TGLI1 transcription factor mediates breast cancer brain metastasis via activating metastasis-initiating cancer stem cells and astrocytes in the tumor microenvironment

Truncated Glioma-Associated Oncogene Homolog 1 (tGLI1) Mediates Mesenchymal Glioblastoma via Transcriptional Activation of CD44

(2018) Tadas K. Rimkus et al.   CANCER RESEARCH

Interaction between STAT3 and GLI1/tGLI1 oncogenic transcription factors promotes the aggressiveness of triple-negative breast cancers and HER2-enriched breast cancer

(2018) Sherona R. Sirkisoon et al.   ONCOGENE

FGFR4 provides the conduit to facilitate FGF19 signaling in breast cancer progression

(2018) Xiangdong Zhao et al.   MOLECULAR CARCINOGENESIS

GLI2 promotes cell proliferation and migration through transcriptional activation of ARHGEF16 in human glioma cells

(2018) Dengliang Huang et al.   JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

Expression of embryonal stem cell transcription factors in breast cancer: Oct4 as an indicator for poor clinical outcome and tamoxifen resistance

(2017) Jae Moon Gwak et al.   Oncotarget

The Pluripotency Factor NANOG Binds to GLI Proteins and Represses Hedgehog-mediated Transcription

(2016) Qiang Li et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Identification of Distinct Breast Cancer Stem Cell Populations Based on Single-Cell Analyses of Functionally Enriched Stem and Progenitor Pools

(2016) Nina Akrap et al.   Stem Cell Reports

A transcription/translation-based gene signature predicts resistance to chemotherapy in breast cancer

(2015) Dong-Xu He et al.   JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS

Aberrant hedgehog signaling is responsible for the highly invasive behavior of a subpopulation of hepatoma cells

(2015) Y-H Fan et al.   ONCOGENE

Cancer stem cell targeted therapy: progress amid controversies

(2015) Tao Wang et al.   Oncotarget

The gain-of-function GLI1 transcription factor TGLI1 enhances expression of VEGF-C and TEM7 to promote glioblastoma angiogenesis

(2015) Richard L. Carpenter et al.   Oncotarget

Gli1-Mediated Regulation of Sox2 Facilitates Self-Renewal of Stem-Like Cells and Confers Resistance to EGFR Inhibitors in Non–Small Cell Lung Cancer

(2015) Namrata Bora-Singhal et al.   NEOPLASIA

The Molecular Signatures Database Hallmark Gene Set Collection

(2015) Arthur Liberzon et al.   Cell Systems

Overexpression of Oct4 suppresses the metastatic potential of breast cancer cells via Rnd1 downregulation

(2014) Long Shen et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Treatment outcomes and prognostic factors for patients with brain metastases from breast cancer of each subtype: a multicenter retrospective analysis

(2014) Naoki Niikura et al.   BREAST CANCER RESEARCH AND TREATMENT

Pazopanib Inhibits the Activation of PDGFRβ-Expressing Astrocytes in the Brain Metastatic Microenvironment of Breast Cancer Cells

(2013) Brunilde Gril et al.   AMERICAN JOURNAL OF PATHOLOGY

The GLI1 splice variant TGLI1 promotes glioblastoma angiogenesis and growth

(2013) Hu Zhu et al.   CANCER LETTERS

A Renewable Tissue Resource of Phenotypically Stable, Biologically and Ethnically Diverse, Patient-Derived Human Breast Cancer Xenograft Models

(2013) X. Zhang et al.   CANCER RESEARCH

Distinct Lineage Specification Roles for NANOG, OCT4, and SOX2 in Human Embryonic Stem Cells

(2012) Zheng Wang et al.   Cell Stem Cell

A CD44−/CD24+ phenotype is a poor prognostic marker in early invasive breast cancer

(2011) Mohamed A. H. Ahmed et al.   BREAST CANCER RESEARCH AND TREATMENT

MicroRNA history: Discovery, recent applications, and next frontiers

(2011) Maria I. Almeida et al.   MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS

Upregulation of VEGF-A and CD24 gene expression by the tGLI1 transcription factor contributes to the aggressive behavior of breast cancer cells

(2011) X Cao et al.   ONCOGENE

Oct4-Induced Reprogramming Is Required for Adult Brain Neural Stem Cell Differentiation into Midbrain Dopaminergic Neurons

(2011) Michela Deleidi et al.   PLoS One

Capturing Changes in the Brain Microenvironment during Initial Steps of Breast Cancer Brain Metastasis

(2010) Mihaela Lorger et al.   AMERICAN JOURNAL OF PATHOLOGY

A Novel Splice Variant of GLI1 That Promotes Glioblastoma Cell Migration and Invasion

(2009) H.-W. Lo et al.   CANCER RESEARCH

Genes that mediate breast cancer metastasis to the brain

(2009) Paula D. Bos et al.   NATURE

Expression of Fgf15 is regulated by both activator and repressor forms of Gli2 in vitro

(2008) Munekazu Komada et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Subtypes of Breast Cancer Show Preferential Site of Relapse

(2008) M. Smid et al.   CANCER RESEARCH