Macrophage nuclear factor erythroid 2‐related factor 2 deficiency promotes innate immune activation by tissue inhibitor of metalloproteinase 3–mediated RhoA/ROCK pathway in the ischemic liver

Nrf2 regulates cell motility through RhoA–ROCK1 signalling in non-small-cell lung cancer cells

(2021) Eunsun Ko et al.   Scientific Reports

TRPV1 alleviates osteoarthritis by inhibiting M1 macrophage polarization via Ca2+/CaMKII/Nrf2 signaling pathway

(2021) Zhongyang Lv et al.   Cell Death & Disease

Auranofin-Mediated NRF2 Induction Attenuates Interleukin 1 Beta Expression in Alveolar Macrophages

(2021) Stephanie B. Wall et al.   Antioxidants

IRG1/Itaconate Activates Nrf2 in Hepatocytes to Protect Against Liver Ischemia–Reperfusion Injury

(2020) Zhongjie Yi et al.   HEPATOLOGY

Alternatively activated macrophages promote resolution of necrosis following acute liver injury

(2020) Philip Starkey Lewis et al.   JOURNAL OF HEPATOLOGY

Integration of miRNA‐regulatory networks in hepatic stellate cells identifies TIMP3 as a key factor in chronic liver disease

(2020) Fida Azar et al.   LIVER INTERNATIONAL

Biology of Tissue Inhibitor of Metalloproteinase 3 (TIMP3), and Its Therapeutic Implications in Cardiovascular Pathology

(2020) Dong Fan et al.   Frontiers in Physiology

Nrf2-regulated redox signaling in brain endothelial cells adapted to physiological oxygen levels: Consequences for sulforaphane mediated protection against hypoxia-reoxygenation

(2020) Gabriela Warpsinski et al.   Redox Biology

Nogo-B is a key mediator of hepatic ischemia and reperfusion injury

(2020) Jianhua Rao et al.   Redox Biology

Small-molecule inhibitors of cyclophilins block opening of the mitochondrial permeability transition pore and protect mice from hepatic ischemia–reperfusion injury

(2019) Mathieu Panel et al.   GASTROENTEROLOGY

Tissue Inhibitor of Metalloproteinase 3 Deficiency Disrupts the Hepatocyte E‐Cadherin/β‐Catenin Complex and Induces Cell Death in Liver Ischemia/Reperfusion Injury

(2019) Takehiro Fujii et al.   LIVER TRANSPLANTATION

Myeloid Notch1 deficiency activates the RhoA/ROCK pathway and aggravates hepatocellular damage in mouse ischemic livers

(2018) Ling Lu et al.   HEPATOLOGY

The Crosstalk between Nrf2 and Inflammasomes

(2018) Paulina Hennig et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Glycogen synthase kinase 3β promotes liver innate immune activation by restraining AMP-activated protein kinase activation

(2018) Haoming Zhou et al.   JOURNAL OF HEPATOLOGY

Canonical and non-canonical mechanisms of Nrf2 activation

(2018) Carlos Alfredo Silva-Islas et al.   PHARMACOLOGICAL RESEARCH

Stress-sensing mechanisms and the physiological roles of the Keap1–Nrf2 system during cellular stress

(2017) Takafumi Suzuki et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Small Maf proteins (MafF, MafG, MafK): History, structure and function

(2016) Fumiki Katsuoka et al.   GENE

The myeloid heat shock transcription factor 1/β-catenin axis regulates NLR family, pyrin domain-containing 3 inflammasome activation in mouse liver ischemia/reperfusion injury

(2016) Shi Yue et al.   HEPATOLOGY

Chemokine (C-C motif) receptor 2-positive monocytes aggravate the early phase of acetaminophen-induced acute liver injury

(2016) Jana C. Mossanen et al.   HEPATOLOGY

NRF2 promotes breast cancer cell proliferation and metastasis by increasing RhoA/ROCK pathway signal transduction

