- Home
- Publications
- Publication Search
- Publication Details
Title
Targeting Sphingolipids for Cancer Therapy
Authors
Keywords
-
Journal
Frontiers in Oncology
Volume 11, Issue -, Pages -
Publisher
Frontiers Media SA
Online
2021-10-21
DOI
10.3389/fonc.2021.745092
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- The Adjuvant of α-Galactosylceramide Presented by Gold Nanoparticles Enhances Antitumor Immune Responses of MUC1 Antigen-Based Tumor Vaccines
- (2021) Yonghui Liu et al. International Journal of Nanomedicine
- Selenium nanoparticles coated with pH responsive silk fibroin complex for fingolimod release and enhanced targeting in thyroid cancer
- (2021) Xiangcai Zou et al. Artificial Cells Nanomedicine and Biotechnology
- Soluble and Exosome-Bound α-Galactosylceramide Mediate Preferential Proliferation of Educated NK Cells with Increased Anti-Tumor Capacity
- (2021) Arnika K. Wagner et al. Cancers
- Liposomal Nanovaccine Containing α-Galactosylceramide and Ganglioside GM3 Stimulates Robust CD8+ T Cell Responses via CD169+ Macrophages and cDC1
- (2021) Joanna Grabowska et al. Vaccines
- Natural killer T cell immunotherapy combined with oncolytic vesicular stomatitis virus or reovirus treatments differentially increases survival in mouse models of ovarian and breast cancer metastasis
- (2021) Simon Gebremeskel et al. Journal for ImmunoTherapy of Cancer
- SphK2/S1P Promotes Metastasis of Triple-Negative Breast Cancer Through the PAK1/LIMK1/Cofilin1 Signaling Pathway
- (2021) Weiwei Shi et al. Frontiers in Molecular Biosciences
- Role of immune regulatory cells in breast cancer: Foe or friend?
- (2021) Huan-Rong Lan et al. INTERNATIONAL IMMUNOPHARMACOLOGY
- Trends in kinase drug discovery: targets, indications and inhibitor design
- (2021) Misty M. Attwood et al. NATURE REVIEWS DRUG DISCOVERY
- Synergism of 4HPR and SAHA increases anti-tumor actions in glioblastoma cells
- (2020) Firas Khathayer et al. APOPTOSIS
- Sphingosine kinase‐2 is overexpressed in large granular lymphocyte leukaemia and promotes survival through Mcl‐1
- (2020) Francis R. LeBlanc et al. BRITISH JOURNAL OF HAEMATOLOGY
- Nanoparticles carrying fingolimod and methotrexate enables targeted induction of apoptosis and immobilization of invasive thyroid cancer
- (2020) E. Niemelä et al. EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS
- Activation of Invariant Natural Killer T Cell Subsets in C57BL/6J Mice by Different Injection Modes of α-galactosylceramide
- (2020) Ming Meng et al. Iranian Journal of Allergy Asthma and Immunology
- Impaired lipid biosynthesis hinders anti-tumor efficacy of intratumoral iNKT cells
- (2020) Sicheng Fu et al. Nature Communications
- Vaccines adjuvanted with an NKT cell agonist induce effective T-cell responses in models of CNS lymphoma
- (2020) Carole Grasso et al. Immunotherapy
- Sorafenib Treatment and Modulation of the Sphingolipid Pathway Affect Proliferation and Viability of Hepatocellular Carcinoma In Vitro
- (2020) Katja Jakobi et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Mixed micelles of TPGS and Soluplus® for co-delivery of paclitaxel and fenretinide: in vitro and in vivo anticancer study
- (2020) Yutong Wang et al. PHARMACEUTICAL DEVELOPMENT AND TECHNOLOGY
- Fenretinide-polyethylene glycol (PEG) conjugate with improved solubility enhanced cytotoxicity to cancer cell and potent in vivo efficacy
- (2020) Yutong Wang et al. PHARMACEUTICAL DEVELOPMENT AND TECHNOLOGY
- Lipo-Based Vaccines as an Approach to Target Dendritic Cells for Induction of T- and iNKT Cell Responses
- (2020) Dorian A. Stolk et al. Frontiers in Immunology
- Phase II study of α-galactosylceramide-pulsed antigen-presenting cells in patients with advanced or recurrent non-small cell lung cancer
- (2020) Takahide Toyoda et al. Journal for ImmunoTherapy of Cancer
- A phase I study of loco-regional immunotherapy by transbronchial injection of α-galactosylceramide-pulsed antigen presenting cells in patients with lung cancer
- (2020) Fumihiro Ishibashi et al. CLINICAL IMMUNOLOGY
- Microencapsulation of amorphous solid dispersions of fenretinide enhances drug solubility and release from PLGA in vitro and in vivo
- (2020) Kari Nieto et al. INTERNATIONAL JOURNAL OF PHARMACEUTICS
- Targeting SphK2 Reverses Acquired Resistance of Regorafenib in Hepatocellular Carcinoma
- (2020) Weiwei Shi et al. Frontiers in Oncology
- Nanomicellar Lenalidomide–Fenretinide Combination Suppresses Tumor Growth in an MYCN Amplified Neuroblastoma Tumor
- (2020) Isabella Orienti et al. International Journal of Nanomedicine
- Inhibition of Lysosomal Function Mitigates Protective Mitophagy and Augments Ceramide Nanoliposome-Induced Cell Death in Head and Neck Squamous Cell Carcinoma
- (2020) Jeremy JP Shaw et al. MOLECULAR CANCER THERAPEUTICS
- Natural Killer T-Cell Agonist α-Galactosylceramide and PD-1 Blockade Synergize to Reduce Tumor Development in a Preclinical Model of Colon Cancer
- (2020) Ying Wang et al. Frontiers in Immunology
- Therapeutic potential of Fingolimod in triple negative breast cancer preclinical models
- (2020) Tristan Rupp et al. Translational Oncology
- Pivotal role of mitophagy in response of acute myelogenous leukemia to a ceramide-tamoxifen-containing drug regimen
- (2019) Samy A.F. Morad et al. EXPERIMENTAL CELL RESEARCH
- Fingolimod sensitizes EGFR wild‑type non‑small cell lung cancer cells to lapatinib or sorafenib and induces cell cycle arrest
- (2019) Kohki Ota et al. ONCOLOGY REPORTS
- Sphingosine-kinase-1 signaling promotes metastasis of triple-negative breast cancer
- (2019) Sunil Acharya et al. CANCER RESEARCH
- Combination of fenretinide and ABT-263 induces apoptosis through NOXA for head and neck squamous cell carcinoma treatment
- (2019) Erin L. Britt et al. PLoS One
- Sphingosine kinase 2 inhibitor ABC294640 displays anti-epithelial ovarian cancer activities in vitro and in vivo
- (2019) Keqi Song et al. OncoTargets and Therapy
- A new bioavailable fenretinide formulation with antiproliferative, antimetabolic, and cytotoxic effects on solid tumors
- (2019) Isabella Orienti et al. Cell Death & Disease
- A novel oral micellar fenretinide formulation with enhanced bioavailability and antitumour activity against multiple tumours from cancer stem cells
- (2019) Isabella Orienti et al. JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH
- Fenretinide, Tocilizumab & Reparixin Provide Multifaceted Disruption of Oral Squamous Cell Carcinoma Stem Cell Properties: Implications for Tertiary chemoprevention.
- (2019) Susan R. Mallery et al. MOLECULAR CANCER THERAPEUTICS
- Fenretinide via NOXA induction, enhanced activity of the BCL-2 inhibitor venetoclax in high BCL-2-expressing neuroblastoma preclinical models
- (2019) Thinh H. Nguyen et al. MOLECULAR CANCER THERAPEUTICS
- A Novel Nanomicellar Combination of Fenretinide and Lenalidomide Shows Marked Antitumor Activity in a Neuroblastoma Xenograft Model
- (2019) Isabella Orienti et al. Drug Design Development and Therapy
- Targeting sphingosine kinase 2 by ABC294640 inhibits human skin squamous cell carcinoma cell growth
- (2018) Jianbo Zhou et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Targeting the SphK1/S1P/S1PR1 Axis That Links Obesity, Chronic Inflammation, and Breast Cancer Metastasis
- (2018) Masayuki Nagahashi et al. CANCER RESEARCH
- Nanoliposome C6-Ceramide Increases the Anti-tumor Immune Response and Slows Growth of Liver Tumors in Mice
- (2018) Guangfu Li et al. GASTROENTEROLOGY
- The sphingosine kinase 2 inhibitor ABC294640 displays anti-non-small cell lung cancer activities in vitro and in vivo
- (2018) Lu Dai et al. INTERNATIONAL JOURNAL OF CANCER
- Spontaneous regression of tumor-stage cutaneous T-cell lymphoma in a multiple sclerosis patient after discontinuing fingolimod
- (2018) Anne Froehlich et al. Multiple Sclerosis Journal
- Fenretinide inhibits the proliferation and migration of human liver cancer HepG2 cells by downregulating the activation of myosin light chain kinase through the p38‑MAPK signaling pathway
- (2018) Ling Zhang et al. ONCOLOGY REPORTS
- Fingolimod interrupts the cross talk between estrogen metabolism and sphingolipid metabolism within prostate cancer cells
- (2018) Rasha M. Allam et al. TOXICOLOGY LETTERS
- Targeting S1PR1/STAT3 loop abrogates desmoplasia and chemosensitizes pancreatic cancer to gemcitabine
- (2018) Manendra Babu Lankadasari et al. Theranostics
- Spontaneous regression of tumor-stage cutaneous T-cell lymphoma in a multiple sclerosis patient after discontinuing fingolimod
- (2018) Anne Froehlich et al. Multiple Sclerosis Journal
- The combination of a sphingosine kinase 2 inhibitor (ABC294640) and a Bcl-2 inhibitor (ABT-199) displays synergistic anti-myeloma effects in myeloma cells without a t(11;14) translocation
- (2018) Pasupathi Sundaramoorthy et al. Cancer Medicine
- FTY720 enhances the anti-tumor activity of carboplatin and tamoxifen in a patient-derived xenograft model of ovarian cancer
- (2018) Kelly M. Kreitzburg et al. CANCER LETTERS
- Fenretinide targeting of human colon cancer sphere cells through cell cycle regulation and stress‑responsive activities
- (2018) Lanlan Liu et al. Oncology Letters
- Fingolimod augments Pemetrexed killing of non-small cell lung cancer and overcomes resistance to ERBB inhibition
- (2018) Laurence Booth et al. CANCER BIOLOGY & THERAPY
- TRIM14 promotes colorectal cancer cell migration and invasion through the SPHK1/STAT3 pathway
- (2018) Zhonghai Jin et al. Cancer Cell International
- Quality of Life in a Randomized Breast Cancer Prevention Trial of Low-Dose Tamoxifen and Fenretinide in Premenopausal Women
- (2018) Davide Serrano et al. Cancer Prevention Research
- Pharmacological inhibition of serine palmitoyl transferase and sphingosine kinase-1/-2 inhibits Merkel Cell Carcinoma cell proliferation
- (2018) Vishwanath Kumble Bhat et al. JOURNAL OF INVESTIGATIVE DERMATOLOGY
- PP2A deactivation is a common event in oral cancer and reactivation by FTY720 shows promising therapeutic potential
- (2017) Bharath K. Velmurugan et al. JOURNAL OF CELLULAR PHYSIOLOGY
- Doxorubicin effect is enhanced by sphingosine-1-phosphate signaling antagonist in breast cancer
- (2017) Eriko Katsuta et al. JOURNAL OF SURGICAL RESEARCH
- Ceramide Nanoliposomes as a MLKL-Dependent, Necroptosis-Inducing, Chemotherapeutic Reagent in Ovarian Cancer
- (2017) Xuewei Zhang et al. MOLECULAR CANCER THERAPEUTICS
- ABC294640, A Novel Sphingosine Kinase 2 Inhibitor, Induces Oncogenic Virus–Infected Cell Autophagic Death and Represses Tumor Growth
- (2017) Lu Dai et al. MOLECULAR CANCER THERAPEUTICS
- Combination treatment of FTY720 and cisplatin exhibits enhanced antitumour effects on cisplatin-resistant non-small lung cancer cells
- (2017) Yang Li et al. ONCOLOGY REPORTS
- Targeting the S1P/S1PR1 axis mitigates cancer-induced bone pain and neuroinflammation
- (2017) Shaness A. Grenald et al. PAIN
- A randomized phase II study to assess the effect of adjuvant immunotherapy using α-GalCer-pulsed dendritic cells in the patients with completely resected stage II–IIIA non-small cell lung cancer: study protocol for a randomized controlled trial
- (2017) Hideo Saka et al. Trials
- The sphingosine kinase 2 inhibitor ABC294640 inhibits cervical carcinoma cell growth
- (2017) Ling Xu et al. Oncotarget
- Core shell lipid-polymer hybrid nanoparticles with combined docetaxel and molecular targeted therapy for the treatment of metastatic prostate cancer
- (2017) Qi Wang et al. Scientific Reports
- Inhibition of ceramide glucosylation sensitizes lung cancer cells to ABC294640, a first-in-class small molecule SphK2 inhibitor
- (2016) Shuhong Guan et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- SphK1 inhibitor potentiates the anti-cancer effect of EGCG on leukaemia cells
- (2016) Shuntaro Tsukamoto et al. BRITISH JOURNAL OF HAEMATOLOGY
- A phase 2 study of the sphingosine-1-phosphate antibody sonepcizumab in patients with metastatic renal cell carcinoma
- (2016) Sumanta K. Pal et al. CANCER
- Prognostic Significance of VEGF after Twenty-Year Follow-up in a Randomized Trial of Fenretinide in Non-Muscle-Invasive Bladder Cancer
- (2016) M. Puntoni et al. Cancer Prevention Research
- Sphingosine-1-phosphate-activated TRPC1 channel controls chemotaxis of glioblastoma cells
- (2016) Sophie Lepannetier et al. CELL CALCIUM
- FTY720 (Fingolimod) attenuates basal and sphingosine-1-phosphate-evoked thyroid cancer cell invasion
- (2016) Veronica Kalhori et al. ENDOCRINE-RELATED CANCER
- Fingolimod targeting protein phosphatase 2A differently affects IL-33 induced IL-2 and IFN-γ production in CD8+ lymphocytes
- (2016) Florian Ottenlinger et al. EUROPEAN JOURNAL OF IMMUNOLOGY
- SphK1 inhibitor SKI II inhibits the proliferation of human hepatoma HepG2 cells via the Wnt5A/β-catenin signaling pathway
- (2016) Hong Liu et al. LIFE SCIENCES
- FTY720-induced enhancement of autophagy protects cells from FTY720 cytotoxicity in colorectal cancer
- (2016) JUAN LI et al. ONCOLOGY REPORTS
- Suppression of c-Myc and RRM2 expression in pancreatic cancer cells by the sphingosine kinase-2 inhibitor ABC294640
- (2016) Clayton S. Lewis et al. Oncotarget
- Proteasomal degradation of sphingosine kinase 1 and inhibition of dihydroceramide desaturase by the sphingosine kinase inhibitors, SKi or ABC294640, induces growth arrest in androgen-independent LNCaP-AI prostate cancer cells
- (2016) Melissa McNaughton et al. Oncotarget
- Antitumor effect of the novel sphingosine kinase 2 inhibitor ABC294640 is enhanced by inhibition of autophagy and by sorafenib in human cholangiocarcinoma cells
- (2016) Xiwei Ding et al. Oncotarget
- Liposomal C6 Ceramide Activates Protein Phosphatase 1 to Inhibit Melanoma Cells
- (2016) Fangzhen Jiang et al. PLoS One
- Fenretinide (4-HPR) Targets Caspase-9, ERK 1/2 and the Wnt3a/β-Catenin Pathway in Medulloblastoma Cells and Medulloblastoma Cell Spheroids
- (2016) Barbara Bassani et al. PLoS One
- A Sphingosine Kinase-1 Inhibitor, SKI-II, Induces Growth Inhibition and Apoptosis in Human Gastric Cancer Cells
- (2015) Pei-Hua Li et al. Asian Pacific Journal of Cancer Prevention
- SphK1 inhibitor II (SKI-II) inhibits acute myelogenous leukemia cell growth in vitro and in vivo
- (2015) Li Yang et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Regulation of cellular sphingosine-1-phosphate by sphingosine kinase 1 and sphingosine-1-phopshate lyase determines chemotherapy resistance in gastroesophageal cancer
- (2015) Kasia Matula et al. BMC CANCER
- ABC294640, a sphingosine kinase 2 inhibitor, enhances the antitumor effects of TRAIL in non-small cell lung cancer
- (2015) Jie Yang et al. CANCER BIOLOGY & THERAPY
- Sphingosine kinase inhibitors decrease viability and induce cell death in natural killer-large granular lymphocyte leukemia
- (2015) Francis R LeBlanc et al. CANCER BIOLOGY & THERAPY
- Lysosomal Degradation of CD44 Mediates Ceramide Nanoliposome-induced Anoikis and Diminished Extravasation in Metastatic Carcinoma Cells
- (2015) Jeremy K. Haakenson et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Targeting sphingosine kinase 2 (SphK2) by ABC294640 inhibits colorectal cancer cell growth in vitro and in vivo
- (2015) Cai Xun et al. JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH
- Dynamics of ceramide generation and metabolism in response to fenretinide – Diversity within and among leukemia
- (2015) Samy A.F. Morad et al. LEUKEMIA RESEARCH
- Downregulation of Critical Oncogenes by the Selective SK2 Inhibitor ABC294640 Hinders Prostate Cancer Progression
- (2015) R. S. Schrecengost et al. MOLECULAR CANCER RESEARCH
- The Sphingosine Kinase 2 Inhibitor ABC294640 Reduces the Growth of Prostate Cancer Cells and Results in Accumulation of Dihydroceramides In Vitro and In Vivo
- (2015) H. Venant et al. MOLECULAR CANCER THERAPEUTICS
- Sphingosine Kinase-1 Protects Multiple Myeloma from Apoptosis Driven by Cancer-Specific Inhibition of RTKs
- (2015) S. Tsukamoto et al. MOLECULAR CANCER THERAPEUTICS
- Co-delivery of doxorubicin and PEGylated C16-ceramide by nanoliposomes for enhanced therapy against multidrug resistance
- (2015) Xiao Su et al. Nanomedicine
- FTY720 enhances TRAIL-mediated apoptosis by up-regulating DR5 and down-regulating Mcl-1 in cancer cells
- (2015) Seon Min Woo et al. Oncotarget
- Sphingosine kinase 1 is a reliable prognostic factor and a novel therapeutic target for uterine cervical cancer
- (2015) Hyun-Soo Kim et al. Oncotarget
- C6-ceramide nanoliposome suppresses tumor metastasis by eliciting PI3K and PKCζ tumor-suppressive activities and regulating integrin affinity modulation
- (2015) Pu Zhang et al. Scientific Reports
- The phosphorylated prodrug FTY720 is a histone deacetylase inhibitor that reactivates ERα expression and enhances hormonal therapy for breast cancer
- (2015) N C Hait et al. Oncogenesis
- The mechanisms of Fenretinide-mediated anti-cancer activity and prevention of obesity and type-2 diabetes
- (2014) Nimesh Mody et al. BIOCHEMICAL PHARMACOLOGY
- Evolving concepts in cancer therapy through targeting sphingolipid metabolism
- (2014) Jean-Philip Truman et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS
- Inhibition of sphingosine kinase 2 downregulates the expression of c-Myc and Mcl-1 and induces apoptosis in multiple myeloma
- (2014) J. Kummetha Venkata et al. BLOOD
- Sphingosine analog fingolimod (FTY720) increases radiation sensitivity of human breast cancer cells in vitro
