Unique Structure and Distinctive Properties of the Ancient and Ubiquitous Gamma-Type Envelope Glycoprotein

Structure of the Core Postfusion Porcine Endogenous Retrovirus Fusion Protein

(2022) Trevor T. Dean et al.   mBio

Identification of Copper Transporter 1 as a Receptor for Feline Endogenous Retrovirus ERV-DC14

(2022) Sandrine Tury et al.   JOURNAL OF VIROLOGY

Deep-Time Structural Evolution of Retroviral and Filoviral Surface Envelope Proteins

(2022) Isidro Hötzel   JOURNAL OF VIROLOGY

Evolution and Genetic Diversity of the Retroviral Envelope in Anamniotes

(2022) Yicong Chen et al.   JOURNAL OF VIROLOGY

Structural insights into the lysophospholipid brain uptake mechanism and its inhibition by syncytin-2

(2022) Maria Martinez-Molledo et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Evolution and antiviral activity of a human protein of retroviral origin

(2022) John A. Frank et al.   SCIENCE

Cross-species transmission of an ancient endogenous retrovirus and convergent co-option of its envelope gene in two mammalian orders

(2022) J’Zaria Simpson et al.   PLoS Genetics

A structure and evolutionary-based classification of solute carriers

(2022) Evandro Ferrada et al.   iScience

Across the Hall from Pioneers

(2021) Alan Rein   Viruses-Basel

Therapeutic potential of the human endogenous retroviral envelope protein HEMO: a pan‐cancer analysis

(2021) Amélie Kasperek et al.   Molecular Oncology

A novel class III endogenous retrovirus with a class I envelope gene in African frogs with an intact genome and developmentally regulated transcripts in Xenopus tropicalis

(2021) Venkat R. K. Yedavalli et al.   Retrovirology

Patterns of Coevolutionary Adaptations across Time and Space in Mouse Gammaretroviruses and Three Restrictive Host Factors

(2021) Guney Boso et al.   Viruses-Basel

Intramolecular quality control: HIV-1 envelope gp160 signal-peptide cleavage as a functional folding checkpoint

(2021) Nicholas McCaul et al.   Cell Reports

Identification and Characteristics of Fusion Peptides Derived From Enveloped Viruses

(2021) Camille Lozada et al.   Frontiers in Chemistry

ICTV Virus Taxonomy Profile: Retroviridae 2021

(2021) John Coffin et al.   JOURNAL OF GENERAL VIROLOGY

Genome-Wide Characterization of Zebrafish Endogenous Retroviruses Reveals Unexpected Diversity in Genetic Organizations and Functional Potentials

(2021) Jun Bai et al.   Microbiology Spectrum

Comprehensive genomic analysis reveals dynamic evolution of endogenous retroviruses that code for retroviral-like protein domains

(2020) Mahoko Takahashi Ueda et al.   Mobile DNA

Structure of the Receptor Binding Domain of EnvP(b)1, an Endogenous Retroviral Envelope Protein Expressed in Human Tissues

(2020) Kevin R. McCarthy et al.   mBio

Origins and evolutionary consequences of ancient endogenous retroviruses

(2019) Welkin E. Johnson   NATURE REVIEWS MICROBIOLOGY

Reverse Engineering Provides Insights on the Evolution of Subgroups A to E Avian Sarcoma and Leukosis Virus Receptor Specificity

(2019) Mark J. Federspiel   Viruses-Basel

Cytoplasmic R-peptide of murine leukemia virus envelope protein negatively regulates its interaction with the cell surface receptor

(2019) Yoshinao Kubo et al.   VIROLOGY

Deltaretroviruses have circulated since at least the Paleogene and infected a broad range of mammalian species

(2019) Tomáš Hron et al.   Retrovirology

CAT1/SLC7A1 acts as a cellular receptor for bovine leukemia virus infection

(2019) Lanlan Bai et al.   FASEB JOURNAL

A comprehensive review of signal peptides: Structure, roles, and applications

(2018) Hajar Owji et al.   EUROPEAN JOURNAL OF CELL BIOLOGY

Signal peptide of HIV envelope protein impacts glycosylation and antigenicity of gp120

(2018) Jason Yolitz et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Remnants of an Ancient Deltaretrovirus in the Genomes of Horseshoe Bats (Rhinolophidae)

(2018) Tomáš Hron et al.   Viruses-Basel

Genomic evolution, recombination, and inter-strain diversity of chelonid alphaherpesvirus 5 from Florida and Hawaii green sea turtles with fibropapillomatosis

(2018) Cheryl L. Morrison et al.   PeerJ

Nomenclature for endogenous retrovirus (ERV) loci

(2018) Robert J. Gifford et al.   Retrovirology

Identification of the receptor used by the ecotropic mouse GLN endogenous retrovirus

(2018) Jhen Tsang et al.   JOURNAL OF VIROLOGY

Capture of a hyena-specific retroviral envelope gene with placental expression associated in evolution with the unique emergence among carnivorans of hemochorial placentation in Hyaenidae

(2018) Mathis Funk et al.   JOURNAL OF VIROLOGY

Native structure of a retroviral envelope protein and its conformational change upon interaction with the target cell

(2017) Christiane Riedel et al.   JOURNAL OF STRUCTURAL BIOLOGY

Mutation of the Putative Immunosuppressive Domain of the Retroviral Envelope Glycoprotein Compromises Infectivity

(2017) Urszula Eksmond et al.   JOURNAL OF VIROLOGY

A Cell Fusion-Based Screening Method Identifies Glycosylphosphatidylinositol-Anchored Protein Ly6e as the Receptor for Mouse Endogenous Retroviral Envelope Syncytin-A

(2017) Agathe Bacquin et al.   JOURNAL OF VIROLOGY

Transmission, Evolution, and Endogenization: Lessons Learned from Recent Retroviral Invasions

(2017) Alex D. Greenwood et al.   MICROBIOLOGY AND MOLECULAR BIOLOGY REVIEWS

An endogenous retroviral envelope syncytin and its cognate receptor identified in the viviparous placentalMabuyalizard

(2017) Guillaume Cornelis et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Discovery of an endogenous Deltaretrovirus in the genome of long-fingered bats (Chiroptera: Miniopteridae)

(2017) Helena Farkašová et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

HEMO, an ancestral endogenous retroviral envelope protein shed in the blood of pregnant women and expressed in pluripotent stem cells and tumors

(2017) Odile Heidmann et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Introducing a cleavable signal peptide enhances the packaging efficiency of lentiviral vectors pseudotyped with Japanese encephalitis virus envelope proteins

(2017) Hanyang Liu et al.   VIRUS RESEARCH

Co-option of endogenous viral sequences for host cell function

(2017) John A .Frank et al.   Current Opinion in Virology

Retroviruses of the RDR superinfection interference group: ancient origins and broad host distribution of a promiscuous Env gene

(2017) Anindita Sinha et al.   Current Opinion in Virology

Co-option of an endogenous retrovirus envelope for host defense in hominid ancestors

(2017) Daniel Blanco-Melo et al.   eLife

Dynein Regulators Are Important for Ecotropic Murine Leukemia Virus Infection

(2016) Roger Valle-Tenney et al.   JOURNAL OF VIROLOGY

Effects of individually silenced N-glycosylation sites and non-synonymous single-nucleotide polymorphisms on the fusogenic function of human syncytin-2

(2016) Lina Cui et al.   Cell Adhesion & Migration

gEVE: a genome-based endogenous viral element database provides comprehensive viral protein-coding sequences in mammalian genomes

(2016) So Nakagawa et al.   Database-The Journal of Biological Databases and Curation

Tracking interspecies transmission and long-term evolution of an ancient retrovirus using the genomes of modern mammals

(2016) William E Diehl et al.   eLife

Fighting Fire with Fire: Endogenous Retrovirus Envelopes as Restriction Factors

(2015) Ray Malfavon-Borja et al.   JOURNAL OF VIROLOGY

Viral membrane fusion

(2015) Stephen C. Harrison   VIROLOGY

Macropinocytosis Is the Entry Mechanism of Amphotropic Murine Leukemia Virus

(2014) Izabela Rasmussen et al.   JOURNAL OF VIROLOGY

Furin cleavage of the Moloney murine leukemia virus Env precursor reorganizes the spike structure

(2014) M. Sjoberg et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Pan-vertebrate comparative genomics unmasks retrovirus macroevolution

(2014) Alexander Hayward et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Identification of a Novel Subgroup of Koala Retrovirus from Koalas in Japanese Zoos

(2013) T. Shojima et al.   JOURNAL OF VIROLOGY

A Novel Recombinant Retrovirus in the Genomes of Modern Birds Combines Features of Avian and Mammalian Retroviruses

(2013) J. E. Henzy et al.   JOURNAL OF VIROLOGY

Crystal Structures of Beta- and Gammaretrovirus Fusion Proteins Reveal a Role for Electrostatic Stapling in Viral Entry

(2013) H. Aydin et al.   JOURNAL OF VIROLOGY

Isolation, Identification, and Characterization of Novel Arenaviruses, the Etiological Agents of Boid Inclusion Body Disease

(2013) U. Hetzel et al.   JOURNAL OF VIROLOGY

Pushing the endogenous envelope

(2013) J. E. Henzy et al.   PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

Paleovirology of 'syncytins', retroviral env genes exapted for a role in placentation

(2013) C. Lavialle et al.   PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

Broad-scale phylogenomics provides insights into retrovirus-host evolution

(2013) A. Hayward et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

An exogenous retrovirus isolated from koalas with malignant neoplasias in a US zoo

(2013) W. Xu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A novel human endogenous retroviral protein inhibits cell-cell fusion

(2013) Jun Sugimoto et al.   Scientific Reports

Dual Host-Virus Arms Races Shape an Essential Housekeeping Protein

(2013) Ann Demogines et al.   PLOS BIOLOGY

Marburg Virus Glycoprotein GP2: pH-Dependent Stability of the Ectodomain α-Helical Bundle

(2012) Joseph S. Harrison et al.   BIOCHEMISTRY

Crystal Structure of the Marburg Virus GP2 Core Domain in Its Postfusion Conformation

(2012) Jayne F. Koellhoffer et al.   BIOCHEMISTRY

Library screening and receptor-directed targeting of gammaretroviral vectors

(2012) Peter M Mazari et al.   Future Microbiology

Visualization of the Two-Step Fusion Process of the Retrovirus Avian Sarcoma/Leukosis Virus by Cryo-Electron Tomography

(2012) G. Cardone et al.   JOURNAL OF VIROLOGY

Mus spicilegus Endogenous Retrovirus HEMV Uses Murine Sodium-Dependent Myo-Inositol Transporter 1 as a Receptor

(2012) C. H. Tipper et al.   JOURNAL OF VIROLOGY

Construction of a Gammaretrovirus with a Novel Tropism and Wild-Type Replication Kinetics Capable of Using Human APJ as Entry Receptor

(2012) S. Bahrami et al.   JOURNAL OF VIROLOGY

Betaretroviral Envelope Subunits Are Noncovalently Associated and Restricted to the Mammalian Class

(2012) J. E. Henzy et al.   JOURNAL OF VIROLOGY

From ancestral infectious retroviruses to bona fide cellular genes: Role of the captured syncytins in placentation

(2012) A. Dupressoir et al.   PLACENTA

Maturation cleavage of the murine leukemia virus Env precursor separates the transmembrane subunits to prime it for receptor triggering

(2012) R. Loving et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Ancestral capture of syncytin-Car1, a fusogenic endogenous retroviral envelope gene involved in placentation and conserved in Carnivora

(2012) G. Cornelis et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A mutant retroviral receptor restricts virus superinfection interference and productive infection

(2012) Meihong Liu et al.   Retrovirology

Comparison of the convergent receptor utilization of a retargeted feline leukemia virus envelope with a naturally-occurring porcine endogenous retrovirus A

(2012) Peter M. Mazari et al.   VIROLOGY

Identification, Characterization, and In Vitro Culture of Highly Divergent Arenaviruses from Boa Constrictors and Annulated Tree Boas: Candidate Etiological Agents for Snake Inclusion Body Disease

