Hydrophobicity Determines the Bacterial Killing Rate of α-Helical Antimicrobial Peptides and Influences the Bacterial Resistance Development

Antibacterial peptide NZ2114-loaded hydrogel accelerates Staphylococcus aureus-infected wound healing

(2022) Yan Huang et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

Novel β-Hairpin Antimicrobial Peptides Containing the β-Turn Sequence of -RRRF- Having High Cell Selectivity and Low Incidence of Drug Resistance

(2022) Beibei Li et al.   JOURNAL OF MEDICINAL CHEMISTRY

A molecular architectural design that promises potent antimicrobial activity against multidrug-resistant pathogens

(2021) Bing Yuan et al.   NPG Asia Materials

Lipid Phase Influences the Dynamic Interactions between Graphene Oxide Nanosheets and a Phospholipid Membrane

(2021) Zhonglan Chen et al.   JOURNAL OF PHYSICAL CHEMISTRY B

PEGylation of the Antimicrobial Peptide PG-1: A Link between Propensity for Nanostructuring and Capacity of the Antitrypsin Hydrolytic Ability

(2021) Weikang Yu et al.   JOURNAL OF MEDICINAL CHEMISTRY

Antimicrobial host defence peptides: functions and clinical potential

(2020) Neeloffer Mookherjee et al.   NATURE REVIEWS DRUG DISCOVERY

Outermembrane lipid secretion and the innate immune response to Gram-negative bacteria.

(2020) Nicole P. Giordano et al.   INFECTION AND IMMUNITY

Correlation between Single Molecular Dynamics and Biological Functions of Antimicrobial Peptide Melittin

(2020) Cheng Xu et al.   Journal of Physical Chemistry Letters

Antimicrobial peptides: Application informed by evolution

(2020) Brian P. Lazzaro et al.   SCIENCE

The value of antimicrobial peptides in the age of resistance

(2020) Maria Magana et al.   LANCET INFECTIOUS DISEASES

Design of sea snake antimicrobial peptide derivative with therapeutic potential against drug-resistant bacterial infection

(2020) jiuxiang gao et al.   ACS Infectious Diseases

Comprehensive genome based analysis of Vibrio parahaemolyticus for identifying novel drug and vaccine molecules: Subtractive proteomics and vaccinomics approach

(2020) Mahmudul Hasan et al.   PLoS One

HEXIM1 Peptide Exhibits Antimicrobial Activity Against Antibiotic Resistant Bacteria Through Guidance of Cell Penetrating Peptide

(2019) Pooi Leng Ho et al.   Frontiers in Microbiology

Antimicrobial Peptides with High Proteolytic Resistance for Combating Gram-Negative Bacteria

(2019) Jiajun Wang et al.   JOURNAL OF MEDICINAL CHEMISTRY

Antibacterial action of synthetic antilipopolysaccharide peptides (SALP) involves neutralization of both membrane‐bound and free toxins

(2019) Wilmar Correa et al.   FEBS Journal

Comparative mode of action of the antimicrobial peptide melimine and its derivative Mel4 against Pseudomonas aeruginosa

(2019) Muhammad Yasir et al.   Scientific Reports

Envelope stress responses: balancing damage repair and toxicity

(2019) Angela M. Mitchell et al.   NATURE REVIEWS MICROBIOLOGY

Improving the estimation of the global burden of antimicrobial resistant infections

(2019) Direk Limmathurotsakul et al.   LANCET INFECTIOUS DISEASES

Structural analysis and mode of action of BMAP-27, a cathelicidin-derived antimicrobial peptide

(2019) Sungtae Yang et al.   PEPTIDES

The antimicrobial peptide ZY4 combats multidrug-resistantPseudomonas aeruginosaandAcinetobacter baumanniiinfection

(2019) James Mwangi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Combating Drug-Resistant Fungi with Novel Imperfectly Amphipathic Palindromic Peptides

(2018) Jiajun Wang et al.   JOURNAL OF MEDICINAL CHEMISTRY

Structural basis for endotoxin neutralisation and anti-inflammatory activity of thrombin-derived C-terminal peptides

(2018) Rathi Saravanan et al.   Nature Communications

Designing Antibacterial Peptides with Enhanced Killing Kinetics

(2018) Faiza H. Waghu et al.   Frontiers in Microbiology

The activity of a mammalian proline-rich peptide against Gram-negative bacteria, including drug-resistant strains, relies on a nonmembranolytic mode of action

(2018) Tecla Ciociola et al.   Infection and Drug Resistance

Functional Characterization of a Novel Lipopolysaccharide-Binding Antimicrobial and Anti-Inflammatory Peptide in Vitro and in Vivo

(2018) Baishuang Zeng et al.   JOURNAL OF MEDICINAL CHEMISTRY

Antimicrobial peptides: Promising alternatives in the post feeding antibiotic era

