Lactoferrin modification of berberine nanoliposomes enhances the neuroprotective effects in a mouse model of Alzheimer’s disease

(D-Ser2) oxyntomodulin recovers hippocampal synaptic structure and theta rhythm in Alzheimer’s disease transgenic mice

(2022) Jin-Shun Qi et al.   Neural Regeneration Research

Action Mechanisms of Curcumin in Alzheimer’s Disease and Its Brain Targeted Delivery

(2021) Duygu Ege   Materials

Liposome based drug delivery as a potential treatment option for Alzheimer’s disease

(2021) Surabhi Shukla et al.   Neural Regeneration Research

Brain microRNAs dysregulation: implication for missplicing and abnormal post-translational modifications of tau protein in Alzheimer’s disease and related tauopathies

(2020) Maryam Bazrgar et al.   PHARMACOLOGICAL RESEARCH

Ligand conjugated targeted nanotherapeutics for treatment of neurological disorders

(2020) Saurabh Mittal et al.   CURRENT PHARMACEUTICAL DESIGN

Biological properties and clinical applications of berberine

(2020) Danyang Song et al.   Frontiers of Medicine

The ARRIVE guidelines 2.0: Updated guidelines for reporting animal research

(2020) Nathalie Percie du Sert et al.   PLOS BIOLOGY

Drug repositioning and repurposing for Alzheimer disease

(2020) Clive Ballard et al.   Nature Reviews Neurology

Berberine-Loaded Liposomes for the Treatment of Leishmania infantum-Infected BALB/c Mice

(2020) Alba Calvo et al.   Pharmaceutics

Involvement of endoplasmic reticulum stress in amyloid β (1-42)-induced Alzheimer’s like neuropathological process in rat brain

(2020) Poonam Goswami et al.   BRAIN RESEARCH BULLETIN

Drug Development for Psychotropic, Cognitive-Enhancing, and Disease-Modifying Treatments for Alzheimer’s Disease

(2020) Jeffrey Cummings   JOURNAL OF NEUROPSYCHIATRY AND CLINICAL NEUROSCIENCES

Neuropharmacokinetic Evaluation of Lactoferrin-Treated Indinavir-Loaded Nanoemulsions: Remarkable Brain Delivery Enhancement

(2019) Zahra Karami et al.   DRUG DEVELOPMENT AND INDUSTRIAL PHARMACY

Neuroprotective effects of berberine in animal models of Alzheimer’s disease: a systematic review of pre-clinical studies

(2019) Ning-Ning Yuan et al.   BMC Complementary and Alternative Medicine

Natural silibinin modulates amyloid precursor protein processing and amyloid-β protein clearance in APP/PS1 mice

(2019) Dafeng Bai et al.   Journal of Physiological Sciences

Lactoferrin Coupled Lower Generation PAMAM Dendrimers for Brain Targeted Delivery of Memantine in Aluminum-Chloride-Induced Alzheimer’s Disease in Mice

(2019) Avinash Gothwal et al.   BIOCONJUGATE CHEMISTRY

Therapeutic potential and recent delivery systems of berberine: A wonder molecule

(2019) Marina Raju et al.   Journal of Functional Foods

Receptor specific, stimuli responsive and subcellular targeted approaches for effective therapy of Alzheimer: Role of surface engineered nanocarriers

(2019) Divya Gopalan et al.   JOURNAL OF CONTROLLED RELEASE

Diabetes mellitus and Alzheimer’s disease: GSK-3β as a potential link

(2018) Ying Zhang et al.   BEHAVIOURAL BRAIN RESEARCH

Nano strategies for berberine delivery, a natural alkaloid of Berberis

(2018) Elaheh Mirhadi et al.   BIOMEDICINE & PHARMACOTHERAPY

Estrogen-related receptor alpha is involved in Alzheimer's disease-like pathology

(2018) Ying Tang et al.   EXPERIMENTAL NEUROLOGY

Lactoferrin-modified rotigotine nanoparticles for enhanced nose-to-brain delivery: LESA-MS/MS-based drug biodistribution, pharmacodynamics, and neuroprotective effects

(2018) Xiuju Yan et al.   International Journal of Nanomedicine

Intranasal delivery of Huperzine A to the brain using lactoferrin-conjugated N-trimethylated chitosan surface-modified PLGA nanoparticles for treatment of Alzheimer’s disease

(2018) Qingqing Meng et al.   International Journal of Nanomedicine

Design of lactoferrin modified lipid nano-carriers for efficient brain-targeted delivery of nimodipine

(2018) Chaoyue Zhao et al.   Materials Science & Engineering C-Materials for Biological Applications

PEGylated hyaluronic acid-coated liposome for enhanced in vivo efficacy of sorafenib via active tumor cell targeting and prolonged systemic exposure

(2018) Lingxuan Mo et al.   Nanomedicine-Nanotechnology Biology and Medicine

Fluorescence Imaging of Alzheimer's Disease with a Flat Ensemble Formed between a Quinoline-Malononitrile AIEgen and Thin-Layer Molybdenum Disulfide

