Intracellular Injection of Brain Extracts from Alzheimer’s Disease Patients Triggers Unregulated Ca2+ Release from Intracellular Stores That Hinders Cellular Bioenergetics

Quantifying the dose-dependent impact of intracellular amyloid beta in a mathematical model of calcium regulation in xenopus oocyte

(2021) Joseph Minicucci et al.   PLoS One

Calcium Dyshomeostasis in Alzheimer’s Disease Pathogenesis

(2021) Roberta Cascella et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Human-Induced Neurons from Presenilin 1 Mutant Patients Model Aspects of Alzheimer’s Disease Pathology

(2020) Sean Schrank et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Alterations of the Endoplasmic Reticulum (ER) Calcium Signaling Molecular Components in Alzheimer’s Disease

(2020) Mounia Chami et al.   Cells

Intra- and extracellular β-amyloid overexpression via adeno-associated virus-mediated gene transfer impairs memory and synaptic plasticity in the hippocampus

(2019) Stefania Forner et al.   Scientific Reports

Calcium hypothesis of neurodegeneration – An update

(2019) Ilya Bezprozvanny   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

DYSREGULATION OF INTRACELLULAR CALCIUM SIGNALING IN ALZHEIMER’S DISEASE

(2018) Elena Popugaeva et al.   ANTIOXIDANTS & REDOX SIGNALING

The Amyloid-β Oligomer Hypothesis: Beginning of the Third Decade

(2018) Erika N. Cline et al.   JOURNAL OF ALZHEIMERS DISEASE

Data-driven modeling of mitochondrial dysfunction in Alzheimer's disease

(2018) Patrick Toglia et al.   CELL CALCIUM

A mathematical model for the effects of amyloid beta on intracellular calcium

(2018) Joe Latulippe et al.   PLoS One

Impaired mitochondrial function due to familial Alzheimer's disease-causing presenilins mutants via Ca2+ disruptions

(2016) Patrick Toglia et al.   CELL CALCIUM

The gain-of-function enhancement of IP3-receptor channel gating by familial Alzheimer's disease-linked presenilin mutants increases the open probability of mitochondrial permeability transition pore

(2016) Patrick Toglia et al.   CELL CALCIUM

Picomolar sensitivity to inositol trisphosphate in Xenopus oocytes

(2015) Angelo Demuro et al.   CELL CALCIUM

Intracellular amyloid and the neuronal origin of Alzheimer neuritic plaques

(2014) Anna Pensalfini et al.   NEUROBIOLOGY OF DISEASE

A Deterministic Model Predicts the Properties of Stochastic Calcium Oscillations in Airway Smooth Muscle Cells

(2014) Pengxing Cao et al.   PLoS Computational Biology

Cytotoxicity of Intracellular A 42 Amyloid Oligomers Involves Ca2+ Release from the Endoplasmic Reticulum by Stimulated Production of Inositol Trisphosphate

(2013) A. Demuro et al.   JOURNAL OF NEUROSCIENCE

Multi-scale data-driven modeling and observation of calcium puffs

(2012) Ghanim Ullah et al.   CELL CALCIUM

Permeant calcium ion feed-through regulation of single inositol 1,4,5-trisphosphate receptor channel gating

(2012) Horia Vais et al.   JOURNAL OF GENERAL PHYSIOLOGY

Single-channel Ca2+imaging implicates Aβ1–42 amyloid pores in Alzheimer’s disease pathology

(2011) Angelo Demuro et al.   JOURNAL OF CELL BIOLOGY

Conformation dependent monoclonal antibodies distinguish different replicating strains or conformers of prefibrillar Aβ oligomers

(2011) Rakez Kayed et al.   Molecular Neurodegeneration

Modulation of Endoplasmic Reticulum Ca2+Store Filling by Cyclic ADP-ribose Promotes Inositol Trisphosphate (IP3)-evoked Ca2+Signals

(2010) Michiko Yamasaki-Mann et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Calcium Signaling and Amyloid Toxicity in Alzheimer Disease

(2010) Angelo Demuro et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Soluble fibrillar oligomer levels are elevated in Alzheimer's disease brain and correlate with cognitive dysfunction

(2009) Jennifer L. Tomic et al.   NEUROBIOLOGY OF DISEASE

Imaging the quantal substructure of single IP3R channel activity during Ca2+ puffs in intact mammalian cells

(2009) I. F. Smith et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA