Elevated sphingosine-1-phosphate lyase leads to increased metabolism and reduced survival in adrenocortical carcinoma
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Title
Elevated sphingosine-1-phosphate lyase leads to increased metabolism and reduced survival in adrenocortical carcinoma
Authors
Keywords
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Journal
EUROPEAN JOURNAL OF ENDOCRINOLOGY
Volume 188, Issue 1, Pages -
Publisher
Oxford University Press (OUP)
Online
2023-01-12
DOI
10.1093/ejendo/lvac007
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Note: Only part of the references are listed.- Targeting Sphingolipid Metabolism as a Therapeutic Strategy in Cancer Treatment
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- (2021) Shilpa R. Nagarajan et al. Cancer & Metabolism
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- (2021) Antonia Piazzesi et al. Molecular Oncology
- Identification of novel lipid metabolic biomarkers associated with poor adrenocortical carcinoma prognosis using integrated bioinformatics
- (2021) Chitra Subramanian et al. SURGERY
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- (2021) Feifei Yuan et al. Cell Death & Disease
- S1P signaling, its interactions and cross-talks with other partners and therapeutic importance in colorectal cancer
- (2021) Real Sumayya Abdul Sattar et al. CELLULAR SIGNALLING
- Targeting Sphingolipids for Cancer Therapy
- (2021) Osmel Companioni et al. Frontiers in Oncology
- Reign in the membrane: How common lipids govern mitochondrial function
- (2020) Katsuhiko Funai et al. CURRENT OPINION IN CELL BIOLOGY
- Recent advances in the role of sphingosine 1‐phosphate in cancer
- (2020) Nigel J. Pyne et al. FEBS LETTERS
- Sphingosine-1-phosphate lyase (SGPL1) deficiency is associated with mitochondrial dysfunction
- (2020) A. Maharaj et al. JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY
- Targeted assessment of G0S2 methylation identifies a rapidly recurrent, routinely fatal molecular subtype of adrenocortical carcinoma
- (2019) Dipika R. Mohan et al. CLINICAL CANCER RESEARCH
- Roles of sphingosine-1-phosphate signaling in cancer
- (2019) Peng Wang et al. Cancer Cell International
- Oxidative Phosphorylation as an Emerging Target in Cancer Therapy
- (2018) Thomas M. Ashton et al. CLINICAL CANCER RESEARCH
- An Accurate and Cost-Effective Alternative Method for Measuring Cell Migration with the Circular Wound Closure Assay
- (2018) Michael L De Ieso et al. BIOSCIENCE REPORTS
- Longitudinal patterns of recurrence in patients with adrenocortical carcinoma
- (2018) Jason A. Glenn et al. SURGERY
- Sphingosine-1-phosphate lyase mutations cause primary adrenal insufficiency and steroid-resistant nephrotic syndrome
- (2017) Rathi Prasad et al. JOURNAL OF CLINICAL INVESTIGATION
- Mutations in sphingosine-1-phosphate lyase cause nephrosis with ichthyosis and adrenal insufficiency
- (2017) Svjetlana Lovric et al. JOURNAL OF CLINICAL INVESTIGATION
- Comprehensive Pan-Genomic Characterization of Adrenocortical Carcinoma
- (2016) Siyuan Zheng et al. CANCER CELL
- The Warburg Effect: How Does it Benefit Cancer Cells?
- (2016) Maria V. Liberti et al. TRENDS IN BIOCHEMICAL SCIENCES
- Sphingosine-1-Phosphate Lyase Deficient Cells as a Tool to Study Protein Lipid Interactions
- (2016) Mathias J. Gerl et al. PLoS One
- Aberrant expression of the S1P regulating enzymes, SPHK1 and SGPL1, contributes to a migratory phenotype in OSCC mediated through S1PR2
- (2016) Sathya Narayanan Patmanathan et al. Scientific Reports
- Major Prognostic Role of Ki67 in Localized Adrenocortical Carcinoma After Complete Resection
- (2015) Felix Beuschlein et al. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
- Sphingosine kinase 1 is overexpressed and promotes adrenocortical carcinoma progression
- (2015) Yunze Xu et al. Oncotarget
- CerS2 Haploinsufficiency Inhibits β-Oxidation and Confers Susceptibility to Diet-Induced Steatohepatitis and Insulin Resistance
- (2014) Suryaprakash Raichur et al. Cell Metabolism
- Adrenocortical Carcinoma
- (2014) Tobias Else et al. ENDOCRINE REVIEWS
- Integrated genomic characterization of adrenocortical carcinoma
- (2014) Guillaume Assié et al. NATURE GENETICS
- Adrenocortical carcinoma: A population-based study on incidence and survival in the Netherlands since 1993
- (2013) Thomas M.A. Kerkhofs et al. EUROPEAN JOURNAL OF CANCER
- Ablation of Ceramide Synthase 2 Causes Chronic Oxidative Stress Due to Disruption of the Mitochondrial Respiratory Chain
- (2013) Hila Zigdon et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Genome engineering using the CRISPR-Cas9 system
- (2013) F Ann Ran et al. Nature Protocols
- Diagnostic and prognostic role of steroidogenic factor 1 in adrenocortical carcinoma: a validation study focusing on clinical and pathologic correlates
- (2012) Eleonora Duregon et al. HUMAN PATHOLOGY
- First Evidence of Sphingosine 1-Phosphate Lyase Protein Expression and Activity Downregulation in Human Neoplasm: Implication for Resistance to Therapeutics in Prostate Cancer
- (2012) L. Brizuela et al. MOLECULAR CANCER THERAPEUTICS
- A Phase I Clinical Trial of Safingol in Combination with Cisplatin in Advanced Solid Tumors
- (2011) M. A. Dickson et al. CLINICAL CANCER RESEARCH
- High Diagnostic and Prognostic Value of Steroidogenic Factor-1 Expression in Adrenal Tumors
- (2010) Silviu Sbiera et al. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
- Inhibition of Sphingosine 1-Phosphate Lyase for the Treatment of Rheumatoid Arthritis: Discovery of (E)-1-(4-((1R,2S,3R)-1,2,3,4-Tetrahydroxybutyl)-1H-imidazol-2-yl)ethanone Oxime (LX2931) and (1R,2S,3R)-1-(2-(Isoxazol-3-yl)-1H-imidazol-4-yl)butane-1,2,3,4-tetraol (LX2932)
- (2010) Jeffrey T. Bagdanoff et al. JOURNAL OF MEDICINAL CHEMISTRY
- Disruption of Sphingosine 1-Phosphate Lyase Confers Resistance to Chemotherapy and Promotes Oncogenesis through Bcl-2/Bcl-xL Upregulation
- (2009) S. Colie et al. CANCER RESEARCH
- Gene Expression Profiling Reveals a New Classification of Adrenocortical Tumors and Identifies Molecular Predictors of Malignancy and Survival
- (2009) Aurélien de Reyniès et al. JOURNAL OF CLINICAL ONCOLOGY
- Limited prognostic value of the 2004 International Union Against Cancer staging classification for adrenocortical carcinoma
- (2008) Martin Fassnacht et al. CANCER
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