSTEOARTHRITIS AND CARTILAGE
- Higenamine mitigates interleukin-1β-induced human nucleus pulposus cell apoptosis by ROS-mediated PI3K/Akt signaling
- (2021) Xiaojuan Zhu et al. MOLECULAR AND CELLULAR BIOCHEMISTRY
- Targeting oxidative stress in disease: promise and limitations of antioxidant therapy
- (2021) Henry Jay Forman et al. NATURE REVIEWS DRUG DISCOVERY
- MiR-144-3p induced by SP1 promotes IL-1β-induced pyroptosis in chondrocytes via PTEN/PINK1/Parkin axis
- (2021) Jin-Mei Jiang et al. AUTOIMMUNITY
- Ganoderic Acid A Attenuates IL-1β-Induced Inflammation in Human Nucleus Pulposus Cells Through Inhibiting the NF-κB Pathway
- (2021) Sihua Zheng et al. INFLAMMATION
- The protective effects of etomidate against interleukin-1β (IL-1β)-induced oxidative stress, extracellular matrix alteration and cellular senescence in chondrocytes
- (2021) Miaomiao Yin et al. Bioengineered
- Nicotinamide Phosphoribosyl Transferase Controls NLRP3 Inflammasome Activity Through MAPK and NF-κB Signaling in Nucleus Pulposus Cells, as Suppressed by Melatonin
- (2020) Yingjie Huang et al. INFLAMMATION
- Inflammatory cytokine and catabolic enzyme expression in a goat model of intervertebral disc degeneration
- (2020) Chenghao Zhang et al. JOURNAL OF ORTHOPAEDIC RESEARCH
- Propionibacterium acnes induces intervertebral disc degeneration by promoting nucleus pulposus cell pyroptosis via NLRP3-dependent pathway
- (2020) Danshuang He et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Bmi deficiency causes oxidative stress and intervertebral disc degeneration which can be alleviated by antioxidant treatment
- (2020) Qunhu Zhang et al. JOURNAL OF CELLULAR AND MOLECULAR MEDICINE
- Severity of intervertebral disc herniation regulates cytokine and chemokine levels in patients with chronic radicular back pain
- (2020) H.E. Jacobsen et al. OSTEOARTHRITIS AND CARTILAGE
- Resveratrol inhibits IL-1β-mediated nucleus pulposus cell apoptosis through regulating the PI3K/Akt pathway
- (2019) Yanhai Jiang et al. BIOSCIENCE REPORTS
- 1,4-Dihydropyridine (DHP) suppresses against oxidative stress in nucleus pulposus via activating sirtuin-1
- (2019) Yuxin Song et al. BIOMEDICINE & PHARMACOTHERAPY
- IL-10 delays the degeneration of intervertebral discs by suppressing the p38 MAPK signaling pathway
- (2019) Jun Ge et al. FREE RADICAL BIOLOGY AND MEDICINE
- Naringin Protects Against Interleukin 1β (IL-1β)-Induced Human Nucleus Pulposus Cells Degeneration via Downregulation Nuclear Factor kappa B (NF-κB) Pathway and p53 Expression
- (2019) Gang Gao et al. MEDICAL SCIENCE MONITOR
- Interleukin-1β induces apoptosis in annulus fibrosus cells through the extracellular signal-regulated kinase pathway
- (2018) Xing Yang et al. CONNECTIVE TISSUE RESEARCH
- Honokiol alleviates the degeneration of intervertebral disc via suppressing the activation of TXNIP-NLRP3 inflammasome signal pathway
- (2018) Pan Tang et al. FREE RADICAL BIOLOGY AND MEDICINE
- Nerves and blood vessels in degenerated intervertebral discs are confined to physically disrupted tissue
- (2018) Polly Lama et al. JOURNAL OF ANATOMY
- Wogonin mitigates intervertebral disc degeneration through the Nrf2/ARE and MAPK signaling pathways
- (2018) Weijing Fang et al. INTERNATIONAL IMMUNOPHARMACOLOGY
- The Role of Hypoxia in Angiogenesis and Extracellular Matrix Regulation of Intervertebral Disc Cells During Inflammatory Reactions
- (2017) Woo-Keun Kwon et al. NEUROSURGERY
- ROS: Crucial Intermediators in the Pathogenesis of Intervertebral Disc Degeneration
