Role of metalloproteases in the CD95 signaling pathways

The Death Receptor Pathway of Apoptosis

(2022) Douglas R. Green   Cold Spring Harbor Perspectives in Biology

Prognostic and Immunological Roles of MMP-9 in Pan-Cancer

(2022) Yudan Zeng et al.   Biomed Research International

Into the Tissues: Extracellular Matrix and Its Artificial Substitutes: Cell Signalling Mechanisms

(2022) Aleksandra Bandzerewicz et al.   Cells

Selective Inhibitors of Medium-Size S1′ Pocket Matrix Metalloproteinases: A Stepping Stone of Future Drug Discovery

(2022) Sandip Kumar Baidya et al.   JOURNAL OF MEDICINAL CHEMISTRY

Matrix Metalloproteinases: From Molecular Mechanisms to Physiology, Pathophysiology, and Pharmacology

(2022) Luiz G.N. de Almeida et al.   PHARMACOLOGICAL REVIEWS

MMP7 cleavage of amino-terminal CD95 death receptor switches signaling toward non-apoptotic pathways

(2022) Shoji F. Kenji et al.   Cell Death & Disease

Prognostic values of tumoral MMP2 and MMP9 overexpression in breast cancer: a systematic review and meta-analysis

(2021) Hanfang Jiang et al.   BMC CANCER

Contribution of ADAM17 and related ADAMs in cardiovascular diseases

(2021) Tatsuo Kawai et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Roles of matrix metalloproteinase-7 (MMP-7) in cancer

(2021) Hai-Yang Liao et al.   CLINICAL BIOCHEMISTRY

Sweet modification and regulation of death receptor signalling pathway

(2021) Kenta Moriwaki et al.   JOURNAL OF BIOCHEMISTRY

The paradoxical role of matrix metalloproteinase-11 in cancer

(2021) Bing Ma et al.   BIOMEDICINE & PHARMACOTHERAPY

The bioactivity of soluble Fas ligand is modulated by key amino acids of its stalk region

(2021) Osamu Kajikawa et al.   PLoS One

Soluble Fas ligand drives autoantibody-induced arthritis by binding to DR5/TRAIL-R2

(2021) Dongjin Jeong et al.   eLife

MMP2 and TLRs modulate immune responses in the tumor microenvironment

(2021) Luciana R. Muniz-Bongers et al.   JCI Insight

Soluble CD95L in cancers and chronic inflammatory disorders, a new therapeutic target?

(2021) Keerthi Kurma et al.   BIOCHIMICA ET BIOPHYSICA ACTA-REVIEWS ON CANCER

Meprin and ADAM proteases as triggers of systemic inflammation in sepsis

(2021) Sascha Rahn et al.   FEBS LETTERS

Review of cancer cell resistance mechanisms to apoptosis and actual targeted therapies

(2021) Merve Kulbay et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Safety and tolerability of asunercept plus standard radiotherapy/temozolomide in Asian patients with newly-diagnosed glioblastoma: a phase I study

(2021) Kuo-Chen Wei et al.   Scientific Reports

CD95/Fas protects triple negative breast cancer from anti-tumor activity of NK cells

(2021) Abdul S. Qadir et al.   iScience

CD95/Fas suppresses NF-κB activation through recruitment of KPC2 in a CD95L/FasL-independent mechanism

(2021) Jean-Philippe Guégan et al.   iScience

Ectodomain shedding by ADAM proteases as a central regulator in kidney physiology and disease

(2021) Catherine Meyer-Schwesinger et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Matrix Metalloproteinases Retain Soluble FasL-mediated Resistance to Cell Death in Fibrotic-Lung Myofibroblasts

(2020) David Nareznoi et al.   Cells

Knockout of MMP3 Weakens Solid Tumor Organoids and Cancer Extracellular Vesicles

(2020) Eman Taha et al.   Cancers

CD95 Structure, Aggregation and Cell Signaling

(2020) Nicolas Levoin et al.   Frontiers in Cell and Developmental Biology

Exploring Sodium Glucose Co-Transporter-2 (SGLT2) Inhibitors for Organ Protection in COVID-19

