Parkinson's disease

Diagnosis and Treatment of Parkinson Disease

(2020) Melissa J. Armstrong et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

β-adrenoreceptors and the risk of Parkinson's disease

(2020) Franziska Hopfner et al.   LANCET NEUROLOGY

Ambroxol for the Treatment of Patients With Parkinson Disease With and Without Glucocerebrosidase Gene Mutations

(2020) Stephen Mullin et al.   JAMA Neurology

Comparison of Integrated Outpatient Palliative Care With Standard Care in Patients With Parkinson Disease and Related Disorders

(2020) Benzi M. Kluger et al.   JAMA Neurology

Integrated and patient-centred management of Parkinson's disease: a network model for reshaping chronic neurological care

(2020) Bastiaan R Bloem et al.   LANCET NEUROLOGY

Outcome of Parkinson's Disease Patients Affected by COVID ‐19

(2020) Angelo Antonini et al.   MOVEMENT DISORDERS

Disruption of cellular proteostasis by H1N1 influenza A virus causes α-synuclein aggregation

(2020) Rita Marreiros et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Impact of the COVID-19 Pandemic on Parkinson’s Disease: Hidden Sorrows and Emerging Opportunities

(2020) Rick C. Helmich et al.   Journal of Parkinsons Disease

COVID ‐19 in Parkinson’s Disease Patients Living in Lombardy, Italy

(2020) Alfonso Fasano et al.   MOVEMENT DISORDERS

In vivo distribution of α-synuclein in multiple tissues and biofluids in Parkinson disease

(2020) Lana M. Chahine et al.   NEUROLOGY

Screening of Parkinsonian subtle fine-motor impairment from touchscreen typing via deep learning

(2020) Dimitrios Iakovakis et al.   Scientific Reports

Optimizing Treatment in Undertreated Late-Stage Parkinsonism: A Pragmatic Randomized Trial

(2020) Adrianus L.A.J. Hommel et al.   Journal of Parkinsons Disease

Brain-first versus body-first Parkinson’s disease: a multimodal imaging case-control study

(2020) Jacob Horsager et al.   BRAIN

A case of probable Parkinson's disease after SARS-CoV-2 infection

(2020) Mikhal E Cohen et al.   LANCET NEUROLOGY

Is COVID-19 a Perfect Storm for Parkinson’s Disease?

(2020) Patrik Brundin et al.   TRENDS IN NEUROSCIENCES

The burden of neurological diseases in Europe: an analysis for the Global Burden of Disease Study 2017

(2020) Günther Deuschl et al.   Lancet Public Health

The Rostock International Parkinson's Disease ( ROPAD ) Study: Protocol and Initial Findings

(2020) Volha Skrahina et al.   MOVEMENT DISORDERS

SARS-CoV-2 and the risk of Parkinson's disease: facts and fantasy

(2020) Marcelo Merello et al.   LANCET NEUROLOGY

The association between lifestyle factors and Parkinson's disease progression and mortality

(2019) Kimberly C. Paul et al.   MOVEMENT DISORDERS

Update on treatments for nonmotor symptoms of Parkinson's disease-an evidence-based medicine review

(2019) Klaus Seppi et al.   MOVEMENT DISORDERS

Diagnostic delay in Parkinson's disease caused by PRKN mutations

(2019) Marta Ruiz-Lopez et al.   PARKINSONISM & RELATED DISORDERS

Gut bacterial tyrosine decarboxylases restrict levels of levodopa in the treatment of Parkinson’s disease

(2019) Sebastiaan P. van Kessel et al.   Nature Communications

Prognosis and Neuropathologic Correlation of Clinical Subtypes of Parkinson Disease

(2019) Eduardo De Pablo-Fernández et al.   JAMA Neurology

Compensation Strategies for Gait Impairments in Parkinson Disease

(2019) Jorik Nonnekes et al.   JAMA Neurology

Randomized Delayed-Start Trial of Levodopa in Parkinson’s Disease

(2019) Constant V.M. Verschuur et al.   NEW ENGLAND JOURNAL OF MEDICINE

Randomized trial of care management to improve Parkinson disease care quality

(2019) Karen I. Connor et al.   NEUROLOGY

Serum NFL discriminates Parkinson disease from atypical parkinsonisms

(2019) Tainá M. Marques et al.   NEUROLOGY

Predicting diagnosis of Parkinson's disease: A risk algorithm based on primary care presentations

(2019) Anette Schrag et al.   MOVEMENT DISORDERS

Global, regional, and national burden of neurological disorders, 1990–2016: a systematic analysis for the Global Burden of Disease Study 2016

(2019) Valery L Feigin et al.   LANCET NEUROLOGY

Safety and efficacy of CVT-301 (levodopa inhalation powder) on motor function during off periods in patients with Parkinson's disease: a randomised, double-blind, placebo-controlled phase 3 trial

(2019) Peter A LeWitt et al.   LANCET NEUROLOGY

Risk and predictors of dementia and parkinsonism in idiopathic REM sleep behaviour disorder: a multicentre study

(2019) Ronald B Postuma et al.   BRAIN

Randomized trial of intermittent intraputamenal glial cell line-derived neurotrophic factor in Parkinson’s disease

(2019) Alan Whone et al.   BRAIN

Ambroxol as a novel disease-modifying treatment for Parkinson’s disease dementia: protocol for a single-centre, randomized, double-blind, placebo-controlled trial

(2019) C. R. A. Silveira et al.   BMC Neurology

Evolution of prodromal Parkinson’s disease and dementia with Lewy bodies: a prospective study

(2019) Seyed-Mohammad Fereshtehnejad et al.   BRAIN

Effects of Mindfulness Yoga vs Stretching and Resistance Training Exercises on Anxiety and Depression for People With Parkinson Disease

(2019) Jojo Y. Y. Kwok et al.   JAMA Neurology

Using global team science to identify genetic Parkinson's disease worldwide

(2019) Eva‐Juliane Vollstedt et al.   ANNALS OF NEUROLOGY

The PRIAMO study: active sexual life is associated with better motor and non‐motor outcomes in men with early Parkinson's disease

(2019) M. Picillo et al.   EUROPEAN JOURNAL OF NEUROLOGY

Parkinson's disease in the Western Pacific Region

(2019) Shen-Yang Lim et al.   LANCET NEUROLOGY

Randomized phase I clinical trial of anti–α‐synuclein antibody BIIB054

(2019) Miroslaw Brys et al.   MOVEMENT DISORDERS

Magnetic Resonance Imaging–Visible Perivascular Spaces in Basal Ganglia Predict Cognitive Decline in Parkinson's Disease

(2019) Yae Won Park et al.   MOVEMENT DISORDERS

Intestinal infection triggers Parkinson’s disease-like symptoms in Pink1−/− mice

(2019) Diana Matheoud et al.   NATURE

Designing stem-cell-based dopamine cell replacement trials for Parkinson’s disease

(2019) Roger A. Barker et al.   NATURE MEDICINE

Lewy pathology in Parkinson’s disease consists of crowded organelles and lipid membranes

(2019) Sarah H. Shahmoradian et al.   NATURE NEUROSCIENCE

Non-motor symptoms burden, mood, and gait problems are the most significant factors contributing to a poor quality of life in non-demented Parkinson's disease patients: Results from the COPPADIS Study Cohort

(2019) García D. Santos et al.   PARKINSONISM & RELATED DISORDERS

Temporal evolution of beta bursts in the parkinsonian cortical and basal ganglia network

(2019) Hayriye Cagnan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Discovery and inhibition of an interspecies gut bacterial pathway for Levodopa metabolism

(2019) Vayu Maini Rekdal et al.   SCIENCE

The Qualification of an Enrichment Biomarker for Clinical Trials Targeting Early Stages of Parkinson’s Disease

(2019) Diane Stephenson et al.   Journal of Parkinsons Disease

GBA1-associated parkinsonism

(2019) Emory Ryan et al.   CURRENT OPINION IN NEUROLOGY

Enhancing glycolysis attenuates Parkinson’s disease progression in models and clinical databases