- (2017) Chencheng Feng et al. Oxidative Medicine and Cellular Longevity
- Inflammatory Processes Associated with Canine Intervertebral Disc Herniation
- (2017) Marie Monchaux et al. Frontiers in Immunology
- Disc cell senescence in intervertebral disc degeneration: Causes and molecular pathways
- (2016) Chencheng Feng et al. CELL CYCLE
- Pyroptosis
- (2016) Lieselotte Vande Walle et al. CURRENT BIOLOGY
- Mechanisms and regulation of endothelial VEGF receptor signalling
- (2016) Michael Simons et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- PGE1 Attenuates IL-1β-induced NGF Expression in Human Intervertebral Disc Cells
- (2016) Kazuma Murata et al. SPINE
- Beta1 integrin inhibits apoptosis induced by cyclic stretch in annulus fibrosus cells via ERK1/2 MAPK pathway
- (2015) Kai Zhang et al. APOPTOSIS
- Calcium and mitochondria in the regulation of cell death
- (2015) Sten Orrenius et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Hyaluronic Acid Based Hydrogels Attenuate Inflammatory Receptors and Neurotrophins in Interleukin-1β Induced Inflammation Model of Nucleus Pulposus Cells
- (2015) Isma Liza Mohd Isa et al. BIOMACROMOLECULES
- Duration-dependent influence of dynamic torsion on the intervertebral disc: an intact disc organ culture study
- (2015) Samantha C. W. Chan et al. EUROPEAN SPINE JOURNAL
- Proinflammatory cytokines modulate the chemokine CCL2 (MCP-1) in human annulus cells in vitro: CCL2 expression and production
- (2015) Helen E. Gruber et al. EXPERIMENTAL AND MOLECULAR PATHOLOGY
- Inflammation in intervertebral disc degeneration and regeneration
- (2015) M. Molinos et al. Journal of the Royal Society Interface
- Potential roles of cytokines and chemokines in human intervertebral disc degeneration: interleukin-1 is a master regulator of catabolic processes
- (2015) K.L.E. Phillips et al. OSTEOARTHRITIS AND CARTILAGE
- Expression of Matrix Metalloproteinases is Positively Related to the Severity of Disc Degeneration and Growing Age in the East Asian Lumbar Disc Herniation Patients
- (2014) Haidong Xu et al. CELL BIOCHEMISTRY AND BIOPHYSICS
- Production and expression of RANTES (CCL5) by human disc cells and modulation by IL-1-β and TNF-α in 3D culture
- (2014) Helen E. Gruber et al. EXPERIMENTAL AND MOLECULAR PATHOLOGY
- Protective effects of ginsenoside Rg3 on human osteoarthritic chondrocytes
- (2014) Min Wook So et al. Modern Rheumatology
- Different concentrations of 17β-estradiol modulates apoptosis induced by interleukin-1β in rat annulus fibrosus cells
- (2014) HAIYING WANG et al. Molecular Medicine Reports
- Extracellular matrix assembly: a multiscale deconstruction
- (2014) Janna K. Mouw et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- ISSLS Prize Winner
- (2014) Masayuki Miyagi et al. SPINE
- Microbial modulation of host apoptosis and pyroptosis
- (2014) Yongqun He et al. Frontiers in Cellular and Infection Microbiology
- Cell death in intervertebral disc degeneration
- (2013) Fan Ding et al. APOPTOSIS
- Increased IL-17 expression in degenerated human discs and increased production in cultured annulus cells exposed to IL-1ß and TNF-α
- (2013) HE Gruber et al. BIOTECHNIC & HISTOCHEMISTRY
- Mitochondrial-derived reactive oxygen species (ROS) play a causal role in aging-related intervertebral disc degeneration
- (2013) Luigi A. Nasto et al. JOURNAL OF ORTHOPAEDIC RESEARCH
- Role of cytokines in intervertebral disc degeneration: pain and disc content
- (2013) Makarand V. Risbud et al. Nature Reviews Rheumatology
