Involvement of circRNAs in the Development of Heart Failure

Noncoding RNAs in Cardiac Hypertrophy and Heart Failure

(2022) Peilei Lu et al.   Cells

Roles of exosomal circRNAs in tumour immunity and cancer progression

(2022) Baojing Tuo et al.   Cell Death & Disease

CircRNAs in Diabetic Cardiomyopathy

(2021) Hengquan Wan et al.   CLINICA CHIMICA ACTA

Non-coding RNAs in Cardiac Regeneration

(2021) Ting Yuan et al.   Frontiers in Physiology

Decoding the complexity of circular RNAs in cardiovascular disease

(2021) Amit Kumar Rai et al.   PHARMACOLOGICAL RESEARCH

Circle the Cardiac Remodeling With circRNAs

(2021) Tiqun Yang et al.   Frontiers in Cardiovascular Medicine

Circ_LAS1L regulates cardiac fibroblast activation, growth, and migration through miR‐125b/SFRP5 pathway

(2020) Li‐ye Sun et al.   CELL BIOCHEMISTRY AND FUNCTION

CircFOXK2 Promotes Growth and Metastasis of Pancreatic Ductal Adenocarcinoma by Complexing with RNA Binding Proteins and Sponging MiR-942

(2020) Chi Hin Wong et al.   CANCER RESEARCH

Engineered Circular RNA Sponges Act as miRNA Inhibitors to Attenuate Pressure Overload-Induced Cardiac Hypertrophy

(2020) Annadoray Lavenniah et al.   MOLECULAR THERAPY

The expanding regulatory mechanisms and cellular functions of circular RNAs

(2020) Ling-Ling Chen   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Prediction of the differentially expressed circRNAs to decipher their roles in the onset of human colorectal cancers

(2020) Rajabrata Bhuyan et al.   GENE

CircBPTF knockdown ameliorates high glucose-induced inflammatory injuries and oxidative stress by targeting the miR-384/LIN28B axis in human umbilical vein endothelial cells

(2020) Wei Zhang et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

Insights into the role of circular RNA in macrophage activation and fibrosis disease

(2020) Mengxue Xu et al.   PHARMACOLOGICAL RESEARCH

Protein-Related Circular RNAs in Human Pathologies

(2020) Olga Wawrzyniak et al.   Cells

Non-coding RNAs: The key detectors and regulators in cardiovascular disease

(2020) Linwen Zhu et al.   GENOMICS

circPAN3 exerts a profibrotic role via sponging miR-221 through FoxO3/ATG7-activated autophagy in a rat model of myocardial infarction

(2020) Fei Li et al.   LIFE SCIENCES

circRNA Hipk3 Induces Cardiac Regeneration after Myocardial Infarction in Mice by Binding to Notch1 and miR-133a

(2020) Xiaoyun Si et al.   Molecular Therapy-Nucleic Acids

Circular RNAs: Functions and Clinical Significance in Cardiovascular Disease

(2020) Lei Zhang et al.   Frontiers in Cell and Developmental Biology

Circ_Lrp6, a Circular RNA Enriched in Vascular Smooth Muscle Cells, Acts as a Sponge Regulating miRNA-145 Function

(2019) Ignacio Fernando Hall et al.   CIRCULATION RESEARCH

Targeting the highly abundant circular RNA circSlc8a1 in cardiomyocytes attenuates pressure overload induced hypertrophy

(2019) Tingsen Benson Lim et al.   CARDIOVASCULAR RESEARCH

Inhibition of circHIPK3 prevents angiotensin II-induced cardiac fibrosis by sponging miR-29b-3p

(2019) Huaner Ni et al.   INTERNATIONAL JOURNAL OF CARDIOLOGY

Loss of Super-Enhancer-Regulated circRNA Nfix Induces Cardiac Regeneration After Myocardial Infarction in Adult Mice

(2019) Senlin Huang et al.   CIRCULATION

Circular RNA circSLC8A1 acts as a sponge of miR-130b/miR-494 in suppressing bladder cancer progression via regulating PTEN

(2019) Qun Lu et al.   Molecular Cancer

A Novel Circular RNA Mediates Pyroptosis of Diabetic Cardiomyopathy by Functioning as a Competing Endogenous RNA

(2019) Fan Yang et al.   Molecular Therapy-Nucleic Acids

Upregulation of Circular RNA CircNFIB Attenuates Cardiac Fibrosis by Sponging miR-433