(2018) Wei-Tao Dou et al.   CHEMBIOCHEM

Berberine ameliorates lipopolysaccharide-induced learning and memory deficit in the rat: insights into underlying molecular mechanisms

(2018) Sepideh Sadraie et al.   METABOLIC BRAIN DISEASE

Antitumor efficacy of Lf modified daunorubicin plus honokiol liposomes in treatment of brain glioma

(2017) Shuang Liu et al.   EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES

Berberine improves cognitive impairment by promoting autophagic clearance and inhibiting production of β-amyloid in APP/tau/PS1 mouse model of Alzheimer's disease

(2017) Min Huang et al.   EXPERIMENTAL GERONTOLOGY

Recent advancements in liposomes targeting strategies to cross blood-brain barrier (BBB) for the treatment of Alzheimer's disease

(2017) Mukta Agrawal et al.   JOURNAL OF CONTROLLED RELEASE

Liposome encapsulated berberine treatment attenuates cardiac dysfunction after myocardial infarction

(2017) Iris E. Allijn et al.   JOURNAL OF CONTROLLED RELEASE

Preparation, pharmacokinetics and tumour-suppressive activity of berberine liposomes

(2017) Xinghui Wang et al.   JOURNAL OF PHARMACY AND PHARMACOLOGY

Caspase-3-dependent cleavage of Akt modulates tau phosphorylation via GSK3β kinase: implications for Alzheimer’s disease

(2017) J Chu et al.   MOLECULAR PSYCHIATRY

Berberine attenuates cognitive impairment and ameliorates tau hyperphosphorylation by limiting the self-perpetuating pathogenic cycle between NF-κB signaling, oxidative stress and neuroinflammation

(2017) Wenbo He et al.   Pharmacological Reports

Berberine Ameliorates Diabetes-Associated Cognitive Decline through Modulation of Aberrant Inflammation Response and Insulin Signaling Pathway in DM Rats

(2017) Qingjie Chen et al.   Frontiers in Pharmacology

Alzheimer's disease: Targeting the Cholinergic System

(2016) Talita H. Ferreira-Vieira et al.   Current Neuropharmacology

Old and new acetylcholinesterase inhibitors for Alzheimer’s disease

(2016) Daniela Galimberti et al.   EXPERT OPINION ON INVESTIGATIONAL DRUGS

Silibinin rescues learning and memory deficits by attenuating microglia activation and preventing neuroinflammatory reactions in SAMP8 mice

(2016) Ge Jin et al.   NEUROSCIENCE LETTERS

Berberine protects against memory impairment and anxiogenic-like behavior in rats submitted to sporadic Alzheimer’s-like dementia: Involvement of acetylcholinesterase and cell death

(2016) Juliana Sorraila de Oliveira et al.   NEUROTOXICOLOGY

New Developments in Liposomal Drug Delivery

(2015) Bhushan S. Pattni et al.   CHEMICAL REVIEWS

In vivo rapid fluorescence imaging of Alzheimer’s disease through accurate target bio-marking of zinc gluconate

(2015) Lanmei Lai et al.   Science Bulletin

Xanthoceraside Ameliorates Mitochondrial Dysfunction Contributing to the Improvement of Learning and Memory Impairment in Mice with Intracerebroventricular Injection of Aβ1-42

(2014) Xue-Fei Ji et al.   Evidence-based Complementary and Alternative Medicine

In Vitro and in Vivo Evaluation of Lactoferrin-Conjugated Liposomes as a Novel Carrier to Improve the Brain Delivery

(2013) Feng-Yun Huang et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Preparation of berberine hydrochloride long-circulating liposomes by ionophore A23187-mediated ZnSO4 gradient method

(2013) Xiang Luo et al.   Asian Journal of Pharmaceutical Sciences

Optimizing manufacture of liposomal berberine with evaluation of its antihepatoma effects in a murine xenograft model

(2012) Yung-Chang Lin et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

NIH Image to ImageJ: 25 years of image analysis

(2012) Caroline A Schneider et al.   NATURE METHODS

Berberine ameliorates β-amyloid pathology, gliosis, and cognitive impairment in an Alzheimer's disease transgenic mouse model

(2012) Siva Sundara Kumar Durairajan et al.   NEUROBIOLOGY OF AGING

Advances in the Pathogenesis of Alzheimer’s Disease: Focusing on Tau-Mediated Neurodegeneration

(2012) Yale Duan et al.   Translational Neurodegeneration

Fas-mediated neutrophil apoptosis is accelerated by Bid, Bak, and Bax and inhibited by Bcl-2 and Mcl-1

(2011) Ben A. Croker et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Highly Sensitive Protein Concentration Assay over a Wide Range via Surface-Enhanced Raman Scattering of Coomassie Brilliant Blue

(2010) Xiao Xia Han et al.   ANALYTICAL CHEMISTRY

Ethanol injection method for hydrophilic and lipophilic drug-loaded liposome preparation

(2009) Chiraz Jaafar-Maalej et al.   JOURNAL OF LIPOSOME RESEARCH

Conformation-activity studies on the interaction of berberine with acetylcholinesterase: Physical chemistry approach

(2009) Jin Xiang et al.   Progress in Natural Science-Materials International