Piezo Proteins: Regulators of Mechanosensation and Other Cellular Processes

Functional role of mechanosensitive ion channel Piezo1 in human periodontal ligament cells

(2015) Ying Jin et al.   ANGLE ORTHODONTIST

Mutations in PIEZO2 Cause Gordon Syndrome, Marden-Walker Syndrome, and Distal Arthrogryposis Type 5

(2014) Margaret J. McMillin et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Merkel Cells Transduce and Encode Tactile Stimuli to Drive Aβ-Afferent Impulses

(2014) Ryo Ikeda et al.   CELL

Piezo1 Is as a Novel Trefoil Factor Family 1 Binding Protein that Promotes Gastric Cancer Cell Mobility In Vitro

(2014) Xiao-Ning Yang et al.   DIGESTIVE DISEASES AND SCIENCES

Functional Role for Piezo1 in Stretch-evoked Ca2+Influx and ATP Release in Urothelial Cell Cultures

(2014) Tatsuya Miyamoto et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Piezo2 expression in corneal afferent neurons

(2014) Romke Bron et al.   JOURNAL OF COMPARATIVE NEUROLOGY

Epidermal Merkel cells are mechanosensory cells that tune mammalian touch receptors

(2014) Srdjan Maksimovic et al.   NATURE

Piezo2 is required for Merkel-cell mechanotransduction

(2014) Seung-Hyun Woo et al.   NATURE

Piezo1 integration of vascular architecture with physiological force

(2014) Jing Li et al.   NATURE

Piezo2 channel conductance and localization domains in Merkel cells of rat whisker hair follicles

(2014) Ryo Ikeda et al.   NEUROSCIENCE LETTERS

Mechanical allodynia

(2014) Stéphane Lolignier et al.   PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY

Mechanosensitivity is mediated directly by the lipid membrane in TRAAK and TREK1 K+channels

(2014) Stephen G. Brohawn et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Neuronal mechanism for acute mechanosensitivity in tactile-foraging waterfowl

(2014) E. R. Schneider et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Piezo1, a mechanically activated ion channel, is required for vascular development in mice

(2014) S. S. Ranade et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Tuning Piezo ion channels to detect molecular-scale movements relevant for fine touch

(2014) Kate Poole et al.   Nature Communications

Trigeminal neuralgia

(2014) J. M. Zakrzewska et al.   BMJ-British Medical Journal

Diversification and Specialization of Touch Receptors in Skin

(2014) D. M. Owens et al.   Cold Spring Harbor Perspectives in Medicine

Human PIEZO1: Removing Inactivation

(2013) Chilman Bae et al.   BIOPHYSICAL JOURNAL

To shrink or not to shrink

(2013) N. Mohandas   BLOOD

Multiple clinical forms of dehydrated hereditary stomatocytosis arise from mutations in PIEZO1

(2013) I. Andolfo et al.   BLOOD

Mechano-Gated Ion Channels in Sensory Systems

(2013) Patrick Delmas et al.   CELL

Disorders of red cell volume regulation

(2013) Patrick G. Gallagher   CURRENT OPINION IN HEMATOLOGY

Piezo1-dependent stretch-activated channels are inhibited by Polycystin-2 in renal tubular epithelial cells

(2013) Rémi Peyronnet et al.   EMBO REPORTS

Piezo1 plays a role in erythrocyte volume homeostasis

(2013) A. Faucherre et al.   HAEMATOLOGICA

The Purified Mechanosensitive Channel TREK-1 Is Directly Sensitive to Membrane Tension

(2013) Catherine Berrier et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Runx1 Controls Terminal Morphology and Mechanosensitivity of VGLUT3-expressing C-Mechanoreceptors

(2013) S. Lou et al.   JOURNAL OF NEUROSCIENCE

The Sensory Neurons of Touch

(2013) Victoria E. Abraira et al.   NEURON

Identification and Analysis of Putative Homologues of Mechanosensitive Channels in Pathogenic Protozoa

