Neuroprotective effects of berberine in animal models of Alzheimer’s disease: a systematic review of pre-clinical studies

Berberine Attenuates Calyculin A-Induced Cytotoxicity and Tau Hyperphosphorylation in HEK293 Cells

(2018) Guang Yu et al.   JOURNAL OF ALZHEIMERS DISEASE

Berberine improves cognitive impairment by promoting autophagic clearance and inhibiting production of β-amyloid in APP/tau/PS1 mouse model of Alzheimer's disease

(2017) Min Huang et al.   EXPERIMENTAL GERONTOLOGY

Berberine attenuates cognitive impairment and ameliorates tau hyperphosphorylation by limiting the self-perpetuating pathogenic cycle between NF-κB signaling, oxidative stress and neuroinflammation

(2017) Wenbo He et al.   Pharmacological Reports

Berberine Ameliorates Diabetes-Associated Cognitive Decline through Modulation of Aberrant Inflammation Response and Insulin Signaling Pathway in DM Rats

(2017) Qingjie Chen et al.   Frontiers in Pharmacology

Editorial (Thematic Issue: From Current Diagnostic Tools and Therapeutics for Alzheimer's Disease Towards Earlier Diagnostic Markers and Treatment Targets)

(2016) Slavica Krantic   Current Alzheimer Research

Berberine protects against memory impairment and anxiogenic-like behavior in rats submitted to sporadic Alzheimer’s-like dementia: Involvement of acetylcholinesterase and cell death

(2016) Juliana Sorraila de Oliveira et al.   NEUROTOXICOLOGY

The therapeutic potential of berberine against the altered intrinsic properties of the CA1 neurons induced by Aβ neurotoxicity

(2015) Masoud Haghani et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Protective effect of berberine, an isoquinoline alkaloid ameliorates ethanol-induced oxidative stress and memory dysfunction in rats

(2015) Shaktipal Patil et al.   PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR

Berberine rescues d-galactose-induced synaptic/memory impairment by regulating the levels of Arc

(2013) Pei-Yan Zhan et al.   PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR

Hippocampal synaptic plasticity restoration and anti-apoptotic effect underlie berberine improvement of learning and memory in streptozotocin-diabetic rats

(2012) Hamid Kalalian-Moghaddam et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Phellodendron amurenseand Its Major Alkaloid Compound, Berberine Ameliorates Scopolamine-Induced Neuronal Impairment and Memory Dysfunction in Rats

(2012) Bombi Lee et al.   KOREAN JOURNAL OF PHYSIOLOGY & PHARMACOLOGY

Berberine ameliorates β-amyloid pathology, gliosis, and cognitive impairment in an Alzheimer's disease transgenic mouse model

(2012) Siva Sundara Kumar Durairajan et al.   NEUROBIOLOGY OF AGING

Molecular Basis of Inhibitory Activities of Berberine against Pathogenic Enzymes in Alzheimer's Disease

(2012) Hong-Fang Ji et al.   TheScientificWorldJOURNAL

Protection of cholinergic and antioxidant system contributes to the effect of berberine ameliorating memory dysfunction in rat model of streptozotocin-induced diabetes

(2011) Pravinkumar Bhutada et al.   BEHAVIOURAL BRAIN RESEARCH

Neuroprotective effects of berberine in neurodegeneration model rats induced by ibotenic acid

(2010) Jung Su Lim et al.   Animal Cells and Systems

CONSORT 2010 Statement: updated guidelines for reporting parallel group randomised trials

(2010) Kenneth F Schulz et al.   BMC Medicine

Berberine inhibits NADPH oxidase mediated superoxide anion production in macrophagesThis article is one of a selection of papers published in a Special Issue on Oxidative Stress in Health and Disease.

(2010) Lindsei K. Sarna et al.   CANADIAN JOURNAL OF PHYSIOLOGY AND PHARMACOLOGY

Anti-Alzheimer and Antioxidant Activities of Coptidis Rhizoma Alkaloids

(2009) Hyun Ah Jung et al.   BIOLOGICAL & PHARMACEUTICAL BULLETIN

Oxidative Stress Signaling in Alzheimers Disease

(2008) B. Su et al.   Current Alzheimer Research

Pharmacological and therapeutic effects of Berberis vulgaris and its active constituent, berberine

(2008) Mohsen Imanshahidi et al.   PHYTOTHERAPY RESEARCH