HHEX is a transcriptional regulator of the VEGFC/FLT4/PROX1 signaling axis during vascular development

Mir-126 is a conserved modulator of lymphatic development

(2018) Zacharias Kontarakis et al.   DEVELOPMENTAL BIOLOGY

On the development of the hepatopancreatic ductal system

(2017) Alethia Villasenor et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Proline-Rich Homeodomain protein (PRH/HHEX) is a suppressor of breast tumour growth

(2017) R M Kershaw et al.   Oncogenesis

Vegfc acts through ERK to induce sprouting and differentiation of trunk lymphatic progenitors

(2016) Masahiro Shin et al.   DEVELOPMENT

Acute myeloid leukemia requires Hhex to enable PRC2-mediated epigenetic repression ofCdkn2a

(2016) Benjamin J. Shields et al.   GENES & DEVELOPMENT

Misregulation of the proline rich homeodomain (PRH/HHEX) protein in cancer cells and its consequences for tumour growth and invasion

(2016) Kevin Gaston et al.   Cell and Bioscience

Meta- and Orthogonal Integration of Influenza “OMICs” Data Defines a Role for UBR4 in Virus Budding

(2015) Shashank Tripathi et al.   Cell Host & Microbe

Nonvenous Origin of Dermal Lymphatic Vasculature

(2015) I. Martinez-Corral et al.   CIRCULATION RESEARCH

Lymphatic vessels arise from specialized angioblasts within a venous niche

(2015) J. Nicenboim et al.   NATURE

Vegfc Regulates Bipotential Precursor Division and Prox1 Expression to Promote Lymphatic Identity in Zebrafish

(2015) Katarzyna Koltowska et al.   Cell Reports

Tip cell-specific requirement for an atypical Gpr124- and Reck-dependent Wnt/β-catenin pathway during brain angiogenesis

(2015) Benoit Vanhollebeke et al.   eLife

A crucial role for the homeodomain transcription factor Hhex in lymphopoiesis

(2014) J. T. Jackson et al.   BLOOD

Ccbe1 regulates Vegfc-mediated induction of Vegfr3 signaling during embryonic lymphangiogenesis

(2014) L. Le Guen et al.   DEVELOPMENT

Vegfd can compensate for loss of Vegfc in zebrafish facial lymphatic sprouting

(2014) J. W. Astin et al.   DEVELOPMENT

The Prox1–Vegfr3 feedback loop maintains the identity and the number of lymphatic endothelial cell progenitors

(2014) R. Sathish Srinivasan et al.   GENES & DEVELOPMENT

Genetics of lymphatic anomalies

(2014) Pascal Brouillard et al.   JOURNAL OF CLINICAL INVESTIGATION

Sox18 Genetically Interacts With VegfC to Regulate Lymphangiogenesis in Zebrafish

(2013) Solei Cermenati et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

featureCounts: an efficient general purpose program for assigning sequence reads to genomic features

(2013) Y. Liao et al.   BIOINFORMATICS

Bone Morphogenetic Protein 2 Signaling Negatively Modulates Lymphatic Development in Vertebrate Embryos

(2013) William P. Dunworth et al.   CIRCULATION RESEARCH

A truncation allele in vascular endothelial growth factor c reveals distinct modes of signaling during lymphatic and vascular development

(2013) J. A. Villefranc et al.   DEVELOPMENT

TGF  signaling is required for sprouting lymphangiogenesis during lymphatic network development in the skin

(2013) J. M. James et al.   DEVELOPMENT

G13 Controls Angiogenesis through Regulation of VEGFR-2 Expression

(2013) Kishor Kumar Sivaraj et al.   DEVELOPMENTAL CELL

Enhanced Lymph Vessel Density, Remodeling, and Inflammation Are Reflected by Gene Expression Signatures in Dermal Lymphatic Endothelial Cells in Type 2 Diabetes

(2013) M. Haemmerle et al.   DIABETES

Kraken: A set of tools for quality control and analysis of high-throughput sequence data

(2013) Matthew P.A. Davis et al.   METHODS

PRH/HHex inhibits the migration of breast and prostate epithelial cells through direct transcriptional regulation of Endoglin

(2013) R M Kershaw et al.   ONCOGENE

STAR: ultrafast universal RNA-seq aligner

(2012) Alexander Dobin et al.   BIOINFORMATICS

lyve1 expression reveals novel lymphatic vessels and new mechanisms for lymphatic vessel development in zebrafish

(2012) K. S. Okuda et al.   DEVELOPMENT

Prox1 dosage controls the number of lymphatic endothelial cell progenitors and the formation of the lymphovenous valves

(2011) R. S. Srinivasan et al.   GENES & DEVELOPMENT

Genes regulating lymphangiogenesis control venous valve formation and maintenance in mice

(2011) Eleni Bazigou et al.   JOURNAL OF CLINICAL INVESTIGATION

Efficient design and assembly of custom TALEN and other TAL effector-based constructs for DNA targeting

(2011) Tomas Cermak et al.   NUCLEIC ACIDS RESEARCH

Identification and functional analysis of endothelial tip cell-enriched genes

(2010) R. del Toro et al.   BLOOD

Lymphangiogenesis: Molecular Mechanisms and Future Promise

(2010) Tuomas Tammela et al.   CELL

VEGFR-3 ligand-binding and kinase activity are required for lymphangiogenesis but not for angiogenesis

(2010) Luqing Zhang et al.   CELL RESEARCH

Moesin1 and Ve-cadherin are required in endothelial cells during in vivo tubulogenesis

(2010) Y. Wang et al.   DEVELOPMENT

Cranial vasculature in zebrafish forms by angioblast cluster-derived angiogenesis

(2010) Kira Proulx et al.   DEVELOPMENTAL BIOLOGY

PRH/Hhex Controls Cell Survival through Coordinate Transcriptional Regulation of Vascular Endothelial Growth Factor Signaling

(2010) P. Noy et al.   MOLECULAR AND CELLULAR BIOLOGY

Functional Heterogeneity of Embryonic Stem Cells Revealed through Translational Amplification of an Early Endodermal Transcript

(2010) Maurice A. Canham et al.   PLOS BIOLOGY

Vegfc/Flt4 signalling is suppressed by Dll4 in developing zebrafish intersegmental arteries

(2009) B. M. Hogan et al.   DEVELOPMENT

A genetic screen for vascular mutants in zebrafish reveals dynamic roles for Vegf/Plcg1 signaling during artery development

(2009) L.D. Covassin et al.   DEVELOPMENTAL BIOLOGY

The haemangioblast generates haematopoietic cells through a haemogenic endothelium stage

(2009) Christophe Lancrin et al.   NATURE

ccbe1 is required for embryonic lymphangiogenesis and venous sprouting

(2009) Benjamin M Hogan et al.   NATURE GENETICS

PRH/Hex: an oligomeric transcription factor and multifunctional regulator of cell fate

(2008) Abdenour Soufi et al.   BIOCHEMICAL JOURNAL

High-resolution in situ hybridization to whole-mount zebrafish embryos

(2007) Christine Thisse et al.   Nature Protocols