Autophagy in skin barrier and immune‐related skin diseases

In Situ Self-Assembly Nanomicelle Microneedles for Enhanced Photoimmunotherapy via Autophagy Regulation Strategy

(2021) Minglong Chen et al.   ACS Nano

Daturataturin A, a withanolide in Datura metel L., induces HaCaT autophagy through the PI3K‐Akt‐mTOR signaling pathway

(2021) Zheng Wei et al.   PHYTOTHERAPY RESEARCH

Autophagy-based unconventional secretion of HMGB1 by keratinocytes plays a pivotal role in psoriatic skin inflammation

(2020) Zhen Wang et al.   Autophagy

Metformin Suppresses LPS-Induced Inflammatory Responses in Macrophage and Ameliorates Allergic Contact Dermatitis in Mice via Autophagy

(2020) Mengjie Wang et al.   BIOLOGICAL & PHARMACEUTICAL BULLETIN

Role of Aryl Hydrocarbon Receptor Activation and Autophagy in Psoriasis-Related Inflammation

(2020) Hye Ran Kim et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

IL-37 Ameliorating Allergic Inflammation in Atopic Dermatitis Through Regulating Microbiota and AMPK-mTOR Signaling Pathway-Modulated Autophagy Mechanism

(2020) Tianheng Hou et al.   Frontiers in Immunology

Topical application of autophagy‐activating peptide improved skin barrier function and reduced acne symptoms in acne‐prone skin

(2020) Yoonjin Lee et al.   Journal of Cosmetic Dermatology

Autophagy Receptor Tollip Facilitates Bacterial Autophagy by Recruiting Galectin-7 in Response to Group A Streptococcus Infection

(2020) Ching-Yu Lin et al.   Frontiers in Cellular and Infection Microbiology

The Beneficial Role of Sunitinib in Tumor Immune Surveillance by Regulating Tumor PD‐L1

(2020) Hui Li et al.   Advanced Science

Vitamin D improves sunburns by increasing autophagy in M2 macrophages

(2019) Lopa. M. Das et al.   Autophagy

Insights into atopic dermatitis gained from genetically defined mouse models

(2019) Saeko Nakajima et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Cis-khellactone inhibited the proinflammatory macrophages via promoting autophagy to ameliorate imiquimod-induced psoriasis

(2019) Lili Feng et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Autophagy Activation by Crepidiastrum Denticulatum Extract Attenuates Environmental Pollutant-Induced Damage in Dermal Fibroblasts

(2019) Seok Yoon et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Regulation of the innate immune system by autophagy: monocytes, macrophages, dendritic cells and antigen presentation

(2019) Nina Germic et al.   CELL DEATH AND DIFFERENTIATION

Group A Streptococcus modulates RAB1- and PIK3C3 complex-dependent autophagy

(2019) Hirotaka Toh et al.   Autophagy

Noncanonical autophagy in dermal dendritic cells mediates immunosuppressive effects of UV exposure

(2019) Payel Sil et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

PI3K/AKT/mTOR activation and autophagy inhibition plays a key role in increased cholesterol during IL-17A mediated inflammatory response in psoriasis

(2018) Pallavi Varshney et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Lysosomes Support the Degradation, Signaling, and Mitochondrial Metabolism Necessary for Human Epidermal Differentiation

(2018) Christine L. Monteleon et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Autophagy promotes MSC-mediated vascularization in cutaneous wound healing via regulation of VEGF secretion

(2018) Y. An et al.   Cell Death & Disease

A tryptophan metabolite of the skin microbiota attenuates inflammation in patients with atopic dermatitis through the aryl hydrocarbon receptor

(2018) Jinlei Yu et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

The effect of autophagy-enhancing peptide in moisturizer on atopic dermatitis: a randomized controlled trial

(2018) Soon Hyo Kwon et al.   JOURNAL OF DERMATOLOGICAL TREATMENT

Pterostilbene Attenuates Hexavalent Chromium-Induced Allergic Contact Dermatitis by Preventing Cell Apoptosis and Inhibiting IL-1β-Related NLRP3 Inflammasome Activation

(2018) Bour-Jr Wang et al.   Journal of Clinical Medicine

Tregs restrain dendritic cell autophagy to ameliorate autoimmunity

(2017) Themis Alissafi et al.   JOURNAL OF CLINICAL INVESTIGATION

Targeting autophagy inhibits melanoma growth by enhancing NK cells infiltration in a CCL5-dependent manner

(2017) Takouhie Mgrditchian et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Autophagy Is an Innate Mechanism Associated with Leprosy Polarization

(2017) Bruno Jorge de Andrade Silva et al.   PLoS Pathogens

Autophagy deficient keratinocytes display increased DNA damage, senescence and aberrant lipid composition after oxidative stress in vitro and in vivo

(2017) Xiuzu Song et al.   Redox Biology

Vitiligo: Pathogenesis, clinical variants and treatment approaches

(2016) Giannicola Iannella et al.   AUTOIMMUNITY REVIEWS

Exogenous hydrogen sulfide promotes cell proliferation and differentiation by modulating autophagy in human keratinocytes

(2016) Xin Xie et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

PGRN Suppresses Inflammation and Promotes Autophagy in Keratinocytes Through the Wnt/β-Catenin Signaling Pathway

(2016) Rong Tian et al.   INFLAMMATION

Sequential steps of macroautophagy and chaperone-mediated autophagy are involved in the irreversible process of posterior silk gland histolysis during metamorphosis ofBombyx mori

(2016) Hajime Shiba et al.   JOURNAL OF EXPERIMENTAL BIOLOGY

Roseotoxin B Improves Allergic Contact Dermatitis through a Unique Anti-Inflammatory Mechanism Involving Excessive Activation of Autophagy in Activated T Lymphocytes

(2016) Xingqi Wang et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Constitutive Autophagy and Nucleophagy during Epidermal Differentiation

(2016) Olufolake Akinduro et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

AP1S3 Mutations Cause Skin Autoinflammation by Disrupting Keratinocyte Autophagy and Up-Regulating IL-36 Production

(2016) Satveer K. Mahil et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Atopic dermatitis

(2016) Stephan Weidinger et al.   LANCET

Autophagy as a Melanocytic Self-Defense Mechanism

(2015) Vijayasaradhi Setaluri   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Suppression of Autophagy Dysregulates the Antioxidant Response and Causes Premature Senescence of Melanocytes

(2015) Cheng-Feng Zhang et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Regulation of endoplasmic reticulum turnover by selective autophagy

(2015) Aliaksandr Khaminets et al.   NATURE

Methicillin-Resistant Staphylococcus aureus Adaptation to Human Keratinocytes

(2015) Grace Soong et al.   mBio

Vitiligo

(2015) Mauro Picardo et al.   Nature Reviews Disease Primers

AP1S3 Mutations Are Associated with Pustular Psoriasis and Impaired Toll-like Receptor 3 Trafficking

(2014) Niovi Setta-Kaffetzi et al.   AMERICAN JOURNAL OF HUMAN GENETICS

AMPK inhibits cardiac hypertrophy by promoting autophagy via mTORC1

(2014) Yanh Li et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

The significant role of autophagy in the granular layer in normal skin differentiation and hair growth

(2014) Nagisa Yoshihara et al.   ARCHIVES OF DERMATOLOGICAL RESEARCH

FGF7/KGF regulates autophagy in keratinocytes

(2014) Francesca Belleudi et al.   Autophagy

Autophagy induced by resveratrol suppressesα-MSH-induced melanogenesis

(2014) Eun Sung Kim et al.   EXPERIMENTAL DERMATOLOGY

Regulation of autophagy: Modulation of the size and number of autophagosomes

(2014) Meiyan Jin et al.   FEBS LETTERS

Oxidative stress-dependent activation of the eIF2α–ATFr unfolded protein response branch by skin sensitizer 1-fluoro-2,4-dinitrobenzene modulates dendritic-like cell maturation and inflammatory status in a biphasic manner

(2014) Andreia Luís et al.   FREE RADICAL BIOLOGY AND MEDICINE

iASPP is a novel autophagy inhibitor in keratinocytes

(2014) A. Chikh et al.   JOURNAL OF CELL SCIENCE

Defects in Skin    T Cell Function Contribute to Delayed Wound Repair in Rapamycin-Treated Mice

(2014) R. E. Mills et al.   JOURNAL OF IMMUNOLOGY

Autophagic flux without a block differentiates varicella-zoster virus infection from herpes simplex virus infection

(2014) Erin M. Buckingham et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Autophagy inDrosophila: From Historical Studies to Current Knowledge

(2014) Nitha C. Mulakkal et al.   Biomed Research International

The intricacy of nuclear membrane dynamics during nucleophagy

(2014) Dalibor Mijaljica et al.   Nucleus

The Globally Disseminated M1T1 Clone of Group A Streptococcus Evades Autophagy for Intracellular Replication

(2013) Timothy C. Barnett et al.   Cell Host & Microbe

Autophagy plays a WASHing game

(2013) Nicolas Dupont et al.   EMBO JOURNAL

ARP101 inhibits α-MSH-stimulated melanogenesis by regulation of autophagy in melanocytes

(2013) Eun Sung Kim et al.   FEBS LETTERS

New concept of the pathogenesis of atopic dermatitis: Interplay among the barrier, allergy, and pruritus as a trinity