(2020) Beatriz Fernandez-Fernandez et al.   Journal of Clinical Medicine

Clinical Response to the CD95-Ligand Inhibitor Asunercept Is Defined by a Pro-Inflammatory Serum Cytokine Profile

(2020) Aleksandar Radujkovic et al.   Cancers

MT4-MMP: The GPI-Anchored Membrane-Type Matrix Metalloprotease with Multiple Functions in Diseases

(2019) Cassandre Yip et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Metalloproteinases TACE and MMP-9 Differentially Regulate Death Factors on Adult and Neonatal Monocytes After Infection with Escherichia coli

(2019) Stephan Dreschers et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Design and Structural Evolution of Matrix Metalloproteinase Inhibitors

(2019) Thomas Fischer et al.   CHEMISTRY-A EUROPEAN JOURNAL

CD95/Fas and metastatic disease: What does not kill you makes you stronger

(2019) Jean Philippe Guégan et al.   SEMINARS IN CANCER BIOLOGY

The Rebirth of Matrix Metalloproteinase Inhibitors: Moving Beyond the Dogma

(2019) Gregg B. Fields   Cells

Matrix Metalloproteinase-9 (MMP-9) as a Cancer Biomarker and MMP-9 Biosensors: Recent Advances

(2018) Hao Huang   SENSORS

Disrupting the CD95–PLCγ1 interaction prevents Th17-driven inflammation

(2018) Amanda Poissonnier et al.   Nature Chemical Biology

Fas activation alters tight junction proteins in acute lung injury

(2018) Raquel Herrero et al.   THORAX

Metalloproteinases in atherosclerosis

(2017) Jason L. Johnson   EUROPEAN JOURNAL OF PHARMACOLOGY

Nonapoptotic functions of Fas/CD95 in the immune response

(2017) Jean-Philippe Guégan et al.   FEBS Journal

The ADAMs family of proteases as targets for the treatment of cancer

(2016) Maeve Mullooly et al.   CANCER BIOLOGY & THERAPY

CD95-Mediated Calcium Signaling Promotes T Helper 17 Trafficking to Inflamed Organs in Lupus-Prone Mice

(2016) Amanda Poissonnier et al.   IMMUNITY

Zinc–Metalloproteinase Inhibitors: Evaluation of the Complex Role Played by the Zinc-Binding Group on Potency and Selectivity

(2016) Cecile Rouanet-Mehouas et al.   JOURNAL OF MEDICINAL CHEMISTRY

Crystal Structure of the Complex of Human FasL and Its Decoy Receptor DcR3

(2016) Weifeng Liu et al.   STRUCTURE

The Janus Face of Death Receptor Signaling during Tumor Immunoediting

(2016) Eimear O’ Reilly et al.   Frontiers in Immunology

The crystal structure of DR6 in complex with the amyloid precursor protein provides insight into death receptor activation

(2015) Kai Xu et al.   GENES & DEVELOPMENT

Elevated STAT3 Signaling-Mediated Upregulation of MMP-2/9 Confers Enhanced Invasion Ability in Multidrug-Resistant Breast Cancer Cells

(2015) Fei Zhang et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Subcellular localization and activation of ADAM proteases in the context of FasL shedding in T lymphocytes

(2015) Henriette Ebsen et al.   MOLECULAR IMMUNOLOGY

New approaches to selectively target cancer-associated matrix metalloproteinase activity

(2014) Marilena Tauro et al.   CANCER AND METASTASIS REVIEWS

A Phase II, Randomized, Study of Weekly APG101+Reirradiation versus Reirradiation in Progressive Glioblastoma

(2014) W. Wick et al.   CLINICAL CANCER RESEARCH

CD95L Cell Surface Cleavage Triggers a Prometastatic Signaling Pathway in Triple-Negative Breast Cancer

(2013) M. Malleter et al.   CANCER RESEARCH

Functional Characterization of a Chimeric Soluble Fas Ligand Polymer with In Vivo Anti-Tumor Activity

(2013) Sophie Daburon et al.   PLoS One

Missing the target: matrix metalloproteinase antitargets in inflammation and cancer

(2013) Antoine Dufour et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

CD95 signaling in colorectal cancer

(2012) Frederik J.H. Hoogwater et al.   BIOCHIMICA ET BIOPHYSICA ACTA-REVIEWS ON CANCER

Matrix Metalloproteinase-13 (MMP-13) Directly and Indirectly Promotes Tumor Angiogenesis

(2012) Yasusei Kudo et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Precise Mapping of the CD95 Pre-Ligand Assembly Domain

(2012) Valérie Edmond et al.   PLoS One

The extracellular matrix: an active or passive player in fibrosis?

(2011) Thomas N. Wight et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

How CD95 stimulates invasion

(2011) Ernst J.A. Steller et al.   CELL CYCLE

CD95-mediated cell signaling in cancer: mutations and post-translational modulations

(2011) Sébastien Tauzin et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

The biological activity of FasL in human and mouse lungs is determined by the structure of its stalk region

(2011) Raquel Herrero et al.   JOURNAL OF CLINICAL INVESTIGATION

The Naturally Processed CD95L Elicits a c-Yes/Calcium/PI3K-Driven Cell Migration Pathway

(2011) Sébastien Tauzin et al.   PLOS BIOLOGY

Third generation of matrix metalloprotease inhibitors: Gain in selectivity by targeting the depth of the S1′ cavity

(2010) Laurent Devel et al.   BIOCHIMIE

Immune modulation by Fas ligand reverse signaling: lymphocyte proliferation is attenuated by the intracellular Fas ligand domain

(2010) K. Luckerath et al.   BLOOD

Matrix Metalloproteinases: Regulators of the Tumor Microenvironment

(2010) Kai Kessenbrock et al.   CELL

Oncogenic K-Ras Turns Death Receptors Into Metastasis-Promoting Receptors in Human and Mouse Colorectal Cancer Cells

(2010) Frederik J.H. Hoogwater et al.   GASTROENTEROLOGY

CD95-Ligand on Peripheral Myeloid Cells Activates Syk Kinase to Trigger Their Recruitment to the Inflammatory Site

(2010) Elisabeth Letellier et al.   IMMUNITY

ADAM 10 is associated with gastric cancer progression and prognosis of patients

(2010) Yuan-Yu Wang et al.   JOURNAL OF SURGICAL ONCOLOGY

CD95 promotes tumour growth

(2010) Lina Chen et al.   NATURE

Membrane-bound Fas ligand only is essential for Fas-induced apoptosis

(2009) Lorraine A. O’ Reilly et al.   NATURE

APP binds DR6 to trigger axon pruning and neuron death via distinct caspases

(2009) Anatoly Nikolaev et al.   NATURE

The Role of MMP7 and Its Cross-Talk with the FAS/FASL System during the Acquisition of Chemoresistance to Oxaliplatin

(2009) Vanessa Almendro et al.   PLoS One

Plasminogen Activator Inhibitor-1 Protects Endothelial Cells from FasL-Mediated Apoptosis

(2008) Khalid Bajou et al.   CANCER CELL

Yes and PI3K Bind CD95 to Signal Invasion of Glioblastoma

(2008) Susanne Kleber et al.   CANCER CELL

Prevention of Autoimmunity and Control of Recall Response to Exogenous Antigen by Fas Death Receptor Ligand Expression on T Cells

(2008) Imed Mabrouk et al.   IMMUNITY

The ADAM metalloproteinases

(2008) D EDWARDS et al.   MOLECULAR ASPECTS OF MEDICINE

A Novel Juxtamembrane Domain in Tumor Necrosis Factor Receptor Superfamily Molecules Activates Rac1 and Controls Neurite Growth

(2008) Wenjing Ruan et al.   MOLECULAR BIOLOGY OF THE CELL