Lipid Peroxidation and Iron Metabolism: Two Corner Stones in the Homeostasis Control of Ferroptosis

Bufotalin induces ferroptosis in non-small cell lung cancer cells by facilitating the ubiquitination and degradation of GPX4

(2022) Wen Zhang et al.   FREE RADICAL BIOLOGY AND MEDICINE

Interaction between macrophages and ferroptosis

(2022) Yan Yang et al.   Cell Death & Disease

A targetable CoQ-FSP1 axis drives ferroptosis- and radiation-resistance in KEAP1 inactive lung cancers

(2022) Pranavi Koppula et al.   Nature Communications

Growth Differentiation Factor 15 Regulates Oxidative Stress-Dependent Ferroptosis Post Spinal Cord Injury by Stabilizing the p62-Keap1-Nrf2 Signaling Pathway

(2022) Mingjie Xia et al.   Frontiers in Aging Neuroscience

Ferroptosis: mechanisms, biology and role in disease

(2021) Xuejun Jiang et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Characteristics and Biomarkers of Ferroptosis

(2021) Xin Chen et al.   Frontiers in Cell and Developmental Biology

Heme Oxgenase-1, a Cardinal Modulator of Regulated Cell Death and Inflammation

(2021) Stefan W. Ryter   Cells

Mitochondrial ferritin attenuates cerebral ischaemia/reperfusion injury by inhibiting ferroptosis

(2021) Peina Wang et al.   Cell Death & Disease

Mitochondrial regulation of ferroptosis

(2021) Boyi Gan   JOURNAL OF CELL BIOLOGY

The lysosome as a master regulator of iron metabolism

(2021) Francesca Rizzollo et al.   TRENDS IN BIOCHEMICAL SCIENCES

GDF15: an emerging modulator of immunity and a strategy in COVID-19 in association with iron metabolism

(2021) Luc Rochette et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Ferroptosis and Cancer: Complex Relationship and Potential Application of Exosomes

(2021) Shuang Wu et al.   Frontiers in Cell and Developmental Biology

Mitochondrial-derived peptides: New markers for cardiometabolic dysfunction

(2021) Luc Rochette et al.   Archives of Cardiovascular Diseases

Ferroptosis, a novel pharmacological mechanism of anti-cancer drugs

(2020) Yanwei Su et al.   CANCER LETTERS

The biology, function, and biomedical applications of exosomes

(2020) Raghu Kalluri et al.   SCIENCE

Polyunsaturated Fatty Acid Deuteration against Neurodegeneration

(2020) Mikhail S. Shchepinov   TRENDS IN PHARMACOLOGICAL SCIENCES

GDF15 knockdown promotes erastin-induced ferroptosis by decreasing SLC7A11 expression

(2020) Liang Chen et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Loss of Cardiac Ferritin H Facilitates Cardiomyopathy via Slc7a11-Mediated Ferroptosis

(2020) Xuexian Fang et al.   CIRCULATION RESEARCH

Iron chaperone PCBP1 protects murine liver from lipid peroxidation and steatosis

(2020) Olga Protchenko et al.   HEPATOLOGY

Transferrin Receptor Is a Specific Ferroptosis Marker

(2020) Huizhong Feng et al.   Cell Reports

Consensus guidelines for the definition, detection and interpretation of immunogenic cell death

(2020) Lorenzo Galluzzi et al.   Journal for ImmunoTherapy of Cancer

The emerging role of ferroptosis in inflammation

(2020) Yitian Sun et al.   BIOMEDICINE & PHARMACOTHERAPY

Emerging Mechanisms and Disease Relevance of Ferroptosis

(2020) Brent R. Stockwell et al.   TRENDS IN CELL BIOLOGY

Wound healing: cellular mechanisms and pathological outcomes

(2020) Holly N. Wilkinson et al.   Open Biology

Iron Metabolism in Ferroptosis

(2020) Xin Chen et al.   Frontiers in Cell and Developmental Biology

Mitochondrial stress and GDF15 in the pathophysiology of sepsis

(2020) Yasunori Fujita et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

Ferroptosis: molecular mechanisms and health implications

(2020) Daolin Tang et al.   CELL RESEARCH

Insights Into Mechanisms of GDF15 and Receptor GFRAL: Therapeutic Targets

(2020) Luc Rochette et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Regulation of arachidonic acid oxidation and metabolism by lipid electrophiles

(2020) Andrés Trostchansky et al.   PROSTAGLANDINS & OTHER LIPID MEDIATORS

NRF2 plays a critical role in mitigating lipid peroxidation and ferroptosis

(2019) Matthew Dodson et al.   Redox Biology

Ferroptosis is a type of autophagy-dependent cell death

(2019) Borong Zhou et al.   SEMINARS IN CANCER BIOLOGY

Iron supply via NCOA4-mediated ferritin degradation maintains mitochondrial functions

(2019) Motoki Fujimaki et al.   MOLECULAR AND CELLULAR BIOLOGY

CD8+ T cells regulate tumour ferroptosis during cancer immunotherapy

(2019) Weimin Wang et al.   NATURE

Polybrominated Diphenyl Ethers Quinone Induces NCOA4-Mediated Ferritinophagy through Selectively Autophagic Degradation of Ferritin

(2019) Wenjing Dong et al.   CHEMICAL RESEARCH IN TOXICOLOGY

Mitochondria regulation in ferroptosis

(2019) Hai Wang et al.   EUROPEAN JOURNAL OF CELL BIOLOGY

FSP1 is a glutathione-independent ferroptosis suppressor

(2019) Sebastian Doll et al.   NATURE

The CoQ oxidoreductase FSP1 acts parallel to GPX4 to inhibit ferroptosis

(2019) Kirill Bersuker et al.   NATURE

GTP Cyclohydrolase 1/Tetrahydrobiopterin Counteract Ferroptosis through Lipid Remodeling

(2019) Vanessa A. N. Kraft et al.   ACS Central Science

Mini-Review: Oxidative stress, redox stress or redox success ?

(2018) John M.C. Gutteridge et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Redox Functions of Heme Oxygenase-1 and Biliverdin Reductase in Diabetes

(2018) Luc Rochette et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

The Development of the Concept of Ferroptosis

(2018) Tal Hirschhorn et al.   FREE RADICAL BIOLOGY AND MEDICINE

A Dual Role of Heme Oxygenase-1 in Cancer Cells

(2018) Shih-Kai Chiang et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Role of Mitochondria in Ferroptosis

(2018) Minghui Gao et al.   MOLECULAR CELL

Lung tumors with distinct p53 mutations respond similarly to p53 targeted therapy but exhibit genotype-specific statin sensitivity

(2017) Frances K. Turrell et al.   GENES & DEVELOPMENT

Ferritin, cellular iron storage and regulation

(2017) Paolo Arosio et al.   IUBMB LIFE

Role of NOX2-Derived Reactive Oxygen Species in NK Cell–Mediated Control of Murine Melanoma Metastasis

(2017) Ebru Aydin et al.   Cancer Immunology Research

On the Mechanism of Cytoprotection by Ferrostatin-1 and Liproxstatin-1 and the Role of Lipid Peroxidation in Ferroptotic Cell Death

(2017) Omkar Zilka et al.   ACS Central Science

Iron and cancer: recent insights

(2016) David H. Manz et al.   Annals of the New York Academy of Sciences

Autophagy promotes ferroptosis by degradation of ferritin

(2016) Wen Hou et al.   Autophagy

Macrophages and Iron Metabolism

(2016) Miguel P. Soares et al.   IMMUNITY

Can aminothiols be distinguished from reactive oxygen species?

(2016) Luc Rochette et al.   Nature Reviews Cardiology

Loss of cysteinyl-tRNA synthetase (CARS) induces the transsulfuration pathway and inhibits ferroptosis induced by cystine deprivation

(2015) M Hayano et al.   CELL DEATH AND DIFFERENTIATION

Ferroptosis as a p53-mediated activity during tumour suppression

(2015) Le Jiang et al.   NATURE

HSPB1 as a novel regulator of ferroptotic cancer cell death

(2015) X Sun et al.   ONCOGENE

The iron-regulatory hormone hepcidin: A possible therapeutic target?

(2015) Luc Rochette et al.   PHARMACOLOGY & THERAPEUTICS

Anthracyclines/trastuzumab: new aspects of cardiotoxicity and molecular mechanisms

(2015) Luc Rochette et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

Iron, oxidative stress, and redox signaling in the cardiovascular system

(2014) Aurélie Gudjoncik et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Quantitative proteomics identifies NCOA4 as the cargo receptor mediating ferritinophagy

(2014) Joseph D. Mancias et al.   NATURE

Inactivation of the ferroptosis regulator Gpx4 triggers acute renal failure in mice

(2014) Jose Pedro Friedmann Angeli et al.   NATURE CELL BIOLOGY

Lipid Peroxidation: Production, Metabolism, and Signaling Mechanisms of Malondialdehyde and 4-Hydroxy-2-Nonenal

(2014) Antonio Ayala et al.   Oxidative Medicine and Cellular Longevity

The Biology of YAP/TAZ: Hippo Signaling and Beyond

(2014) Stefano Piccolo et al.   PHYSIOLOGICAL REVIEWS

Nitric oxide synthase inhibition and oxidative stress in cardiovascular diseases: Possible therapeutic targets?

(2013) Luc Rochette et al.   PHARMACOLOGY & THERAPEUTICS

Many faces of DAMPs in cancer therapy

(2013) O Krysko et al.   Cell Death & Disease

The role of mitochondria in cellular iron–sulfur protein biogenesis and iron metabolism

(2012) Roland Lill et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Ferroptosis: An Iron-Dependent Form of Nonapoptotic Cell Death

(2012) Scott J. Dixon et al.   CELL

Carbon monoxide: Mechanisms of action and potential clinical implications

(2012) Luc Rochette et al.   PHARMACOLOGY & THERAPEUTICS

Activated human CD4+ T cells express transporters for both cysteine and cystine

(2012) Trine Bøegh Levring et al.   Scientific Reports

Carbon Monoxide Activates Autophagy via Mitochondrial Reactive Oxygen Species Formation

(2011) Seon-Jin Lee et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

General oxidative stress during doxorubicin-induced cardiotoxicity in rats: Absence of cardioprotection and low antioxidant efficiency of alpha-lipoic acid

(2011) Steliana Ghibu et al.   BIOCHIMIE

Programmed Cell Death in Animal Development and Disease

(2011) Yaron Fuchs et al.   CELL

Atrial and Vascular Oxidative Stress in Patients with Heart Failure

(2011) Luc Rochette et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

Free Radical Lipid Peroxidation: Mechanisms and Analysis

(2011) Huiyong Yin et al.   CHEMICAL REVIEWS

Oxidative Stress and Myocardial Gene Alterations Associated with Doxorubicin-Induced Cardiotoxicity in Rats Persist for 2 Months after Treatment Cessation

(2011) C. Richard et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

Generation and Biological Activities of Oxidized Phospholipids

(2009) Valery N. Bochkov et al.   ANTIOXIDANTS & REDOX SIGNALING

Human Biochemistry of the Isoprostane Pathway

(2008) Ginger L. Milne et al.   JOURNAL OF BIOLOGICAL CHEMISTRY