(2013) Kenji Kabashima   JOURNAL OF DERMATOLOGICAL SCIENCE

Autophagy Has a Significant Role in Determining Skin Color by Regulating Melanosome Degradation in Keratinocytes

(2013) Daiki Murase et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

In Vivo Silencing of the Transcription Factor IRF5 Reprograms the Macrophage Phenotype and Improves Infarct Healing

(2013) Gabriel Courties et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Resveratrol Couples Apoptosis with Autophagy in UVB-Irradiated HaCaT Cells

(2013) Nicoletta Vitale et al.   PLoS One

Inflammasome Components Coordinate Autophagy and Pyroptosis as Macrophage Responses to Infection

(2013) B. G. Byrne et al.   mBio

A possible cross-talk between autophagy and apoptosis in generating an immune response in melanoma

(2012) Azim Hossain et al.   APOPTOSIS

Macrophage Autophagy in Immunity to Cryptococcus neoformans and Candida albicans

(2012) André Moraes Nicola et al.   INFECTION AND IMMUNITY

Noncanonical E2 recruitment by the autophagy E1 revealed by Atg7–Atg3 and Atg7–Atg10 structures

(2012) Stephen E Kaiser et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Atopic dermatitis: a disease of altered skin barrier and immune dysregulation

(2011) Mark Boguniewicz et al.   IMMUNOLOGICAL REVIEWS

Crucial role for autophagy in degranulation of mast cells

(2011) Hiroko Ushio et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Calcipotriol Induces Autophagy in HeLa Cells and Keratinocytes

(2011) Richard C. Wang et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Role of AMPK-mTOR-Ulk1/2 in the Regulation of Autophagy: Cross Talk, Shortcuts, and Feedbacks

(2011) S. Alers et al.   MOLECULAR AND CELLULAR BIOLOGY

Autophagy in immunity and inflammation

(2011) Beth Levine et al.   NATURE

Functional Analysis of Host Factors that Mediate the Intracellular Lifestyle of Cryptococcus neoformans

(2011) Qing-Ming Qin et al.   PLoS Pathogens

Methods in Mammalian Autophagy Research

(2010) Noboru Mizushima et al.   CELL

Association of UVRAG polymorphisms with susceptibility to non-segmental vitiligo in a Korean sample

(2010) Taek-Jo Jeong et al.   EXPERIMENTAL DERMATOLOGY

Autophagy in human keratinocytes: an early step of the differentiation?

(2010) Elodie Aymard et al.   EXPERIMENTAL DERMATOLOGY

In Vivo Requirement for Atg5 in Antigen Presentation by Dendritic Cells

(2010) Heung Kyu Lee et al.   IMMUNITY

Autophagy Negatively Regulates Keratinocyte Inflammatory Responses via Scaffolding Protein p62/SQSTM1

(2010) H.-M. Lee et al.   JOURNAL OF IMMUNOLOGY

A Noncanonical Mechanism of Nrf2 Activation by Autophagy Deficiency: Direct Interaction between Keap1 and p62

(2010) A. Lau et al.   MOLECULAR AND CELLULAR BIOLOGY

In vivo function of Langerhans cells and dermal dendritic cells

(2010) Daniel H. Kaplan   TRENDS IN IMMUNOLOGY

ULK1·ATG13·FIP200 Complex Mediates mTOR Signaling and Is Essential for Autophagy

(2009) Ian G. Ganley et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Skin-Resident T Cells: The Ups and Downs of On Site Immunity

(2009) Rachael A. Clark   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Varicella-Zoster Virus Infection Induces Autophagy in both Cultured Cells and Human Skin Vesicles

(2009) M.-N. Takahashi et al.   JOURNAL OF VIROLOGY

ULK-Atg13-FIP200 Complexes Mediate mTOR Signaling to the Autophagy Machinery

(2009) Chang Hwa Jung et al.   MOLECULAR BIOLOGY OF THE CELL

Autophagy enhances the presentation of endogenous viral antigens on MHC class I molecules during HSV-1 infection

(2009) Luc English et al.   NATURE IMMUNOLOGY

The susceptibility to vitiligo is associated with NF-E2-related factor2 (Nrf2) gene polymorphisms: a study on Chinese Han population

(2008) Cui-Ping Guan et al.   EXPERIMENTAL DERMATOLOGY

Autophagy fights disease through cellular self-digestion

(2008) Noboru Mizushima et al.   NATURE

Beclin1-binding UVRAG targets the class C Vps complex to coordinate autophagosome maturation and endocytic trafficking

(2008) Chengyu Liang et al.   NATURE CELL BIOLOGY