TALE transcription factors: Cofactors no more

Downstream of the HOX genes: Explaining conflicting tumour suppressor and oncogenic functions in cancer

(2022) Richard Morgan et al.   INTERNATIONAL JOURNAL OF CANCER

Pioneer factors as master regulators of the epigenome and cell fate

(2022) Aurelio Balsalobre et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Diversification and Functional Evolution of HOX Proteins

(2022) Narendra Pratap Singh et al.   Frontiers in Cell and Developmental Biology

Transcription factor paralogs orchestrate alternative gene regulatory networks by context-dependent cooperation with multiple cofactors

(2022) Siqian Feng et al.   Nature Communications

Cell-type-specific Hox regulatory strategies orchestrate tissue identity

(2021) Ryan Loker et al.   CURRENT BIOLOGY

Control of mouse limb initiation and antero-posterior patterning by Meis transcription factors

(2021) Irene Delgado et al.   Nature Communications

Uncovering tissue-specific binding features from differential deep learning

(2020) Mike Phuycharoen et al.   NUCLEIC ACIDS RESEARCH

Establishing the pattern of the vertebrate limb

(2020) Caitlin McQueen et al.   DEVELOPMENT

HOX paralogs selectively convert binding of ubiquitous transcription factors into tissue-specific patterns of enhancer activation

(2020) Laure Bridoux et al.   PLoS Genetics

The single-cell transcriptional landscape of mammalian organogenesis

(2019) Junyue Cao et al.   NATURE

‘Building a perfect body’: control of vertebrate organogenesis by PBX-dependent regulatory networks

(2019) Licia Selleri et al.   GENES & DEVELOPMENT

MEIS transcription factors in development and disease

(2019) Dorothea Schulte et al.   DEVELOPMENT

Combinatorial action of NF–Y and TALE at embryonic enhancers defines distinct gene expression programs during zygotic genome activation in zebrafish

(2019) William Stanney et al.   DEVELOPMENTAL BIOLOGY

Coupling the roles of Hox genes to regulatory networks patterning cranial neural crest

(2018) Hugo J. Parker et al.   DEVELOPMENTAL BIOLOGY

Human HOX Proteins Use Diverse and Context-Dependent Motifs to Interact with TALE Class Cofactors

(2018) Amélie Dard et al.   Cell Reports

Cytosine modifications modulate the chromatin architecture of transcriptional enhancers

(2017) Elise A. Mahé et al.   GENOME RESEARCH

HOXA1 and TALE proteins display cross-regulatory interactions and form a combinatorial binding code on HOXA1 targets

(2017) Bony De Kumar et al.   GENOME RESEARCH

MEIS homeodomain proteins facilitate PARP1/ARTD1-mediated eviction of histone H1

(2017) Ann-Christin Hau et al.   JOURNAL OF CELL BIOLOGY

Intragenic Enhancers Attenuate Host Gene Expression

(2017) Senthilkumar Cinghu et al.   MOLECULAR CELL

Cell fate control by pioneer transcription factors

(2016) Makiko Iwafuchi-Doi et al.   DEVELOPMENT

Homeodomain proteins: an update

(2015) Thomas R. Bürglin et al.   CHROMOSOMA

Cellular and molecular insights into Hox protein action

(2015) R. Rezsohazy et al.   DEVELOPMENT

Hoxa2 Selectively Enhances Meis Binding to Change a Branchial Arch Ground State

(2015) Shilu Amin et al.   DEVELOPMENTAL CELL

DNA-dependent formation of transcription factor pairs alters their binding specificity

(2015) Arttu Jolma et al.   NATURE

Sequential Binding of MEIS1 and NKX2-5 on the Popdc2 Gene: A Mechanism for Spatiotemporal Regulation of Enhancers during Cardiogenesis

(2015) Laurent Dupays et al.   Cell Reports

TALE Factors Poise Promoters for Activation by Hox Proteins

(2014) Seong-Kyu Choe et al.   DEVELOPMENTAL CELL

Histone-Fold Domain Protein NF-Y Promotes Chromatin Accessibility for Cell Type-Specific Master Transcription Factors

(2014) Andrew J. Oldfield et al.   MOLECULAR CELL

The Deficiency of Tumor Suppressor Prep1 Accelerates the Onset of Meis1- Hoxa9 Leukemogenesis