(2018) Jiajun Wang et al.   MEDICINAL RESEARCH REVIEWS

As-CATH4 and 5, two vertebrate-derived natural host defense peptides, enhance the immuno-resistance efficiency against bacterial infections in Chinese mitten crab, Eriocheir sinensis

(2017) Zhilai Guo et al.   FISH & SHELLFISH IMMUNOLOGY

New Mouse Model for Chronic Infections by Gram-Negative Bacteria Enabling the Study of Anti-Infective Efficacy and Host-Microbe Interactions

(2017) Daniel Pletzer et al.   mBio

Membrane-active Antimicrobial Peptides as Template Structures for Novel Antibiotic Agents

(2016) Karl Lohner   CURRENT TOPICS IN MEDICINAL CHEMISTRY

Antimicrobial Peptides Under Clinical Trials

(2016) Katarzyna E. Greber et al.   CURRENT TOPICS IN MEDICINAL CHEMISTRY

Single-molecule visualization of dynamic transitions of pore-forming peptides among multiple transmembrane positions

(2016) Ying Li et al.   Nature Communications

Imaging the antimicrobial mechanism(s) of cathelicidin-2

(2016) Viktoria A. F. Schneider et al.   Scientific Reports

NMR Structures and Interactions of Antimicrobial Peptides with Lipopolysaccharide: Connecting Structures to Functions

(2015) Surajit Bhattacharjya   CURRENT TOPICS IN MEDICINAL CHEMISTRY

Identification and Characterization of the First Cathelicidin from Sea Snakes with Potent Antimicrobial and Anti-inflammatory Activity and Special Mechanism

(2015) Lin Wei et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

APD3: the antimicrobial peptide database as a tool for research and education

(2015) Guangshun Wang et al.   NUCLEIC ACIDS RESEARCH

Poly-lysine peptidomimetics having potent antimicrobial activity without hemolytic activity

(2014) Mija Ahn et al.   AMINO ACIDS

Clavanin A Improves Outcome of Complications from Different Bacterial Infections

(2014) Osmar N. Silva et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Antimicrobial properties and interaction of two Trp-substituted cationic antimicrobial peptides with a lipid bilayer

(2014) Xiaonan Bi et al.   JOURNAL OF ANTIBIOTICS

GROMACS 4.5: a high-throughput and highly parallel open source molecular simulation toolkit

(2013) Sander Pronk et al.   BIOINFORMATICS

Naturally Occurring Antimicrobial Peptide OH-CATH30 Selectively Regulates the Innate Immune Response To Protect against Sepsis

(2013) Sheng-An Li et al.   JOURNAL OF MEDICINAL CHEMISTRY

Characterization of Antimicrobial, Cytotoxic, and Antiendotoxin Properties of Short Peptides with Different Hydrophobic Amino Acids at “a” and “d” Positions of a Heptad Repeat Sequence

(2013) Sarfuddin Azmi et al.   JOURNAL OF MEDICINAL CHEMISTRY

Roles of Hydrophobicity and Charge Distribution of Cationic Antimicrobial Peptides in Peptide-Membrane Interactions

(2012) Lois M. Yin et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Biophysical Mechanisms of Endotoxin Neutralization by Cationic Amphiphilic Peptides

(2011) Yani Kaconis et al.   BIOPHYSICAL JOURNAL

The antimicrobial effect of Iseganan HCl oral solution in patients receiving stomatotoxic chemotherapy: analysis from a multicenter, double-blind, placebo-controlled, randomized, phase III clinical trial

(2011) Sharon Elad et al.   JOURNAL OF ORAL PATHOLOGY & MEDICINE

Real-time attack on single Escherichia coli cells by the human antimicrobial peptide LL-37

(2011) K. A. Sochacki et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Effect of the Hydrophobicity to Net Positive Charge Ratio on Antibacterial and Anti-Endotoxin Activities of Structurally Similar Antimicrobial Peptides

(2010) Yosef Rosenfeld et al.   BIOCHEMISTRY

Morphological Changes Induced by the Action of Antimicrobial Peptides on Supported Lipid Bilayers

(2010) Ahmad Arouri et al.   JOURNAL OF PHYSICAL CHEMISTRY B

Structure-Activity Relationships of Multifunctional Host Defence Peptides

(2010) J. Kindrachuk et al.   MINI-REVIEWS IN MEDICINAL CHEMISTRY

Antibacterial Effects of Poly(2-(dimethylamino ethyl)methacrylate) against Selected Gram-Positive and Gram-Negative Bacteria

(2009) Lee-Anne B. Rawlinson et al.   BIOMACROMOLECULES

GROMACS 4:  Algorithms for Highly Efficient, Load-Balanced, and Scalable Molecular Simulation

(2008) Berk Hess et al.   Journal of Chemical Theory and Computation