Multiple pkd and piezo gene family members are required for atrioventricular valve formation

Extracellular mechanical forces drive endocardial cell volume decrease during zebrafish cardiac valve morphogenesis

(2022) Hélène Vignes et al.   DEVELOPMENTAL CELL

Genotype–Phenotype Relationships in the Context of Transcriptional Adaptation and Genetic Robustness

(2021) Gabrielius Jakutis et al.   Annual Review of Genetics

Emerging role of Piezo ion channels in cardiovascular development

(2021) Vandit Shah et al.   DEVELOPMENTAL DYNAMICS

Insights Into the Molecular Mechanisms of Polycystic Kidney Diseases

(2021) Valeriia Y. Vasileva et al.   Frontiers in Physiology

Bioelectric signaling and the control of cardiac cell identity in response to mechanical forces

(2021) Hajime Fukui et al.   SCIENCE

Nfatc1 Promotes Interstitial Cell Formation During Cardiac Valve Development in Zebrafish

(2020) Felix Gunawan et al.   CIRCULATION RESEARCH

Genetic compensation of γ CaMKII, an evolutionarily conserved gene

(2020) Sarah C. Rothschild et al.   GENE

Piezo1 is required for outflow tract and aortic valve development.

(2020) Adèle Faucherre et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Antagonistic Activities of Vegfr3/Flt4 and Notch1b Fine-tune Mechanosensitive Signaling during Zebrafish Cardiac Valvulogenesis

(2020) Federica Fontana et al.   Cell Reports

Focal adhesions are essential to drive zebrafish heart valve morphogenesis

(2019) Felix Gunawan et al.   JOURNAL OF CELL BIOLOGY

Genetic compensation triggered by mutant mRNA degradation

(2019) Mohamed A. El-Brolosy et al.   NATURE

Mechanotransduction in cardiovascular morphogenesis and tissue engineering

(2019) Anne-Laure Duchemin et al.   CURRENT OPINION IN GENETICS & DEVELOPMENT

Valves Are a Conserved Feature of the Zebrafish Lymphatic System

(2019) Masahiro Shin et al.   DEVELOPMENTAL CELL

Mechanically activated piezo channels modulate outflow tract valve development through the Yap1 and Klf2-Notch signaling axis

(2019) Anne-Laure Duchemin et al.   eLife

In vivo DNA assembly using common laboratory bacteria: A re-emerging tool to simplify molecular cloning

(2019) Jake F. Watson et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Zebrafish Vestigial Like Family Member 4b Is Required for Valvulogenesis Through Sequestration of Transcription Factor Myocyte Enhancer Factor 2c

(2019) Chang Xue et al.   Frontiers in Cell and Developmental Biology

Combinatorial genetic replenishments in myocardial and outflow tract tissues restore heart function in tnnt2 mutant zebrafish

(2019) Lian Liu et al.   Biology Open

The mechanobiology of zebrafish cardiac valve leaflet formation

(2018) Alessio Paolini et al.   CURRENT OPINION IN CELL BIOLOGY

HHEX is a transcriptional regulator of the VEGFC/FLT4/PROX1 signaling axis during vascular development

(2018) Sébastien Gauvrit et al.   Nature Communications

Myosin1D is an evolutionarily conserved regulator of animal left–right asymmetry

(2018) Thomas Juan et al.   Nature Communications

Mechanically activated ion channel PIEZO1 is required for lymphatic valve formation

(2018) Keiko Nonomura et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The flow responsive transcription factor Klf2 is required for myocardial wall integrity by modulating Fgf signaling

(2018) Seyed Javad Rasouli et al.   eLife

Activation of the hypothalamic feeding centre upon visual prey detection

(2017) Akira Muto et al.   Nature Communications

Regulation of cardiomyocyte behavior in zebrafish trabeculation by Neuregulin 2a signaling

(2017) S. Javad Rasouli et al.   Nature Communications

Regulation of posterior body and epidermal morphogenesis in zebrafish by localized Yap1 and Wwtr1