(2013) David L. Prole et al.   PLoS One

Gain-of-function mutations in the mechanically activated ion channel PIEZO2 cause a subtype of Distal Arthrogryposis

(2013) B. Coste et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Xerocytosis is caused by mutations that alter the kinetics of the mechanosensitive channel PIEZO1

(2013) C. Bae et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A role for Piezo2 in EPAC1-dependent mechanical allodynia

(2013) N Eijkelkamp et al.   Nature Communications

GTP-dependent run-up of Piezo2-type mechanically activated currents in rat dorsal root ganglion neurons

(2013) Zhanfeng Jia et al.   Molecular Brain

Role of Epac in brain and heart

(2012) Anne-Coline Laurent et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

Mutations in the mechanotransduction protein PIEZO1 are associated with hereditary xerocytosis

(2012) R. Zarychanski et al.   BLOOD

Gating the mechanical channel Piezo1

(2012) Philip A. Gottlieb et al.   Channels

Molecular force transduction by ion channels – diversity and unifying principles

(2012) Sergei Sukharev et al.   JOURNAL OF CELL SCIENCE

Rodents Rely on Merkel Cells for Texture Discrimination Tasks

(2012) S. M. Maricich et al.   JOURNAL OF NEUROSCIENCE

The conductance of red blood cells from sickle cell patients: ion selectivity and inhibitors

(2012) Y.-L. Ma et al.   JOURNAL OF PHYSIOLOGY-LONDON

Piezo proteins are pore-forming subunits of mechanically activated channels

(2012) Bertrand Coste et al.   NATURE

Seventy-five genetic loci influencing the human red blood cell

(2012) Pim van der Harst et al.   NATURE

The role of Drosophila Piezo in mechanical nociception

(2012) Sung Eun Kim et al.   NATURE

Loss of the Integrin-Activating Transmembrane Protein Fam38A (Piezo1) Promotes a Switch to a Reduced Integrin-Dependent Mode of Cell Migration

(2012) Brian J. McHugh et al.   PLoS One

Inflammatory Signals Enhance Piezo2-Mediated Mechanosensitive Currents

(2012) Adrienne E. Dubin et al.   Cell Reports

The Mechanosensitive Ion Channel Piezo1 Is Inhibited by the Peptide GsMTx4

(2011) Chilman Bae et al.   BIOCHEMISTRY

Osmosensory Mechanisms in Cellular and Systemic Volume Regulation

(2011) S. F. Pedersen et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Molecular mechanisms of mechanotransduction in mammalian sensory neurons

(2011) Patrick Delmas et al.   NATURE REVIEWS NEUROSCIENCE

A mechanosensitive ion channel regulating cell volume

(2010) Susan Z. Hua et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Pressing and squeezing with Piezos

(2010) Bernd Nilius   EMBO REPORTS

Hypoxia Activates a Ca2+-Permeable Cation Conductance Sensitive to Carbon Monoxide and to GsMTx-4 in Human and Mouse Sickle Erythrocytes

(2010) David H. Vandorpe et al.   PLoS One

Local Membrane Deformations Activate Ca2+-Dependent K+ and Anionic Currents in Intact Human Red Blood Cells

(2010) Agnieszka Dyrda et al.   PLoS One

Piezo1 and Piezo2 Are Essential Components of Distinct Mechanically Activated Cation Channels

(2010) B. Coste et al.   SCIENCE

Mammalian somatosensory mechanotransduction

(2009) Makoto Tsunozaki et al.   CURRENT OPINION IN NEUROBIOLOGY

Target Promiscuity and Heterogeneous Effects of Tarantula Venom Peptides Affecting Na+and K+Ion Channels

(2009) Elisa Redaelli et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Mechanosensitive TRP channels in cardiovascular pathophysiology

(2009) Ryuji Inoue et al.   PHARMACOLOGY & THERAPEUTICS