(2019) Yujiao Zhu et al.   Frontiers in Genetics

Circular RNA circRNA_000203 aggravates cardiac hypertrophy via suppressing miR-26b-5p and miR-140-3p binding to Gata4

(2019) Hui Li et al.   CARDIOVASCULAR RESEARCH

Profiling and functional analysis of differentially expressed circular RNAs in high glucose‐induced human umbilical vein endothelial cells

(2019) Guoxi Jin et al.   FEBS Open Bio

Identifying Cancer-Specific circRNA–RBP Binding Sites Based on Deep Learning

(2019) Zhengfeng Wang et al.   MOLECULES

Predicting RNA–protein binding sites and motifs through combining local and global deep convolutional neural networks

(2018) Xiaoyong Pan et al.   BIOINFORMATICS

Prediction of RNA-protein sequence and structure binding preferences using deep convolutional and recurrent neural networks

(2018) Xiaoyong Pan et al.   BMC GENOMICS

Diabetic Cardiomyopathy

(2018) Guanghong Jia et al.   CIRCULATION RESEARCH

Anti-apoptosis in nonmyocytes and pro-autophagy in cardiomyocytes: two strategies against postinfarction heart failure through regulation of cell death/degeneration

(2018) Genzou Takemura et al.   HEART FAILURE REVIEWS

Mechanisms of physiological and pathological cardiac hypertrophy

(2018) Michinari Nakamura et al.   Nature Reviews Cardiology

A novel protein encoded by the circular form of the SHPRH gene suppresses glioma tumorigenesis

(2018) Maolei Zhang et al.   ONCOGENE

MicroRNA-384-3p inhibits retinal neovascularization through targeting hexokinase 2 in mice with diabetic retinopathy

(2018) Fei Xia et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Using plasma circRNA_002453 as a novel biomarker in the diagnosis of lupus nephritis

(2018) Qingqing Ouyang et al.   MOLECULAR IMMUNOLOGY

The circular RNA ACR attenuates myocardial ischemia/reperfusion injury by suppressing autophagy via modulation of the Pink1/ FAM65B pathway

(2018) Lu-Yu Zhou et al.   CELL DEATH AND DIFFERENTIATION

The interaction of circRNAs and RNA binding proteins: An important part of circRNA maintenance and function

(2018) Jiankun Zang et al.   JOURNAL OF NEUROSCIENCE RESEARCH

Circular RNAs in heart failure

(2017) Yvan Devaux et al.   EUROPEAN JOURNAL OF HEART FAILURE

The Circular RNA Interacts with STAT3, Increasing Its Nuclear Translocation and Wound Repair by Modulating Dnmt3a and miR-17 Function

(2017) Zhen-Guo Yang et al.   MOLECULAR THERAPY

Identification of HuR target circular RNAs uncovers suppression of PABPN1 translation by CircPABPN1

(2017) Kotb Abdelmohsen et al.   RNA Biology

CircRNA_000203 enhances the expression of fibrosis-associated genes by derepressing targets of miR-26b-5p, Col1a2 and CTGF, in cardiac fibroblasts

(2017) Chun-Mei Tang et al.   Scientific Reports

A Circular RNA Binds To and Activates AKT Phosphorylation and Nuclear Localization Reducing Apoptosis and Enhancing Cardiac Repair

(2017) Yan Zeng et al.   Theranostics

The Function and Therapeutic Potential of Long Non-coding RNAs in Cardiovascular Development and Disease

(2017) Clarissa P.C. Gomes et al.   Molecular Therapy-Nucleic Acids

Long Noncoding RNAs and Cardiac Disease

(2017) Simona Greco et al.   ANTIOXIDANTS & REDOX SIGNALING

Circular RNAs: analysis, expression and potential functions

(2016) Steven P. Barrett et al.   DEVELOPMENT

A circular RNA protects the heart from pathological hypertrophy and heart failure by targeting miR-223

(2016) Kun Wang et al.   EUROPEAN HEART JOURNAL

Cardiovascular disease in Europe: epidemiological update 2016

(2016) Nick Townsend et al.   EUROPEAN HEART JOURNAL

Monocyte and macrophage contributions to cardiac remodeling

(2016) Maarten Hulsmans et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Characterization of circular RNAs in human, mouse and rat hearts

(2016) Stanislas Werfel et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Myocardial Infarction-Associated Circular RNA Predicting Left Ventricular Dysfunction

