Caspase-3-dependent cleavage of Akt modulates tau phosphorylation via GSK3β kinase: implications for Alzheimer’s disease

Importance of the Caspase Cleavage Site in Amyloid-β Protein Precursor

(2017) Dale E. Bredesen et al.   JOURNAL OF ALZHEIMERS DISEASE

Caspase-cleaved tau exhibits rapid memory impairment associated with tau oligomers in a transgenic mouse model

(2016) YoungDoo Kim et al.   NEUROBIOLOGY OF DISEASE

Gamma Secretase-Activating Protein Is a Substrate for Caspase-3: Implications for Alzheimer’s Disease

(2015) Jin Chu et al.   BIOLOGICAL PSYCHIATRY

Stimulation of EphB2 attenuates tau phosphorylation through PI3K/Akt-mediated inactivation of glycogen synthase kinase-3β

(2015) Jun Jiang et al.   Scientific Reports

BRI2 ectodomain affects Aβ42 fibrillation and tau truncation in human neuroblastoma cells

(2014) M. Del Campo et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Caspases: Therapeutic Targets in Neurologic Disease

(2014) Carol M. Troy et al.   Neurotherapeutics

The 12-15-lipoxygenase is a modulator of Alzheimer's-related tau pathologyin vivo

(2013) Phillip F. Giannopoulos et al.   AGING CELL

Gene knockout of 5-lipoxygenase rescues synaptic dysfunction and improves memory in the triple-transgenic model of Alzheimer's disease

(2013) P F Giannopoulos et al.   MOLECULAR PSYCHIATRY

5-Lipoxygenase gene transfer worsens memory, amyloid, and tau brain pathologies in a mouse model of alzheimer disease

(2012) Jin Chu et al.   ANNALS OF NEUROLOGY

Inhibition of Gsk3β activity improves β-cell function in c-KitWv/+ male mice

(2012) Zhi-Chao Feng et al.   LABORATORY INVESTIGATION

Retinoic acid protects against proteasome inhibition associated cell death in SH-SY5Y cells via the AKT pathway

(2012) Benxu Cheng et al.   NEUROCHEMISTRY INTERNATIONAL

Lifelong Management of Amyloid-Beta Metabolism to Prevent Alzheimer's Disease

(2012) Sam Gandy   NEW ENGLAND JOURNAL OF MEDICINE

Caspase-3 in the central nervous system: beyond apoptosis

(2012) Marcello D’Amelio et al.   TRENDS IN NEUROSCIENCES

Amyloid β-Mediated Cell Death of Cultured Hippocampal Neurons Reveals Extensive Tau Fragmentation without Increased Full-length Tau Phosphorylation

(2011) Jack Reifert et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

5-lipoxygenase as an endogenous modulator of amyloid beta formation in vivo

(2010) Jin Chu et al.   ANNALS OF NEUROLOGY

Angiotensin II Type 1 Receptor–Activated Caspase-3 Through Ras/Mitogen-Activated Protein Kinase/Extracellular Signal-Regulated Kinase in the Rostral Ventrolateral Medulla Is Involved in Sympathoexcitation in Stroke-Prone Spontaneously Hypertensive Rats

(2010) Takuya Kishi et al.   HYPERTENSION

Caspase-3 triggers early synaptic dysfunction in a mouse model of Alzheimer's disease

(2010) Marcello D'Amelio et al.   NATURE NEUROSCIENCE

Is overexpression of HER-2 a predictor of prognosis in colorectal cancer?

(2009) Dara O Kavanagh et al.   BMC CANCER

A non-apoptotic function of caspase-3 in pharmacologically-induced differentiation of K562 cells

(2009) M Sztiller-Sikorska et al.   BRITISH JOURNAL OF PHARMACOLOGY

SitePredicting the cleavage of proteinase substrates

(2009) Jelle Verspurten et al.   TRENDS IN BIOCHEMICAL SCIENCES

Erythroid expansion and survival in response to acute anemia stress: The role of EPO receptor, GATA-1, Bcl-xL and caspase-3

(2008) G AISPURU et al.   CELL BIOLOGY INTERNATIONAL

Inhibition of Wnt and PI3K Signaling Modulates GSK-3β Activity and Induces Morphological Changes in Cortical Neurons: Role of Tau Phosphorylation

(2008) Octavio Mercado-Gómez et al.   NEUROCHEMICAL RESEARCH