Single-cell transcriptomic analysis reveals differential cell subpopulations and distinct phenotype transition in normal and dissected ascending aorta

Single-Cell RNA Sequencing Technology Revealed the Pivotal Role of Fibroblast Heterogeneity in Angiotensin II-Induced Abdominal Aortic Aneurysms

(2022) Yingzheng Weng et al.   DNA AND CELL BIOLOGY

Treatment strategies and in-hospital mortality in patients with type A acute aortic dissection and coronary artery involvement

(2022) Osamu Hashimoto et al.   JOURNAL OF THORACIC AND CARDIOVASCULAR SURGERY

Single-cell immunoprofiling after immunotherapy for allergic rhinitis reveals functional suppression of pathogenic TH2 cells and clonal conversion

(2022) Tomohisa Iinuma et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Zedoarondiol inhibits atherosclerosis by regulating monocyte migration and adhesion via CXCL12/CXCR4 pathway

(2022) Hua Chai et al.   PHARMACOLOGICAL RESEARCH

Murine double minute 2 aggravates adipose tissue dysfunction through ubiquitin-mediated six-transmembrane epithelial antigen of prostate 4 degradation

(2022) Wei Zhao et al.   iScience

Eif2b3 mutants recapitulate phenotypes of Vanishing White Matter Disease and validate novel disease alleles in zebrafish

(2021) Yu-Ri Lee et al.   HUMAN MOLECULAR GENETICS

Single‐cell RNA sequencing in cancer research

(2021) Yijie Zhang et al.   JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

Epidemiology of aortic dissection

(2021) Indrani Sen et al.   Seminars in Vascular Surgery

A novel prognostic biomarker LCP2 correlates with metastatic melanoma-infiltrating CD8+ T cells

(2021) Zijun Wang et al.   Scientific Reports

The Prognostic Potential of Human Prostate Cancer-Associated Macrophage Subtypes as Revealed by Single-cell Transcriptomics

(2021) Joseph C Siefert et al.   MOLECULAR CANCER RESEARCH

Curcumin Alleviates Aβ42-Induced Neuronal Metabolic Dysfunction via the Thrb/SIRT3 Axis and Improves Cognition in APPTG Mice

(2021) Min Liu et al.   NEUROCHEMICAL RESEARCH

Tnfaip6 Secreted by Bone Marrow–Derived Mesenchymal Stem Cells Attenuates TNBS-Induced Colitis by Modulating Follicular Helper T Cells and Follicular Regulatory T Cells Balance in Mice

(2021) Guangli Gu et al.   Frontiers in Pharmacology

Results of ascending aortic and arch replacement for type A aortic dissection

(2020) Keiji Uchida et al.   JOURNAL OF THORACIC AND CARDIOVASCULAR SURGERY

Neutrophils as regulators of cardiovascular inflammation

(2020) Carlos Silvestre-Roig et al.   Nature Reviews Cardiology

Immunological roles of intestinal mesenchymal cells

(2020) Carolyn A. Thomson et al.   IMMUNOLOGY

ENO1‐targeted superparamagnetic iron oxide nanoparticles for detecting pancreatic cancer by magnetic resonance imaging

(2020) Lei Wang et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Single-cell transcriptome profiling reveals neutrophil heterogeneity in homeostasis and infection

(2020) Xuemei Xie et al.   NATURE IMMUNOLOGY

Reversal of pre-existing NGFR-driven tumor and immune therapy resistance

(2020) Julia Boshuizen et al.   Nature Communications

Angiotensin-converting enzyme 2 augments the effects of endothelial progenitor cells–exosomes on vascular smooth muscle cell phenotype transition

(2020) Jinju Wang et al.   CELL AND TISSUE RESEARCH

Single-Cell Transcriptome Analysis Reveals Dynamic Cell Populations and Differential Gene Expression Patterns in Control and Aneurysmal Human Aortic Tissue