(2016) Melanie Vausort et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Activating autophagy to potentiate immunogenic chemotherapy and radiation therapy

(2016) Lorenzo Galluzzi et al.   Nature Reviews Clinical Oncology

Non-coding RNAs in Development and Disease: Background, Mechanisms, and Therapeutic Approaches

(2016) Julia Beermann et al.   PHYSIOLOGICAL REVIEWS

Circular non-coding RNA ANRIL modulates ribosomal RNA maturation and atherosclerosis in humans

(2016) Lesca M. Holdt et al.   Nature Communications

The Circular RNA Cdr1as Promotes Myocardial Infarction by Mediating the Regulation of miR-7a on Its Target Genes Expression

(2016) Hai-Hua Geng et al.   PLoS One

circRNADb: A comprehensive database for human circular RNAs with protein-coding annotations

(2016) Xiaoping Chen et al.   Scientific Reports

Mechanoregulation of cardiac myofibroblast differentiation: implications for cardiac fibrosis and therapy

(2015) Kar Wey Yong et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Pathophysiology of cardiac hypertrophy and heart failure: signaling pathways and novel therapeutic targets

(2015) Yow Keat Tham et al.   ARCHIVES OF TOXICOLOGY

The RNA Binding Protein Quaking Regulates Formation of circRNAs

(2015) Simon J. Conn et al.   CELL

Diabetic Cardiovascular Disease Induced by Oxidative Stress

(2015) Yosuke Kayama et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Exon Skipping Is Correlated with Exon Circularization

(2015) Steven Kelly et al.   JOURNAL OF MOLECULAR BIOLOGY

Long noncoding RNAs in cardiac development and ageing

(2015)   Nature Reviews Cardiology

Exon-intron circular RNAs regulate transcription in the nucleus

(2015) Zhaoyong Li et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

The Ll.LtrB intron fromLactococcus lactisexcises as circles in vivo: insights into the group II intron circularization pathway

(2015) Caroline Monat et al.   RNA

Exon-intron circular RNAs regulate transcription in the nucleus

(2015) Zhaoyong Li et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Circular RNA biogenesis can proceed through an exon-containing lariat precursor

(2015) Steven P Barrett et al.   eLife

Complementary Sequence-Mediated Exon Circularization

(2014) Xiao-Ou Zhang et al.   CELL

The Landscape of MicroRNA, Piwi-Interacting RNA, and Circular RNA in Human Saliva

(2014) J. H. Bahn et al.   CLINICAL CHEMISTRY

circRNA Biogenesis Competes with Pre-mRNA Splicing

(2014) Reut Ashwal-Fluss et al.   MOLECULAR CELL

miRNAs as biomarkers of myocardial infarction: a step forward towards personalized medicine?

(2014) Emeline Goretti et al.   TRENDS IN MOLECULAR MEDICINE

The pathogenesis of cardiac fibrosis

(2013) Ping Kong et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

MicroRNA-150

(2013) Yvan Devaux et al.   Circulation-Cardiovascular Genetics

Natural RNA circles function as efficient microRNA sponges

(2013) Thomas B. Hansen et al.   NATURE

Circular RNAs are a large class of animal RNAs with regulatory potency

(2013) Sebastian Memczak et al.   NATURE

Mst1 inhibits autophagy by promoting the interaction between Beclin1 and Bcl-2

(2013) Yasuhiro Maejima et al.   NATURE MEDICINE

Systems-Based Approaches to Cardiovascular Biomarker Discovery

(2012) Francisco J. Azuaje et al.   Circulation-Cardiovascular Genetics

An integrated encyclopedia of DNA elements in the human genome

(2012)   NATURE

Regression of pathological cardiac hypertrophy: Signaling pathways and therapeutic targets

(2012) Jianglong Hou et al.   PHARMACOLOGY & THERAPEUTICS

Inhibition of PKCα/β With Ruboxistaurin Antagonizes Heart Failure in Pigs After Myocardial Infarction Injury

(2011) Dennis Ladage et al.   CIRCULATION RESEARCH

Diabetic cardiomyopathy: understanding the molecular and cellular basis to progress in diagnosis and treatment

(2011) Inês Falcão-Pires et al.   HEART FAILURE REVIEWS

Classification of cell death: recommendations of the Nomenclature Committee on Cell Death 2009

(2008) G Kroemer et al.   CELL DEATH AND DIFFERENTIATION