The gain-of-function enhancement of IP3-receptor channel gating by familial Alzheimer's disease-linked presenilin mutants increases the open probability of mitochondrial permeability transition pore

Title
The gain-of-function enhancement of IP3-receptor channel gating by familial Alzheimer's disease-linked presenilin mutants increases the open probability of mitochondrial permeability transition pore
Authors
Keywords
Presenilins, Alzheimer's disease, Mitochondria, Permeability transition pore, Cell death, Apoptosis
Journal
CELL CALCIUM
Volume 60, Issue 1, Pages 13-24
Publisher
Elsevier BV
Online
2016-05-08
DOI
10.1016/j.ceca.2016.05.002

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