Physical Exercise Prevented Stress‐Induced Anxiety via Improving Brain RNA Methylation

m6A-RNA Demethylase FTO Inhibitors Impair Self-Renewal in Glioblastoma Stem Cells

(2021) Sarah Huff et al.   ACS Chemical Biology

FTO-mediated cytoplasmic m6Am demethylation adjusts stem-like properties in colorectal cancer cell

(2021) Sébastien Relier et al.   Nature Communications

Physical exercise rescues cocaine-evoked synaptic deficits in motor cortex

(2021) Tong Cheng et al.   MOLECULAR PSYCHIATRY

N6-methyladenosine modification of FAAH mRNA in circSTAG1-regulated astrocyte dysfunction and depressive-like behaviors

(2020) Rongrong Huang et al.   BIOLOGICAL PSYCHIATRY

Tet3 ablation in adult brain neurons increases anxiety-like behavior and regulates cognitive function in mice

(2020) Cláudia Antunes et al.   MOLECULAR PSYCHIATRY

Endocannabinoid Signaling Collapse Mediates Stress-Induced Amygdalo-Cortical Strengthening

(2020) David J. Marcus et al.   NEURON

Ketamine disinhibits dendrites and enhances calcium signals in prefrontal dendritic spines

(2020) Farhan Ali et al.   Nature Communications

Identification of a prefrontal cortex-to-amygdala pathway for chronic stress-induced anxiety

(2020) Wei-Zhu Liu et al.   Nature Communications

Emotion reactivity-related brain network analysis in generalized anxiety disorder: a task fMRI study

(2020) Jian Li et al.   BMC Psychiatry

DEPRESSION AND ANXIETY ARE COMMON AMONG PATIENTS WITH CIRRHOSIS

(2020) Ruben Hernaez et al.   Clinical Gastroenterology and Hepatology

Exercise and dietary intervention ameliorate high-fat diet-induced NAFLD and liver aging by inducing lipophagy

(2020) Yu Gao et al.   Redox Biology

Exercise training improves motor skill learning via selective activation of mTOR

(2019) Kai Chen et al.   Science Advances

FTO: An Emerging Molecular Player in Neuropsychiatric Diseases

(2019) P.K. Annapoorna et al.   NEUROSCIENCE

Abnormal dynamic functional connectivity density in patients with generalized anxiety disorder

(2019) Yuyan Chen et al.   JOURNAL OF AFFECTIVE DISORDERS

Synaptic N6-methyladenosine (m6A) epitranscriptome reveals functional partitioning of localized transcripts

(2018) Daria Merkurjev et al.   NATURE NEUROSCIENCE

Mettl14 Is Essential for Epitranscriptomic Regulation of Striatal Function and Learning

(2018) Jessica L. Koranda et al.   NEURON

RNA-Dependent Intergenerational Inheritance of Enhanced Synaptic Plasticity after Environmental Enrichment

(2018) Eva Benito et al.   Cell Reports

The Role of m6A/m-RNA Methylation in Stress Response Regulation

(2018) Mareen Engel et al.   NEURON

Combined adult neurogenesis and BDNF mimic exercise effects on cognition in an Alzheimer’s mouse model

(2018) Se Hoon Choi et al.   SCIENCE

The Impact of Stress and Major Depressive Disorder on Hippocampal and Medial Prefrontal Cortex Morphology

(2018) Emily L. Belleau et al.   BIOLOGICAL PSYCHIATRY

m6A facilitates hippocampus-dependent learning and memory through YTHDF1

(2018) Hailing Shi et al.   NATURE

Effect of Prefrontal Cortex Stimulation on Regulation of Amygdala Response to Threat in Individuals With Trait Anxiety

(2018) Maria Ironside et al.   JAMA Psychiatry

S-Adenosylmethionine (SAMe) for Neuropsychiatric Disorders

(2017) Anup Sharma et al.   JOURNAL OF CLINICAL PSYCHIATRY

Dopamine D1 receptor subtype mediates acute stress-induced dendritic growth in excitatory neurons of the medial prefrontal cortex and contributes to suppression of stress susceptibility in mice

(2017) R Shinohara et al.   MOLECULAR PSYCHIATRY

Social stress induces neurovascular pathology promoting depression

(2017) Caroline Menard et al.   NATURE NEUROSCIENCE

Physical exercise as an epigenetic modulator of brain plasticity and cognition

(2017) Jansen Fernandes et al.   NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS

Treadmill exercise suppressed stress-induced dendritic spine elimination in mouse barrel cortex and improved working memory via BDNF/TrkB pathway

(2017) K Chen et al.   Translational Psychiatry

Previous Ketamine Produces an Enduring Blockade of Neurochemical and Behavioral Effects of Uncontrollable Stress

(2016) J. Amat et al.   JOURNAL OF NEUROSCIENCE

Metabolism of ketone bodies during exercise and training: physiological basis for exogenous supplementation

(2016) Mark Evans et al.   JOURNAL OF PHYSIOLOGY-LONDON

Cellular and molecular basis for stress-induced depression

(2016) J-S Seo et al.   MOLECULAR PSYCHIATRY

LKB1 loss links serine metabolism to DNA methylation and tumorigenesis

(2016) Filippos Kottakis et al.   NATURE

Region-specific roles of the corticotropin-releasing factor–urocortin system in stress

(2016) Marloes J. A. G. Henckens et al.   NATURE REVIEWS NEUROSCIENCE

Exercise promotes the expression of brain derived neurotrophic factor (BDNF) through the action of the ketone body β-hydroxybutyrate

(2016) Sama F Sleiman et al.   eLife

Acute stress affects the global DNA methylation profile in rat brain: Modulation by physical exercise

(2015) Gelson M. Rodrigues et al.   BEHAVIOURAL BRAIN RESEARCH

Histone Methylation Dynamics and Gene Regulation Occur through the Sensing of One-Carbon Metabolism

(2015) Samantha J. Mentch et al.   Cell Metabolism

Physical exercise and acute restraint stress differentially modulate hippocampal brain-derived neurotrophic factor transcripts and epigenetic mechanisms in mice

(2015) Alessandro Ieraci et al.   HIPPOCAMPUS

An association study of the m6A genes with major depressive disorder in Chinese Han population

(2015) Tingfu Du et al.   JOURNAL OF AFFECTIVE DISORDERS

DNA methyltransferase 3a regulates osteoclast differentiation by coupling to an S-adenosylmethionine–producing metabolic pathway

(2015) Keizo Nishikawa et al.   NATURE MEDICINE

Increased Signaling via Adenosine A1 Receptors, Sleep Deprivation, Imipramine, and Ketamine Inhibit Depressive-like Behavior via Induction of Homer1a

(2015) Tsvetan Serchov et al.   NEURON

The Genetics of Stress-Related Disorders: PTSD, Depression and Anxiety Disorders

(2015) Jordan W Smoller   NEUROPSYCHOPHARMACOLOGY

Effects of Exercise on Anxiety and Depression Disorders: Review of Meta- Analyses and Neurobiological Mechanisms

(2014) Mirko Wegner et al.   CNS & Neurological Disorders-Drug Targets

Nicotinamide N-methyltransferase knockdown protects against diet-induced obesity

(2014) Daniel Kraus et al.   NATURE

The dynamic epitranscriptome: N6-methyladenosine and gene expression control

(2014) Kate D. Meyer et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

mTOR and the health benefits of exercise

(2014) Kurt Watson et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

A METTL3–METTL14 complex mediates mammalian nuclear RNA N6-adenosine methylation

(2013) Jianzhao Liu et al.   Nature Chemical Biology

The fat mass and obesity associated gene (Fto) regulates activity of the dopaminergic midbrain circuitry

(2013) Martin E Hess et al.   NATURE NEUROSCIENCE

S-adenosylmethionine in Liver Health, Injury, and Cancer

(2012) Shelly C. Lu et al.   PHYSIOLOGICAL REVIEWS

mTOR-Dependent Synapse Formation Underlies the Rapid Antidepressant Effects of NMDA Antagonists

(2010) N. Li et al.   SCIENCE

Stress, memory and the amygdala

(2009) Benno Roozendaal et al.   NATURE REVIEWS NEUROSCIENCE

The Neurocircuitry of Fear, Stress and Anxiety Disorders

(2009) Lisa M Shin et al.   NEUROPSYCHOPHARMACOLOGY