(2020) Yanming Li et al.   CIRCULATION

Dynamics of Cardiac Neutrophil Diversity in Murine Myocardial Infarction

(2020) Ehsan Vafadarnejad et al.   CIRCULATION RESEARCH

The regulation of IGFBP3 by BMP2 has a role in human endometrial remodeling

(2020) Jin Luo et al.   FASEB JOURNAL

Polycystin-1 Downregulation Induced Vascular Smooth Muscle Cells Phenotypic Alteration and Extracellular Matrix Remodeling in Thoracic Aortic Dissection

(2020) Jing Zhang et al.   Frontiers in Physiology

The Relevance of Vascular Endothelial Growth Factor, Hypoxia Inducible Factor-1 Alpha, and Clusterin in Carotid Plaque Instability

(2019) Jelena Basic et al.   Journal of Stroke & Cerebrovascular Diseases

Forced expression of NR4A3 induced the differentiation of human neuroblastoma-derived NB1 cells

(2019) Takayuki Hirano et al.   MEDICAL ONCOLOGY

EglN3 hydroxylase stabilizes BIM-EL linking VHL type 2C mutations to pheochromocytoma pathogenesis and chemotherapy resistance

(2019) Shuijie Li et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Layer-specific hyperelastic and viscoelastic characterization of human descending thoracic aortas

(2019) Marco Amabili et al.   Journal of the Mechanical Behavior of Biomedical Materials

Host resistance factor SLC11A1 restricts Salmonella growth through magnesium deprivation

(2019) Olivier Cunrath et al.   SCIENCE

Notch3 signalling and vascular remodelling in pulmonary arterial hypertension

(2019) Hannah E. Morris et al.   CLINICAL SCIENCE

Mechanism of SEMA3G knockdown-mediated attenuation of high-fat diet-induced obesity

(2019) Min Liu et al.   JOURNAL OF ENDOCRINOLOGY

Hypoxia regulates the mitochondrial activity of hepatocellular carcinoma cells through HIF/HEY1/PINK1 pathway

(2019) David Kung-Chun Chiu et al.   Cell Death & Disease

Defective NOTCH signalling drives smooth muscle cell death and differentiation in bicuspid aortic valve aortopathy†

(2018) Oliver J Harrison et al.   EUROPEAN JOURNAL OF CARDIO-THORACIC SURGERY

IGFBP4 Is Required for Adipogenesis and Influences the Distribution of Adipose Depots

(2017) David E Maridas et al.   ENDOCRINOLOGY

STEAP4: its emerging role in metabolism and homeostasis of cellular iron and copper

(2017) Rachel T Scarl et al.   JOURNAL OF ENDOCRINOLOGY

Single-cell sequencing reveals dissociation-induced gene expression in tissue subpopulations

(2017) Susanne C van den Brink et al.   NATURE METHODS

Altered Smooth Muscle Cell Force Generation as a Driver of Thoracic Aortic Aneurysms and DissectionsHighlights

(2016) Dianna M. Milewicz et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Aortic dissection

(2016) Christoph A. Nienaber et al.   Nature Reviews Disease Primers

Adventitial CXCL1/G-CSF Expression in Response to Acute Aortic Dissection Triggers Local Neutrophil Recruitment and Activation Leading to Aortic Rupture

(2015) A. Anzai et al.   CIRCULATION RESEARCH

RGS5 promotes arterial growth during arteriogenesis

(2014) C. Arnold et al.   EMBO Molecular Medicine

Hyperhomocysteinemia Exaggerates Adventitial Inflammation and Angiotensin II−Induced Abdominal Aortic Aneurysm in Mice

(2012) Ziyi Liu et al.   CIRCULATION RESEARCH

Structures of the CXCR4 Chemokine GPCR with Small-Molecule and Cyclic Peptide Antagonists

(2010) B. Wu et al.   SCIENCE

An adventitial IL-6/MCP1 amplification loop accelerates macrophage-mediated vascular inflammation leading to aortic dissection in mice

(2009) Brian C. Tieu et al.   JOURNAL OF CLINICAL INVESTIGATION