Bioactive in situ crosslinkable polymer-peptide hydrogel for cell delivery to the intervertebral disc in a rat model

Characterization of Biomaterials Intended for Use in the Nucleus Pulposus of Degenerated Intervertebral Discs

(2020) Tara C. Schmitz et al.   Acta Biomaterialia

Control of adhesive ligand density for modulation of nucleus pulposus cell phenotype

(2020) Marcos N. Barcellona et al.   BIOMATERIALS

Adipose stem cells exhibit mechanical memory and reduce fibrotic contracture in a rat elbow injury model

(2020) Chelsey Dunham et al.   FASEB JOURNAL

Intervertebral disc regeneration with an adipose mesenchymal stem cell-derived tissue-engineered construct in a rat nucleotomy model

(2019) Hiroyuki Ishiguro et al.   Acta Biomaterialia

Aging of mouse intervertebral disc and association with back pain

(2019) Kathleen Vincent et al.   BONE

Injectable Hydrogel Combined with Nucleus Pulposus-Derived Mesenchymal Stem Cells for the Treatment of Degenerative Intervertebral Disc in Rats

(2019) Feng Wang et al.   Stem Cells International

Mechanosensitive transcriptional coactivators MRTF-A and YAP/TAZ regulate nucleus pulposus cell phenotype through cell shape

(2019) Bailey V. Fearing et al.   FASEB JOURNAL

Large Cytoplasmic Vacuoles within Notochordal Nucleus Pulposus Cells: A Possible Regulator of Intracellular Pressure That Shapes the Cytoskeleton and Controls Proliferation

(2018) Xin Hong et al.   CELLS TISSUES ORGANS

The vacuolated morphology of chordoma cells is dependent on cytokeratin intermediate filaments

(2018) Lauren Resutek et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Long-term mechanical function and integration of an implanted tissue-engineered intervertebral disc

(2018) Sarah E. Gullbrand et al.   Science Translational Medicine

An acellular bioresorbable ultra-purified alginate gel promotes intervertebral disc repair: A preclinical proof-of-concept study

(2018) Takeru Tsujimoto et al.   EBioMedicine

MR Elastography–derived Stiffness: A Biomarker for Intervertebral Disc Degeneration

(2017) Benjamin A. Walter et al.   RADIOLOGY

Formation, function, and exhaustion of notochordal cytoplasmic vacuoles within intervertebral disc: current understanding and speculation

(2017) Feng Wang et al.   Oncotarget

Peptide:glycosaminoglycan hybrid hydrogels as an injectable intervention for spinal disc degeneration

(2016) D. E. Miles et al.   Journal of Materials Chemistry B

Synthetic matrices reveal contributions of ECM biophysical and biochemical properties to epithelial morphogenesis

(2015) Nduka O. Enemchukwu et al.   JOURNAL OF CELL BIOLOGY

Defining the phenotype of young healthy nucleus pulposus cells: Recommendations of the Spine Research Interest Group at the 2014 annual ORS meeting

(2015) Makarand V. Risbud et al.   JOURNAL OF ORTHOPAEDIC RESEARCH

N-Cadherin-Mediated Signaling Regulates Cell Phenotype for Nucleus Pulposus Cells of the Intervertebral Disc

(2014) Priscilla Y. Hwang et al.   Cellular and Molecular Bioengineering

A comparison of intravenous and intradiscal delivery of multipotential stem cells on the healing of injured intervertebral disk

(2014) Vivian Tam et al.   JOURNAL OF ORTHOPAEDIC RESEARCH

In Vitro Characterization of a Stem-Cell-Seeded Triple-Interpenetrating-Network Hydrogel for Functional Regeneration of the Nucleus Pulposus

(2014) Lachlan J. Smith et al.   TISSUE ENGINEERING PART A

Photocrosslinkable laminin-functionalized polyethylene glycol hydrogel for intervertebral disc regeneration

(2013) Aubrey T. Francisco et al.   Acta Biomaterialia

Injectable alginate hydrogels for cell delivery in tissue engineering

(2013) Sílvia J. Bidarra et al.   Acta Biomaterialia

Injectable laminin-functionalized hydrogel for nucleus pulposus regeneration

(2013) Aubrey T. Francisco et al.   BIOMATERIALS

Needle puncture injury causes acute and long-term mechanical deficiency in a mouse model of intervertebral disc degeneration

(2013) John T. Martin et al.   JOURNAL OF ORTHOPAEDIC RESEARCH

Innervation of pathologies in the lumbar vertebral end plate and intervertebral disc

(2013) Aaron J. Fields et al.   Spine Journal

Dynamic pressurization induces transition of notochordal cells to a mature phenotype while retaining production of important patterning ligands from development

(2013) Devina Purmessur et al.   ARTHRITIS RESEARCH & THERAPY

Laminin-111-derived peptides and cancer

(2013) Yamato Kikkawa et al.   Cell Adhesion & Migration

Diversity of intervertebral disc cells: phenotype and function

(2012) Girish Pattappa et al.   JOURNAL OF ANATOMY

Regeneration of nucleus pulposus tissue in an ovine intervertebral disc degeneration model by cell-free resorbable polymer scaffolds

(2012) Christian Woiciechowsky et al.   Journal of Tissue Engineering and Regenerative Medicine

Maleimide Cross-Linked Bioactive PEG Hydrogel Exhibits Improved Reaction Kinetics and Cross-Linking for Cell Encapsulation and In Situ Delivery

(2011) Edward A. Phelps et al.   ADVANCED MATERIALS

Hypoxia activates the notch signaling pathway in cells of the intervertebral disc: Implications in degenerative disc disease

(2011) Akihiko Hiyama et al.   ARTHRITIS AND RHEUMATISM

Mesenchymal stem cells injection in degenerated intervertebral disc: cell leakage may induce osteophyte formation

(2011) Gianluca Vadalà et al.   Journal of Tissue Engineering and Regenerative Medicine

Structure and Biology of the Intervertebral Disk in Health and Disease

(2011) Wilson C.W. Chan et al.   ORTHOPEDIC CLINICS OF NORTH AMERICA

Extracellular Matrix Ligand and Stiffness Modulate Immature Nucleus Pulposus Cell-Cell Interactions

(2011) Christopher L. Gilchrist et al.   PLoS One

Expression of Laminin Isoforms, Receptors, and Binding Proteins Unique to Nucleus Pulposus Cells of Immature Intervertebral Disc

(2009) Jun Chen et al.   CONNECTIVE TISSUE RESEARCH

Needle Puncture Injury Affects Intervertebral Disc Mechanics and Biology in an Organ Culture Model

(2009) Casey L. Korecki et al.   SPINE

Self-Assembly of Aligned Tissue-Engineered Annulus Fibrosus and Intervertebral Disc Composite Via Collagen Gel Contraction

(2009) Robby D. Bowles et al.   TISSUE ENGINEERING PART A