Brain‐Targeted HFn‐Cu‐REGO Nanoplatform for Site‐Specific Delivery and Manipulation of Autophagy and Cuproptosis in Glioblastoma

Self-Adaptive Single-Atom Catalyst Boosting Selective Ferroptosis in Tumor Cells

(2022) Fangfang Cao et al.   ACS Nano

Copper-Based Metal–Organic Framework Overcomes Cancer Chemoresistance through Systemically Disrupting Dynamically Balanced Cellular Redox Homeostasis

(2022) Jia Liu et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

PKCβII phosphorylates ACSL4 to amplify lipid peroxidation to induce ferroptosis

(2022) Hai-Liang Zhang et al.   NATURE CELL BIOLOGY

Checkpoint: Inspecting the barriers in glioblastoma immunotherapies

(2022) Isabelle Preddy et al.   SEMINARS IN CANCER BIOLOGY

Harnessing Bifunctional Ferritin with Kartogenin Loading for Mesenchymal Stem Cell Capture and Enhancing Chondrogenesis in Cartilage Regeneration

(2022) En Ren et al.   Advanced Healthcare Materials

Nano-enabled photosynthesis in tumours to activate lipid peroxidation for overcoming cancer resistances

(2022) Jun Jiang et al.   BIOMATERIALS

Ferroptosis at the intersection of lipid metabolism and cellular signaling

(2022) Deguang Liang et al.   MOLECULAR CELL

Copper-induced cell death

(2022) Martha A. Kahlson et al.   SCIENCE

Copper induces cell death by targeting lipoylated TCA cycle proteins

(2022) Peter Tsvetkov et al.   SCIENCE

A targeted nanomodulator capable of manipulating tumor microenvironment against metastasis

(2022) Hailong Tian et al.   JOURNAL OF CONTROLLED RELEASE

Enhancing the therapeutic efficacy of nanoparticles for cancer treatment using versatile targeted strategies

(2022) Hailong Tian et al.   Journal of Hematology & Oncology

Cholesterol-associated lysosomal disorder triggers cell death of hematological malignancy: Dynamic analysis on cytotoxic effects of LW-218

(2021) Po Hu et al.   Acta Pharmaceutica Sinica B

Self-assembled ternary hybrid nanodrugs for overcoming tumor resistance and metastasis

(2021) Xu Cheng et al.   Acta Pharmaceutica Sinica B

Ferritin: A Multifunctional Nanoplatform for Biological Detection, Imaging Diagnosis, and Drug Delivery

(2021) Ningning Song et al.   ACCOUNTS OF CHEMICAL RESEARCH

Glucose starvation induces autophagy via ULK1-mediated activation of PIKfyve in an AMPK-dependent manner

(2021) Cansu Karabiyik et al.   DEVELOPMENTAL CELL

Patient-reported outcomes in a phase II randomised study of regorafenib compared with lomustine in patients with relapsed glioblastoma (the REGOMA trial)

(2021) Giuseppe Lombardi et al.   EUROPEAN JOURNAL OF CANCER

A cascaded copper-based nanocatalyst by modulating glutathione and cyclooxygenase-2 for hepatocellular carcinoma therapy

(2021) Hailong Tian et al.   JOURNAL OF COLLOID AND INTERFACE SCIENCE

Enhanced adsorption and degradation of methylene blue over mixed niobium-cerium oxide – Unraveling the synergy between Nb and Ce in advanced oxidation processes

(2021) Lukasz Wolski et al.   JOURNAL OF HAZARDOUS MATERIALS

TAK1 mediates neuronal pyroptosis in early brain injury after subarachnoid hemorrhage

(2021) Pengfei Xu et al.   Journal of Neuroinflammation

Regorafenib in Recurrent Glioblastoma Patients: A Large and Monocentric Real-Life Study

(2021) Giuseppe Lombardi et al.   Cancers

One-Step Integration of Tumor Microenvironment-Responsive Calcium and Copper Peroxides Nanocomposite for Enhanced Chemodynamic/Ion-Interference Therapy

(2021) Bin Liu et al.   ACS Nano

Endogenous Copper for Nanocatalytic Oxidative Damage and Self-Protection Pathway Breakage of Cancer

(2021) Yuedong Guo et al.   ACS Nano

Application of glutathione depletion in cancer therapy: Enhanced ROS-based therapy, ferroptosis, and chemotherapy

(2021) Boyi Niu et al.   BIOMATERIALS

Lipid peroxidation index of particulate matter: Novel metric for quantifying intrinsic oxidative potential and predicting toxic responses

(2021) Sumit K. Dey et al.   Redox Biology

Therapeutic strategies of glioblastoma (GBM): The current advances in the molecular targets and bioactive small molecule compounds

(2021) Hui Liu et al.   Acta Pharmaceutica Sinica B

ROS-augmented and tumor-microenvironment responsive biodegradable nanoplatform for enhancing chemo-sonodynamic therapy

(2020) Jie An et al.   BIOMATERIALS

DNA-methylation-mediated activating of lncRNA SNHG12 promotes temozolomide resistance in glioblastoma

(2020) Chenfei Lu et al.   Molecular Cancer

Circadian Regulator CLOCK Recruits Immune-Suppressive Microglia into the GBM Tumor Microenvironment

(2020) Peiwen Chen et al.   Cancer Discovery

Near Infrared Fluorescent Nanoplatform for Targeted Intraoperative Resection and Chemotherapeutic Treatment of Glioblastoma

(2020) Derek Reichel et al.   ACS Nano

Bioinspired Copper Single‐Atom Catalysts for Tumor Parallel Catalytic Therapy

(2020) Xiangyu Lu et al.   ADVANCED MATERIALS

Therapeutic paradigm of dual targeting VEGF and PDGF for effectively treating FGF-2 off-target tumors

(2020) Kayoko Hosaka et al.   Nature Communications

Ferroptosis: machinery and regulation

(2020) Xin Chen et al.   Autophagy

Brain-targeted delivery of obidoxime, using aptamer-modified liposomes, for detoxification of organophosphorus compounds

(2020) Yadan Zhang et al.   JOURNAL OF CONTROLLED RELEASE

Cystine transporter SLC7A11/xCT in cancer: ferroptosis, nutrient dependency, and cancer therapy

(2020) Pranavi Koppula et al.   Protein & Cell

Advances in drug delivery technology for the treatment of glioblastoma multiforme

(2020) Gi Doo Cha et al.   JOURNAL OF CONTROLLED RELEASE

Doxorubicin‐loaded nanoparticle coated with endothelial cells‐derived exosomes for immunogenic chemotherapy of glioblastoma

(2020) Chao Zhang et al.   Bioengineering & Translational Medicine

Cu-MOF chemodynamic nanoplatform via modulating glutathione and H2O2 in tumor microenvironment for amplified cancer therapy

(2020) Hailong Tian et al.   JOURNAL OF COLLOID AND INTERFACE SCIENCE

Regorafenib induces lethal autophagy arrest by stabilizing PSAT1 in glioblastoma

(2019) Jingwen Jiang et al.   Autophagy

Synthesis of Copper Peroxide Nanodots for H2O2 Self-Supplying Chemodynamic Therapy

(2019) Li-Sen Lin et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Enhanced Tumor-Specific Disulfiram Chemotherapy by In Situ Cu2+ Chelation-Initiated Nontoxicity-to-Toxicity Transition

(2019) Wencheng Wu et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Ferritin Nanocarrier Traverses the Blood Brain Barrier and Kills Glioma

(2018) Kelong Fan et al.   ACS Nano

Endosomal Size and Membrane Leakiness Influence Proton Sponge-Based Rupture of Endosomal Vesicles

(2018) Lotte M. P. Vermeulen et al.   ACS Nano

Obesity Protects Cancer from Drugs Targeting Blood Vessels

(2018) Yihai Cao   Cell Metabolism

Cancer Lipid Metabolism Confers Antiangiogenic Drug Resistance

(2018) Hideki Iwamoto et al.   Cell Metabolism

Regulation of lipid peroxidation and ferroptosis in diverse species

(2018) Marcus Conrad et al.   GENES & DEVELOPMENT

The TNF receptor family member Fn14 is highly expressed in recurrent glioblastoma and in GBM patient-derived xenografts with acquired temozolomide resistance

(2018) David S Hersh et al.   NEURO-ONCOLOGY

Antibacterial Surface Coating for Bone Scaffolds Based on the Dark Catalytic Effect of Titanium Dioxide

(2018) David Wiedmer et al.   ACS Applied Materials & Interfaces

VEGF-targeted cancer therapeutics—paradoxical effects in endocrine organs

(2014) Yihai Cao   Nature Reviews Endocrinology

H-ferritin-nanocaged doxorubicin nanoparticles specifically target and kill tumors with a single-dose injection

(2014) M. Liang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

RGD-Modified Apoferritin Nanoparticles for Efficient Drug Delivery to Tumors

(2013) Zipeng Zhen et al.   ACS Nano

Off-tumor target—beneficial site for antiangiogenic cancer therapy?

(2010) Yihai Cao   Nature Reviews Clinical Oncology

Positive and Negative Modulation of Angiogenesis by VEGFR1 Ligands

(2009) Y. Cao   Science Signaling