Targeting Endogenous Reactive Oxygen Species Removal and Regulating Regenerative Microenvironment at Annulus Fibrosus Defects Promote Tissue Repair

Prussian Blue Nanoparticles Stabilize SOD1 from Ubiquitination‐Proteasome Degradation to Rescue Intervertebral Disc Degeneration

(2022) Tangjun Zhou et al.   Advanced Science

Biomaterials for recruiting and activating endogenous stem cells in situ tissue regeneration

(2022) Ingrid Safina et al.   Acta Biomaterialia

Therapeutic Hydrogel Patch to Treat Atopic Dermatitis by Regulating Oxidative Stress

(2022) Ye Eun Kim et al.   NANO LETTERS

ZnO nanoparticles attenuate polymer-wear-particle induced inflammatory osteolysis by regulating the MEK-ERK-COX-2 axis

(2022) Xiangchao Meng et al.   Journal of Orthopaedic Translation

Ceria nanoparticles prophylactic used for renal ischemia-reperfusion injury treatment by attenuating oxidative stress and inflammatory response

(2022) Lan Zhou et al.   BIOMATERIALS

Catalytic activity tunable ceria nanoparticles prevent chemotherapy-induced acute kidney injury without interference with chemotherapeutics

(2021) Qinjie Weng et al.   Nature Communications

Nanofibrous hyaluronic acid scaffolds delivering TGF-β3 and SDF-1α for articular cartilage repair in a large animal model

(2021) Anthony R. Martin et al.   Acta Biomaterialia

Ceria Nanozyme-Integrated Microneedles Reshape the Perifollicular Microenvironment for Androgenetic Alopecia Treatment

(2021) Anran Yuan et al.   ACS Nano

Bioactive in situ crosslinkable polymer-peptide hydrogel for cell delivery to the intervertebral disc in a rat model

(2021) Marcos N. Barcellona et al.   Acta Biomaterialia

Low Back Pain

(2021) Roger Chou   ANNALS OF INTERNAL MEDICINE

Hybrid Methacrylated Gelatin and Hyaluronic Acid Hydrogel Scaffolds. Preparation and Systematic Characterization for Prospective Tissue Engineering Applications

(2021) B. Velasco-Rodriguez et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Low back pain

(2021) Nebojsa Nick Knezevic et al.   LANCET

Natural Melanin/Alginate Hydrogels Achieve Cardiac Repair through ROS Scavenging and Macrophage Polarization

(2021) Jin Zhou et al.   Advanced Science

Self‐Healing Hydrogel Embodied with Macrophage‐Regulation and Responsive‐Gene‐Silencing Properties for Synergistic Prevention of Peritendinous Adhesion

(2021) Chuandong Cai et al.   ADVANCED MATERIALS

Surface Decoration of Redox-Modulating Nanoceria on 3D-Printed Tissue Scaffolds Promotes Stem Cell Osteogenesis and Attenuates Bacterial Colonization

(2021) Sagar Nilawar et al.   BIOMACROMOLECULES

Alleviating Oxidative Injury of Myocardial Infarction by a Fibrous Polyurethane Patch with Condensed ROS‐Scavenging Backbone Units

(2021) Jieqi Xie et al.   Advanced Healthcare Materials

Resveratrol Suppresses Annulus Fibrosus Cell Apoptosis through Regulating Oxidative Stress Reaction in an Inflammatory Environment

(2021) Qunqun Shan et al.   Biomed Research International

Injectable Self-Healing Ceria-based Nanocomposite Hydrogel with ROS-scavenging Activity for Skin Wound Repair

(2021) Xueyun Gong et al.   Regenerative Biomaterials

Bisphosphonate-based hydrogel mediates biomimetic negative feedback regulation of osteoclastic activity to promote bone regeneration

(2021) Zhuo Li et al.   Bioactive Materials

Programmed Sustained Release of Recombinant Human Bone Morphogenetic Protein-2 and Inorganic Ion Composite Hydrogel as Artificial Periosteum

(2020) Tianwen Xin et al.   ACS Applied Materials & Interfaces

p16 deficiency attenuates intervertebral disc degeneration by adjusting oxidative stress and nucleus pulposus cell cycle

(2020) Hui Che et al.   eLife

Regulation of differentiation of annulus fibrosus-derived stem cells using heterogeneous electrospun fibrous scaffolds

(2020) Pinghui Zhou et al.   Journal of Orthopaedic Translation

Oxidative Species-Selective Materials for Diagnostic and Therapeutic Applications

(2020) Caiyan Zhao et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Combined nucleus pulposus augmentation and annulus fibrosus repair prevents acute intervertebral disc degeneration after discectomy

(2020) Stephen R. Sloan et al.   Science Translational Medicine

Development of a two-part biomaterial adhesive strategy for annulus fibrosus repair and ex vivo evaluation of implant herniation risk

(2020) Tyler J. DiStefano B.E. et al.   BIOMATERIALS

One strike loading organ culture model to investigate the post-traumatic disc degenerative condition

(2020) Zhiyu Zhou et al.   Journal of Orthopaedic Translation

A versatile nanocomposite based on nanoceria for antibacterial enhancement and protection from aPDT-aggravated inflammation via modulation of macrophage polarization

(2020) Yue Sun et al.   BIOMATERIALS

Chondrocyte ferroptosis contribute to the progression of osteoarthritis

(2020) Xudong Yao et al.   Journal of Orthopaedic Translation

Synergistic Oxygen Generation and Reactive Oxygen Species Scavenging by Manganese Ferrite/Ceria Co-decorated Nanoparticles for Rheumatoid Arthritis Treatment

