A circular RNA protects the heart from pathological hypertrophy and heart failure by targeting miR-223

Early NADPH oxidase-2 activation is crucial in phenylephrine-induced hypertrophy of H9c2 cells

(2014) Nynke E. Hahn et al.   CELLULAR SIGNALLING

Involvement of peptidyl-prolyl isomerase Pin1 in the inhibitory effect of fluvastatin on endothelin-1-induced cardiomyocyte hypertrophy

(2014) Satoshi Sakai et al.   LIFE SCIENCES

Inhibition of Angiotensin II-Induced Cardiac Hypertrophy and Associated Ventricular Arrhythmias by a p21 Activated Kinase 1 Bioactive Peptide

(2014) Rui Wang et al.   PLoS One

Roles of cGMP-dependent protein kinase I (cGKI) and PDE5 in the regulation of Ang II-induced cardiac hypertrophy and fibrosis

(2014) E. Patrucco et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Circular Intronic Long Noncoding RNAs

(2013) Yang Zhang et al.   MOLECULAR CELL

Natural RNA circles function as efficient microRNA sponges

(2013) Thomas B. Hansen et al.   NATURE

Circular RNAs are a large class of animal RNAs with regulatory potency

(2013) Sebastian Memczak et al.   NATURE

microRNA-22 Promotes Heart Failure through Coordinate Suppression of PPAR/ERR-Nuclear Hormone Receptor Transcription

(2013) Priyatansh Gurha et al.   PLoS One

Chronic receptor-mediated activation of Gi/o proteins alters basal t-tubular and sarcolemmal L-type Ca2+ channel activity through phosphatases in heart failure

(2012) Toshihide Kashihara et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Interleukin-10 Treatment Attenuates Pressure Overload–Induced Hypertrophic Remodeling and Improves Heart Function via Signal Transducers and Activators of Transcription 3–Dependent Inhibition of Nuclear Factor-κB

(2012) Suresh Kumar Verma et al.   CIRCULATION

Mir-24 Regulates Junctophilin-2 Expression in Cardiomyocytes

(2012) Ming Xu et al.   CIRCULATION RESEARCH

Circular RNAs are abundant, conserved, and associated with ALU repeats

(2012) W. R. Jeck et al.   RNA

A role for cardiotrophin-1 in myocardial remodeling induced by aldosterone

(2011) Natalia López-Andrés et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Cardiomyocyte overexpression of miR-27b induces cardiac hypertrophy and dysfunction in mice

(2011) Jian Wang et al.   CELL RESEARCH

A Critical Role for the Protein Apoptosis Repressor With Caspase Recruitment Domain in Hypoxia-Induced Pulmonary Hypertension

(2011) Ari L. Zaiman et al.   CIRCULATION

Attenuation of MicroRNA-22 derepressed PTEN to effectively protect rat cardiomyocytes from hypertrophy

(2011) Xu-Dong Xu et al.   JOURNAL OF CELLULAR PHYSIOLOGY

miR-24 inhibits apoptosis and represses Bim in mouse cardiomyocytes

(2011) Li Qian et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Experimental strategies for microRNA target identification

(2011) D. W. Thomson et al.   NUCLEIC ACIDS RESEARCH

Control of cardiovascular differentiation by microRNAs

(2010) Kisho Ohtani et al.   BASIC RESEARCH IN CARDIOLOGY

miR-223 and miR-142 attenuate hematopoietic cell proliferation and miR-223 positively regulates miR-142 through LMO2 isoforms and CEBP-β

(2010) Wei Sun et al.   CELL RESEARCH

MicroRNA-494 Targeting Both Proapoptotic and Antiapoptotic Proteins Protects Against Ischemia/Reperfusion-Induced Cardiac Injury

(2010) Xiaohong Wang et al.   CIRCULATION

MicroRNA-21 Is a Downstream Effector of AKT That Mediates Its Antiapoptotic Effects via Suppression of Fas Ligand

(2010) Danish Sayed et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

MicroRNAs in Cardiac Apoptosis

(2010) Peifeng Li   Journal of Cardiovascular Translational Research

miR-1 Overexpression Enhances Ca 2+ Release and Promotes Cardiac Arrhythmogenesis by Targeting PP2A Regulatory Subunit B56α and Causing CaMKII-Dependent Hyperphosphorylation of RyR2

(2009) Dmitry Terentyev et al.   CIRCULATION RESEARCH

Down-regulation of Catalase and Oxidative Modification of Protein Kinase CK2 Lead to the Failure of Apoptosis Repressor with Caspase Recruitment Domain to Inhibit Cardiomyocyte Hypertrophy

(2008) Iram Murtaza et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

MicroRNA-223 reversibly regulates erythroid and megakaryocytic differentiation of K562 cells

(2008) Jin-Yun Yuan et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

The impact of microRNAs on protein output

(2008) Daehyun Baek et al.   NATURE

Regulation of progenitor cell proliferation and granulocyte function by microRNA-223

(2008) Jonathan B. Johnnidis et al.   NATURE