(2019) Rong Cai et al.   JOURNAL OF CLINICAL INVESTIGATION

Update of the MDS research criteria for prodromal Parkinson's disease

(2019) Sebastian Heinzel et al.   MOVEMENT DISORDERS

The Movement Disorder Society Nonmotor Rating Scale: Initial Validation Study

(2019) K. Ray Chaudhuri et al.   MOVEMENT DISORDERS

Blood NfL

(2019) Chin-Hsien Lin et al.   NEUROLOGY

Quadruple Decision Making for Parkinson’s Disease Patients: Combining Expert Opinion, Patient Preferences, Scientific Evidence, and Big Data Approaches to Reach Precision Medicine

(2019) Lieneke van den Heuvel et al.   Journal of Parkinsons Disease

Effects of dance therapy on cognitive and mood symptoms in people with Parkinson's disease: A systematic review and meta-analysis

(2019) Qi Zhang et al.   Complementary Therapies in Clinical Practice

Occupational exposure to chronic ionizing radiation increases risk of Parkinson's disease incidence in Russian Mayak workers

(2019) Tamara V Azizova et al.   INTERNATIONAL JOURNAL OF EPIDEMIOLOGY

Effectiveness of home-based and remotely supervised aerobic exercise in Parkinson's disease: a double-blind, randomised controlled trial

(2019) Nicolien M van der Kolk et al.   LANCET NEUROLOGY

CSF or serum neurofilament light added to α‐Synuclein panel discriminates Parkinson's from controls

(2019) Linda P. Oosterveld et al.   MOVEMENT DISORDERS

The Parkinson's Disease Mendelian Randomization Research Portal

(2019) Alastair J. Noyce et al.   MOVEMENT DISORDERS

Neurodegenerative Disease Mortality among Former Professional Soccer Players

(2019) Daniel F. Mackay et al.   NEW ENGLAND JOURNAL OF MEDICINE

Physiotherapy improves motor function in patients with the Parkinson variant of multiple system atrophy: A prospective trial

(2019) C. Raccagni et al.   PARKINSONISM & RELATED DISORDERS

Levodopa response in later stages of Parkinson's disease: A case-control study

(2019) Margherita Fabbri et al.   PARKINSONISM & RELATED DISORDERS

Patient and caregiver characteristics associated with caregiver burden in Parkinson’s disease: a palliative care approach

(2019) Zachary A. Macchi et al.   Annals of Palliative Medicine

Apomorphine sublingual film for off episodes in Parkinson's disease: a randomised, double-blind, placebo-controlled phase 3 study

(2019) C Warren Olanow et al.   LANCET NEUROLOGY

Identification of novel risk loci, causal insights, and heritable risk for Parkinson's disease: a meta-analysis of genome-wide association studies

(2019) Mike A Nalls et al.   LANCET NEUROLOGY

Nilotinib Effects on Safety, Tolerability, and Potential Biomarkers in Parkinson Disease

(2019) Fernando. L. Pagan et al.   JAMA Neurology

Plasma urate and risk of Parkinson's disease: a Mendelian randomization study

(2018) Camilla J Kobylecki et al.   ANNALS OF NEUROLOGY

Professional occupation and the risk of Parkinson Disease

(2018) Sirwan K L Darweesh et al.   EUROPEAN JOURNAL OF NEUROLOGY

Patient-centered integrated healthcare improves quality of life in Parkinson’s disease patients: a randomized controlled trial

(2018) Carsten Eggers et al.   JOURNAL OF NEUROLOGY

Neurological diseases and risk of suicide attempt: a case–control study

(2018) Astrid Eliasen et al.   JOURNAL OF NEUROLOGY

Interdisciplinary Home Visits for Individuals with Advanced Parkinson's Disease and Related Disorders

(2018) Jori Fleisher et al.   JOURNAL OF THE AMERICAN GERIATRICS SOCIETY

MPTP-induced parkinsonism: an historical case series

(2018) Jorik Nonnekes et al.   LANCET NEUROLOGY

Focused ultrasound subthalamotomy in patients with asymmetric Parkinson's disease: a pilot study

(2018) Raul Martínez-Fernández et al.   LANCET NEUROLOGY

Effectiveness and costs of specialised physiotherapy given via ParkinsonNet: a retrospective analysis of medical claims data

(2018) Jan H L Ypinga et al.   LANCET NEUROLOGY

Genotype-Phenotype Relations for the Parkinson's Disease Genes Parkin , PINK1 , DJ1: MDSGene Systematic Review

(2018) Meike Kasten et al.   MOVEMENT DISORDERS

Long-term safety and efficacy of levodopa-carbidopa intestinal gel in advanced Parkinson's disease

(2018) Hubert H. Fernandez et al.   MOVEMENT DISORDERS

Sex disparities in health and health care utilization after Parkinson diagnosis: Rethinking PD associated disability

(2018) Michelle E. Fullard et al.   PARKINSONISM & RELATED DISORDERS

Clinical correlates of cerebral white matter abnormalities in patients with Parkinson's disease

(2018) Bibet L. ten Harmsen et al.   PARKINSONISM & RELATED DISORDERS

Gait characteristics and falls in Parkinson's disease: A systematic review and meta-analysis

(2018) Mark W. Creaby et al.   PARKINSONISM & RELATED DISORDERS

Precision Medicine in Parkinson’s Disease – Exploring Patient-Initiated Self-Tracking

(2018) Sara Riggare et al.   Journal of Parkinsons Disease

Using Smartphones and Machine Learning to Quantify Parkinson Disease Severity

(2018) Andong Zhan et al.   JAMA Neurology

Effect of High-Intensity Treadmill Exercise on Motor Symptoms in Patients With De Novo Parkinson Disease

(2018) Margaret Schenkman et al.   JAMA Neurology

Office-Based Screening for Dementia in Parkinson Disease

(2018) Benjamin K. Dawson et al.   JAMA Neurology

Parkinson’s disease: evolution of cognitive impairment and CSF Aβ1–42 profiles in a prospective longitudinal study

(2018) Stefanie Lerche et al.   JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY

Apomorphine subcutaneous infusion in patients with Parkinson's disease with persistent motor fluctuations (TOLEDO): a multicentre, double-blind, randomised, placebo-controlled trial

(2018) Regina Katzenschlager et al.   LANCET NEUROLOGY

Speech treatment in Parkinson's disease: Randomized controlled trial (RCT)

(2018) Lorraine Ramig et al.   MOVEMENT DISORDERS

Parkin and PINK1 mitigate STING-induced inflammation

(2018) Danielle A. Sliter et al.   NATURE

Comprehensive Examination of Therapies for Pain in Parkinson’s Disease: A Systematic Review and Meta-Analysis

(2018) Abdul Rehman Qureshi et al.   NEUROEPIDEMIOLOGY

MRIgFUS in tremor-dominant PD does not lead to substantial cognitive adverse events

(2018) Thomas M. Zervos et al.   NEUROLOGY

Focused ultrasound thalamotomy in Parkinson disease

(2018) Scott A. Sperling et al.   NEUROLOGY

Smartphone motor testing to distinguish idiopathic REM sleep behavior disorder, controls, and PD

(2018) Siddharth Arora et al.   NEUROLOGY

Frequency of Loss of Function Variants in LRRK2 in Parkinson Disease

(2018) Cornelis Blauwendraat et al.   JAMA Neurology

PINK1-dependent mitophagy is driven by the UPS and can occur independently of LC3 conversion

(2018) Aleksandar Rakovic et al.   CELL DEATH AND DIFFERENTIATION

The Linked Clinical Trials initiative (LCT) for Parkinson's disease

(2018) Patrik Brundin et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Global, regional, and national burden of Parkinson's disease, 1990–2016: a systematic analysis for the Global Burden of Disease Study 2016

(2018) E. Ray Dorsey et al.   LANCET NEUROLOGY

Importance of low diagnostic Accuracy for early Parkinson's disease

(2018) Thomas G. Beach et al.   MOVEMENT DISORDERS

Survival rates among Parkinson's disease patients who carry mutations in the LRRK2 and GBA genes

(2018) Avner Thaler et al.   MOVEMENT DISORDERS

Baseline predictors for progression 4 years after Parkinson's disease diagnosis in the De Novo Parkinson Cohort (DeNoPa)

(2018) Brit Mollenhauer et al.   MOVEMENT DISORDERS

Mediterranean diet adherence is related to reduced probability of prodromal Parkinson's disease

(2018) Maria I. Maraki et al.   MOVEMENT DISORDERS

Underrepresentation of women in Parkinson's disease trials

(2018) Anouk Tosserams et al.   MOVEMENT DISORDERS

Utility and implications of exome sequencing in early‐onset Parkinson's disease

(2018) Joanne Trinh et al.   MOVEMENT DISORDERS

Genotype-phenotype relations for the Parkinson's disease genes SNCA, LRRK2, VPS35: MDSGene systematic review

(2018) Joanne Trinh et al.   MOVEMENT DISORDERS

Early predictors of mortality in parkinsonism and Parkinson disease

(2018) David Bäckström et al.   NEUROLOGY

Poly(ADP-ribose) drives pathologic α-synuclein neurodegeneration in Parkinson’s disease

(2018) Tae-In Kam et al.   SCIENCE

The Emerging Evidence of the Parkinson Pandemic

(2018) E. Ray Dorsey et al.   Journal of Parkinsons Disease

Comorbid conditions associated with Parkinson's disease: A longitudinal and comparative study with Alzheimer disease and control subjects

(2017) D. Santos García et al.   JOURNAL OF THE NEUROLOGICAL SCIENCES

Exenatide once weekly versus placebo in Parkinson's disease: a randomised, double-blind, placebo-controlled trial

(2017) Dilan Athauda et al.   LANCET

Prediction of cognition in Parkinson's disease with a clinical–genetic score: a longitudinal analysis of nine cohorts

(2017) Ganqiang Liu et al.   LANCET NEUROLOGY

Clinical variables and biomarkers in prediction of cognitive impairment in patients with newly diagnosed Parkinson's disease: a cohort study

(2017) Anette Schrag et al.   LANCET NEUROLOGY

Development and validation of prognostic survival models in newly diagnosed Parkinson's disease

(2017) Angus D. Macleod et al.   MOVEMENT DISORDERS

Training dual tasks together or apart in Parkinson's disease: Results from the DUALITY trial

(2017) Carolien Strouwen et al.   MOVEMENT DISORDERS

Projection of the prevalence of Parkinson's disease in the coming decades: Revisited

(2017) Alexander Rossi et al.   MOVEMENT DISORDERS

T cells from patients with Parkinson’s disease recognize α-synuclein peptides

(2017) David Sulzer et al.   NATURE

Utilization of rehabilitation therapy services in Parkinson disease in the United States

(2017) Michelle E. Fullard et al.   NEUROLOGY

National randomized controlled trial of virtual house calls for Parkinson disease

(2017) Christopher A. Beck et al.   NEUROLOGY

Beliefs, knowledge and attitudes towards Parkinson's disease among a Xhosa speaking black population in South Africa: A cross-sectional study

(2017) Jolynne Mokaya et al.   PARKINSONISM & RELATED DISORDERS

Gender effect on non-motor symptoms in Parkinson's disease: are men more at risk?

(2017) A. Nicoletti et al.   PARKINSONISM & RELATED DISORDERS

Feasibility of large-scale deployment of multiple wearable sensors in Parkinson's disease

(2017) Ana Lígia Silva de Lima et al.   PLoS One

Dopamine oxidation mediates mitochondrial and lysosomal dysfunction in Parkinson’s disease

(2017) Lena F. Burbulla et al.   SCIENCE

Biological and Clinical Implications of Comorbidities in Parkinson’s Disease

(2017) Jose A. Santiago et al.   Frontiers in Aging Neuroscience

Timed Light Therapy for Sleep and Daytime Sleepiness Associated With Parkinson Disease

(2017) Aleksandar Videnovic et al.   JAMA Neurology

Safety and Efficacy of Focused Ultrasound Thalamotomy for Patients With Medication-Refractory, Tremor-Dominant Parkinson Disease

(2017) Aaron E. Bond et al.   JAMA Neurology

Gut Microbiota Regulate Motor Deficits and Neuroinflammation in a Model of Parkinson’s Disease

(2016) Timothy R. Sampson et al.   CELL

Addition of a non-immersive virtual reality component to treadmill training to reduce fall risk in older adults (V-TIME): a randomised controlled trial

(2016) Anat Mirelman et al.   LANCET

Longitudinal Measurements of Cerebrospinal Fluid Biomarkers in Parkinson's Disease

(2016) Sara Hall et al.   MOVEMENT DISORDERS

Loss of independence in early Parkinson disease

(2016) Anders Bjornestad et al.   NEUROLOGY

Accuracy of clinical diagnosis of Parkinson disease

(2016) Giovanni Rizzo et al.   NEUROLOGY

Gender and non motor fluctuations in Parkinson's disease: A prospective study

(2016) Marina Picillo et al.   PARKINSONISM & RELATED DISORDERS

Risk and course of motor complications in a population-based incident Parkinson's disease cohort

(2016) Anders Bjornestad et al.   PARKINSONISM & RELATED DISORDERS

Non motor subtypes and Parkinson's disease

(2016) Anna Sauerbier et al.   PARKINSONISM & RELATED DISORDERS

Nilotinib Effects in Parkinson’s disease and Dementia with Lewy bodies

(2016) Fernando Pagan et al.   Journal of Parkinsons Disease

Dopaminergic modulation of motor network dynamics in Parkinson's disease

(2015) J. Michely et al.   BRAIN

Parkinson's disease

(2015) Lorraine V Kalia et al.   LANCET

Vascular Parkinsonism: Deconstructing a Syndrome

(2015) Joaquin A. Vizcarra et al.   MOVEMENT DISORDERS

MDS clinical diagnostic criteria for Parkinson's disease

(2015) Ronald B. Postuma et al.   MOVEMENT DISORDERS

The modern pre-levodopa era of Parkinson's disease: insights into motor complications from sub-Saharan Africa

(2014) R. Cilia et al.   BRAIN

Pharmacological Treatment of Parkinson Disease

(2014) Barbara S. Connolly et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Long-term effectiveness of dopamine agonists and monoamine oxidase B inhibitors compared with levodopa as initial treatment for Parkinson's disease (PD MED): a large, open-label, pragmatic randomised trial

(2014) PD MED Collaborative Group   LANCET

Efficacy of occupational therapy for patients with Parkinson's disease: a randomised controlled trial

(2014) Ingrid H W M Sturkenboom et al.   LANCET NEUROLOGY

The prevalence of Parkinson's disease: A systematic review and meta-analysis

(2014) Tamara Pringsheim et al.   MOVEMENT DISORDERS

GBA-associated Parkinson's disease: Reduced survival and more rapid progression in a prospective longitudinal study

(2014) Kathrin Brockmann et al.   MOVEMENT DISORDERS

Meta-analysis of early nonmotor features and risk factors for Parkinson disease

(2012) Alastair J. Noyce et al.   ANNALS OF NEUROLOGY

Gaucher Disease Glucocerebrosidase and α-Synuclein Form a Bidirectional Pathogenic Loop in Synucleinopathies

(2011) Joseph R. Mazzulli et al.   CELL

The patients' perception of prodromal symptoms before the initial diagnosis of Parkinson's disease

(2011) Alexandra Gaenslen et al.   MOVEMENT DISORDERS

Multicenter Analysis of Glucocerebrosidase Mutations in Parkinson's Disease

(2009) E. Sidransky et al.   NEW ENGLAND JOURNAL OF MEDICINE