Toxoplasma gondii virulence factor ROP1 reduces parasite susceptibility to murine and human innate immune restriction

Live-attenuated ME49Δcdpk3 strain of Toxoplasma gondii protects against acute and chronic toxoplasmosis

(2022) Minmin Wu et al.   npj Vaccines

Leaked Mitochondrial C1QBP Inhibits Activation of the DNA Sensor cGAS

(2021) Kun Song et al.   JOURNAL OF IMMUNOLOGY

VEuPathDB: the eukaryotic pathogen, vector and host bioinformatics resource center

(2021) Beatrice Amos et al.   NUCLEIC ACIDS RESEARCH

Proximity-Labeling Reveals Novel Host and Parasite Proteins at the Toxoplasma Parasitophorous Vacuole Membrane

(2021) Alicja M. Cygan et al.   mBio

Novel roles of dense granule protein 12 (GRA12) in Toxoplasma gondii infection

(2020) Jin‐Lei Wang et al.   FASEB JOURNAL

A Comprehensive Subcellular Atlas of the Toxoplasma Proteome via hyperLOPIT Provides Spatial Context for Protein Functions

(2020) Konstantin Barylyuk et al.   Cell Host & Microbe

Genome-wide screens identify Toxoplasma gondii determinants of parasite fitness in IFNγ-activated murine macrophages

(2020) Yifan Wang et al.   Nature Communications

Mechanisms of Human Innate Immune Evasion by Toxoplasma gondii

(2019) Tatiane S. Lima et al.   Frontiers in Cellular and Infection Microbiology

Human GBP1 is a microbe‐specific gatekeeper of macrophage apoptosis and pyroptosis

(2019) Daniel Fisch et al.   EMBO JOURNAL

Toxoplasma gondii effector TgIST blocks type I interferon signaling to promote infection

(2019) Sumit K. Matta et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

In Vivo CRISPR Screen Identifies TgWIP as a Toxoplasma Modulator of Dendritic Cell Migration

(2019) Lamba Omar Sangaré et al.   Cell Host & Microbe

A CRISPR platform for targeted in vivo screens identifies Toxoplasma gondii virulence factors in mice

(2019) Joanna Young et al.   Nature Communications

Differential requirements for cyclase-associated protein (CAP) in actin-dependent processes of Toxoplasma gondii

(2019) Alex Hunt et al.   eLife

Toxoplasma Effector TgIST Targets Host IDO1 to Antagonize the IFN-γ-Induced Anti-parasitic Response in Human Cells

(2018) Hironori Bando et al.   Frontiers in Immunology

The PRIDE database and related tools and resources in 2019: improving support for quantification data

(2018) Yasset Perez-Riverol et al.   NUCLEIC ACIDS RESEARCH

Toxoplasma gondii MAF1b Binds the Host Cell MIB Complex To Mediate Mitochondrial Association

(2017) Felice D. Kelly et al.   mSphere

A Genome-wide CRISPR Screen in Toxoplasma Identifies Essential Apicomplexan Genes

(2016) Saima M. Sidik et al.   CELL

Host Mitochondrial Association Evolved in the Human Parasite Toxoplasma gondii via Neofunctionalization of a Gene Duplicate

(2016) Yaw Adomako-Ankomah et al.   GENETICS

The Perseus computational platform for comprehensive analysis of (prote)omics data

(2016) Stefka Tyanova et al.   NATURE METHODS

Host Mitochondrial Association Evolved in the Human Parasite Toxoplasma gondii via Neofunctionalization of a Gene Duplicate

(2016) Yaw Adomako-Ankomah et al.   GENETICS

Ubiquitin systems mark pathogen-containing vacuoles as targets for host defense by guanylate binding proteins

(2015) Arun K. Haldar et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Rhoptry Proteins ROP5 and ROP18 Are Major Murine Virulence Factors in Genetically Divergent South American Strains of Toxoplasma gondii

(2015) Michael S. Behnke et al.   PLoS Genetics

GRA25 Is a Novel Virulence Factor of Toxoplasma gondii and Influences the Host Immune Response

(2014) A. J. Shastri et al.   INFECTION AND IMMUNITY

Dual Role for Inflammasome Sensors NLRP1 and NLRP3 in Murine Resistance to Toxoplasma gondii

(2014) G. Gorfu et al.   mBio

Toxoplasma Effector MAF1 Mediates Recruitment of Host Mitochondria and Impacts the Host Response

(2014) Lena Pernas et al.   PLOS BIOLOGY

NLRP1 Is an Inflammasome Sensor for Toxoplasma gondii

(2013) Sarah E. Ewald et al.   INFECTION AND IMMUNITY

NIH Image to ImageJ: 25 years of image analysis

(2012) Caroline A Schneider et al.   NATURE METHODS

p32/gC1qR is indispensable for fetal development and mitochondrial translation: importance of its RNA-binding ability

(2012) Mikako Yagi et al.   NUCLEIC ACIDS RESEARCH

A Toxoplasma gondii Pseudokinase Inhibits Host IRG Resistance Proteins

(2012) Martin C. Fleckenstein et al.   PLOS BIOLOGY

The Rhoptry Proteins ROP18 and ROP5 Mediate Toxoplasma gondii Evasion of the Murine, But Not the Human, Interferon-Gamma Response

(2012) Wendy Niedelman et al.   PLoS Pathogens

The Polymorphic Pseudokinase ROP5 Controls Virulence in Toxoplasma gondii by Regulating the Active Kinase ROP18

(2012) Michael S. Behnke et al.   PLoS Pathogens

Toxoplasma Polymorphic Effectors Determine Macrophage Polarization and Intestinal Inflammation

(2011) Kirk D.C. Jensen et al.   Cell Host & Microbe

Type II Toxoplasma gondii KU80 Knockout Strains Enable Functional Analysis of Genes Required for Cyst Development and Latent Infection

(2011) Barbara A. Fox et al.   EUKARYOTIC CELL

Andromeda: A Peptide Search Engine Integrated into the MaxQuant Environment

(2011) Jürgen Cox et al.   JOURNAL OF PROTEOME RESEARCH

Polymorphic family of injected pseudokinases is paramount in Toxoplasma virulence

(2011) M. L. Reese et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Virulence differences in Toxoplasma mediated by amplification of a family of polymorphic pseudokinases

(2011) M. S. Behnke et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Phosphorylation of Immunity-Related GTPases by a Toxoplasma gondii-Secreted Kinase Promotes Macrophage Survival and Virulence

(2010) Sarah J. Fentress et al.   Cell Host & Microbe

Differential expression analysis for sequence count data

(2010) Simon Anders et al.   GENOME BIOLOGY

Tagging of Endogenous Genes in aToxoplasma gondiiStrain Lacking Ku80

(2009) My-Hang Huynh et al.   EUKARYOTIC CELL

Inhibition of RIG-I and MDA5-dependent antiviral response by gC1qR at mitochondria

(2009) L. Xu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Disruption of the Toxoplasma gondii Parasitophorous Vacuole by IFNγ-Inducible Immunity-Related GTPases (IRG Proteins) Triggers Necrotic Cell Death

(2009) Yang O. Zhao et al.   PLoS Pathogens

MaxQuant enables high peptide identification rates, individualized p.p.b.-range mass accuracies and proteome-wide protein quantification

(2008) Jürgen Cox et al.   NATURE BIOTECHNOLOGY

Kiss and spit: the dual roles of Toxoplasma rhoptries

(2007) John C. Boothroyd et al.   NATURE REVIEWS MICROBIOLOGY