New approaches to selectively target cancer-associated matrix metalloproteinase activity

Paclitaxel: biosynthesis, production and future prospects

(2014) Susan Howat et al.   New Biotechnology

Trial Watch

(2014) Erika Vacchelli et al.   OncoImmunology

Arylamino methylene bisphosphonate derivatives as bone seeking matrix metalloproteinase inhibitors

(2013) Marilena Tauro et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Role of L1 cell adhesion molecule (L1CAM) in the metastatic cascade: promotion of dissemination, colonization, and metastatic growth

(2013) Dirk Weinspach et al.   CLINICAL & EXPERIMENTAL METASTASIS

The hemopexin domain of MMP3 is responsible for mammary epithelial invasion and morphogenesis through extracellular interaction with HSP90 

(2013) A. L. Correia et al.   GENES & DEVELOPMENT

Non-destructive and Selective Imaging of the Functionally Active, Pro-invasive Membrane Type-1 Matrix Metalloproteinase (MT1-MMP) Enzyme in Cancer Cells

(2013) Albert G. Remacle et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

O-Phenyl Carbamate and Phenyl Urea Thiiranes as Selective Matrix Metalloproteinase-2 Inhibitors that Cross the Blood–Brain Barrier

(2013) Major Gooyit et al.   JOURNAL OF MEDICINAL CHEMISTRY

Coupling Protein Engineering with Probe Design To Inhibit and Image Matrix Metalloproteinases with Controlled Specificity

(2013) Montse Morell et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Synthesis and In Vitro Efficacy of MMP9-Activated NanoDendrons

(2013) Lynn E. Samuelson et al.   MOLECULAR PHARMACEUTICS

Quantitative imaging of disease signatures through radioactive decay signal conversion

(2013) Daniel L J Thorek et al.   NATURE MEDICINE

Intelligently Targeted Drug Delivery and Enhanced Antitumor Effect by Gelatinase-Responsive Nanoparticles

(2013) Rutian Li et al.   PLoS One

Development of Novel Tumor-Targeted Theranostic Nanoparticles Activated by Membrane-Type Matrix Metalloproteinases for Combined Cancer Magnetic Resonance Imaging and Therapy

(2013) Celina Ansari et al.   Small

A monoclonal antibody interferes with TIMP-2 binding and incapacitates the MMP-2-activating function of multifunctional, pro-tumorigenic MMP-14/MT1–MMP

(2013) S A Shiryaev et al.   Oncogenesis

Development of a Neutralizing Antibody Specific for the Active Form of Matrix Metalloproteinase-13

(2012) Shoichi Naito et al.   BIOCHEMISTRY

Detection of MMP-2 and MMP-9 Activity in Vivo with a Triple-Helical Peptide Optical Probe

(2012) Walter J. Akers et al.   BIOCONJUGATE CHEMISTRY

PEG-co-PCL nanoparticles modified with MMP-2/9 activatable low molecular weight protamine for enhanced targeted glioblastoma therapy

(2012) Guangzhi Gu et al.   BIOMATERIALS

Bevacizumab: overview of the literature

(2012) Maria Ignez Braghiroli et al.   Expert Review of Anticancer Therapy

Extra- and Intracellular Imaging of Human Matrix Metalloprotease 11 (hMMP-11) with a Cell-penetrating FRET Substrate

(2012) B. Sina Meyer et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

News & Views in ... Nanomedicine

(2012)   Nanomedicine

New approaches for dissecting protease functions to improve probe development and drug discovery

(2012) Edgar Deu et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Antiphotoaging effect of chitooligosaccharides on human dermal fibroblasts

(2012) Jung-Ae Kim et al.   PHOTODERMATOLOGY PHOTOIMMUNOLOGY & PHOTOMEDICINE

An Osteoblast-Derived Proteinase Controls Tumor Cell Survival via TGF-beta Activation in the Bone Microenvironment

(2012) Sophie Thiolloy et al.   PLoS One

Directed Evolution of Protease Beacons that Enable Sensitive Detection of Endogenous MT1-MMP Activity in Tumor Cell Lines

(2011) Abeer Jabaiah et al.   CHEMISTRY & BIOLOGY

Biphenyl Sulfonylamino Methyl Bisphosphonic Acids as Inhibitors of Matrix Metalloproteinases and Bone Resorption

(2011) Maria Teresa Rubino et al.   ChemMedChem

Trastuzumab Emtansine (T-DM1): A Novel Agent for Targeting HER2+ Breast Cancer

(2011) Howard A. Burris et al.   Clinical Breast Cancer

A One-Pot Synthesis and Biological Activity of Ageladine A and Analogues

(2011) Sudhir R. Shengule et al.   JOURNAL OF MEDICINAL CHEMISTRY

Antibodies targeting the catalytic zinc complex of activated matrix metalloproteinases show therapeutic potential

(2011) Netta Sela-Passwell et al.   NATURE MEDICINE

Third generation of matrix metalloprotease inhibitors: Gain in selectivity by targeting the depth of the S1′ cavity

(2010) Laurent Devel et al.   BIOCHIMIE

Selective matrix metalloproteinase (MMP) inhibitors in cancer therapy: Ready for prime time?

(2010) Stanley Zucker et al.   CANCER BIOLOGY & THERAPY

Peptides and Peptide Hormones for Molecular Imaging and Disease Diagnosis

(2010) Seulki Lee et al.   CHEMICAL REVIEWS

MT1-MMP Is Required for Myeloid Cell Fusion via Regulation of Rac1 Signaling

(2010) Pilar Gonzalo et al.   DEVELOPMENTAL CELL

To exploit the tumor microenvironment: Passive and active tumor targeting of nanocarriers for anti-cancer drug delivery

(2010) Fabienne Danhier et al.   JOURNAL OF CONTROLLED RELEASE

Chemoradiotherapy With or Without AE-941 in Stage III Non–Small Cell Lung Cancer: A Randomized Phase III Trial

(2010) Charles Lu et al.   JNCI-Journal of the National Cancer Institute

Using tetracyclines to treat osteoporotic/osteopenic bone loss: From the basic science laboratory to the clinic

(2010) Jeffrey B. Payne et al.   PHARMACOLOGICAL RESEARCH

Activatable cell penetrating peptides linked to nanoparticles as dual probes for in vivo fluorescence and MR imaging of proteases

(2010) E. S. Olson et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Chemistry and Biochemistry of Dietary Polyphenols

(2010) Rong Tsao   Nutrients

Matrix metalloproteinases: What do they not do? New substrates and biological roles identified by murine models and proteomics

(2009) David Rodríguez et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Selective Inhibition of Matrix Metalloproteinase-14 Blocks Tumor Growth, Invasion, and Angiogenesis

(2009) Laetitia Devy et al.   CANCER RESEARCH

Bioluminescent nanosensors for protease detection based upon gold nanoparticle–luciferase conjugates

(2009) Young-Pil Kim et al.   CHEMICAL COMMUNICATIONS

Matrix Metalloproteinases As Novel Biomarker s and Potential Therapeutic Targets in Human Cancer

(2009) Roopali Roy et al.   JOURNAL OF CLINICAL ONCOLOGY

Inflammatory and alternatively activated human macrophages attract vessel-associated stem cells, relying on separate HMGB1- and MMP-9-dependent pathways

(2009) Karine Lolmede et al.   JOURNAL OF LEUKOCYTE BIOLOGY

DFT Studies of the Ring-Opening Mechanism of SB-3CT, a Potent Inhibitor of Matrix Metalloproteinase 2

(2009) Peng Tao et al.   ORGANIC LETTERS

Induction of a MT1-MMP and MT2-MMP-dependent basement membrane transmigration program in cancer cells by Snail1

(2009) I. Ota et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Imaging matrix metalloproteinases in cancer

(2008) Randy L. Scherer et al.   CANCER AND METASTASIS REVIEWS

Green Tea Catechins and Cardiovascular Health: An Update

(2008) Pon Anandh Babu et al.   CURRENT MEDICINAL CHEMISTRY

In Situ “Click” Assembly of Small Molecule Matrix Metalloprotease Inhibitors Containing Zinc-Chelating Groups

(2008) Mingyu Hu et al.   ORGANIC LETTERS