(2012) M. D. Stenglein et al.   mBio

Mechanisms for Env Glycoprotein Acquisition by Retroviruses

(2011) Marc C. Johnson   AIDS RESEARCH AND HUMAN RETROVIRUSES

Requirements for Mouse Mammary Tumor Virus Rem Signal Peptide Processing and Function

(2011) H. Byun et al.   JOURNAL OF VIROLOGY

Ebola virus entry requires the cholesterol transporter Niemann–Pick C1

(2011) Jan E. Carette et al.   NATURE

A pair of co-opted retroviral envelope syncytin genes is required for formation of the two-layered murine placental syncytiotrophoblast

(2011) A. Dupressoir et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The receptors for gibbon ape leukemia virus and amphotropic murine leukemia virus are not downregulated in productively infected cells

(2011) Meihong Liu et al.   Retrovirology

Escape from R-peptide deletion in a γ-retrovirus

(2011) Irene C. Schneider et al.   VIROLOGY

Charge-Surrounded Pockets and Electrostatic Interactions with Small Ions Modulate the Activity of Retroviral Fusion Proteins

(2011) Daniel Lamb et al.   PLoS Pathogens

Evolution of Functional and Sequence Variants of the Mammalian XPR1 Receptor for Mouse Xenotropic Gammaretroviruses and the Human-Derived Retrovirus XMRV

(2010) Y. Yan et al.   JOURNAL OF VIROLOGY

Retroviral infection in vivo requires an immune escape virulence factor encrypted in the envelope protein of oncoretroviruses

(2010) Géraldine Schlecht-Louf et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Identification of a receptor for an extinct virus

(2010) S. J. Soll et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Coupling of receptor interference and a host-dependent post-binding entry deficiency in a gammaretroviral envelope protein

(2010) Shervin Bahrami et al.   Retrovirology

Two distinct mechanisms regulate recruitment of murine leukemia virus envelope protein to retroviral assembly sites

(2010) Tiffany M. Lucas et al.   VIROLOGY

Evolution of Teleost Fish Retroviruses: Characterization of New Retroviruses with Cellular Genes

(2009) H. A. Basta et al.   JOURNAL OF VIROLOGY

Foreign Glycoproteins Can Be Actively Recruited to Virus Assembly Sites during Pseudotyping

(2009) R. L. Jorgenson et al.   JOURNAL OF VIROLOGY

The Signal Peptide of a Simple Retrovirus Envelope Functions as a Posttranscriptional Regulator of Viral Gene Expression

(2009) M. Caporale et al.   JOURNAL OF VIROLOGY

Jaagsiekte Sheep Retrovirus Encodes a Regulatory Factor, Rej, Required for Synthesis of Gag Protein

(2009) A. Hofacre et al.   JOURNAL OF VIROLOGY

Syncytin-A knockout mice demonstrate the critical role in placentation of a fusogenic, endogenous retrovirus-derived, envelope gene

(2009) A. Dupressoir et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Single-round selection yields a unique retroviral envelope utilizing GPR172A as its host receptor

(2009) P. M. Mazari et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Identification of an endogenous retroviral envelope gene with fusogenic activity and placenta-specific expression in the rabbit: a new "syncytin" in a third order of mammals

(2009) Odile Heidmann et al.   Retrovirology

Functional Characterization of the Human Placental Fusogenic Membrane Protein Syncytin 21

(2008) Chie-Pein Chen et al.   BIOLOGY OF REPRODUCTION

Spontaneous Heteromerization of Gammaretrovirus Envelope Proteins: a Possible Novel Mechanism of Retrovirus Restriction

(2008) M. Dewannieux et al.   JOURNAL OF VIROLOGY

Intersubunit Disulfide Isomerization Controls Membrane Fusion of Human T-Cell Leukemia Virus Env

(2008) K. Li et al.   JOURNAL OF VIROLOGY

Viral membrane fusion

(2008) Stephen C Harrison   NATURE STRUCTURAL & MOLECULAR BIOLOGY

A placenta-specific receptor for the fusogenic, endogenous retrovirus-derived, human syncytin-2

(2008) C. Esnault et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA