Melatonin inhibits autophagy and endoplasmic reticulum stress in mice with carbon tetrachloride-induced fibrosis

Melatonin limits the expression of profibrogenic genes and ameliorates the progression of hepatic fibrosis in mice

(2015) Irene Crespo et al.   Translational Research

Cellular and molecular mechanisms in liver fibrogenesis

(2014) Erica Novo et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

The transcription factor CHOP, a central component of the transcriptional regulatory network induced upon CCl4 intoxication in mouse liver, is not a critical mediator of hepatotoxicity

(2014) Gisela Campos et al.   ARCHIVES OF TOXICOLOGY

Chloroquine Improved Carbon Tetrachloride-Induced Liver Fibrosis through Its Inhibition of the Activation of Hepatic Stellate Cells: Role of Autophagy

(2014) Wei He et al.   BIOLOGICAL & PHARMACEUTICAL BULLETIN

Melatonin Inhibits mTOR-Dependent Autophagy during Liver Ischemia/Reperfusion

(2014) Jung-Woo Kang et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

Paeoniflorin alleviates liver fibrosis by inhibiting HIF-1α through mTOR-dependent pathway

(2014) Yanling Zhao et al.   FITOTERAPIA

Curcumin attenuates angiogenesis in liver fibrosis and inhibits angiogenic properties of hepatic stellate cells

(2014) Feng Zhang et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Inhibition of Autophagy Contributes to Melatonin-Mediated Neuroprotection Against Transient Focal Cerebral Ischemia in Rats

(2014) Yongqiu Zheng et al.   JOURNAL OF PHARMACOLOGICAL SCIENCES

Melatonin modulates the autophagic response in acute liver failure induced by the rabbit hemorrhagic disease virus

(2014) Beatriz San-Miguel et al.   JOURNAL OF PINEAL RESEARCH

Melatonin Inhibits Endoplasmic Reticulum Stress and Epithelial-Mesenchymal Transition during Bleomycin-Induced Pulmonary Fibrosis in Mice

(2014) Hui Zhao et al.   PLoS One

mTOR and autophagy: A dynamic relationship governed by nutrients and energy

(2014) E.A. Dunlop et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Autophagy in Hepatic Fibrosis

(2014) Yang Song et al.   Biomed Research International

Autophagy: A Multifaceted Partner in Liver Fibrosis

(2014) Ariane Mallat et al.   Biomed Research International

Everolimus is a potent inhibitor of activated hepatic stellate cell functionsin vitroandin vivo, while demonstrating anti-angiogenic activities

(2013) Anne-Christine Piguet et al.   CLINICAL SCIENCE

Endoplasmic reticulum stress induces fibrogenic activity in hepatic stellate cells through autophagy

(2013) Virginia Hernández-Gea et al.   JOURNAL OF HEPATOLOGY

Melatonin treatment reduces endoplasmic reticulum stress and modulates the unfolded protein response in rabbits with lethal fulminant hepatitis of viral origin

(2013) María J. Tuñón et al.   JOURNAL OF PINEAL RESEARCH

Folic acid and melatonin ameliorate carbon tetrachloride-induced hepatic injury, oxidative stress and inflammation in rats

(2013) Hossam Ebaid et al.   Nutrition & Metabolism

UVRAG

(2012) Zhen Zhao et al.   Autophagy

Beclin1: A role in membrane dynamics and beyond

(2012) Ellen Wirawan et al.   Autophagy

Autophagy Releases Lipid That Promotes Fibrogenesis by Activated Hepatic Stellate Cells in Mice and in Human Tissues

(2012) Virginia Hernández–Gea et al.   GASTROENTEROLOGY

Melatonin inhibits matrix metalloproteinase-9 activity by binding to its active site

(2012) Deep Sankar Rudra et al.   JOURNAL OF PINEAL RESEARCH

Myofibroblasts revert to an inactive phenotype during regression of liver fibrosis

(2012) T. Kisseleva et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Autophagy, mitochondria and oxidative stress: cross-talk and redox signalling

(2011) Jisun Lee et al.   BIOCHEMICAL JOURNAL

A role for autophagy during hepatic stellate cell activation

(2011) Lien F.R. Thoen et al.   JOURNAL OF HEPATOLOGY

Autophagy Signaling Through Reactive Oxygen Species

(2010) Ju Huang et al.   ANTIOXIDANTS & REDOX SIGNALING

mTOR regulation of autophagy

(2010) Chang Hwa Jung et al.   FEBS LETTERS

Potent antifibrotic activity of mTOR inhibitors sirolimus and everolimus but not of cyclosporine A and tacrolimus in experimental liver fibrosis

(2010) Eleonora Patsenker et al.   JOURNAL OF HEPATOLOGY

Glutamine Prevents Fibrosis Development in Rats with Colitis Induced by 2,4,6-Trinitrobenzene Sulfonic Acid

(2010) Beatriz San-Miguel et al.   JOURNAL OF NUTRITION

Melatonin attenuates apoptotic liver damage in fulminant hepatic failure induced by the rabbit hemorrhagic disease virus

(2010) María J. Tuñón et al.   JOURNAL OF PINEAL RESEARCH

Mammalian autophagy: core molecular machinery and signaling regulation

(2009) Zhifen Yang et al.   CURRENT OPINION IN CELL BIOLOGY

Melatonin ameliorates experimental hepatic fibrosis induced by carbon tetrachloride in rats

(2009) Ru-Tao Hong et al.   WORLD JOURNAL OF GASTROENTEROLOGY

The unfolded protein response regulator GRP78/BiP is required for endoplasmic reticulum integrity and stress-induced autophagy in mammalian cells

(2008) J Li et al.   CELL DEATH AND DIFFERENTIATION