(2014) Leila Dardaei et al.   PLoS One

Prep1 and Meis1 competition for Pbx1 binding regulates protein stability and tumorigenesis

(2014) L. Dardaei et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

C/EBPα is an essential collaborator in Hoxa9/Meis1-mediated leukemogenesis

(2014) Cailin Collins et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Meis2 is a Pax6 co-factor in neurogenesis and dopaminergic periglomerular fate specification in the adult olfactory bulb

(2013) Z. Agoston et al.   DEVELOPMENT

Hox regulation of transcription: More complex(es)

(2013) Franck Ladam et al.   DEVELOPMENTAL DYNAMICS

Analysis of the DNA-Binding Profile and Function of TALE Homeoproteins Reveals Their Specialization and Specific Interactions with Hox Genes/Proteins

(2013) Dmitry Penkov et al.   Cell Reports

Divergent Transcriptional Regulatory Logic at the Intersection of Tissue Growth and Developmental Patterning

(2013) Matthew Slattery et al.   PLoS Genetics

Dynamic HoxB4-regulatory network during embryonic stem cell differentiation to hematopoietic cells

(2012) R. Fan et al.   BLOOD

Genetic and physical interaction of Meis2, Pax3 and Pax7 during dorsal midbrain development

(2012) Zsuzsa Agoston et al.   BMC DEVELOPMENTAL BIOLOGY

Genome-wide occupancy links Hoxa2 to Wnt–β-catenin signaling in mouse embryonic development

(2012) Ian J. Donaldson et al.   NUCLEIC ACIDS RESEARCH

Dynamic hydroxymethylation of deoxyribonucleic acid marks differentiation-associated enhancers

(2012) Aurélien A. Sérandour et al.   NUCLEIC ACIDS RESEARCH

Hox Proteins Display a Common and Ancestral Ability to Diversify Their Interaction Mode with the PBC Class Cofactors

(2012) Bruno Hudry et al.   PLOS BIOLOGY

C-terminal domain of MEIS1 converts PKNOX1 (PREP1) into a HOXA9-collaborating oncoprotein

(2011) R. Bisaillon et al.   BLOOD

Identification and characterization of Hoxa9 binding sites in hematopoietic cells

(2011) Y. Huang et al.   BLOOD

Cofactor Binding Evokes Latent Differences in DNA Binding Specificity between Hox Proteins

(2011) Matthew Slattery et al.   CELL

Genome-Wide Analysis of the Binding of the Hox Protein Ultrabithorax and the Hox Cofactor Homothorax in Drosophila

(2011) Siew Woh Choo et al.   PLoS One

Genome-Wide Tissue-Specific Occupancy of the Hox Protein Ultrabithorax and Hox Cofactor Homothorax in Drosophila

(2011) Matthew Slattery et al.   PLoS One

PBX1 Genomic Pioneer Function Drives ERα Signaling Underlying Progression in Breast Cancer

(2011) Luca Magnani et al.   PLoS Genetics

Prep1 (pKnox1)-deficiency leads to spontaneous tumor development in mice and accelerates EμMyc lymphomagenesis: A tumor suppressor role for Prep1

(2010) E. Longobardi et al.   Molecular Oncology

Meis2 competes with the Groucho co-repressor Tle4 for binding to Otx2 and specifies tectal fate without induction of a secondary midbrain-hindbrain boundary organizer

(2009) Z. Agoston et al.   DEVELOPMENT

Meis Cofactors Control HDAC and CBP Accessibility at Hox-Regulated Promoters during Zebrafish Embryogenesis

(2009) Seong-Kyu Choe et al.   DEVELOPMENTAL CELL

Transcription factor choice in the Hippo signaling pathway: homothorax and yorkie regulation of the microRNA bantam in the progenitor domain of the Drosophila eye imaginal disc

(2009) H. W. Peng et al.   GENES & DEVELOPMENT

KLF4 and PBX1 Directly RegulateNANOGExpression in Human Embryonic Stem Cells

(2009) Ken Kwok-Keung Chan et al.   STEM CELLS

Variation in Homeodomain DNA Binding Revealed by High-Resolution Analysis of Sequence Preferences

(2008) Michael F. Berger et al.   CELL

Analysis of Homeodomain Specificities Allows the Family-wide Prediction of Preferred Recognition Sites

(2008) Marcus B. Noyes et al.   CELL