Role of the OTUB1 / IRF7 / NOX4 axis in oxidative stress injury and inflammatory responses in mice with Parkinson's disease

MicroRNA-181a–2–3p shuttled by mesenchymal stem cell-secreted extracellular vesicles inhibits oxidative stress in Parkinson’s disease by inhibiting EGR1 and NOX4

(2022) Jianjun Ma et al.   Cell Death Discovery

An Overview of Oxidative Stress, Neuroinflammation, and Neurodegenerative Diseases

(2022) Daniel Mihai Teleanu et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Reduction in Nesfatin-1 Levels in the Cerebrospinal Fluid and Increased Nigrostriatal Degeneration Following Ventricular Administration of Anti-nesfatin-1 Antibody in Mice

(2021) Huanhuan Chen et al.   Frontiers in Neuroscience

The functions and regulation of Otubains in protein homeostasis and diseases

(2021) Qiong Zhu et al.   AGEING RESEARCH REVIEWS

Potential role of cannabidiol in Parkinson’s disease by targeting the WNT/β-catenin pathway, oxidative stress and inflammation

(2021) Alexandre Vallée et al.   Aging-US

Parkinson's disease

(2021) Bastiaan R Bloem et al.   LANCET

MEKK3 activates IRF7 to trigger a potent type I interferon induction in response to TLR7/9 signaling

(2021) Miaomiao Cai et al.   MOLECULAR IMMUNOLOGY

Cellular nucleic acid–binding protein is essential for type I interferon–mediated immunity to RNA virus infection

(2021) Yongzhi Chen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Melatonin Attenuates Neuroinflammation by Down-Regulating NLRP3 Inflammasome via a SIRT1-Dependent Pathway in MPTP-Induced Models of Parkinson’s Disease

(2021) Ran Zheng et al.   Journal of Inflammation Research

The role of interferon regulatory factor 7 in the pathogenicity and immunogenicity of rabies virus in a mouse model

(2021) Caiqian Wang et al.   JOURNAL OF GENERAL VIROLOGY

JASPAR 2022: the 9th release of the open-access database of transcription factor binding profiles

(2021) Jaime A Castro-Mondragon et al.   NUCLEIC ACIDS RESEARCH

The deubiquitinase OTUB1 augments NF-κB-dependent immune responses in dendritic cells in infection and inflammation by stabilizing UBC13

(2020) Floriana Mulas et al.   Cellular & Molecular Immunology

Diagnosis and Treatment of Parkinson Disease

(2020) Melissa J. Armstrong et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Amyloid aggregates of the deubiquitinase OTUB1 are neurotoxic, suggesting that they contribute to the development of Parkinson’s disease

(2020) Raniki Kumari et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Genetic variability of inflammation and oxidative stress genes does not play a major role in the occurrence of adverse events of dopaminergic treatment in Parkinson’s disease

(2019) Sara Redenšek et al.   Journal of Neuroinflammation

The Role of NOX4 in Parkinson’s Disease with Dementia

(2019) Dong-Hee Choi et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Transcriptome sequencing in a 6-hydroxydopamine rat model of Parkinson’s disease

(2019) Jia Li et al.   GENES & GENETIC SYSTEMS

Oxidative stress in the aging substantia nigra and the etiology of Parkinson's disease

(2019) Benjamin G. Trist et al.   AGING CELL

Alzheimer’s Disease, Oligomers, and Inflammation

(2018) Gianluigi Forloni et al.   JOURNAL OF ALZHEIMERS DISEASE

Mangiferin and Morin Attenuate Oxidative Stress, Mitochondrial Dysfunction, and Neurocytotoxicity, Induced by Amyloid Beta Oligomers

(2018) Elena Alberdi et al.   Oxidative Medicine and Cellular Longevity

Moderate-Intensity Exercise Induces Neurogenesis and Improves Cognition in Old Mice by Upregulating Hippocampal Hippocalcin, Otub1, and Spectrin-α

(2018) Ji Hyun Kim et al.   MOLECULAR NEUROBIOLOGY

Post-translational modifications of Parkinson's disease-related proteins: Phosphorylation, SUMOylation and Ubiquitination

(2018) Stella C. Junqueira et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

The Role of NADPH Oxidases and Oxidative Stress in Neurodegenerative Disorders

(2018) Anuradha Tarafdar et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Parkinson Disease

(2018) Stephen G. Reich et al.   MEDICAL CLINICS OF NORTH AMERICA

Type-1 interferons contribute to the neuroinflammatory response and disease progression of the MPTP mouse model of Parkinson's disease

(2016) Bevan S. Main et al.   GLIA

OTUB1 attenuates neuronal apoptosis after intracerebral hemorrhage

(2016) Lili Xie et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

Mechanisms Underlying Interferon-γ-Induced Priming of Microglial Reactive Oxygen Species Production

(2016) Nicholas G. Spencer et al.   PLoS One

New Insights on NOX Enzymes in the Central Nervous System

(2013) Zeynab Nayernia et al.   ANTIOXIDANTS & REDOX SIGNALING

IRF7: activation, regulation, modification and function

(2011) S Ning et al.   GENES AND IMMUNITY

Requirement of NOX2 and Reactive Oxygen Species for Efficient RIG-I-Mediated Antiviral Response through Regulation of MAVS Expression

(2010) Anton Soucy-Faulkner et al.   PLoS Pathogens

Structural basis and specificity of human otubain 1-mediated deubiquitination

(2008) Mariola J. Edelmann et al.   BIOCHEMICAL JOURNAL