(2016) Chao Zhang et al.   Oncotarget

ATF6 Mediates a Pro-Inflammatory Synergy Between ER Stress and TLR Activation in the Pathogenesis of Liver Ischemia-Reperfusion Injury

(2014) J. Rao et al.   AMERICAN JOURNAL OF TRANSPLANTATION

ATF3-Mediated NRF2/HO-1 Signaling Regulates TLR4 Innate Immune Responses in Mouse Liver Ischemia/Reperfusion Injury

(2014) J. Rao et al.   AMERICAN JOURNAL OF TRANSPLANTATION

Loss of the Timp gene family is sufficient for the acquisition of the CAF-like cell state

(2014) Masayuki Shimoda et al.   NATURE CELL BIOLOGY

TIMP3 controls cell fate to confer hepatocellular carcinoma resistance

(2014) V Defamie et al.   ONCOGENE

Advanced glycation endproducts induce fibrogenic activity in nonalcoholic steatohepatitis by modulating TNF-α-converting enzyme activity in mice

(2013) Joy X. Jiang et al.   HEPATOLOGY

ASC/caspase-1/IL-1β signaling triggers inflammatory responses by promoting HMGB1 induction in liver ischemia/reperfusion injury

(2013) Naoko Kamo et al.   HEPATOLOGY

KEAP1-NRF2 complex in ischemia-induced hepatocellular damage of mouse liver transplants

(2013) Bibo Ke et al.   JOURNAL OF HEPATOLOGY

Neuroprotective effect of melatonin against ischemia is partially mediated by alpha-7 nicotinic receptor modulation and HO-1 overexpression

(2013) Esther Parada et al.   JOURNAL OF PINEAL RESEARCH

Fumarate Is Cardioprotective via Activation of the Nrf2 Antioxidant Pathway

(2012) Houman Ashrafian et al.   Cell Metabolism

Ginsenoside Rb1 Attenuates Intestinal Ischemia Reperfusion Induced Renal Injury by Activating Nrf2/ARE Pathway

(2012) Qian Sun et al.   MOLECULES

Ischaemia–reperfusion injury in liver transplantation—from bench to bedside

(2012) Yuan Zhai et al.   Nature Reviews Gastroenterology & Hepatology

Reactive oxygen species-dependent RhoA activation mediates collagen synthesis in hyperoxic lung fibrosis

(2011) Dmitry Kondrikov et al.   FREE RADICAL BIOLOGY AND MEDICINE

Nrf2 has a protective role against neuronal and capillary degeneration in retinal ischemia–reperfusion injury

(2011) Yanhong Wei et al.   FREE RADICAL BIOLOGY AND MEDICINE

Rho inhibitor prevents ischemia–reperfusion injury in rat steatotic liver

(2011) Shintaro Kuroda et al.   JOURNAL OF HEPATOLOGY

Hydrogen Sulfide Mediates Cardioprotection Through Nrf2 Signaling

(2009) John W. Calvert et al.   CIRCULATION RESEARCH

Activation of Rho Kinase Isoforms in Lung Endothelial Cells during Inflammation

(2009) P. Y. Mong et al.   JOURNAL OF IMMUNOLOGY

Loss of TIMP3 Enhances Interstitial Nephritis and Fibrosis

(2009) Z. Kassiri et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Transcription factor Nrf2 is protective during ischemic and nephrotoxic acute kidney injury in mice

(2009) Manchang Liu et al.   KIDNEY INTERNATIONAL

Adoptive Transfer of Ex Vivo HO-1 Modified Bone Marrow–derived Macrophages Prevents Liver Ischemia and Reperfusion Injury

(2009) Bibo Ke et al.   MOLECULAR THERAPY

Radical-free biology of oxidative stress

(2008) Dean P. Jones   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Aldosterone and Angiotensin II Synergistically Stimulate Migration in Vascular Smooth Muscle Cells Through c-Src-Regulated Redox-Sensitive RhoA Pathways

(2008) A.C. Montezano et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY