Fluoride in the Central Nervous System and Its Potential Influence on the Development and Invasiveness of Brain Tumours—A Research Hypothesis

Changes in Gene and Protein Expression of Metalloproteinase-2 and -9 and Their Inhibitors TIMP2 and TIMP3 in Different Parts of Fluoride-Exposed Rat Brain

(2021) Agnieszka Łukomska et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

The value of the hedgehog signal in osteoblasts in fluoride-induced bone-tissue injury

(2021) Chaonan Deng et al.   Journal of Orthopaedic Surgery and Research

TGF-β Signaling Promotes Glioma Progression Through Stabilizing Sox9

(2021) Min Chao et al.   Frontiers in Immunology

Tumor Heterogeneity in Glioblastomas: From Light Microscopy to Molecular Pathology

(2021) Aline Becker et al.   Cancers

Iron at the Interface of Hepatocellular Carcinoma

(2021) Rossana Paganoni et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Perspective of mesenchymal transformation in glioblastoma

(2021) Yona Kim et al.   Acta Neuropathologica Communications

Synergistic Effect of Perampanel and Temozolomide in Human Glioma Cell Lines

(2021) Andrea Salmaggi et al.   Journal of Personalized Medicine

Long-term exposure to the fluoride blocks the development of chondrocytes in the ducks: The molecular mechanism of fluoride regulating autophagy and apoptosis

(2021) Yajing Wang et al.   ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY

Distributing and assessing fluoride health risk in urban drinking water resources in Fars Province, Iran, using the geographical information system

(2021) Masoud Ghanbarian et al.   ENVIRONMENTAL GEOCHEMISTRY AND HEALTH

Critical windows of fluoride neurotoxicity in Canadian children

(2021) Linda Farmus et al.   ENVIRONMENTAL RESEARCH

miR ‐486‐3p regulates CyclinD1 and promotes fluoride‐induced osteoblast proliferation and activation

(2021) Ting Ouyang et al.   ENVIRONMENTAL TOXICOLOGY

Selenium stimulates the antitumour immunity: Insights to future research

(2021) Ali Razaghi et al.   EUROPEAN JOURNAL OF CANCER

WNT Signaling as a Therapeutic Target for Glioblastoma

(2021) Michael Latour et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Recent advances in cellular effects of fluoride: an update on its signalling pathway and targeted therapeutic approaches

(2021) Apoorva H. Nagendra et al.   MOLECULAR BIOLOGY REPORTS

Urinary Fluoride Levels among Canadians with and without Community Water Fluoridation

(2021) Julia K. Riddell et al.   International Journal of Environmental Research and Public Health

Expression of Autophagy-Related Factors LC3A and Beclin 1 and Apoptosis-Related Factors Bcl-2 and BAX in Osteoblasts Treated With Sodium Fluoride

(2021) Lin Xu et al.   Frontiers in Physiology

Involvement of Thyroid Hormones in Brain Development and Cancer

(2021) Gabriella Schiera et al.   Cancers

Fluoride regulates chondrocyte proliferation and autophagy via PI3K/AKT/mTOR signaling pathway

(2021) Lan Ma et al.   CHEMICO-BIOLOGICAL INTERACTIONS

Co-exposure to fluoride and arsenic disrupts intestinal flora balance and induces testicular autophagy in offspring rats

(2021) Penghui Liu et al.   ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY

Progress of Signaling Pathways, Stress Pathways and Epigenetics in the Pathogenesis of Skeletal Fluorosis

(2021) Lichun Qiao et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Autophagy in animal development

(2020) Elizabeth A. Allen et al.   CELL DEATH AND DIFFERENTIATION

Inorganic fluoride and functions of brain

(2020) N. I. Agalakova et al.   CRITICAL REVIEWS IN TOXICOLOGY

The influence of environmental pollution with fluorine compounds on the level of fluoride in soil, feed and eggs of laying hens in Central Pomerania, Poland

(2020) Elżbieta Bombik et al.   ENVIRONMENTAL MONITORING AND ASSESSMENT

Fluoride exposure alters Ca2+ signaling and mitochondrial function in enamel cells

(2020) Francisco J. Aulestia et al.   Science Signaling

Toxicity of fluoride: critical evaluation of evidence for human developmental neurotoxicity in epidemiological studies, animal experiments and in vitro analyses

(2020) Sabine Guth et al.   ARCHIVES OF TOXICOLOGY

Fluoride Affects Dopamine Metabolism and Causes Changes in the Expression of Dopamine Receptors (D1R and D2R) in Chosen Brain Structures of Morphine-Dependent Rats

(2020) Patrycja Kupnicka et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Autophagy promotes immune evasion of pancreatic cancer by degrading MHC-I

(2020) Keisuke Yamamoto et al.   NATURE

Controversy: The evolving science of fluoride: when new evidence doesn’t conform with existing beliefs

(2020) Christine Till et al.   PEDIATRIC RESEARCH

Chronic Exposure to Fluoride Affects GSH Level and NOX4 Expression in Rat Model of This Element of Neurotoxicity

(2020) Karolina Dec et al.   Biomolecules

Hypothyroidism correlates with favourable survival prognosis in patients with brain metastatic cancer

(2020) Anna S. Berghoff et al.   EUROPEAN JOURNAL OF CANCER

Iron deficiency, immunology, and colorectal cancer

(2020) Oliver Phipps et al.   NUTRITION REVIEWS

NF-κB inhibitor with Temozolomide results in significant apoptosis in glioblastoma via the NF-κB(p65) and actin cytoskeleton regulatory pathways

(2020) Naze G. Avci et al.   Scientific Reports

Effects of low-level fluoride exposure on glucose homeostasis in female NOD mice

(2020) Juliana Sanches Trevizol et al.   CHEMOSPHERE

Effects of Fluoride Long-Term Exposure over the Cerebellum: Global Proteomic Profile, Oxidative Biochemistry, Cell Density, and Motor Behavior Evaluation

(2020) Géssica Oliveira Lopes et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Combined inhibition of JAK2-STAT3 and SMO-GLI1/tGLI1 pathways suppresses breast cancer stem cells, tumor growth, and metastasis

(2020) Daniel Doheny et al.   ONCOGENE

Importance of Dietary Phosphorus for Bone Metabolism and Healthy Aging

(2020) Juan Serna et al.   Nutrients

Fluoride Risk Assessment from Consumption of Different Foods Commercialized in a European Region

(2020) Juan R. Jaudenes et al.   Applied Sciences-Basel

Mechanisms of Fluoride Toxicity: From Enzymes to Underlying Integrative Networks

(2020) Anna Strunecka et al.   Applied Sciences-Basel

In Vitro Evaluation of the Apoptotic, Autophagic, and Necrotic Molecular Pathways of Fluoride

(2020) F. Urut et al.   BIOLOGICAL TRACE ELEMENT RESEARCH

Interleukin 17A deficiency alleviates fluoride-induced testicular injury by inhibiting the immune response and apoptosis

(2020) Yanyan Li et al.   CHEMOSPHERE

Antioxidant Effect of Propofol in Gliomas and Its Association With Divalent Metal Transporter 1

(2020) Chenyi Yang et al.   Frontiers in Oncology

Effect of exercise on microglial activation and transcriptome of hippocampus in fluorosis mice

(2020) Jixiang Wang et al.   SCIENCE OF THE TOTAL ENVIRONMENT

Role of Notch Signaling Pathway in Glioblastoma Multiforme Pathogenesis

(2019) Riccardo Bazzoni et al.   Cancers

Aluminium and fluoride in drinking water in relation to later dementia risk

(2019) Tom C. Russ et al.   BRITISH JOURNAL OF PSYCHIATRY

Autophagy May Be Involved in Fluoride-Induced Learning Impairment in Rats

(2019) Chengzhi Zhang et al.   BIOLOGICAL TRACE ELEMENT RESEARCH

Glioblastoma vs temozolomide: can the red queen race be won?

(2019) Anjali Arora et al.   CANCER BIOLOGY & THERAPY

Exposure to fluoride aggravates the impairment in learning and memory and neuropathological lesions in mice carrying the APP/PS1 double-transgenic mutation

(2019) Kun Cao et al.   Alzheimers Research & Therapy

Acquired temozolomide resistance in MGMT-deficient glioblastoma cells is associated with regulation of DNA repair by DHC2

(2019) Guo-zhong Yi et al.   BRAIN

Matrix metalloproteinases in the CNS: interferons get nervous

(2019) Sameeksha Chopra et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Effects of Perinatal Fluoride Exposure on Short- and Long-Term Memory, Brain Antioxidant Status, and Glutamate Metabolism of Young Rat Pups

(2019) Mariana Bartos et al.   INTERNATIONAL JOURNAL OF TOXICOLOGY

Harnessing Microglia and Macrophages for the Treatment of Glioblastoma

(2019) Ioanna Prionisti et al.   Frontiers in Pharmacology

Non-canonical Hedgehog Signaling Pathway in Cancer: Activation of GLI Transcription Factors Beyond Smoothened

(2019) Silvia Pietrobono et al.   Frontiers in Genetics

TGLI1 transcription factor mediates breast cancer brain metastasis via activating metastasis-initiating cancer stem cells and astrocytes in the tumor microenvironment

(2019) Sherona R. Sirkisoon et al.   ONCOGENE

Effects of long-term fluoride exposure on cognitive ability and the underlying mechanisms: Role of autophagy and its association with apoptosis

(2019) Guoyu Zhou et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

High Glucose Promotes Human Glioblastoma Cell Growth by Increasing the Expression and Function of Chemoattractant and Growth Factor Receptors

(2019) Zhiyao Bao et al.   Translational Oncology

Association Between Maternal Fluoride Exposure During Pregnancy and IQ Scores in Offspring in Canada

(2019) Rivka Green et al.   JAMA Pediatrics

Trace Element Concentration Changes in Brain Tumors: A Review

(2019) Karen Cilliers et al.   Anatomical Record-Advances in Integrative Anatomy and Evolutionary Biology

Increased expression of MMP-2 and MMP-9 indicates poor prognosis in glioma recurrence

(2019) Wei Zhou et al.   BIOMEDICINE & PHARMACOTHERAPY

Nuclear factor I A promotes temozolomide resistance in glioblastoma via activation of nuclear factor κB pathway

(2019) Xiao Yu et al.   LIFE SCIENCES

Changes of O6-Methylguanine DNA Methyltransferase (MGMT) Promoter Methylation in Glioblastoma Relapse—A Meta-Analysis Type Literature Review

(2019) Jonas Feldheim et al.   Cancers

Deregulation of autophagy is involved in nephrotoxicity of arsenite and fluoride exposure during gestation to puberty in rat offspring

(2019) Xiaolin Tian et al.   ARCHIVES OF TOXICOLOGY

Cognitive Decline of Rats with Chronic Fluorosis Is Associated with Alterations in Hippocampal Calpain Signaling

(2019) Olga V. Nadei et al.   BIOLOGICAL TRACE ELEMENT RESEARCH

Aberrant DNA methylation of Cyclind-CDK4-p21 is associated with chronic fluoride poisoning

(2019) Xueli Pan et al.   CHEMICO-BIOLOGICAL INTERACTIONS

Effect of arsenic and/or fluoride gestational exposure on renal autophagy in offspring mice

(2019) Qiang Guo et al.   CHEMOSPHERE

Developmental fluoride neurotoxicity: an updated review

(2019) Philippe Grandjean   Environmental Health

Fluorosis and cognitive development among children (6–14 years of age) in the endemic areas of the world: a review and critical analysis

(2019) Muhammad Saeed et al.   ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH

Excessive ER stress and the resulting autophagic flux dysfunction contribute to fluoride-induced neurotoxicity

(2018) Qiang Niu et al.   ENVIRONMENTAL POLLUTION

TGF-β1 acts as mediator in fluoride-induced autophagy in the mouse osteoblast cells

(2018) Yangfei Zhao et al.   FOOD AND CHEMICAL TOXICOLOGY

Role of Microenvironment in Glioma Invasion: What We Learned from In Vitro Models

(2018) Ivana Manini et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Fluoride Exposure in Early Life as the Possible Root Cause of Disease In Later Life

(2018) Tetsuo Nakamoto et al.   Journal of Clinical Pediatric Dentistry

IGF1 receptor signaling pathways

(2018) Fumihiko Hakuno et al.   JOURNAL OF MOLECULAR ENDOCRINOLOGY

Fluoride induced tissue hypercalcemia, IL-17 mediated inflammation and apoptosis lead to cardiomyopathy: Ultrastructural and biochemical findings

(2018) Javed Ahsan Quadri et al.   TOXICOLOGY

Fluoride induces apoptosis via inhibiting SIRT1 activity to activate mitochondrial p53 pathway in human neuroblastoma SH-SY5Y cells

(2018) Wei Tu et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

CAT3, a prodrug of 13a(S)-3-hydroxyl-6,7-dimethoxyphenanthro[9,10-b]-indolizidine, circumvents temozolomide-resistant glioblastoma via the Hedgehog signaling pathway, independently of O6-methylguanine DNA methyltransferase expression

(2018) Ming Ji et al.   OncoTargets and Therapy

Impact of Drinking Water Fluoride on Human Thyroid Hormones: A Case- Control Study

(2018) Zohreh Kheradpisheh et al.   Scientific Reports

The mode and dynamics of glioblastoma cell invasion into a decellularized tissue-derived extracellular matrix-based three-dimensional tumor model

(2018) IlKyoo Koh et al.   Scientific Reports

PRL-3 is a potential glioblastoma prognostic marker and promotes glioblastoma progression by enhancing MMP7 through the ERK and JNK pathways

(2018) Nan Mu et al.   Theranostics

Sodium fluoride induces splenocyte autophagy via the mammalian targets of rapamycin (mTOR) signaling pathway in growing mice

(2018) Ping Kuang et al.   Aging-US

Iron and Cancer

(2018) Suzy V. Torti et al.   Annual Review of Nutrition

Fluoride induces apoptosis and autophagy through the IL-17 signaling pathway in mice hepatocytes

(2018) Yangfei Zhao et al.   ARCHIVES OF TOXICOLOGY

Sodium Fluoride (NaF) Induces Inflammatory Responses Via Activating MAPKs/NF-κB Signaling Pathway and Reducing Anti-inflammatory Cytokine Expression in the Mouse Liver

(2018) Linlin Chen et al.   BIOLOGICAL TRACE ELEMENT RESEARCH

CBTRUS Statistical Report: Primary Brain and Other Central Nervous System Tumors Diagnosed in the United States in 2011–2015

(2018) Quinn T Ostrom et al.   NEURO-ONCOLOGY

Fluoride activates microglia, secretes inflammatory factors and influences synaptic neuron plasticity in the hippocampus of rats

(2018) Li Yang et al.   NEUROTOXICOLOGY

PDGF-mediated mesenchymal transformation renders endothelial resistance to anti-VEGF treatment in glioblastoma

(2018) Tianrun Liu et al.   Nature Communications

NF-κB, Mesenchymal Differentiation and Glioblastoma

(2018) Bakhtiar Yamini   Cells

Sodium fluoride induces apoptosis and autophagy via the endoplasmic reticulum stress pathway in MC3T3-E1 osteoblastic cells

(2018) Xueyan Li et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

Prenatal Fluoride Exposure and Cognitive Outcomes in Children at 4 and 6–12 Years of Age in Mexico

(2017) Morteza Bashash et al.   ENVIRONMENTAL HEALTH PERSPECTIVES

Interplay of autophagy, receptor tyrosine kinase signalling and endocytic trafficking

(2017) Jane Fraser et al.   Essays in Biochemistry

Maternal fluoride exposure during gestation and lactation decreased learning and memory ability, and glutamate receptor mRNA expressions of mouse pups

(2017) Z Sun et al.   HUMAN & EXPERIMENTAL TOXICOLOGY

Fluoride Induces Neuroinflammation and Alters Wnt Signaling Pathway in BV2 Microglial Cells

(2017) Rui Chen et al.   INFLAMMATION

Vesicular melatonin efficiently downregulates sodium fluoride-induced rat hepato- and broncho- TNF-α, TGF-β expressions, and associated oxidative injury: a comparative study of liposomal and nanoencapsulated forms

(2017) Suvomoy Sana et al.   International Journal of Nanomedicine

Fluoride-Induced Autophagy via the Regulation of Phosphorylation of Mammalian Targets of Rapamycin in Mice Leydig Cells

(2017) Jianhai Zhang et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

The biology and mathematical modelling of glioma invasion: a review

(2017) J. C. L. Alfonso et al.   Journal of the Royal Society Interface

Autophagy: The spotlight for cellular stress responses

(2017) Palaniyandi Ravanan et al.   LIFE SCIENCES

Fluoride Alteration of [3H]Glucose Uptake in Wistar Rat Brain and Peripheral Tissues

(2017) Anna Rogalska et al.   NEUROTOXICITY RESEARCH

IL-33 enhances glioma cell migration and invasion by upregulation of MMP2 and MMP9 via the ST2-NF-κB pathway

(2017) Jian-Fei Zhang et al.   ONCOLOGY REPORTS

Modulation of MMP-2 and MMP-9 secretion by cytokines, inducers and inhibitors in human glioblastoma T-98G cells

(2017) M. Waheed Roomi et al.   ONCOLOGY REPORTS

Epigenetics in cancer: Fundamentals and Beyond

(2017) Subhankar Biswas et al.   PHARMACOLOGY & THERAPEUTICS

Correction: Fluoride Regulate Osteoblastic Transforming Growth Factor-β1 Signaling by Mediating Recycling of the Type I Receptor ALK5

(2017) Chen Yang et al.   PLoS One

Propofol inhibits invasion and proliferation of C6 glioma cells by regulating the Ca 2+ permeable AMPA receptor-system x c − pathway

(2017) Xin-yue Wang et al.   TOXICOLOGY IN VITRO

Notch1 ablation radiosensitizes glioblastoma cells

(2017) Na Han et al.   Oncotarget

Sodium fluoride induces renal inflammatory responses by activating NF-κB signaling pathway and reducing anti-inflammatory cytokine expression in mice

(2017) Qin Luo et al.   Oncotarget

Sodium fluoride induces apoptosis in mouse splenocytes by activating ROS-dependent NF-κB signaling

(2017) Huidan Deng et al.   Oncotarget

Caspase-8 contributes to angiogenesis and chemotherapy resistance in glioblastoma

(2017) Giulia Fianco et al.   eLife

Fluoride caused thyroid endocrine disruption in male zebrafish (Danio rerio)

(2016) Chen Jianjie et al.   AQUATIC TOXICOLOGY

Preliminary Analysis of MicroRNAs Expression Profiling in MC3T3-E1 Cells Exposed to Fluoride

(2016) Yan Wang et al.   BIOLOGICAL TRACE ELEMENT RESEARCH

Wnt5a Drives an Invasive Phenotype in Human Glioblastoma Stem-like Cells

(2016) Elena Binda et al.   CANCER RESEARCH

Regulation of LPS-induced mRNA expression of pro-inflammatory cytokines via alteration of NF-κB activity in mouse peritoneal macrophages exposed to fluoride

(2016) Yuhu Tian et al.   CHEMOSPHERE

Fluoride exposure changed the structure and the expressions of Y chromosome related genes in testes of mice

(2016) Jinling Cao et al.   CHEMOSPHERE

GANT61, a GLI inhibitor, sensitizes glioma cells to the temozolomide treatment

(2016) Jianlong Li et al.   JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

Community water fluoridation predicts increase in age-adjusted incidence and prevalence of diabetes in 22 states from 2005 and 2010

(2016) K. Fluegge   JOURNAL OF WATER AND HEALTH

Iron speciation, ferritin concentrations and Fe : ferritin ratios in different malignant breast cancer cell lines: on the search for cancer biomarkers

(2016) J. Alonso García et al.   Metallomics

Phenotypic Transition as a Survival Strategy of Glioma

(2016) Tomotsugu ICHIKAWA et al.   NEUROLOGIA MEDICO-CHIRURGICA

Beta 1-integrin–c-Met cooperation reveals an inside-in survival signalling on autophagy-related endomembranes

(2016) Rachel Barrow-McGee et al.   Nature Communications

SIRT1-mediated FoxOs pathways protect against apoptosis by promoting autophagy in osteoblast-like MC3T3-E1 cells exposed to sodium fluoride

(2016) Xiaolong Gu et al.   Oncotarget

Targeting NF- B in glioblastoma: A therapeutic approach

(2016) D. Friedmann-Morvinski et al.   Science Advances

Community Water Fluoridation and Intelligence: Prospective Study in New Zealand

(2015) Jonathan M. Broadbent et al.   AMERICAN JOURNAL OF PUBLIC HEALTH

Hepatotoxicity Induced by Subchronic Exposure of Fluoride and Chlorpyrifos in Wistar Rats: Mitigating Effect of Ascorbic Acid

(2015) Rajinder Raina et al.   BIOLOGICAL TRACE ELEMENT RESEARCH

Mechanisms regulating glioma invasion

(2015) Ivy Paw et al.   CANCER LETTERS

Fluoride exposure changed the structure and the expressions of reproductive related genes in the hypothalamus–pituitary–testicular axis of male mice

(2015) Haijun Han et al.   CHEMOSPHERE

Elevated expression of Notch-1 and EGFR induced apoptosis in glioblastoma multiforme patients

(2015) Zhen-yi Xing et al.   CLINICAL NEUROLOGY AND NEUROSURGERY

Hormony tarczycy w ośrodkowym układzie nerwowym (OUN) i ich wpływ na nowotworzenie, zwłaszcza na rozwój i przebieg glioblastoma multiforme — hipoteza badawcza

(2015) Paweł Nauman   Endokrynologia Polska

Fluoride in the environment: sources, distribution and defluoridation

(2015) Meththika Vithanage et al.   Environmental Chemistry Letters

Exposure to fluoridated water and attention deficit hyperactivity disorder prevalence among children and adolescents in the United States: an ecological association

(2015) Ashley J Malin et al.   Environmental Health

Inhibitory effect of iron withdrawal by chelation on the growth of human and murine mammary carcinoma and fibrosarcoma cells

(2015) Melanie R. Power Coombs et al.   EXPERIMENTAL AND MOLECULAR PATHOLOGY

Effects of 3,3',5-triiodothyronine on microglial functions

(2015) Yuki Mori et al.   GLIA

The role for autophagy in cancer

(2015) Eileen White   JOURNAL OF CLINICAL INVESTIGATION

Low-Level Fluoride Exposure Increases Insulin Sensitivity in Experimental Diabetes

(2015) J.G.V.M. Lobo et al.   JOURNAL OF DENTAL RESEARCH

Role of inhibition of osteogenesis function by Sema4D/Plexin-B1 signaling pathway in skeletal fluorosis in vitro

(2015) Xiao-li Liu et al.   Journal of Huazhong University of Science and Technology-Medical Sciences

Quantitative imaging of magnesium distribution at single-cell resolution in brain tumors and infiltrating tumor cells with secondary ion mass spectrometry (SIMS)

(2015) Subhash Chandra et al.   JOURNAL OF NEURO-ONCOLOGY

WNT signaling in glioblastoma and therapeutic opportunities

(2015) Yeri Lee et al.   LABORATORY INVESTIGATION

Fluoride-Induced Neuron Apoptosis and Expressions of Inflammatory Factors by Activating Microglia in Rat Brain

(2015) Nan Yan et al.   MOLECULAR NEUROBIOLOGY

Insulin-mediated signaling promotes proliferation and survival of glioblastoma through Akt activation

(2015) Yuanying Gong et al.   NEURO-ONCOLOGY

American Brain Tumor Association Adolescent and Young Adult Primary Brain and Central Nervous System Tumors Diagnosed in the United States in 2008-2012

(2015) Quinn T. Ostrom et al.   NEURO-ONCOLOGY

Survival and low-grade glioma: the emergence of genetic information

(2015) Elizabeth B. Claus et al.   Neurosurgical Focus

X-ray fluorescence study of the concentration of selected trace and minor elements in human brain tumours

(2015) Aleksandra Wandzilak et al.   SPECTROCHIMICA ACTA PART B-ATOMIC SPECTROSCOPY

Modifying Effect of COMT Gene Polymorphism and a Predictive Role for Proteomics Analysis in Children’s Intelligence in Endemic Fluorosis Area in Tianjin, China

(2015) Shun Zhang et al.   TOXICOLOGICAL SCIENCES

Fluoride as a factor initiating and potentiating inflammation in THP1 differentiated monocytes/macrophages

(2015) I. Gutowska et al.   TOXICOLOGY IN VITRO

NF-κB inhibitor reverses temozolomide resistance in human glioma TR/U251 cells

(2015) XUAN WANG et al.   Oncology Letters

Wnt/β-catenin pathway regulates MGMT gene expression in cancer and inhibition of Wnt signalling prevents chemoresistance

(2015) Malin Wickström et al.   Nature Communications

The NFκB pathway: a therapeutic target in glioblastoma

(2015) Lorena Nogueira et al.   Oncotarget

NF-κB and STAT3 in glioblastoma: therapeutic targets coming of age

(2014) G Kenneth Gray et al.   Expert Review of Neurotherapeutics

Fluoride Affects Enamel Protein Content via TGF-β1-mediated KLK4 Inhibition

(2014) M. Suzuki et al.   JOURNAL OF DENTAL RESEARCH

Effects of chronic fluoride intake on the antioxidant systems of the liver and kidney in rats

(2014) Flavia Godoy Iano et al.   JOURNAL OF FLUORINE CHEMISTRY

A neurocentric perspective on glioma invasion

(2014) Vishnu Anand Cuddapah et al.   NATURE REVIEWS NEUROSCIENCE

Single-cell RNA-seq highlights intratumoral heterogeneity in primary glioblastoma

(2014) A. P. Patel et al.   SCIENCE

Protein and mRNA expression of Shh, Smo and Gli1 and inhibition by cyclopamine in hepatocytes of rats with chronic fluorosis

(2014) Lina Zhao et al.   TOXICOLOGY LETTERS

Nanotetrac targets integrin αvβ3 on tumor cells to disorder cell defense pathways and block angiogenesis

(2014) Paul Davis et al.   OncoTargets and Therapy

Active CREB1 Promotes a Malignant TGF 2 Autocrine Loop in Glioblastoma

(2014) L. Rodon et al.   Cancer Discovery

A comparative study of fluoride ingestion levels, serum thyroid hormone & TSH level derangements, dental fluorosis status among school children from endemic and non-endemic fluorosis areas

(2014) Navneet Singh et al.   SpringerPlus

Glioblastoma Multiforme: A Look Inside Its Heterogeneous Nature

(2014) Maria-del-Mar Inda et al.   Cancers

Long-term response in high-grade optic glioma treated with medically induced hypothyroidism and carboplatin

(2013) Osnat Ashur-Fabian et al.   ANTI-CANCER DRUGS

Sirtuin1 and autophagy protect cells from fluoride-induced cell stress

(2013) Maiko Suzuki et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Change of urinary fluoride and bone metabolism indicators in the endemic fluorosis areas of southern china after supplying low fluoride public water

(2013) Shaoxian Chen et al.   BMC PUBLIC HEALTH

Mesenchymal Differentiation Mediated by NF-κB Promotes Radiation Resistance in Glioblastoma

(2013) Krishna P.L. Bhat et al.   CANCER CELL

The GLI1 splice variant TGLI1 promotes glioblastoma angiogenesis and growth

(2013) Hu Zhu et al.   CANCER LETTERS

Are pediatric brain tumors on the rise in the USA? Significant incidence and survival findings from the SEER database analysis

(2013) Swetal Patel et al.   CHILDS NERVOUS SYSTEM

Assessment of relationship on excess fluoride intake from drinking water and carotid atherosclerosis development in adults in fluoride endemic areas, China

(2013) Hui Liu et al.   INTERNATIONAL JOURNAL OF HYGIENE AND ENVIRONMENTAL HEALTH

Physical exercise ameliorates the toxic effect of fluoride on the insulin–glucose system

(2013) Mercedes Lombarte et al.   JOURNAL OF ENDOCRINOLOGY

JNK and NADPH Oxidase Involved in Fluoride-Induced Oxidative Stress in BV-2 Microglia Cells

(2013) Ling Yan et al.   MEDIATORS OF INFLAMMATION

Activation of the NF-κB Pathway by the STAT3 Inhibitor JSI-124 in Human Glioblastoma Cells

(2013) Braden C. McFarland et al.   MOLECULAR CANCER RESEARCH

Physiology of Blood–Brain Interfaces in Relation to Brain Disposition of Small Compounds and Macromolecules

(2013) N. Strazielle et al.   MOLECULAR PHARMACEUTICS

Low Glucose Utilization and Neurodegenerative Changes Caused by Sodium Fluoride Exposure in Rat’s Developmental Brain

(2013) Chunyang Jiang et al.   NEUROMOLECULAR MEDICINE

Targeting Notch signaling pathway in cancer: Clinical development advances and challenges

(2013) Naoko Takebe et al.   PHARMACOLOGY & THERAPEUTICS

Bmi-1 Promotes Glioma Angiogenesis by Activating NF-κB Signaling

(2013) Lili Jiang et al.   PLoS One

Matrix metalloproteinases in cancer: their value as diagnostic and prognostic markers and therapeutic targets

(2013) Elin Hadler-Olsen et al.   TUMOR BIOLOGY

The “go or grow” potential of gliomas is linked to the neuropeptide processing enzyme carboxypeptidase E and mediated by metabolic stress

(2012) Elisabeth Höring et al.   ACTA NEUROPATHOLOGICA

Effect of Fluoride on Insulin Level of Rats and Insulin Receptor Expression in the MC3T3-E1 Cells

(2012) Chun-yan Hu et al.   BIOLOGICAL TRACE ELEMENT RESEARCH

The Influence of Fluoride on the Expression of Inhibitors of Wnt/β-Catenin Signaling Pathway in Rat Skin Fibroblast Cells

(2012) Xiao-Li Liu et al.   BIOLOGICAL TRACE ELEMENT RESEARCH

Interleukins in glioblastoma pathophysiology: implications for therapy

(2012) YT Yeung et al.   BRITISH JOURNAL OF PHARMACOLOGY

Activation of canonical WNT/β-catenin signaling enhances in vitro motility of glioblastoma cells by activation of ZEB1 and other activators of epithelial-to-mesenchymal transition

(2012) Ulf D. Kahlert et al.   CANCER LETTERS

TGF-β signaling and epithelial–mesenchymal transition in cancer progression

(2012) Yoko Katsuno et al.   CURRENT OPINION IN ONCOLOGY

Wnt-RhoA signaling is involved in dental enamel development

(2012) Li Peng et al.   EUROPEAN JOURNAL OF ORAL SCIENCES

Tumor-Associated Microglia/Macrophages Enhance the Invasion of Glioma Stem-like Cells via TGF- 1 Signaling Pathway

(2012) X.-z. Ye et al.   JOURNAL OF IMMUNOLOGY

p38 MAPK inhibitors attenuate pro-inflammatory cytokine production and the invasiveness of human U251 glioblastoma cells

(2012) Yiu To Yeung et al.   JOURNAL OF NEURO-ONCOLOGY

A Role of Fluoride on Free Radical Generation and Oxidative Stress in BV-2 Microglia Cells

(2012) Xi Shuhua et al.   MEDIATORS OF INFLAMMATION

Notch1 promotes glioma cell migration and invasion by stimulating β-catenin and NF-κB signaling via AKT activation

(2011) Xiaohua Zhang et al.   CANCER SCIENCE

Excessıve fluorıde ıntake alters the MMP-2, TIMP-1 and TGF-β levels of perıodontal soft tıssues: an experımental study ın rabbıts

(2011) Müge Lütfioğlu et al.   Clinical Oral Investigations

A multigene predictor of outcome in glioblastoma

(2011) H. Colman et al.   NEURO-ONCOLOGY

COX-2 regulates the proliferation of glioma stem like cells

(2011) Vivek Sharma et al.   NEUROCHEMISTRY INTERNATIONAL

Effect of Fluoridated Water on Plasma Insulin Levels and Glucose Homeostasis in Rats with Renal Deficiency

(2010) Maela Lupo et al.   BIOLOGICAL TRACE ELEMENT RESEARCH

Wnt-5a signaling is correlated with infiltrative activity in human glioma by inducing cellular migration and MMP-2

(2010) Masayuki Kamino et al.   CANCER SCIENCE

microRNA-451: A conditional switch controlling glioma cell proliferation and migration

(2010) Jakub Godlewski et al.   CELL CYCLE

Non-canonical NF-κB signaling pathway

(2010) Shao-Cong Sun   CELL RESEARCH

An Updated Overview on Wnt Signaling Pathways

(2010) Tata Purushothama Rao et al.   CIRCULATION RESEARCH

The Human Glioma-Associated Oncogene Homolog 1 (GLI1) Family of Transcription Factors in Gene Regulation and Diseases

(2010) Hu Zhu et al.   CURRENT GENOMICS

Effect of fluoride on calcium ion concentration and expression of nuclear transcription factor kappa-B ρ65 in rat hippocampus

(2010) Jing Zhang et al.   EXPERIMENTAL AND TOXICOLOGIC PATHOLOGY

Glutamate and the biology of gliomas

(2010) John de Groot et al.   GLIA

Comparative study of p38 MAPK signal transduction pathway of peripheral blood mononuclear cells from patients with coal-combustion-type fluorosis with and without high hair selenium levels

(2010) Qun Chen et al.   INTERNATIONAL JOURNAL OF HYGIENE AND ENVIRONMENTAL HEALTH

MicroRNA-451 Regulates LKB1/AMPK Signaling and Allows Adaptation to Metabolic Stress in Glioma Cells

(2010) Jakub Godlewski et al.   MOLECULAR CELL

Sonic Hedgehog/GLI1 signaling pathway inhibition restricts cell migration and invasion in human gliomas

(2010) Ke Wang et al.   NEUROLOGICAL RESEARCH

Selective targeting of radiation-resistant tumor-initiating cells

(2010) Mei Zhang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Effects of the Fas/Fas-L pathway on fluoride-induced apoptosis in SH-SY5Y cells

(2009) Bayi Xu et al.   ENVIRONMENTAL TOXICOLOGY

The GluR2 subunit inhibits proliferation by inactivating Src-MAPK signalling and induces apoptosis by means of caspase 3/6-dependent activation in glioma cells

(2009) Francesca Beretta et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Alterations of nAChRs and ERK1/2 in the brains of rats with chronic fluorosis and their connections with the decreased capacity of learning and memory

(2009) Yan-Jie Liu et al.   TOXICOLOGY LETTERS

Elevated copper and oxidative stress in cancer cells as a target for cancer treatment

(2008) Anshul Gupte et al.   CANCER TREATMENT REVIEWS

Inflammatory cytokine modulation of matrix metalloproteinase expression and invasiveness of glioma cells in a 3-dimensional collagen matrix

(2008) Susobhan Sarkar et al.   JOURNAL OF NEURO-ONCOLOGY

AMPA receptors promote perivascular glioma invasion via β1 integrin–dependent adhesion to the extracellular matrix

(2008) Yuji Piao et al.   NEURO-ONCOLOGY

Effects of fluoride on DNA damage, S-phase cell-cycle arrest and the expression of NF-κB in primary cultured rat hippocampal neurons

(2008) Ming Zhang et al.   TOXICOLOGY LETTERS