Inactivation of Autophagy in Keratinocytes Reduces Tumor Growth in Mouse Models of Epithelial Skin Cancer

Autophagy in cancer cell remodeling and quality control

(2022) Grace A. Hernandez et al.   MOLECULAR CELL

NIX initiates mitochondrial fragmentation via DRP1 to drive epidermal differentiation

(2021) Cory L. Simpson et al.   Cell Reports

ATG12 deficiency results in intracellular glutamine depletion, abrogation of tumor hypoxia and a favorable prognosis in cancer

(2021) Tom G. Keulers et al.   Autophagy

Autophagy in skin barrier and immune‐related skin diseases

(2021) Chi Liu et al.   JOURNAL OF DERMATOLOGY

Understanding the Role of Autophagy in Cancer Formation and Progression Is a Real Opportunity to Treat and Cure Human Cancers

(2021) Simone Patergnani et al.   Cancers

Autophagy-based unconventional secretion of HMGB1 by keratinocytes plays a pivotal role in psoriatic skin inflammation

(2020) Zhen Wang et al.   Autophagy

Keratinocyte autophagy enables the activation of keratinocytes and fibroblasts and facilitates wound healing

(2020) Lei Qiang et al.   Autophagy

Targeting Autophagy to Treat Cancer: Challenges and Opportunities

(2020) Junghyun Lim et al.   Frontiers in Pharmacology

Peptidylarginine Deiminase Inhibitor Cl-amidine Attenuates Cornification and Interferes with the Regulation of Autophagy in Reconstructed Human Epidermis

(2019) Laura Cau et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Autophagic Control of Skin Aging

(2019) Leopold Eckhart et al.   Frontiers in Cell and Developmental Biology

The ATG conjugation systems in autophagy

(2019) Noboru Mizushima   CURRENT OPINION IN CELL BIOLOGY

Suppression of autophagy perturbs turnover of sequestosome-1/p62 in Merkel cells but not in keratinocytes

(2018) Supawadee Sukseree et al.   JOURNAL OF DERMATOLOGICAL SCIENCE

Suppression of Epithelial Autophagy Compromises the Homeostasis of Sweat Glands during Aging

(2018) Supawadee Sukseree et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

The autophagic network and cancer

(2018) Marissa D. Rybstein et al.   NATURE CELL BIOLOGY

Inactivation of autophagy leads to changes in sebaceous gland morphology and function

(2018) Heidemarie Rossiter et al.   EXPERIMENTAL DERMATOLOGY

Cornification of nail keratinocytes requires autophagy for bulk degradation of intracellular proteins while sparing components of the cytoskeleton

(2018) Karin Jaeger et al.   APOPTOSIS

Microenvironmental autophagy promotes tumour growth

(2017) Nadja S. Katheder et al.   NATURE

Autophagy deficient keratinocytes display increased DNA damage, senescence and aberrant lipid composition after oxidative stress in vitro and in vivo

(2017) Xiuzu Song et al.   Redox Biology

Constitutive Autophagy and Nucleophagy during Epidermal Differentiation

(2016) Olufolake Akinduro et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Pancreatic stellate cells support tumour metabolism through autophagic alanine secretion

(2016) Cristovão M. Sousa et al.   NATURE

Autophagy positively regulates DNA damage recognition by nucleotide excision repair

(2015) Lei Qiang et al.   Autophagy

Autophagy in malignant transformation and cancer progression

(2015) L. Galluzzi et al.   EMBO JOURNAL

The role for autophagy in cancer

(2015) Eileen White   JOURNAL OF CLINICAL INVESTIGATION

The significant role of autophagy in the granular layer in normal skin differentiation and hair growth

(2014) Nagisa Yoshihara et al.   ARCHIVES OF DERMATOLOGICAL RESEARCH

Milestones in Skin Carcinogenesis: The Biology of Multistage Carcinogenesis

(2014) Allan Balmain et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

A dual role for autophagy in a murine model of lung cancer

(2014) Shuan Rao et al.   Nature Communications

Autophagy Is Critical for Pancreatic Tumor Growth and Progression in Tumors with p53 Alterations

(2014) A. Yang et al.   Cancer Discovery

Autophagy suppresses progression of K-ras-induced lung tumors to oncocytomas and maintains lipid homeostasis

(2013) J. Y. Guo et al.   GENES & DEVELOPMENT

Epidermal keratinocytes form a functional skin barrier in the absence of Atg7 dependent autophagy

(2013) Heidemarie Rossiter et al.   JOURNAL OF DERMATOLOGICAL SCIENCE

p53 status determines the role of autophagy in pancreatic tumour development

(2013) Mathias T. Rosenfeldt et al.   NATURE

Targeted deletion of Atg5 reveals differential roles of autophagy in keratin K5-expressing epithelia

(2012) Supawadee Sukseree et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Autophagy Controls p38 Activation to Promote Cell Survival under Genotoxic Stress

(2012) Lei Qiang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Autophagy in the Thymic Epithelium Is Dispensable for the Development of Self-Tolerance in a Novel Mouse Model

(2012) Supawadee Sukseree et al.   PLoS One

Autophagy: Renovation of Cells and Tissues

(2011) Noboru Mizushima et al.   CELL

Autophagy-deficient mice develop multiple liver tumors

(2011) A. Takamura et al.   GENES & DEVELOPMENT

Autocrine VEGF Signaling Synergizes with EGFR in Tumor Cells to Promote Epithelial Cancer Development

(2010) Beate M. Lichtenberger et al.   CELL

Autophagy Suppresses Tumorigenesis through Elimination of p62

(2009) Robin Mathew et al.   CELL