Physical exercise mediates a cortical FMRP–mTOR pathway to improve resilience against chronic stress in adolescent mice

Physical Exercise Prevented Stress‐Induced Anxiety via Improving Brain RNA Methylation

(2022) Lan Yan et al.   Advanced Science

The molecular biology of FMRP: new insights into fragile X syndrome

(2021) Joel D. Richter et al.   NATURE REVIEWS NEUROSCIENCE

Antioxidant treatment ameliorates prefrontal hypomyelination and cognitive deficits in a rat model of schizophrenia

(2021) D. A. Maas et al.   NEUROPSYCHOPHARMACOLOGY

Single-cell transcriptomic reveals molecular diversity and developmental heterogeneity of human stem cell-derived oligodendrocyte lineage cells

(2021) Xitiz Chamling et al.   Nature Communications

Chronic mild stress-induced protein dysregulations correlated with susceptibility and resiliency to depression or anxiety revealed by quantitative proteomics of the rat prefrontal cortex

(2021) Wei Liao et al.   Translational Psychiatry

Adenosine A2A receptor inhibition reduces synaptic and cognitive hippocampal alterations in Fmr1 KO mice

(2021) Antonella Ferrante et al.   Translational Psychiatry

Fmrp regulates oligodendrocyte lineage cell specification and differentiation

(2021) Caleb A. Doll et al.   GLIA

mTOR Signaling Regulates Metabolic Function in Oligodendrocyte Precursor Cells and Promotes Efficient Brain Remyelination in the Cuprizone Model

(2021) Marisa A. Jeffries et al.   JOURNAL OF NEUROSCIENCE

Swimming exercise attenuates anxiety-like behavior by reducing brain oxidative stress in type 2 diabetic mice

(2021) Parinaz Matinfar et al.   PHYSIOLOGY & BEHAVIOR

Microglia-neuron interaction at nodes of Ranvier depends on neuronal activity through potassium release and contributes to remyelination

(2021) R. Ronzano et al.   Nature Communications

Effects of Voluntary Running Wheel Exercise-Induced Extracellular Vesicles on Anxiety

(2021) Kyeong Jin Yoon et al.   Frontiers in Molecular Neuroscience

The Impact of Voluntary Exercise on Stroke Recovery

(2021) Klara J. Lohkamp et al.   Frontiers in Neuroscience

Physical exercise rescues cocaine-evoked synaptic deficits in motor cortex

(2021) Tong Cheng et al.   MOLECULAR PSYCHIATRY

A metabolome atlas of the aging mouse brain

(2021) Jun Ding et al.   Nature Communications

Exercise rather than fluoxetine promotes oligodendrocyte differentiation and myelination in the hippocampus in a male mouse model of depression

(2021) Jing Tang et al.   Translational Psychiatry

Central Suppression of the GH/IGF Axis and Abrogation of Exercise-Related mTORC1/2 Activation in the Muscle of Phenotype-Selected Male Marathon Mice (DUhTP)

(2021) Julia Brenmoehl et al.   Cells

Microglia, Lifestyle Stress, and Neurodegeneration

(2020) Charlotte Madore et al.   IMMUNITY

Exercise modulates the levels of growth inhibitor genes before and after multiple sclerosis

(2020) Seyed Houtan Shahidi et al.   JOURNAL OF NEUROIMMUNOLOGY

Physical exercise promotes astrocyte coverage of microvessels in a model of chronic cerebral hypoperfusion

(2020) Marina Leardini-Tristão et al.   Journal of Neuroinflammation

Identification of a prefrontal cortex-to-amygdala pathway for chronic stress-induced anxiety

(2020) Wei-Zhu Liu et al.   Nature Communications

Interneuron hypomyelination is associated with cognitive inflexibility in a rat model of schizophrenia

(2020) Dorien A. Maas et al.   Nature Communications

Advances in physical rehabilitation of multiple sclerosis

(2020) Diego Centonze et al.   CURRENT OPINION IN NEUROLOGY

Blood factors transfer beneficial effects of exercise on neurogenesis and cognition to the aged brain

(2020) Alana M. Horowitz et al.   SCIENCE

Astrocyte remodeling in the beneficial effects of long-term voluntary exercise in Alzheimer’s disease

(2020) Irina Belaya et al.   Journal of Neuroinflammation

Aerobic exercise training decreases cognitive impairment caused by demyelination by regulating ROCK signaling pathway in aging mice

(2020) Chuncha Bao et al.   BRAIN RESEARCH BULLETIN

Mechanisms of Aerobic Exercise Upregulating the Expression of Hippocampal Synaptic Plasticity-Associated Proteins in Diabetic Rats

(2019) Jingjing Li et al.   NEURAL PLASTICITY

Exercise prevents obesity-induced cognitive decline and white matter damage in mice

(2019) Leah C. Graham et al.   NEUROBIOLOGY OF AGING

Exercise training improves motor skill learning via selective activation of mTOR

(2019) Kai Chen et al.   Science Advances

Early-life stress impairs postnatal oligodendrogenesis and adult emotional behaviour through activity-dependent mechanisms

(2019) Anne Teissier et al.   MOLECULAR PSYCHIATRY

Region-specific myelin differences define behavioral consequences of chronic social defeat stress in mice

(2019) Valentina Bonnefil et al.   eLife

Voluntary wheel running promotes myelination in the motor cortex through Wnt signaling in mice

(2019) Jian Zheng et al.   Molecular Brain

Neuroplasticity in cognitive and psychological mechanisms of depression: an integrative model

(2019) Rebecca B. Price et al.   MOLECULAR PSYCHIATRY

Rescue of Fragile X Syndrome Neurons by DNA Methylation Editing of the FMR1 Gene

(2018) X. Shawn Liu et al.   CELL

Activity-Dependent Myelination of Parvalbumin Interneurons Mediated by Axonal Morphological Plasticity

(2018) Jeffrey Stedehouder et al.   JOURNAL OF NEUROSCIENCE

Multimodal Enhancement of Remyelination by Exercise with a Pivotal Role for Oligodendroglial PGC1α

(2018) Samuel K. Jensen et al.   Cell Reports

Gallic acid activates hippocampal BDNF-Akt-mTOR signaling in chronic mild stress

(2018) Ji-Xiao Zhu et al.   METABOLIC BRAIN DISEASE

Metformin ameliorates core deficits in a mouse model of fragile X syndrome

(2017) Ilse Gantois et al.   NATURE MEDICINE

mTORC1 promotes proliferation of immature Schwann cells and myelin growth of differentiated Schwann cells

(2017) Bogdan Beirowski et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

An examination of the anxiolytic effects of exercise for people with anxiety and stress-related disorders: A meta-analysis

(2017) Brendon Stubbs et al.   PSYCHIATRY RESEARCH

Brain-Derived Neurotrophic Factor, Depression, and Physical Activity: Making the Neuroplastic Connection

(2017) Cristy Phillips   NEURAL PLASTICITY

Treadmill exercise suppressed stress-induced dendritic spine elimination in mouse barrel cortex and improved working memory via BDNF/TrkB pathway

(2017) K Chen et al.   Translational Psychiatry

Resistance exercise initiates mechanistic target of rapamycin (mTOR) translocation and protein complex co-localisation in human skeletal muscle

(2017) Zhe Song et al.   Scientific Reports

Chronic stress regulates NG2 + cell maturation and myelination in the prefrontal cortex through induction of death receptor 6

(2016) Youjun Yang et al.   EXPERIMENTAL NEUROLOGY

Activity-Dependent and Experience-Driven Myelination Provide New Directions for the Management of Multiple Sclerosis

(2016) Samuel K. Jensen et al.   TRENDS IN NEUROSCIENCES

Voluntary exercise and increased food intake after mild chronic stress improve social avoidance behavior in mice

(2015) Airi Otsuka et al.   PHYSIOLOGY & BEHAVIOR

Conditional Ablation of Raptor or Rictor Has Differential Impact on Oligodendrocyte Differentiation and CNS Myelination

(2014) K. K. Bercury et al.   JOURNAL OF NEUROSCIENCE

Neuronal Activity Promotes Oligodendrogenesis and Adaptive Myelination in the Mammalian Brain

(2014) E. M. Gibson et al.   SCIENCE

Delayed myelination in a mouse model of fragile X syndrome

(2013) L. K. K. Pacey et al.   HUMAN MOLECULAR GENETICS

Neuroplasticity in the context of motor rehabilitation after stroke

(2011) Michael A. Dimyan et al.   Nature Reviews Neurology

Dysregulation of mTOR Signaling in Fragile X Syndrome

(2010) A. Sharma et al.   JOURNAL OF NEUROSCIENCE

Activation of the Mammalian Target of Rapamycin (mTOR) Is Essential for Oligodendrocyte Differentiation

(2009) W. A. Tyler et al.   JOURNAL OF NEUROSCIENCE