(2019) Jonghoon Kim et al.   ACS Nano

Reactive Oxygen Species (ROS)-Based Nanomedicine

(2019) Bowen Yang et al.   CHEMICAL REVIEWS

In vitro and in vivo evaluation of an electrospun-aligned microfibrous implant for Annulus fibrosus repair

(2019) Maude Gluais et al.   BIOMATERIALS

Synthesis and biomedical applications of nanoceria, a redox active nanoparticle

(2019) Neelam Thakur et al.   JOURNAL OF NANOBIOTECHNOLOGY

Ceria Nanoparticles Meet Hepatic Ischemia‐Reperfusion Injury: The Perfect Imperfection

(2019) Dalong Ni et al.   ADVANCED MATERIALS

Antioxidative nanomaterials and biomedical applications

(2019) Yanlan Liu et al.   Nano Today

Hydrogel microparticles for biomedical applications

(2019) Andrew C. Daly et al.   Nature Reviews Materials

Aberrant mechanosensing in injured intervertebral discs as a result of boundary-constraint disruption and residual-strain loss

(2019) Edward D. Bonnevie et al.   Nature Biomedical Engineering

In Vivo Annular Repair using High-Density Collagen Gel Seeded with Annulus Fibrosus Cells

(2018) Yu Moriguchi et al.   Acta Biomaterialia

Cartilage tissue formation through assembly of microgels containing mesenchymal stem cells

(2018) Fanyi Li et al.   Acta Biomaterialia

Custom-Made Ceria Nanoparticles Show a Neuroprotective Effect by Modulating Phenotypic Polarization of the Microglia

(2018) Feng Zeng et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Ceria Nanoparticle Systems for Selective Scavenging of Mitochondrial, Intracellular, and Extracellular Reactive Oxygen Species in Parkinson's Disease

(2018) Hyek Jin Kwon et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Ceria nanocrystals decorated mesoporous silica nanoparticle based ROS-scavenging tissue adhesive for highly efficient regenerative wound healing

(2018) Haibin Wu et al.   BIOMATERIALS

The tango of ROS and p53 in tissue stem cells

(2018) Youguo Chen et al.   CELL DEATH AND DIFFERENTIATION

Ethical and Safety Issues of Stem Cell-Based Therapy

(2018) Vladislav Volarevic et al.   International Journal of Medical Sciences

ROS signalling in the biology of cancer

(2018) Jennifer N. Moloney et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Hallmarks of Cellular Senescence

(2018) Alejandra Hernandez-Segura et al.   TRENDS IN CELL BIOLOGY

Targeted Therapy of Atherosclerosis by a Broad-Spectrum Reactive Oxygen Species Scavenging Nanoparticle with Intrinsic Anti-inflammatory Activity

(2018) Yuquan Wang et al.   ACS Nano

Materials Science and Design Principles of Growth Factor Delivery Systems in Tissue Engineering and Regenerative Medicine

(2018) Ramesh Subbiah et al.   Advanced Healthcare Materials

H2O2-responsive liposomal nanoprobe for photoacoustic inflammation imaging and tumor theranostics via in vivo chromogenic assay

(2017) Qian Chen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

TGFβ3 recruits endogenous mesenchymal stem cells to initiate bone regeneration

(2017) Moyuan Deng et al.   Stem Cell Research & Therapy

Valence State Manipulation of Cerium Oxide Nanoparticles on a Titanium Surface for Modulating Cell Fate and Bone Formation

(2017) Jinhua Li et al.   Advanced Science

Functional Recovery of Contused Spinal Cord in Rat with the Injection of Optimal-Dosed Cerium Oxide Nanoparticles

(2017) Jong-Wan Kim et al.   Advanced Science

Mitochondria-Targeting Ceria Nanoparticles as Antioxidants for Alzheimer’s Disease

(2016) Hyek Jin Kwon et al.   ACS Nano

Mechanisms of lamellar collagen formation in connective tissues

(2016) Samaneh Ghazanfari et al.   BIOMATERIALS

Nanoceria restrains PM2.5-induced metabolic disorder and hypothalamus inflammation by inhibition of astrocytes activation related NF-κB pathway in Nrf2 deficient mice

(2016) Min-Xuan Xu et al.   FREE RADICAL BIOLOGY AND MEDICINE

Injectable Hydrogels with In Situ Double Network Formation Enhance Retention of Transplanted Stem Cells

(2015) Lei Cai et al.   ADVANCED FUNCTIONAL MATERIALS

Microfluidic-Based Generation of Size-Controlled, Biofunctionalized Synthetic Polymer Microgels for Cell Encapsulation

(2014) Devon M. Headen et al.   ADVANCED MATERIALS

Cerium oxide nanoparticles accelerate the decay of peroxynitrite (ONOO−)

(2013) Janet M. Dowding et al.   Drug Delivery and Translational Research

Ceria Nanoparticles that can Protect against Ischemic Stroke

(2012) Chi Kyung Kim et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Nuclear-Targeted Drug Delivery of TAT Peptide-Conjugated Monodisperse Mesoporous Silica Nanoparticles

(2012) Limin Pan et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Anti-oxidants for therapeutic use: Why are only a few drugs in clinical use?

(2009) Keiichiro Suzuki   ADVANCED DRUG DELIVERY REVIEWS