Mangiferin and Morin Attenuate Oxidative Stress, Mitochondrial Dysfunction, and Neurocytotoxicity, Induced by Amyloid Beta Oligomers

Alzheimer's Disease and the Amyloid-β Peptide

(2017) M. Paul Murphy et al.   JOURNAL OF ALZHEIMERS DISEASE

The polyphenols resveratrol and epigallocatechin-3-gallate restore the severe impairment of mitochondria in hippocampal progenitor cells from a Down syndrome mouse model

(2016) Daniela Valenti et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Roselle Polyphenols Exert Potent Negative Inotropic Effects via Modulation of Intracellular Calcium Regulatory Channels in Isolated Rat Heart

(2016) Yi-Cheng Lim et al.   Cardiovascular Toxicology

Resveratrol Specifically Kills Cancer Cells by a Devastating Increase in the Ca2+ Coupling Between the Greatly Tethered Endoplasmic Reticulum and Mitochondria

(2016) Corina T. Madreiter-Sokolowski et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

Oxidative signature of cerebrospinal fluid from mild cognitive impairment and Alzheimer disease patients

(2016) Fabio Di Domenico et al.   FREE RADICAL BIOLOGY AND MEDICINE

Long-Term Mangiferin Extract Treatment Improves Central Pathology and Cognitive Deficits in APP/PS1 Mice

(2016) Carmen Infante-Garcia et al.   MOLECULAR NEUROBIOLOGY

Morin reverses neuropathological and cognitive impairments in APPswe/PS1dE9 mice by targeting multiple pathogenic mechanisms

(2016) Ying Du et al.   NEUROPHARMACOLOGY

Redox proteomics identification of specifically carbonylated proteins in the hippocampi of triple transgenic Alzheimer's disease mice at its earliest pathological stage

(2015) Liming Shen et al.   Journal of Proteomics

Soluble amyloid-β oligomers as synaptotoxins leading to cognitive impairment in Alzheimer’s disease

(2015) Sergio T. Ferreira et al.   Frontiers in Cellular Neuroscience

ROS Function in Redox Signaling and Oxidative Stress

(2014) Michael Schieber et al.   CURRENT BIOLOGY

Antioxidant Clinical Trials in Mild Cognitive Impairment and Alzheimer’s disease – Challenges and Perspectives

(2014) Maria Polidori et al.   CURRENT PHARMACEUTICAL DESIGN

CGP37157, an inhibitor of the mitochondrial Na+/Ca2+ exchanger, protects neurons from excitotoxicity by blocking voltage-gated Ca2+ channels

(2014) A Ruiz et al.   Cell Death & Disease

Mechanisms of Rapid Reactive Oxygen Species Generation in Response to Cytosolic Ca2+ or Zn2+ Loads in Cortical Neurons

(2013) Aaron Clausen et al.   PLoS One

Neuropathological Alterations in Alzheimer Disease

(2013) A. Serrano-Pozo et al.   Cold Spring Harbor Perspectives in Medicine

Protein carbonylation and metabolic control systems

(2012) Jessica M. Curtis et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Prolonged Exposure of Cortical Neurons to Oligomeric Amyloid-β Impairs NMDA Receptor Function Via NADPH Oxidase-Mediated ROS Production: Protective Effect of Green Tea (-)-Epigallocatechin-3-Gallate

(2011) Yan He et al.   ASN Neuro

Amyloid β peptide oligomers directly activate NMDA receptors

(2011) Laura Texidó et al.   CELL CALCIUM

Mangiferin attenuates methylmercury induced cytotoxicity against IMR-32, human neuroblastoma cells by the inhibition of oxidative stress and free radical scavenging potential

(2011) Shubhankar Das et al.   CHEMICO-BIOLOGICAL INTERACTIONS

Cross talk between mitochondria and NADPH oxidases

(2011) Sergey Dikalov   FREE RADICAL BIOLOGY AND MEDICINE

The Mitochondria-Targeted Antioxidant MitoQ Prevents Loss of Spatial Memory Retention and Early Neuropathology in a Transgenic Mouse Model of Alzheimer's Disease

(2011) M. J. McManus et al.   JOURNAL OF NEUROSCIENCE

Morin attenuates tau hyperphosphorylation by inhibiting GSK3β

(2011) Eun Ji Gong et al.   NEUROBIOLOGY OF DISEASE

Amyloid β oligomers induce Ca2+ dysregulation and neuronal death through activation of ionotropic glutamate receptors

(2010) Elena Alberdi et al.   CELL CALCIUM

Structural conversion of neurotoxic amyloid-β1–42 oligomers to fibrils

(2010) Mahiuddin Ahmed et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Oxidatively modified proteins in Alzheimer’s disease (AD), mild cognitive impairment and animal models of AD: role of Abeta in pathogenesis

(2009) Rukhsana Sultana et al.   ACTA NEUROPATHOLOGICA

Molecular mechanisms of neuroprotection by two natural antioxidant polyphenols

(2009) María Rosario Campos-Esparza et al.   CELL CALCIUM

DNA Damage and Repair in Alzheimers Disease

(2009) Fabio Coppede et al.   Current Alzheimer Research

Inhibitors of Cytochrome c Release with Therapeutic Potential for Huntington's Disease

(2008) X. Wang et al.   JOURNAL OF NEUROSCIENCE

Cyclophilin D deficiency attenuates mitochondrial and neuronal perturbation and ameliorates learning and memory in Alzheimer's disease

(2008) Heng Du et al.   NATURE MEDICINE

Oxidatively modified RNA in mild cognitive impairment

(2007) Mark A. Lovell et al.   NEUROBIOLOGY OF DISEASE