Neuroprotective Effects of Dexmedetomidine Preconditioning on Oxygen-glucose Deprivation-reoxygenation Injury in PC12 Cells via Regulation of Ca2+-STIM1/Orai1 Signaling

Crosstalk Between Autophagy and Cerebral Ischemia

(2019) Yulin Sun et al.   Frontiers in Neuroscience

A systematic review of interventions to facilitate extubation in patients difficult-to-wean due to delirium, agitation, or anxiety and a meta-analysis of the effect of dexmedetomidine

(2019) Sébastien Dupuis et al.   Canadian Journal of Anesthesia-Journal canadien d anesthesie

Suppression of long non-coding RNA RMRP ameliorates oxygen-glucose deprivation/re-oxygenation-induced neural cells injury by inhibiting autophagy and PI3K/Akt/mTOR-mediated apoptosis

(2019) Zheyi Zhou et al.   BIOSCIENCE REPORTS

Urolithin A‐activated autophagy but not mitophagy protects against ischemic neuronal injury by inhibiting ER stress in vitro and in vivo

(2019) Anil Ahsan et al.   CNS Neuroscience & Therapeutics

Identification of Candidate Genes and Pathways in Dexmedetomidine-Induced Cardioprotection in the Rat Heart by Bioinformatics Analysis

(2019) Yusuke Yoshikawa et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Role of JNK Signaling Pathway in Dexmedetomidine Post-Conditioning-Induced Reduction of the Inflammatory Response and Autophagy Effect of Focal Cerebral Ischemia Reperfusion Injury in Rats

(2019) Yulin Zhu et al.   INFLAMMATION

Novel cannabis flavonoid, cannflavin A displays both a hormetic and neuroprotective profile against amyloid β-mediated neurotoxicity in PC12 cells: Comparison with geranylated flavonoids, mimulone and diplacone

(2019) Carly Eggers et al.   BIOCHEMICAL PHARMACOLOGY

Neuroprotective effect of bispectral index-guided fast-track anesthesia using sevoflurane combined with dexmedetomidine for intracranial aneurysm embolization

(2018) Zhong-yuan Xia et al.   Neural Regeneration Research

Activation of Ca2+-sensing receptor as a protective pathway to reduce Cadmium-induced cytotoxicity in renal proximal tubular cells

(2018) Jie Gu et al.   Scientific Reports

Effects of Dexmedetomidine-Isoflurane versus Isoflurane Anesthesia on Brain Injury After Cardiac Valve Replacement Surgery

(2017) Fang Kang et al.   JOURNAL OF CARDIOTHORACIC AND VASCULAR ANESTHESIA

Protection of Dexmedetomidine Against Ischemia/Reperfusion-Induced Apoptotic Insults to Neuronal Cells Occurs Via an Intrinsic Mitochondria-Dependent Pathway

(2017) Gong-Jhe Wu et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

The protective effects of dexmedetomidine on ischemic brain injury: A meta-analysis

(2017) Lianxiang Jiang et al.   JOURNAL OF CLINICAL ANESTHESIA

Dexmedetomidine in perioperative acute pain management: a non-opioid adjuvant analgesic

(2017) Chaoliang Tang et al.   Journal of Pain Research

Stromal Interaction Molecule 1 rescues store-operated calcium entry and protects NG115-401L cells against cell death induced by endoplasmic reticulum and mitochondrial oxidative stress

(2016) Changfeng Zhang et al.   NEUROCHEMISTRY INTERNATIONAL

Voltage-gated calcium channel blockers deregulate macroautophagy in cardiomyocytes

(2015) Charumathi Pushparaj et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Blockade of SOCE protects HT22 cells from hydrogen peroxide-induced apoptosis

(2013) Wei Rao et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Role of the inositol 1,4,5-trisphosphate receptor/Ca2+-release channel in autophagy

(2012) Jan B Parys et al.   Cell Communication and Signaling

Suppression of Dendritic Cell-mediated Responses by Genes in Calcium and Cysteine Protease Pathways duringMycobacterium tuberculosisInfection

(2012) Jhalak Singhal et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Ca2+, autophagy and protein degradation: Thrown off balance in neurodegenerative disease

(2010) Jose Miguel Vicencio et al.   CELL CALCIUM

Progress in the unraveling of the endoplasmic reticulum stress/autophagy pathway and cancer: Implications for future therapeutic approaches

(2010) Stephen M. Schleicher et al.   DRUG RESISTANCE UPDATES

Cell Death Mechanisms and Their Implications in Toxicology

(2010) Sten Orrenius et al.   TOXICOLOGICAL SCIENCES

An increase in intracellular Ca2+ is required for the activation of mitochondrial calpain to release AIF during cell death

(2008) E Norberg et al.   CELL DEATH AND DIFFERENTIATION

Cadmium-induced autophagy and apoptosis are mediated by a calcium signaling pathway

(2008) S. H. Wang et al.   CELLULAR AND MOLECULAR LIFE SCIENCES