JAK2/STAT3 activation by melatonin attenuates the mitochondrial oxidative damage induced by myocardial ischemia/reperfusion injury

Effect of interleukin 6 deficiency on the expression of Bcl-2 and Bax in the murine heart

(2014) Karol A. Kamiński et al.   Pharmacological Reports

Experimental models of melatonin-deficient hypertension 

(2013) Fedor Simko   Frontiers in Bioscience-Landmark

The effects of curcumin post-treatment against myocardial ischemia and reperfusion by activation of the JAK2/STAT3 signaling pathway

(2012) Weixun Duan et al.   BASIC RESEARCH IN CARDIOLOGY

Release of a humoral circulating cardioprotective factor by remote ischemic preconditioning is dependent on preserved neural pathways in diabetic patients

(2012) Rebekka Vibjerg Jensen et al.   BASIC RESEARCH IN CARDIOLOGY

Mouse hematopoietic cell-targeted STAT3 deletion: stem/progenitor cell defects, mitochondrial dysfunction, ROS overproduction, and a rapid aging-like phenotype

(2012) C. Mantel et al.   BLOOD

Cardiovascular effects of melatonin receptor agonists

(2012) Ludovit Paulis et al.   EXPERT OPINION ON INVESTIGATIONAL DRUGS

The role of melatonin in acute myocardial infarction

(2012) Alberto Dominguez-Rodriguez   Frontiers in Bioscience-Landmark

Melatonin protects against isoproterenol-induced alterations in cardiac mitochondrial energy-metabolizing enzymes, apoptotic proteins, and assists in complete recovery from myocardial injury in rats

(2012) Debasri Mukherjee et al.   JOURNAL OF PINEAL RESEARCH

Neuroprotective effect of melatonin against hypoxia-induced retinal ganglion cell death in neonatal rats

(2012) Charanjit Kaur et al.   JOURNAL OF PINEAL RESEARCH

Melatonin improved rat cardiac mitochondria and survival rate in septic heart injury

(2012) Hongmin Zhang et al.   JOURNAL OF PINEAL RESEARCH

Toll-like receptor 3 (TLR3) protects retinal pigmented epithelium (RPE) cells from oxidative stress through a STAT3-dependent mechanism

(2012) Amit K. Patel et al.   MOLECULAR IMMUNOLOGY

Fasudil Protects the Heart against Ischemia-Reperfusion Injury by Attenuating Endoplasmic Reticulum Stress and Modulating SERCA Activity: The Differential Role for PI3K/Akt and JAK2/STAT3 Signaling Pathways

(2012) Yapeng Li et al.   PLoS One

Cardiac Protection by Preconditioning Is Generated via an Iron-Signal Created by Proteasomal Degradation of Iron Proteins

(2012) Baruch E. Bulvik et al.   PLoS One

Mitochondrial STAT3 Activation and Cardioprotection by Ischemic Postconditioning in Pigs With Regional Myocardial Ischemia/Reperfusion

(2011) Gerd Heusch et al.   CIRCULATION RESEARCH

Basic Mechanisms Involved in the Anti-Cancer Effects of Melatonin

(2011) M. D. Mediavilla et al.   CURRENT MEDICINAL CHEMISTRY

Intracoronary melatonin increases coronary blood flow and cardiac function through β-adrenoreceptors, MT1/MT2 receptors, and nitric oxide in anesthetized pigs

(2011) Elena Grossini et al.   JOURNAL OF PINEAL RESEARCH

Cytoprotective effects of melatonin on astroglial cells subjected to palmitic acid treatment in vitro

(2011) Zhen Wang et al.   JOURNAL OF PINEAL RESEARCH

Melatonin as a natural ally against oxidative stress: a physicochemical examination

(2011) Annia Galano et al.   JOURNAL OF PINEAL RESEARCH

Evidence that membrane-bound G protein-coupled melatonin receptors MT1 and MT2 are not involved in the neuroprotective effects of melatonin in focal cerebral ischemia

(2011) Ulkan Kilic et al.   JOURNAL OF PINEAL RESEARCH

Interleukin-6 autocrine signaling mediates melatonin MT1/2receptor-induced STAT3 Tyr705phosphorylation

(2011) Winnie W. I. Lau et al.   JOURNAL OF PINEAL RESEARCH

Leptin-induced cardioprotection involves JAK/STAT signaling that may be linked to the mitochondrial permeability transition pore

(2010) Christopher C. T. Smith et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Beneficial effects of melatonin in cardiovascular disease

(2010) Russel J. Reiter et al.   ANNALS OF MEDICINE

Inhibition of mitochondrial permeability transition pore opening: the holy grail of cardioprotection

(2010) Gerd Heusch et al.   BASIC RESEARCH IN CARDIOLOGY

Role of cGMP-PKG signaling in the protection of neonatal rat cardiac myocytes subjected to simulated ischemia/reoxygenation

(2010) Aniko Gorbe et al.   BASIC RESEARCH IN CARDIOLOGY

Inhibition of permeability transition pore opening by mitochondrial STAT3 and its role in myocardial ischemia/reperfusion

(2010) Kerstin Boengler et al.   BASIC RESEARCH IN CARDIOLOGY

A Combination of Melatonin and Alpha Lipoic Acid has Greater Cardioprotective Effect than Either of them Singly Against Cadmium-Induced Oxidative Damage

(2010) Raktim Mukherjee et al.   Cardiovascular Toxicology

Protective effects of hemoglobin-based oxygen carrier given to isolated heart during ischemia via attenuation of mitochondrial oxidative damage

(2010) Tao Li et al.   FREE RADICAL BIOLOGY AND MEDICINE

Protective role of melatonin in myocardial oxidative damage induced by mercury in murine model

(2010) Mitali Jindal et al.   HUMAN & EXPERIMENTAL TOXICOLOGY

Increased susceptibility to Ca2+-induced permeability transition and to cytochrome c release in rat heart mitochondria with aging: effect of melatonin

(2010) Giuseppe Petrosillo et al.   JOURNAL OF PINEAL RESEARCH

Melatonin protects against heart ischemia-reperfusion injury by inhibiting mitochondrial permeability transition pore opening

(2009) Giuseppe Petrosillo et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Melatonin suppresses AOM/DSS-induced large bowel oncogenesis in rats

(2008) Takuji Tanaka et al.   CHEMICO-BIOLOGICAL INTERACTIONS

The myocardial JAK/STAT pathway: From protection to failure

(2008) K BOENGLER et al.   PHARMACOLOGY & THERAPEUTICS