Aberrant mechanosensing in injured intervertebral discs as a result of boundary-constraint disruption and residual-strain loss

Local nascent protein deposition and remodelling guide mesenchymal stromal cell mechanosensing and fate in three-dimensional hydrogels

(2019) Claudia Loebel et al.   NATURE MATERIALS

Mediating human stem cell behaviour via defined fibrous architectures by melt electrospinning writing

(2018) Kian F. Eichholz et al.   Acta Biomaterialia

Physiology and Engineering of the Graded Interfaces of Musculoskeletal Junctions

(2018) Edward D. Bonnevie et al.   Annual Review of Biomedical Engineering

FAK- and YAP/TAZ dependent mechanotransduction pathways are required for enhanced immunomodulatory properties of adipose-derived mesenchymal stem cells induced by aligned fibrous scaffolds

(2018) S. Wan et al.   BIOMATERIALS

Do mechanical strain and TNF-α interact to amplify pro-inflammatory cytokine production in human annulus fibrosus cells?

(2016) Morakot Likhitpanichkul et al.   JOURNAL OF BIOMECHANICS

MicroRNA-21 preserves the fibrotic mechanical memory of mesenchymal stem cells

(2016) Chen Xi Li et al.   NATURE MATERIALS

N-cadherin adhesive interactions modulate matrix mechanosensing and fate commitment of mesenchymal stem cells

(2016) Brian D. Cosgrove et al.   NATURE MATERIALS

Microstructural heterogeneity directs micromechanics and mechanobiology in native and engineered fibrocartilage

(2016) Woojin M. Han et al.   NATURE MATERIALS

NF- B Signaling Pathway in Controlling Intervertebral Disk Cell Response to Inflammatory and Mechanical Stressors

(2016) R. Tisherman et al.   PHYSICAL THERAPY

High fidelity visualization of cell-to-cell variation and temporal dynamics in nascent extracellular matrix formation

(2016) Claire M. McLeod et al.   Scientific Reports

Cytoskeletal to Nuclear Strain Transfer Regulates YAP Signaling in Mesenchymal Stem Cells

(2015) Tristan P. Driscoll et al.   BIOPHYSICAL JOURNAL

Injectable, high-density collagen gels for annulus fibrosus repair: Anin vitrorat tail model

(2014) Brandon Borde et al.   JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A

Needle puncture injury causes acute and long-term mechanical deficiency in a mouse model of intervertebral disc degeneration

(2013) John T. Martin et al.   JOURNAL OF ORTHOPAEDIC RESEARCH

The Mechanical Environment Modulates Intracellular Calcium Oscillation Activities of Myofibroblasts

(2013) Charles Godbout et al.   PLoS One

Force Fluctuations within Focal Adhesions Mediate ECM-Rigidity Sensing to Guide Directed Cell Migration

(2012) Sergey V. Plotnikov et al.   CELL

Large residual strains are present in the intervertebral disc annulus fibrosus in the unloaded state

(2012) A.J. Michalek et al.   JOURNAL OF BIOMECHANICS

Re-establishment of cytoskeletal tensional homeostasis in lax tendons occurs through an actin-mediated cellular contraction of the extracellular matrix

(2012) Keri Gardner et al.   JOURNAL OF ORTHOPAEDIC RESEARCH

Conversion of Mechanical Force into TGF-β-Mediated Biochemical Signals

(2011) Toru Maeda et al.   CURRENT BIOLOGY

Role of YAP/TAZ in mechanotransduction

(2011) Sirio Dupont et al.   NATURE

Wound Contraction Is Attenuated by Fasudil Inhibition of Rho-Associated Kinase

(2011) Jennifer E. Bond et al.   PLASTIC AND RECONSTRUCTIVE SURGERY

Quantitative analysis of collagen fiber organization in injured tendons using Fourier transform-second harmonic generation imaging

(2010) Mayandi Sivaguru et al.   OPTICS EXPRESS

Enhancing annulus fibrosus tissue formation in porous silk scaffolds

(2009) Godfrey Chang et al.   JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A

Non-Smad pathways in TGF-β signaling

(2008) Ying E Zhang   CELL RESEARCH

Loss of Homeostatic Tension Induces Apoptosis in Tendon Cells: An In Vitro Study

(2008) Monika Egerbacher et al.   CLINICAL ORTHOPAEDICS AND RELATED RESEARCH

Loss of Homeostatic Strain Alters Mechanostat “Set Point” of Tendon Cells In Vitro

(2008) Steven P. Arnoczky et al.   CLINICAL ORTHOPAEDICS AND RELATED RESEARCH