(2017) David Kimelman et al.   eLife

Bi-allelic Mutations in PKD1L1 Are Associated with Laterality Defects in Humans

(2016) Francesco Vetrini et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Hemodynamics driven cardiac valve morphogenesis

(2016) Emily Steed et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Real-time 3D visualization of cellular rearrangements during cardiac valve formation

(2016) Jenny Pestel et al.   DEVELOPMENT

klf2a couples mechanotransduction and zebrafish valve morphogenesis through fibronectin synthesis

(2016) Emily Steed et al.   Nature Communications

Oscillatory Flow Modulates Mechanosensitive klf2a Expression through trpv4 and trpp2 during Heart Valve Development

(2015) Emilie Heckel et al.   CURRENT BIOLOGY

Reverse Genetic Screening Reveals Poor Correlation between Morpholino-Induced and Mutant Phenotypes in Zebrafish

(2015) Fatma O. Kok et al.   DEVELOPMENTAL CELL

Intracardiac flow dynamics regulate atrioventricular valve morphogenesis

(2014) Stamatia Kalogirou et al.   CARDIOVASCULAR RESEARCH

Piezo Proteins: Regulators of Mechanosensation and Other Cellular Processes

(2014) Sviatoslav N. Bagriantsev et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Endothelial Cilia Mediate Low Flow Sensing during Zebrafish Vascular Development

(2014) Jacky G. Goetz et al.   Cell Reports

Pkd1 Regulates Lymphatic Vascular Morphogenesis during Development

(2014) Baptiste Coxam et al.   Cell Reports

Efficient CRISPR/Cas9 genome editing with low off-target effects in zebrafish

(2013) A. Hruscha et al.   DEVELOPMENT

Efficient multiplex biallelic zebrafish genome editing using a CRISPR nuclease system

(2013) Li-En Jao et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Heart Valve Structure and Function in Development and Disease

(2011) Robert B. Hinton et al.   Annual Review of Physiology

Protein Kinase D2 Controls Cardiac Valve Formation in Zebrafish by Regulating Histone Deacetylase 5 Activity

(2011) Steffen Just et al.   CIRCULATION

Distinct Cellular Mechanisms of Blood Vessel Fusion in the Zebrafish Embryo

(2011) Lukas Herwig et al.   CURRENT BIOLOGY

CaMK-II is a PKD2 target that promotes pronephric kidney development and stabilizes cilia

(2011) Sarah C. Rothschild et al.   DEVELOPMENT

Pkd1l1 establishes left-right asymmetry and physically interacts with Pkd2

(2011) S. Field et al.   DEVELOPMENT

Pkd1l1 complexes with Pkd2 on motile cilia and functions to establish the left-right axis

(2011) K. Kamura et al.   DEVELOPMENT

In vivo protein trapping produces a functional expression codex of the vertebrate proteome

(2011) Karl J Clark et al.   NATURE METHODS

The activation of membrane targeted CaMK-II in the zebrafish Kupffer's vesicle is required for left-right asymmetry

(2010) L. Francescatto et al.   DEVELOPMENT

The ADPKD genes pkd1a/b and pkd2 regulate extracellular matrix formation

(2010) S. Mangos et al.   Disease Models & Mechanisms

The changing epidemiology of congenital heart disease

(2010) Teun van der Bom et al.   Nature Reviews Cardiology

Fluid shear stress stimulates phosphorylation-dependent nuclear export of HDAC5 and mediates expression of KLF2 and eNOS

(2009) W. Wang et al.   BLOOD

Tbx5-mediated expression of Ca2+/calmodulin-dependent protein kinase II is necessary for zebrafish cardiac and pectoral fin morphogenesis

(2009) Sarah C. Rothschild et al.   DEVELOPMENTAL BIOLOGY

Reversing Blood Flows Act through klf2a to Ensure Normal Valvulogenesis in the Developing Heart

(2009) Julien Vermot et al.   PLOS BIOLOGY

High-resolution in situ hybridization to whole-mount zebrafish embryos

(2007) Christine Thisse et al.   Nature Protocols