Elevated STAT3 Signaling-Mediated Upregulation of MMP-2/9 Confers Enhanced Invasion Ability in Multidrug-Resistant Breast Cancer Cells

RNAi-mediated silencing of Anxa2 inhibits breast cancer cell proliferation by downregulating cyclin D1 in STAT3-dependent pathway

(2015) Fei Zhang et al.   BREAST CANCER RESEARCH AND TREATMENT

Establishment and characterization of gemcitabine-resistant human cholangiocarcinoma cell lines with multidrug resistance and enhanced invasiveness

(2015) WAREEPORN WATTANAWONGDON et al.   INTERNATIONAL JOURNAL OF ONCOLOGY

A novel Anxa2-interacting protein Ebp1 inhibits cancer proliferation and invasion by suppressing Anxa2 protein level

(2015) Fei Zhang et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Clinical overview of metronomic chemotherapy in breast cancer

(2015) Elisabetta Munzone et al.   Nature Reviews Clinical Oncology

Challenges in the management of advanced, ER-positive, HER2-negative breast cancer

(2015) Christopher D. Hart et al.   Nature Reviews Clinical Oncology

MDR1 and ERCC1 Expression Predict Outcome of Patients with Locally Advanced Bladder Cancer Receiving Adjuvant Chemotherapy

(2015) Andreas-Claudius Hoffmann et al.   NEOPLASIA

Activating transcription factor 4 mediates a multidrug resistance phenotype of esophageal squamous cell carcinoma cells through transactivation of STAT3 expression

(2014) Hongwu Zhu et al.   CANCER LETTERS

Multi-drug resistance in cancer chemotherapeutics: Mechanisms and lab approaches

(2014) Qiong Wu et al.   CANCER LETTERS

ABC Transporters in Multidrug Resistance and Pharmacokinetics, and Strategies for Drug Development

(2014) Young Choi et al.   CURRENT PHARMACEUTICAL DESIGN

Drug Resistance in Cancer: An Overview

(2014) Genevieve Housman et al.   Cancers

P-glycoprotein-dependent resistance of cancer cells toward the extrinsic TRAIL apoptosis signaling pathway

(2013) Hanan Galski et al.   BIOCHEMICAL PHARMACOLOGY

P-glycoprotein associates with Anxa2 and promotes invasion in multidrug resistant breast cancer cells

(2013) Fei Zhang et al.   BIOCHEMICAL PHARMACOLOGY

Critical Role of STAT3 in IL-6–Mediated Drug Resistance in Human Neuroblastoma

(2013) Tasnim Ara et al.   CANCER RESEARCH

Epithelial-to-mesenchymal transition: What is the impact on breast cancer stem cells and drug resistance

(2013) Paraskevi Mallini et al.   CANCER TREATMENT REVIEWS

Chemotherapeutic agents enhance cell migration and epithelial-to-mesenchymal transition through transient up-regulation of tNOX (ENOX2) protein

(2012) Yu-Ching Su et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Galectin-1 Promotes Lung Cancer Progression and Chemoresistance by Upregulating p38 MAPK, ERK, and Cyclooxygenase-2

(2012) L.-Y. Chung et al.   CLINICAL CANCER RESEARCH

An Epithelial-Mesenchymal Transition Gene Signature Predicts Resistance to EGFR and PI3K Inhibitors and Identifies Axl as a Therapeutic Target for Overcoming EGFR Inhibitor Resistance

(2012) L. A. Byers et al.   CLINICAL CANCER RESEARCH

MDR1-P-glycoprotein behaves as an oncofetal protein that promotes cell survival in gastric cancer cells

(2012) Alba Rocco et al.   LABORATORY INVESTIGATION

Global cancer statistics

(2011) Ahmedin Jemal et al.   CA-A CANCER JOURNAL FOR CLINICIANS

Inhibition of activated Stat3 reverses drug resistance to chemotherapeutic agents in gastric cancer cells

(2011) Shuling Huang et al.   CANCER LETTERS

Involvement of EGFR in the promotion of malignant properties in multidrug resistant breast cancer cells

(2011) Zu-De Xu   INTERNATIONAL JOURNAL OF ONCOLOGY

The Emergence of Drug Transporter-Mediated Multidrug Resistance to Cancer Chemotherapy

(2011) Chung-Pu Wu et al.   MOLECULAR PHARMACEUTICS

Multidrug Resistance Gene (MDR-1) and Risk of Brain Metastasis in Epithelial Ovarian, Fallopian Tube, and Peritoneal Cancer

(2010) Koji Matsuo et al.   AMERICAN JOURNAL OF CLINICAL ONCOLOGY-CANCER CLINICAL TRIALS

Drug resistant MCF-7 cells exhibit epithelial-mesenchymal transition gene expression pattern

(2010) Özlem Darcansoy Işeri et al.   BIOMEDICINE & PHARMACOTHERAPY

Co-expression of CD147 (EMMPRIN), CD44v3-10, MDR1 and monocarboxylate transporters is associated with prostate cancer drug resistance and progression

(2010) J Hao et al.   BRITISH JOURNAL OF CANCER

Matrix metalloproteinase-9 is required for tubular network formation and migration of resistant breast cancer cells MCF-7 through PKC and ERK1/2 signalling pathways

(2010) Asmae Karroum et al.   CANCER LETTERS

Protein Kinase C Isoforms ζ and ι Mediate Collagenase Expression and Cartilage Destruction via STAT3- and ERK-dependent c-fosInduction

(2010) Gary J. Litherland et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

MDR1/P-gp and VEGF Synergistically Enhance the Invasion of Hep-2 Cells with Multidrug Resistance Induced by Taxol

(2009) Li Li et al.   ANNALS OF SURGICAL ONCOLOGY

Coexpression of invasive markers (uPA, CD44) and multiple drug-resistance proteins (MDR1, MRP2) is correlated with epithelial ovarian cancer progression

(2009) H Chen et al.   BRITISH JOURNAL OF CANCER

EGF-induced MMP-9 expression is mediated by the JAK3/ERK pathway, but not by the JAK3/STAT-3 pathway in a SKBR3 breast cancer cell line

(2009) Sangmin Kim et al.   CELLULAR SIGNALLING

Twist1-Mediated Adriamycin-Induced Epithelial-Mesenchymal Transition Relates to Multidrug Resistance and Invasive Potential in Breast Cancer Cells

(2009) Q.-Q. Li et al.   CLINICAL CANCER RESEARCH

Akt promotes chemoresistance in human ovarian cancer cells by modulating cisplatin-induced, p53-dependent ubiquitination of FLICE-like inhibitory protein

(2009) M R Abedini et al.   ONCOGENE

Doxorubicin activates FOXO3a to induce the expression of multidrug resistance gene ABCB1 (MDR1) in K562 leukemic cells

(2008) R. C-Y. Hui et al.   MOLECULAR CANCER THERAPEUTICS

The Multidrug Transporter P-Glycoprotein: A Mediator of Melanoma Invasion?

(2007) Marisa Colone et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY