Macrophage Sprouty4 deficiency diminishes sepsis-induced acute lung injury in mice

Fibronectin type III domain‐containing 5 improves aging‐related cardiac dysfunction in mice

(2022) Can Hu et al.   AGING CELL

AUF1 protects against ferroptosis to alleviate sepsis-induced acute lung injury by regulating NRF2 and ATF3

(2022) Yichun Wang et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

HO-1 Upregulation by Kaempferol via ROS-Dependent Nrf2-ARE Cascade Attenuates Lipopolysaccharide-Mediated Intercellular Cell Adhesion Molecule-1 Expression in Human Pulmonary Alveolar Epithelial Cells

(2022) Chien-Chung Yang et al.   Antioxidants

Endothelial ERG alleviates cardiac fibrosis via blocking endothelin-1-dependent paracrine mechanism

(2021) Xin Zhang et al.   CELL BIOLOGY AND TOXICOLOGY

Regulation of Bcl-XL by non-canonical NF-κB in the context of CD40-induced drug resistance in CLL

(2021) Marco Haselager et al.   CELL DEATH AND DIFFERENTIATION

The Mitochondrial Redistribution of eNOS is involved in Lipopolysaccharide Induced Inflammasome Activation During Acute Lung Injury

(2021) Hui Wang et al.   Redox Biology

Epithelium- and endothelium-derived exosomes regulate the alveolar macrophages by targeting RGS1 mediated calcium signaling-dependent immune response

(2021) Zunyong Feng et al.   CELL DEATH AND DIFFERENTIATION

The long non-coding RNA PFI protects against pulmonary fibrosis by interacting with splicing regulator SRSF1

(2021) Jian Sun et al.   CELL DEATH AND DIFFERENTIATION

Dexmedetomidine ameliorates endotoxin-induced acute lung injury in vivo and in vitro by preserving mitochondrial dynamic equilibrium through the HIF-1a/HO-1 signaling pathway

(2021) Jia Shi et al.   Redox Biology

NF‐κB/IKK activation by small extracellular vesicles within the SASP

(2021) Juan Antonio Fafián‐Labora et al.   AGING CELL

Chloride channel accessory 1 integrates chloride channel activity and mTORC1 in aging‐related kidney injury

(2021) Hak Joo Lee et al.   AGING CELL

YTHDC1-mediated augmentation of miR-30d in repressing pancreatic tumorigenesis via attenuation of RUNX1-induced transcriptional activation of Warburg effect

(2021) Yichao Hou et al.   CELL DEATH AND DIFFERENTIATION

AMPK-mediated phosphorylation enhances the auto-inhibition of TBC1D17 to promote Rab5-dependent glucose uptake

(2021) Xi Sheng Rao et al.   CELL DEATH AND DIFFERENTIATION

Osteocrin, a novel myokine, prevents diabetic cardiomyopathy via restoring proteasomal activity

(2021) Xin Zhang et al.   Cell Death & Disease

rhKGF-2 Attenuates Smoke Inhalation Lung Injury of Rats via Activating PI3K/Akt/Nrf2 and Repressing FoxO1-NLRP3 Inflammasome

(2021) Zhonghua Fu et al.   Frontiers in Pharmacology

Intraocular iron injection induces oxidative stress followed by elements of geographic atrophy and sympathetic ophthalmia

(2021) Yingrui Liu et al.   AGING CELL

Dietary citrate supplementation enhances longevity, metabolic health, and memory performance through promoting ketogenesis

(2021) Shou‐Zen Fan et al.   AGING CELL

Nuclear UHRF1 is a gate-keeper of cellular AMPK activity and function

(2021) Xiang Xu et al.   CELL RESEARCH

Macrophage NFATc3 prevents foam cell formation and atherosclerosis: evidence and mechanisms

(2021) Xiu Liu et al.   EUROPEAN HEART JOURNAL

Macrophage nuclear factor erythroid 2‐related factor 2 deficiency promotes innate immune activation by tissue inhibitor of metalloproteinase 3–mediated RhoA/ROCK pathway in the ischemic liver

(2021) Jianhua Rao et al.   HEPATOLOGY

The immunology of sepsis

(2021) Tom van der Poll et al.   IMMUNITY

Alveolar macrophage - derived exosomes modulate severity and outcome of acute lung injury

(2020) Cong Ye et al.   Aging-US

Cutaneous lewisite exposure causes acute lung injury

(2020) Shajer Manzoor et al.   Annals of the New York Academy of Sciences

A novel Sprouty4-ERK1/2-Wnt/β-catenin regulatory loop in marrow stromal progenitor cells controls osteogenic and adipogenic differentiation

(2020) Lijie Tian et al.   METABOLISM-CLINICAL AND EXPERIMENTAL

Chelidonine Selectively Inhibits the Growth of Gefitinib-resistant Non-small Cell Lung Cancer Cells through the EGFR-AMPK Pathway

(2020) Ya-Jia Xie et al.   PHARMACOLOGICAL RESEARCH

Matrine attenuates pathological cardiac fibrosis via RPS5/p38 in mice

(2020) Xin Zhang et al.   ACTA PHARMACOLOGICA SINICA

Alveolar Epithelial Cells Promote IGF-1 Production by Alveolar Macrophages Through TGF-β to Suppress Endogenous Inflammatory Signals

(2020) Mimi Mu et al.   Frontiers in Immunology

Osteocrin attenuates inflammation, oxidative stress, apoptosis, and cardiac dysfunction in doxorubicin‐induced cardiotoxicity

(2020) Can Hu et al.   Clinical and Translational Medicine

Branched-chain amino acid aminotransferase 2 regulates ferroptotic cell death in cancer cells

(2020) Kang Wang et al.   CELL DEATH AND DIFFERENTIATION

TYK2 licenses non-canonical inflammasome activation during endotoxemia

(2020) Andrea Poelzl et al.   CELL DEATH AND DIFFERENTIATION

MicroRNA-31-5p Exacerbates Lipopolysaccharide-Induced Acute Lung Injury via Inactivating Cab39/AMPKα Pathway

(2020) Wan-li Jiang et al.   Oxidative Medicine and Cellular Longevity

LINC00857 Interacting with YBX1 to Regulate Apoptosis and Autophagy via MET and Phosphor-AMPKa Signaling

(2020) Wenmei Su et al.   Molecular Therapy-Nucleic Acids

Cross-Talk Between Alveolar Macrophages and Lung Epithelial Cells is Essential to Maintain Lung Homeostasis

(2020) Elyse Y. Bissonnette et al.   Frontiers in Immunology

Meteorin-like protein attenuates doxorubicin-induced cardiotoxicity via activating cAMP/PKA/SIRT1 pathway

(2020) Can Hu et al.   Redox Biology

RAC1 nitration at Y32 IS involved in the endothelial barrier disruption associated with lipopolysaccharide-mediated acute lung injury

(2020) Ting Wang et al.   Redox Biology

Songorine promotes cardiac mitochondrial biogenesis via Nrf2 induction during sepsis

(2020) Yi Li et al.   Redox Biology

Matrine attenuates oxidative stress and cardiomyocyte apoptosis in doxorubicin-induced cardiotoxicity via maintaining AMPKα/UCP2 pathway

(2019) Can Hu et al.   Acta Pharmaceutica Sinica B

PAR2-Mediated cAMP Generation Suppresses TRPV4-Dependent Ca2+ Signaling in Alveolar Macrophages to Resolve TLR4-Induced Inflammation

(2019) Sheikh Rayees et al.   Cell Reports

FNDC5 alleviates oxidative stress and cardiomyocyte apoptosis in doxorubicin-induced cardiotoxicity via activating AKT

(2019) Xin Zhang et al.   CELL DEATH AND DIFFERENTIATION

Galectin-1 ameliorates lipopolysaccharide-induced acute lung injury via AMPK-Nrf2 pathway in mice

(2019) Xiao-Ting Huang et al.   FREE RADICAL BIOLOGY AND MEDICINE

MiR-31 Mediates Inflammatory Signaling to Promote Re-Epithelialization during Skin Wound Healing

(2018) Jianyun Shi et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Rosmarinic acid attenuates cardiac fibrosis following long-term pressure overload via AMPKα/Smad3 signaling

(2018) Xin Zhang et al.   Cell Death & Disease

Tissue Unit-ed: Lung Cells Team up to Drive Alveolar Macrophage Development

(2018) Charlotte L. Scott et al.   CELL

siRNA mediated down-regulation of Sprouty2/4 diminishes ischemic brain injury

(2016) Lars Klimaschewski et al.   NEUROSCIENCE LETTERS

Decreased anti-regenerative effects after spinal cord injury in spry4−/− mice

(2015) Y. Goldshmit et al.   NEUROSCIENCE

Loss of Sprouty4 in T cells ameliorates experimental autoimmune encephalomyelitis in mice by negatively regulating IL-1β receptor expression

(2014) Tomohiro Fukaya et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Sprouty4 regulates endothelial cell migration via modulating integrin β3 stability through c-Src

(2013) Yan Gong et al.   ANGIOGENESIS

Broad Suppression of NADPH Oxidase Activity Exacerbates Ischemia/Reperfusion Injury Through Inadvertent Downregulation of Hypoxia-inducible Factor-1α and Upregulation of Peroxisome Proliferator–activated Receptor-α

(2013) Shouji Matsushima et al.   CIRCULATION RESEARCH

Expression of Sproutys and SPREDs is decreased during lung branching morphogenesis in nitrofen-induced pulmonary hypoplasia

(2013) Florian Friedmacher et al.   PEDIATRIC SURGERY INTERNATIONAL

Sprouty Proteins Are Negative Regulators of Interferon (IFN) Signaling and IFN-inducible Biological Responses

(2012) Bhumika Sharma et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Macrophage Tumor Necrosis Factor-α Induces Epithelial Expression of Granulocyte–Macrophage Colony-stimulating Factor

(2009) Lidija Cakarova et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Sprouty4 negatively regulates protein kinase C activation by inhibiting phosphatidylinositol 4,5-biphosphate hydrolysis

(2009) T Ayada et al.   ONCOGENE

Suppression of Sproutys Has a Therapeutic Effect for a Mouse Model of Ischemia by Enhancing Angiogenesis

(2009) Koji Taniguchi et al.   PLoS One