Beneficial effect of the short-chain fatty acid propionate on vascular calcification through intestinal microbiota remodelling

The effect of short-chain fatty acids on glycemic control in humans: A systematic review and Meta-analysis

(2022) Anna Cherta-Murillo et al.   AMERICAN JOURNAL OF CLINICAL NUTRITION

Extracellular Vesicles From LPS-Treated Macrophages Aggravate Smooth Muscle Cell Calcification by Propagating Inflammation and Oxidative Stress

(2022) Linda Yaker et al.   Frontiers in Cell and Developmental Biology

Depletion of acetate-producing bacteria from the gut microbiota facilitates cognitive impairment through the gut-brain neural mechanism in diabetic mice

(2021) Hong Zheng et al.   Microbiome

The Protective Effects of Live and Pasteurized Akkermansia muciniphila and Its Extracellular Vesicles against HFD/CCl4-Induced Liver Injury

(2021) Shahrbanoo Keshavarz Azizi Raftar et al.   Microbiology Spectrum

Greater Dietary Inflammatory Potential Is Associated With Higher Likelihood of Abdominal Aortic Calcification

(2021) Zheng Qin et al.   Frontiers in Cardiovascular Medicine

The Emerging Biotherapeutic Agent: Akkermansia

(2021) Vipin Chandra Kalia et al.   INDIAN JOURNAL OF MICROBIOLOGY

The role of Akkermansia muciniphila in obesity, diabetes and atherosclerosis

(2021) Alka Hasani et al.   JOURNAL OF MEDICAL MICROBIOLOGY

Leveraging diet to engineer the gut microbiome

(2021) Mathis Wolter et al.   Nature Reviews Gastroenterology & Hepatology

Trimethylamine-N-Oxide Promotes Vascular Calcification Through Activation of NLRP3 (Nucleotide-Binding Domain, Leucine-Rich-Containing Family, Pyrin Domain-Containing-3) Inflammasome and NF-κB (Nuclear Factor κB) Signals

(2020) Xiuli Zhang et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Function of Akkermansia muciniphila in Obesity: Interactions With Lipid Metabolism, Immune Response and Gut Systems

(2020) Yu Xu et al.   Frontiers in Microbiology

The effects of serum iron level without anemia on long-term prognosis of patients with coronary heart disease complicated with chronic heart failure: a retrospective cohort study

(2020) Jianlong Yan et al.   HEART AND VESSELS

Statin therapy is associated with lower prevalence of gut microbiota dysbiosis

(2020) Sara Vieira-Silva et al.   NATURE

Modest Sodium Reduction Increases Circulating Short-Chain Fatty Acids in Untreated Hypertensives

(2020) Li Chen et al.   HYPERTENSION

Trimethylamine-N-Oxide Promotes Age-Related Vascular Oxidative Stress and Endothelial Dysfunction in Mice and Healthy Humans

(2020) Vienna E. Brunt et al.   HYPERTENSION

Exercise Ameliorates Insulin Resistance of Type 2 Diabetes through Motivating Short-Chain Fatty Acid-Mediated Skeletal Muscle Cell Autophagy

(2020) Ling Yang et al.   Biology-Basel

Intestinal barrier dysfunction as a therapeutic target for cardiovascular disease

(2020) Caitlin Vanessa Lewis et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Beneficial Effects of Newly Isolated Akkermansia muciniphila Strains from the Human Gut on Obesity and Metabolic Dysregulation

(2020) Meng Yang et al.   Microorganisms

Serum metabolic profiling identified a distinct metabolic signature in Bladder Cancer Smokers: A key metabolic enzymes associated with patient survival

(2019) Chandra Sekhar Amara et al.   CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION

Bacteroides vulgatus and Bacteroides dorei Reduce Gut Microbial Lipopolysaccharide Production and Inhibit Atherosclerosis

(2019) Naofumi Yoshida et al.   CIRCULATION

The Short-Chain Fatty Acid Propionate Protects from Hypertensive Cardiovascular Damage

(2019) Hendrik Bartolomaeus et al.   CIRCULATION

Loss of Gut Microbiota Alters Immune System Composition and Cripples Post-Infarction Cardiac Repair

(2019) Tony WH Tang et al.   CIRCULATION

Sex Differences in Coronary Artery and Thoracic Aorta Calcification and Their Association With Cardiovascular Mortality in Heavy Smokers

(2019) Nikolas Lessmann et al.   JACC-Cardiovascular Imaging

Function and mechanisms of enteroendocrine cells and gut hormones in metabolism

(2019) Fiona M. Gribble et al.   Nature Reviews Endocrinology

Causal relationships among the gut microbiome, short-chain fatty acids and metabolic diseases

(2019) Serena Sanna et al.   NATURE GENETICS

Intestinal Barrier Function–Non-alcoholic Fatty Liver Disease Interactions and Possible Role of Gut Microbiota

(2019) Yizhe Cui et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

The short-chain fatty acid propionate increases glucagon and FABP4 production, impairing insulin action in mice and humans

(2019) Amir Tirosh et al.   Science Translational Medicine

Potential roles of gut microbiome and metabolites in modulating ALS in mice

(2019) Eran Blacher et al.   NATURE

Reproducible, interactive, scalable and extensible microbiome data science using QIIME 2

(2019) Evan Bolyen et al.   NATURE BIOTECHNOLOGY

Supplementation with Akkermansia muciniphila in overweight and obese human volunteers: a proof-of-concept exploratory study

(2019) Clara Depommier et al.   NATURE MEDICINE

Healthspan and lifespan extension by fecal microbiota transplantation into progeroid mice

(2019) Clea Bárcena et al.   NATURE MEDICINE

Gut Microbiome Fermentation Determines the Efficacy of Exercise for Diabetes Prevention

(2019) Yan Liu et al.   Cell Metabolism

Anatomical References to Evaluate Thoracic Aorta Calcium by Computed Tomography

(2019) Jesiana Ferreira Pedrosa et al.   Current Atherosclerosis Reports

Establishment of Liquid Chromatography Retention Index Based on Chemical Labeling for Metabolomic Analysis

(2018) Shu-Jian Zheng et al.   ANALYTICAL CHEMISTRY

Comprehensive Profiling of Fecal Metabolome of Mice by Integrated Chemical Isotope Labeling-Mass Spectrometry Analysis

(2018) Bi-Feng Yuan et al.   ANALYTICAL CHEMISTRY

Deciphering the trophic interaction between Akkermansia muciniphila and the butyrogenic gut commensal Anaerostipes caccae using a metatranscriptomic approach

(2018) Loo Wee Chia et al.   ANTONIE VAN LEEUWENHOEK INTERNATIONAL JOURNAL OF GENERAL AND MOLECULAR MICROBIOLOGY

Role of smooth muscle cells in vascular calcification: implications in atherosclerosis and arterial stiffness

(2018) Andrew L Durham et al.   CARDIOVASCULAR RESEARCH

Pro- and anti-inflammatory effects of short chain fatty acids on immune and endothelial cells

(2018) Meng Li et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Gut bacteria selectively promoted by dietary fibers alleviate type 2 diabetes

(2018) Liping Zhao et al.   SCIENCE

A next generation probiotic, Akkermansia muciniphila

(2018) Qixiao Zhai et al.   CRITICAL REVIEWS IN FOOD SCIENCE AND NUTRITION

Interactions between Roseburia intestinalis and diet modulate atherogenesis in a murine model

(2018) Kazuyuki Kasahara et al.   Nature Microbiology

Recovery of ethanol-inducedAkkermansia muciniphiladepletion ameliorates alcoholic liver disease

(2017) Christoph Grander et al.   GUT

Structure-Specific Effects of Short-Chain Fatty Acids on Plasma Cholesterol Concentration in Male Syrian Hamsters

(2017) Yimin Zhao et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity

(2017) Valérie Turcot et al.   NATURE GENETICS

Microbial Metabolic Networks at the Mucus Layer Lead to Diet-Independent Butyrate and Vitamin B 12 Production by Intestinal Symbionts

(2017) Clara Belzer et al.   mBio

Next-Generation Beneficial Microbes: The Case of Akkermansia muciniphila

(2017) Patrice D. Cani et al.   Frontiers in Microbiology

Stable engraftment of human microbiota into mice with a single oral gavage following antibiotic conditioning

(2017) Christopher Staley et al.   Microbiome

High-Fiber Diet and Acetate Supplementation Change the Gut Microbiota and Prevent the Development of Hypertension and Heart Failure in Hypertensive MiceClinical Perspective

(2016) Francine Z. Marques et al.   CIRCULATION

Akkermansia MuciniphilaProtects Against Atherosclerosis by Preventing Metabolic Endotoxemia-Induced Inflammation inApoe−/−MiceCLINICAL PERSPECTIVE

(2016) Jin Li et al.   CIRCULATION

The diet-derived short chain fatty acid propionate improves beta-cell function in humans and stimulates insulin secretion from human islets in vitro

(2016) Attilio Pingitore et al.   DIABETES OBESITY & METABOLISM

Analysis of liposoluble carboxylic acids metabolome in human serum by stable isotope labeling coupled with liquid chromatography–mass spectrometry

(2016) Quan-Fei Zhu et al.   JOURNAL OF CHROMATOGRAPHY A

Akkermansia muciniphilaimproves metabolic profiles by reducing inflammation in chow diet-fed mice

(2016) Shaoqian Zhao et al.   JOURNAL OF MOLECULAR ENDOCRINOLOGY

A purified membrane protein from Akkermansia muciniphila or the pasteurized bacterium improves metabolism in obese and diabetic mice

(2016) Hubert Plovier et al.   NATURE MEDICINE

Microbial short chain fatty acid metabolites lower blood pressure via endothelial G protein-coupled receptor 41

(2016) Niranjana Natarajan et al.   PHYSIOLOGICAL GENOMICS

Bifidobacteria and Butyrate-Producing Colon Bacteria: Importance and Strategies for Their Stimulation in the Human Gut

(2016) Audrey Rivière et al.   Frontiers in Microbiology

Human and mouse monocytes display distinct signalling and cytokine profiles upon stimulation with FFAR2/FFAR3 short-chain fatty acid receptor agonists

(2016) Zhiwei Ang et al.   Scientific Reports

Short-Chain Fatty Acids Protect Against High-Fat Diet–Induced Obesity via a PPARγ-Dependent Switch From Lipogenesis to Fat Oxidation

(2015) Gijs den Besten et al.   DIABETES

Role of the Gut Microbiome in Obstructive Sleep Apnea–Induced Hypertension

(2015) David J. Durgan et al.   HYPERTENSION

Short-chain fatty acids in control of body weight and insulin sensitivity

(2015) Emanuel E. Canfora et al.   Nature Reviews Endocrinology

Vascular calcification: Mechanisms of vascular smooth muscle cell calcification

(2015) Jane A. Leopold   TRENDS IN CARDIOVASCULAR MEDICINE

Perspectives on the therapeutic potential of short-chain fatty acid receptors

(2014) Sunhong Kim et al.   BMB Reports

Intestinal permeability – a new target for disease prevention and therapy

(2014) Stephan C Bischoff et al.   BMC GASTROENTEROLOGY

Gut microbiota metabolism of dietary fiber influences allergic airway disease and hematopoiesis

(2014) Aurélien Trompette et al.   NATURE MEDICINE

Butyrate impairs atherogenesis by reducing plaque inflammation and vulnerability and decreasing NFκB activation

(2014) E.C. Aguilar et al.   NUTRITION METABOLISM AND CARDIOVASCULAR DISEASES

The short-chain fatty acid acetate reduces appetite via a central homeostatic mechanism

(2014) Gary Frost et al.   Nature Communications

First trimester fetal growth restriction and cardiovascular risk factors in school age children: population based cohort study

(2014) V. W. V. Jaddoe et al.   BMJ-British Medical Journal

G Protein-Coupled Receptor 43 Moderates Gut Inflammation Through Cytokine Regulation from Mononuclear Cells

(2013) Ryuta Masui et al.   INFLAMMATORY BOWEL DISEASES

Butyrate Attenuates Inflammation and Lipolysis Generated by the Interaction of Adipocytes and Macrophages

(2013) Hideo Ohira et al.   Journal of Atherosclerosis and Thrombosis

The role of short-chain fatty acids in the interplay between diet, gut microbiota, and host energy metabolism

(2013) Gijs den Besten et al.   JOURNAL OF LIPID RESEARCH

The many faces of diabetes: a disease with increasing heterogeneity

(2013) Tiinamaija Tuomi et al.   LANCET

Olfactory receptor responding to gut microbiota-derived signals plays a role in renin secretion and blood pressure regulation

(2013) Jennifer L. Pluznick et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Cross-talk between Akkermansia muciniphila and intestinal epithelium controls diet-induced obesity

(2013) A. Everard et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Fiber and Prebiotics: Mechanisms and Health Benefits

(2013) Joanne Slavin   Nutrients

Anti-Inflammatory Effects of Nicotinic Acid in Human Monocytes Are Mediated by GPR109A Dependent Mechanisms

(2012) Janet E. Digby et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Effects of a novel propionate-rich sourdough bread on appetite and food intake

(2012) J Darzi et al.   EUROPEAN JOURNAL OF CLINICAL NUTRITION

Prevalence of thoracic aortic calcification and its relationship to cardiovascular risk factors and coronary calcification in an unselected population-based cohort: the Heinz Nixdorf Recall Study

(2012) Hagen Kälsch et al.   INTERNATIONAL JOURNAL OF CARDIOVASCULAR IMAGING

FLASH: fast length adjustment of short reads to improve genome assemblies

(2011) T. Magoc et al.   BIOINFORMATICS

Linking Long-Term Dietary Patterns with Gut Microbial Enterotypes

(2011) G. D. Wu et al.   SCIENCE

Evaluation of Five Methods for Total DNA Extraction from Western Corn Rootworm Beetles

(2010) Hong Chen et al.   PLoS One

Tumor necrosis factor-α increases alkaline phosphatase expression in vascular smooth muscle cells via MSX2 induction

(2009) Hye-Lim Lee et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

The role of pH in determining the species composition of the human colonic microbiota

(2009) Sylvia H. Duncan et al.   ENVIRONMENTAL MICROBIOLOGY

Coronary Calcium as a Predictor of Coronary Events in Four Racial or Ethnic Groups

(2008) Robert Detrano et al.   NEW ENGLAND JOURNAL OF MEDICINE