Type 1 regulatory T cells: a new mechanism of peripheral immune tolerance

Lack of the protein tyrosine phosphatase PTPN22 strengthens transplant tolerance to pancreatic islets in mice

(2015) Georgia Fousteri et al.   DIABETOLOGIA

A B-1a cell subset induces Foxp3− T cells with regulatory activity through an IL-10-independent pathway

(2014) Ling-Hui Hsu et al.   Cellular & Molecular Immunology

Human CD4+CD39+regulatory T cells produce adenosine upon co-expression of surface CD73 or contact with CD73+exosomes or CD73+cells

(2014) P. J. Schuler et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

A novel upstream enhancer ofFOXP3, sensitive to methylation-induced silencing, exhibits dysregulated methylation in rheumatoid arthritis Treg cells

(2014) Alan Kennedy et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Regulatory T cells and their roles in immune dysregulation and allergy

(2014) Laurence Pellerin et al.   IMMUNOLOGIC RESEARCH

CXCL11-dependent induction of FOXP3-negative regulatory T cells suppresses autoimmune encephalomyelitis

(2014) Yaniv Zohar et al.   JOURNAL OF CLINICAL INVESTIGATION

The Production of IL-10 by Human Regulatory T Cells Is Enhanced by IL-2 through a STAT5-Responsive Intronic Enhancer in the IL-10 Locus

(2014) K. Tsuji-Takayama et al.   JOURNAL OF IMMUNOLOGY

Phenotype Alterations in Regulatory T-Cell Subsets in Primary HIV Infection and Identification of Tr1-like Cells as the Main Interleukin 10-Producing CD4+ T Cells

(2014) M. F. Chevalier et al.   JOURNAL OF INFECTIOUS DISEASES

Immunological Outcome in Haploidentical-HSC Transplanted Patients Treated with IL-10-Anergized Donor T Cells

(2014) Rosa Bacchetta et al.   Frontiers in Immunology

Egr-2 transcription factor is required for Blimp-1-mediated IL-10 production in IL-27-stimulated CD4+T cells

(2013) Yukiko Iwasaki et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

IL-27 paves different roads to Tr1

(2013) Ajithkumar Vasanthakumar et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

CD55 Costimulation Induces Differentiation of a Discrete T Regulatory Type 1 Cell Population with a Stable Phenotype

(2013) R. V. Sutavani et al.   JOURNAL OF IMMUNOLOGY

Regulatory T cells: recommendations to simplify the nomenclature

(2013) Abul K Abbas et al.   NATURE IMMUNOLOGY

Coexpression of CD49b and LAG-3 identifies human and mouse T regulatory type 1 cells

(2013) Nicola Gagliani et al.   NATURE MEDICINE

Enhanced GITR/GITRL interactions augment IL-27 expression and induce IL-10-producing Tr-1 like cells

(2012) Yijun Carrier et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Regulatory T-cell therapy for inflammatory bowel disease: more questions than answers

(2012) Megan E. Himmel et al.   IMMUNOLOGY

Interleukin-6 induces the generation of IL-10-producing Tr1 cells and suppresses autoimmune tissue inflammation

(2012) Jun-O Jin et al.   JOURNAL OF AUTOIMMUNITY

Enforced IL-10 Expression Confers Type 1 Regulatory T Cell (Tr1) Phenotype and Function to Human CD4+ T Cells

(2012) Grazia Andolfi et al.   MOLECULAR THERAPY

Probiotic Bifidobacterium breve Induces IL-10-Producing Tr1 Cells in the Colon

(2012) Seong Gyu Jeon et al.   PLoS Pathogens

The Cellular and Molecular Mechanisms of Immuno-Suppression by Human Type 1 Regulatory T Cells

(2012) Silvia Gregori et al.   Frontiers in Immunology

Is ROG, repressor of GATA, a specific regulator of Th2-type immune response?

(2011) Hirohito Kita   CLINICAL IMMUNOLOGY

Killing of myeloid APCs via HLA class I, CD2 and CD226 defines a novel mechanism of suppression by human Tr1 cells

(2011) Chiara F. Magnani et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

IL-2 Regulates Expression of C-MAF in Human CD4 T Cells

(2011) A. Rani et al.   JOURNAL OF IMMUNOLOGY

IFN-  and CD46 stimulation are associated with active lupus and skew natural T regulatory cell differentiation to type 1 regulatory T (Tr1) cells

(2011) H. Le Buanec et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Environmental influences on T regulatory cells in inflammatory bowel disease

(2011) Gijs Hardenberg et al.   SEMINARS IN IMMUNOLOGY

Differentiation of type 1 T regulatory cells (Tr1) by tolerogenic DC-10 requires the IL-10-dependent ILT4/HLA-G pathway

(2010) S. Gregori et al.   BLOOD

The PD-1 pathway in tolerance and autoimmunity

(2010) Loise M. Francisco et al.   IMMUNOLOGICAL REVIEWS

IL-27 induces the differentiation of Tr1-like cells from human naive CD4+ T cells via the phosphorylation of STAT1 and STAT3

(2010) Hui Wang et al.   IMMUNOLOGY LETTERS

Adenosine and Prostaglandin E2Cooperate in the Suppression of Immune Responses Mediated by Adaptive Regulatory T Cells

(2010) Magis Mandapathil et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Role of conserved non-coding DNA elements in the Foxp3 gene in regulatory T-cell fate

(2010) Ye Zheng et al.   NATURE

The aryl hydrocarbon receptor interacts with c-Maf to promote the differentiation of type 1 regulatory T cells induced by IL-27

(2010) Lionel Apetoh et al.   NATURE IMMUNOLOGY

Antigen-Specific Dependence of Tr1-Cell Therapy in Preclinical Models of Islet Transplant

(2009) N. Gagliani et al.   DIABETES

Cutting Edge: IL-27 Induces the Transcription Factor c-Maf, Cytokine IL-21, and the Costimulatory Receptor ICOS that Coordinately Act Together to Promote Differentiation of IL-10-Producing Tr1 Cells

(2009) C. Pot et al.   JOURNAL OF IMMUNOLOGY

CD4+CD25-LAG3+ regulatory T cells controlled by the transcription factor Egr-2

(2009) T. Okamura et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A survey of fully haploidentical hematopoietic stem cell transplantation in adults with high-risk acute leukemia: a risk factor analysis of outcomes for patients in remission at transplantation

(2008) F. Ciceri et al.   BLOOD

DNA methylation controls Foxp3 gene expression

(2008) Julia K. Polansky et al.   EUROPEAN JOURNAL OF IMMUNOLOGY