- Effects of secreted factors in culture medium of annulus fibrosus cells on microvascular endothelial cells: elucidating the possible pathomechanisms of matrix degradation and nerve in-growth in disc degeneration
- (2013) H.J. Moon et al. OSTEOARTHRITIS AND CARTILAGE
- Extracellular Signal-Regulated Kinase Inhibition Modulates Rat Annulus Fibrosus Cell Response to Interleukin-1
- (2013) Yuan Wei et al. SPINE
- Effect of Biphasic Electrical Current Stimulation on IL-1β–Stimulated Annulus Fibrosus Cells Using In Vitro Microcurrent Generating Chamber System
- (2013) Joo Han Kim et al. SPINE
- Expression and regulation of metalloproteinases and their inhibitors in intervertebral disc aging and degeneration
- (2013) Nam V. Vo et al. Spine Journal
- Enhancing intervertebral disc repair and regeneration through biology: platelet-rich plasma as an alternative strategy
- (2013) Shan-Zheng Wang et al. ARTHRITIS RESEARCH & THERAPY
- Tumor necrosis factor α- and interleukin-1β-dependent induction of CCL3 expression by nucleus pulposus cells promotes macrophage migration through CCR1
- (2012) Jianru Wang et al. ARTHRITIS AND RHEUMATISM
- Interleukin 1-beta upregulates brain-derived neurotrophic factor, neurotrophin 3 and neuropilin 2 gene expression and NGF production in annulus cells
- (2012) HE Gruber et al. BIOTECHNIC & HISTOCHEMISTRY
- Effects of IGF-1 on IL-1β-induced apoptosis in rabbit nucleus pulposus cells in vitro
- (2012) CHANG-CHUN ZHANG et al. Molecular Medicine Reports
- Interleukin-1 in the pathogenesis and treatment of inflammatory diseases
- (2011) C. A. Dinarello BLOOD
- The Red Wine Polyphenol Resveratrol Shows Promising Potential for the Treatment of Nucleus Pulposus–Mediated Pain In Vitro and In Vivo
- (2011) Karin Wuertz et al. SPINE
- ADAMTS-5 and Intervertebral Disc Degeneration: The Results of Tissue Immunohistochemistry and In Vitro Cell Culture
- (2010) Chang-Qing Zhao et al. JOURNAL OF ORTHOPAEDIC RESEARCH
- Interleukin-1β induces angiogenesis and innervation in human intervertebral disc degeneration
- (2010) Jae Man Lee et al. JOURNAL OF ORTHOPAEDIC RESEARCH
- Frequency of Lumbar Intervertebral Disc Calcification and Angiogenesis, and Their Correlation With Clinical, Surgical, and Magnetic Resonance Imaging Findings
- (2010) Saeid Karamouzian et al. SPINE
- Immunological and Inflammatory Functions of the Interleukin-1 Family
- (2009) Charles A. Dinarello Annual Review of Immunology
- Influence of cytokine inhibitors on concentration and activity of MMP-1 and MMP-3 in disc herniation
- (2009) Stéphane Genevay et al. ARTHRITIS RESEARCH & THERAPY
- Regulation of catabolic gene expression in normal and degenerate human intervertebral disc cells: implications for the pathogenesis of intervertebral disc degeneration
- (2009) S Jane Millward-Sadler et al. ARTHRITIS RESEARCH & THERAPY
- Inhibition of interleukin-1β-induced matrix metalloproteinases 1 and 13 production in human osteoarthritic chondrocytes by prostaglandin D2
- (2008) Nadia Zayed et al. ARTHRITIS AND RHEUMATISM
- Intervertebral disc cell response to dynamic compression is age and frequency dependent
- (2008) Casey L. Korecki et al. JOURNAL OF ORTHOPAEDIC RESEARCH
- Expression and regulation of neurotrophins in the nondegenerate and degenerate human intervertebral disc
- (2008) Devina Purmessur et al. ARTHRITIS RESEARCH & THERAPY
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExploreAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started