Astrocyte remodeling in the beneficial effects of long-term voluntary exercise in Alzheimer’s disease

Voluntary running does not reduce neuroinflammation or improve non-cognitive behavior in the 5xFAD mouse model of Alzheimer’s disease

(2020) Martina Svensson et al.   Scientific Reports

The relationship between the morphological subtypes of microglia and Alzheimer’s disease neuropathology

(2019) Patrick Jarmo Paasila et al.   BRAIN PATHOLOGY

Single-cell transcriptomic analysis of Alzheimer’s disease

(2019) Hansruedi Mathys et al.   NATURE

Exercise induces region‐specific remodeling of astrocyte morphology and reactive astrocyte gene expression patterns in male mice

(2019) Adam J. Lundquist et al.   JOURNAL OF NEUROSCIENCE RESEARCH

Effects of physical activity and exercise on the cognitive function of patients with Alzheimer disease: a meta-analysis

(2019) Rui-xia Jia et al.   BMC Geriatrics

Astroglial atrophy in Alzheimer’s disease

(2019) Alexei Verkhratsky et al.   PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY

Neuroinflammation as a Common Feature of Neurodegenerative Disorders

(2019) Leonardo Guzman-Martinez et al.   Frontiers in Pharmacology

A single-cell atlas of entorhinal cortex from individuals with Alzheimer’s disease reveals cell-type-specific gene expression regulation

(2019) Alexandra Grubman et al.   NATURE NEUROSCIENCE

Human astrocytes in the diseased brain

(2018) Elena Dossi et al.   BRAIN RESEARCH BULLETIN

BDNF effects on dendritic spine morphology and hippocampal function

(2018) Oliver von Bohlen und Halbach et al.   CELL AND TISSUE RESEARCH

Long-term treadmill exercise attenuates Aβ burdens and astrocyte activation in APP/PS1 mouse model of Alzheimer’s disease

(2018) Jing Zhang et al.   NEUROSCIENCE LETTERS

Weight Loss and Malnutrition in Patients with Parkinson's Disease: Current Knowledge and Future Prospects

(2018) Kai Ma et al.   Frontiers in Aging Neuroscience

Physical Exercise Protects Against Alzheimer's Disease in 3xTg-AD Mice

(2018) Yoelvis García-Mesa et al.   JOURNAL OF ALZHEIMERS DISEASE

Tetrahydrohyperforin Increases Adult Hippocampal Neurogenesis in Wild-Type and APPswe/PS1ΔE9 Mice

(2018) Ana C. Abbott et al.   JOURNAL OF ALZHEIMERS DISEASE

Impaired Hippocampal Neurogenesis and its Enhancement with Ghrelin in 5XFAD Mice

(2018) Minho Moon et al.   JOURNAL OF ALZHEIMERS DISEASE

Combined adult neurogenesis and BDNF mimic exercise effects on cognition in an Alzheimer’s mouse model

(2018) Se Hoon Choi et al.   SCIENCE

Neuroprotective effects of exercise in rodent models of memory deficit and Alzheimer's

(2018) Zahra Jahangiri et al.   METABOLIC BRAIN DISEASE

Astrocyte and Alzheimer’s disease

(2017) Zhiyou Cai et al.   JOURNAL OF NEUROLOGY

Running Changes the Brain: the Long and the Short of It

(2017) Carmen Vivar et al.   PHYSIOLOGY

Physical exercise induces structural alterations in the hippocampal astrocytes: exploring the role of BDNF-TrkB signaling

(2016) Atoossa Fahimi et al.   Brain Structure & Function

The Cellular Phase of Alzheimer’s Disease

(2016) Bart De Strooper et al.   CELL

Limited Effects of Prolonged Environmental Enrichment on the Pathology of 5XFAD Mice

(2016) Melanie Hüttenrauch et al.   MOLECULAR NEUROBIOLOGY

Fingolimod modulates multiple neuroinflammatory markers in a mouse model of Alzheimer’s disease

(2016) Nurgul Aytan et al.   Scientific Reports

Astrocytes: a central element in neurological diseases

(2015) Milos Pekny et al.   ACTA NEUROPATHOLOGICA

Long-term treadmill exercise improves spatial memory of male appswe/ps1de9 mice by regulation of bdnf expression and microglia activation

(2015) Jingyu Xiong et al.   BIOLOGY OF SPORT

Voluntary Running Attenuates Memory Loss, Decreases Neuropathological Changes and Induces Neurogenesis in a Mouse Model of Alzheimer's Disease

(2015) Cheril Tapia-Rojas et al.   BRAIN PATHOLOGY

BDNF, via truncated TrkB receptor, modulates GlyT1 and GlyT2 in astrocytes

(2015) Rita I. Aroeira et al.   GLIA

Glial alterations from early to late stages in a model of Alzheimer's disease: Evidence of autophagy involvement in Aβ internalization

(2015) Carlos Pomilio et al.   HIPPOCAMPUS

Treadmill Running Reverses Cognitive Declines due to Alzheimer Disease

(2015) JINKYUNG CHO et al.   MEDICINE AND SCIENCE IN SPORTS AND EXERCISE

TrkB reduction exacerbates Alzheimer’s disease-like signaling aberrations and memory deficits without affecting β-amyloidosis in 5XFAD mice

(2015) L Devi et al.   Translational Psychiatry

Physical Exercise Enhances Cognitive Flexibility as Well as Astrocytic and Synaptic Markers in the Medial Prefrontal Cortex

(2015) Adam T. Brockett et al.   PLoS One

Effects of voluntary and involuntary exercise on cognitive functions, and VEGF and BDNF levels in adolescent rats

(2014) N Uysal et al.   BIOTECHNIC & HISTOCHEMISTRY

Astrocyte-Derived BDNF Supports Myelin Protein Synthesis after Cuprizone-Induced Demyelination

(2014) C. G. Fulmer et al.   JOURNAL OF NEUROSCIENCE

The dual role of astrocyte activation and reactive gliosis

(2014) Milos Pekny et al.   NEUROSCIENCE LETTERS

Proliferation in the Alzheimer Hippocampus Is due to Microglia, Not Astroglia, and Occurs at Sites of Amyloid Deposition

(2014) Michael W. Marlatt et al.   NEURAL PLASTICITY

A Phenotypic Change But Not Proliferation Underlies Glial Responses in Alzheimer Disease

(2013) Alberto Serrano-Pozo et al.   AMERICAN JOURNAL OF PATHOLOGY

Physical exercise increases GFAP expression and induces morphological changes in hippocampal astrocytes

(2013) Lisiani Saur et al.   Brain Structure & Function

Enriched environment and physical activity reverse astrogliodegeneration in the hippocampus of AD transgenic mice

(2013) J J Rodríguez et al.   Cell Death & Disease

An Update of Animal Models of Alzheimer Disease with a Reevaluation of Plaque Depositions

(2013) Jung-Eun Lee et al.   Experimental Neurobiology

Environmental enrichment prevents astroglial pathological changes in the hippocampus of APP transgenic mice, model of Alzheimer's disease

(2012) Juan Beauquis et al.   EXPERIMENTAL NEUROLOGY

Attenuating astrocyte activation accelerates plaque pathogenesis in APP/PS1 mice

(2012) Andrew W. Kraft et al.   FASEB JOURNAL

Multiple effects of physical activity on molecular and cognitive signs of brain aging: can exercise slow neurodegeneration and delay Alzheimer’s disease?

(2012) B M Brown et al.   MOLECULAR PSYCHIATRY

Weight loss and Alzheimer's disease: temporal and aetiologic connections

(2012) Giuseppe Sergi et al.   PROCEEDINGS OF THE NUTRITION SOCIETY

Neurogenesis in Alzheimer’s disease

(2011) José J. Rodríguez et al.   JOURNAL OF ANATOMY

Age and gene overexpression interact to abolish nesting behavior in Tg2576 amyloid precursor protein (APP) mice

(2010) Daniel W. Wesson et al.   BEHAVIOURAL BRAIN RESEARCH

Complex environment experience rescues impaired neurogenesis, enhances synaptic plasticity, and attenuates neuropathology in familial Alzheimer’s disease-linked APPswe/PS1ΔE9 mice

(2010) Yuan-Shih Hu et al.   FASEB JOURNAL

Environmental enrichment fails to rescue working memory deficits, neuron loss, and neurogenesis in APP/PS1KI mice

(2010) Marie-Caroline Cotel et al.   NEUROBIOLOGY OF AGING

Motor deficits, neuron loss, and reduced anxiety coinciding with axonal degeneration and intraneuronal Aβ aggregation in the 5XFAD mouse model of Alzheimer's disease

(2010) Sadim Jawhar et al.   NEUROBIOLOGY OF AGING

Astrocytes in Alzheimer’s disease

(2010) Alexei Verkhratsky et al.   Neurotherapeutics

Age effects on the regulation of adult hippocampal neurogenesis by physical activity and environmental enrichment in the APP23 mouse model of Alzheimer disease

(2009) Sebastian Mirochnic et al.   HIPPOCAMPUS

Wheel-running in a transgenic mouse model of Alzheimer's disease: Protection or symptom?

(2008) Helene Richter et al.   BEHAVIOURAL BRAIN RESEARCH

Environmental enrichment enhances cellular plasticity in transgenic mice with Alzheimer-like pathology

(2008) Arne Herring et al.   EXPERIMENTAL NEUROLOGY

Short-term exercise in aged Tg2576 mice alters neuroinflammation and improves cognition

(2008) A. Parachikova et al.   NEUROBIOLOGY OF DISEASE

Non-Cell-Autonomous Effects of Presenilin 1 Variants on Enrichment-Mediated Hippocampal Progenitor Cell Proliferation and Differentiation

(2008) Se Hoon Choi et al.   NEURON

Cognition-enhancing and anxiolytic effects of memantine

(2008) Rimante Minkeviciene et al.   NEUROPHARMACOLOGY