- (2014) Giulia Marvaso et al. CANCER BIOLOGY & THERAPY
- Fingolimod: A Review of Its Use in Relapsing-Remitting Multiple Sclerosis
- (2014) Mark Sanford DRUGS
- Involvement of Hydrogen Peroxide in Safingol-Induced Endonuclease G-Mediated Apoptosis of Squamous Cell Carcinoma Cells
- (2014) Masakazu Hamada et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- TRPM7 regulates proliferation and polarisation of macrophages
- (2014) T. Schilling et al. JOURNAL OF CELL SCIENCE
- FTY720 enhances chemosensitivity of colon cancer cells to doxorubicin and etoposide via the modulation of P-glycoprotein and multidrug resistance protein 1
- (2014) Ying Xing et al. Journal of Digestive Diseases
- FTY720 impairs CD8 T-cell function independently of the sphingosine-1-phosphate pathway
- (2014) Achilles Ntranos et al. JOURNAL OF NEUROIMMUNOLOGY
- PP2A Inhibition Is a Common Event in Colorectal Cancer and Its Restoration Using FTY720 Shows Promising Therapeutic Potential
- (2014) I. Cristobal et al. MOLECULAR CANCER THERAPEUTICS
- Inhibition of sphingosine kinase-2 ablates androgen resistant prostate cancer proliferation and survival
- (2014) Matthew M. Gestaut et al. Pharmacological Reports
- A sphingosine kinase inhibitor combined with temozolomide induces glioblastoma cell death through accumulation of dihydrosphingosine and dihydroceramide, endoplasmic reticulum stress and autophagy
- (2014) J Noack et al. Cell Death & Disease
- SKI-II reverses the chemoresistance of SGC7901/DDP gastric cancer cells
- (2014) YING LIU et al. Oncology Letters
- S1PR1 Is Crucial for Accumulation of Regulatory T Cells in Tumors via STAT3
- (2014) Saul J. Priceman et al. Cell Reports
- Fenretinide Targets Chronic Myeloid Leukemia Stem/Progenitor Cells by Regulation of Redox Signaling
- (2013) Yanzhi Du et al. ANTIOXIDANTS & REDOX SIGNALING
- The blockage of Ras/ERK pathway augments the sensitivity of SphK1 inhibitor SKI II in human hepatoma HepG2 cells
- (2013) Caixia Zhang et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Tamoxifen magnifies therapeutic impact of ceramide in human colorectal cancer cells independent of p53
- (2013) Samy A.F. Morad et al. BIOCHEMICAL PHARMACOLOGY
- Circulating hormones and breast cancer risk in premenopausal women: a randomized trial of low-dose tamoxifen and fenretinide
- (2013) Harriet Johansson et al. BREAST CANCER RESEARCH AND TREATMENT
- Synergistic combination therapy with nanoliposomal C6-ceramide and vinblastine is associated with autophagy dysfunction in hepatocarcinoma and colorectal cancer models
- (2013) Pavan P. Adiseshaiah et al. CANCER LETTERS
- Combination of FTY720 with cisplatin exhibits antagonistic effects in ovarian cancer cells: Role of autophagy
- (2013) NING ZHANG et al. INTERNATIONAL JOURNAL OF ONCOLOGY
- Targeting Sphingosine Kinase Induces Apoptosis and Tumor Regression for KSHV-Associated Primary Effusion Lymphoma
- (2013) Z. Qin et al. MOLECULAR CANCER THERAPEUTICS
- Inhibition of Insulin-like Growth Factor-Binding Protein-3 Signaling through Sphingosine Kinase-1 Sensitizes Triple-Negative Breast Cancer Cells to EGF Receptor Blockade
- (2013) J. L. Martin et al. MOLECULAR CANCER THERAPEUTICS
- Liposomal codelivery of a synergistic combination of bioactive lipids in the treatment of acute myeloid leukemia
- (2013) Kuan-Boone Tan et al. Nanomedicine
- Phase I trial of fenretinide delivered orally in a novel organized lipid complex in patients with relapsed/refractory neuroblastoma: A report from the new approaches to neuroblastoma therapy (NANT) consortium
- (2013) Barry J. Maurer et al. PEDIATRIC BLOOD & CANCER
- Inhibition of Ceramide Metabolism Sensitizes Human Leukemia Cells to Inhibition of BCL2-Like Proteins
- (2013) Lavona Casson et al. PLoS One
- C6-Ceramide Nanoliposomes Target the Warburg Effect in Chronic Lymphocytic Leukemia
- (2013) Lindsay K. Ryland et al. PLoS One
- Preferential eradication of acute myelogenous leukemia stem cells by fenretinide
- (2013) H. Zhang et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Ovarian and Breast Cancer Spheres Are Similar in Transcriptomic Features and Sensitive to Fenretinide
- (2013) Haiwei Wang et al. Biomed Research International
- Clinical regressions and broad immune activation following combination therapy targeting human NKT cells in myeloma
- (2012) J. Richter et al. BLOOD
- Fingolimod blocks immunosurveillance of myeloma and B-cell lymphoma resulting in cancer development in mice
- (2012) K. B. Lorvik et al. BLOOD
- Increased apoptosis in cancer cells in vitro and in vivo by ceramides in transferrin-modified liposomes
- (2012) Alexander Koshkaryev et al. CANCER BIOLOGY & THERAPY
- S1PR1-STAT3 Signaling Is Crucial for Myeloid Cell Colonization at Future Metastatic Sites
- (2012) Jiehui Deng et al. CANCER CELL
- Sphingosine kinase-1 inhibition sensitizes curcumin-induced growth inhibition and apoptosis in ovarian cancer cells
- (2012) Yan-li Yang et al. CANCER SCIENCE
- Sphingosine Kinase 1 Overexpression Contributes to Cetuximab Resistance in Human Colorectal Cancer Models
- (2012) R. Rosa et al. CLINICAL CANCER RESEARCH
- Sphingosine kinase isoforms as a therapeutic target in endocrine therapy resistant luminal and basal-A breast cancer
- (2012) James W Antoon et al. EXPERIMENTAL BIOLOGY AND MEDICINE
- Accumulation of Activated Invariant Natural Killer T Cells in the Tumor Microenvironment after α-Galactosylceramide-Pulsed Antigen Presenting Cells
- (2012) Kaoru Nagato et al. JOURNAL OF CLINICAL IMMUNOLOGY
- Targeting glucosylceramide synthase synergizes with C6-ceramide nanoliposomes to induce apoptosis in natural killer cell leukemia
- (2012) Rebecca J. Watters et al. LEUKEMIA & LYMPHOMA
- Ceramide-Antiestrogen Nanoliposomal Combinations--Novel Impact of Hormonal Therapy in Hormone-Insensitive Breast Cancer
- (2012) S. A. F. Morad et al. MOLECULAR CANCER THERAPEUTICS
- Dual inhibition of sphingosine kinase isoforms ablates TNF-induced drug resistance
- (2012) Barbara Beckman ONCOLOGY REPORTS
- Fingolimod potentiates the effects of sunitinib malate in a rat breast cancer model
- (2011) Yoanne Mousseau et al. BREAST CANCER RESEARCH AND TREATMENT
- Targeting NFĸB mediated breast cancer chemoresistance through selective inhibition of sphingosine kinase-2
- (2011) James W. Antoon et al. CANCER BIOLOGY & THERAPY
- Combinatorial therapies improve the therapeutic efficacy of nanoliposomal ceramide for pancreatic cancer
- (2011) Yixing Jiang et al. CANCER BIOLOGY & THERAPY
- A Phase I Clinical Trial of Safingol in Combination with Cisplatin in Advanced Solid Tumors
- (2011) M. A. Dickson et al. CLINICAL CANCER RESEARCH
- Comparison of Clinical and Immunological Effects of Intravenous and Intradermal Administration of -GalactosylCeramide (KRN7000)-Pulsed Dendritic Cells
- (2011) A. J. Nicol et al. CLINICAL CANCER RESEARCH
- Identification of Dihydroceramide Desaturase as a Directin VitroTarget for Fenretinide
- (2011) Mehrdad Rahmaniyan et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Prognostic Effect of Circulating Adiponectin in a Randomized 2 × 2 Trial of Low-Dose Tamoxifen and Fenretinide in Premenopausal Women at Risk for Breast Cancer
- (2011) Debora Macis et al. JOURNAL OF CLINICAL ONCOLOGY
- In vivo efficacy of a novel liposomal formulation of safingol in the treatment of acute myeloid leukemia
- (2011) Kuan-Boone Tan et al. JOURNAL OF CONTROLLED RELEASE
- Pharmacological inhibition of sphingosine kinase isoforms alters estrogen receptor signaling in human breast cancer
- (2011) J. W. Antoon et al. JOURNAL OF MOLECULAR ENDOCRINOLOGY
- Evaluation of Cell Cycle Arrest in Estrogen Responsive MCF-7 Breast Cancer Cells: Pitfalls of the MTS Assay
- (2011) Eileen M. McGowan et al. PLoS One
- The role of reactive oxygen species and autophagy in safingol-induced cell death
- (2011) L-U Ling et al. Cell Death & Disease
- Role of reactive oxygen species in the synergistic cytotoxicity of safingol-based combination regimens with conventional chemotherapeutics
- (2011) Gigi Chiu Oncology Letters
- Bioconjugation of Calcium Phosphosilicate Composite Nanoparticles for Selective Targeting of Human Breast and Pancreatic Cancers In Vivo
- (2010) Brian M. Barth et al. ACS Nano
- FTY720 induces necrotic cell death and autophagy in ovarian cancer cells: A protective role of autophagy
- (2010) Ning Zhang et al. Autophagy
- Targeting of survivin by nanoliposomal ceramide induces complete remission in a rat model of NK-LGL leukemia
- (2010) X. Liu et al. BLOOD
- A phase II study of fenretinide in patients with hormone refractory prostate cancer: a trial of the Cancer Therapeutics Research Group
- (2010) M. M. Moore et al. CANCER CHEMOTHERAPY AND PHARMACOLOGY
- Migration and immunological reaction after the administration of αGalCer-pulsed antigen-presenting cells into the submucosa of patients with head and neck cancer
- (2010) Motoyoshi Kurosaki et al. CANCER IMMUNOLOGY IMMUNOTHERAPY
- FTY720 (Fingolimod) Sensitizes Prostate Cancer Cells to Radiotherapy by Inhibition of Sphingosine Kinase-1
- (2010) D. Pchejetski et al. CANCER RESEARCH
- Suppression of colitis-driven colon cancer in mice by a novel small molecule inhibitor of sphingosine kinase
- (2010) Alexander A. Chumanevich et al. CARCINOGENESIS
- FTY720 and (S)-FTY720 vinylphosphonate inhibit sphingosine kinase 1 and promote its proteasomal degradation in human pulmonary artery smooth muscle, breast cancer and androgen-independent prostate cancer cells
- (2010) Francesca Tonelli et al. CELLULAR SIGNALLING
- Induction of NKT cell-specific immune responses in cancer tissues after NKT cell-targeted adoptive immunotherapy
- (2010) Kazuki Yamasaki et al. CLINICAL IMMUNOLOGY
- Antiestrogenic Effects of the Novel Sphingosine Kinase-2 Inhibitor ABC294640
- (2010) James W. Antoon et al. ENDOCRINOLOGY
- Increased radiation sensitivity of head and neck squamous cell carcinoma with sphingosine kinase 1 inhibition
- (2010) Uttam K. Sinha et al. HEAD AND NECK-JOURNAL FOR THE SCIENCES AND SPECIALTIES OF THE HEAD AND NECK
- PTEN- and p53-mediated apoptosis and cell cycle arrest by FTY720 in gastric cancer cells and nude mice
- (2010) Tongsen Zheng et al. JOURNAL OF CELLULAR BIOCHEMISTRY
- Pharmacology and Antitumor Activity of ABC294640, a Selective Inhibitor of Sphingosine Kinase-2
- (2010) K. J. French et al. JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS
- Phase III double-blind, placebo-controlled, prospective randomized trial of adjuvant tamoxifen vs. tamoxifen and fenretinide in postmenopausal women with positive receptors (EB193): an intergroup trial coordinated by the Eastern Cooperative Oncology Group
- (2010) Ruta D. Rao et al. MEDICAL ONCOLOGY
- iNKT Cells Control Mouse Spontaneous Carcinoma Independently of Tumor-Specific Cytotoxic T Cells
- (2010) Matteo Bellone et al. PLoS One
- Sphingosine-1-phosphate and immune regulation: trafficking and beyond
- (2010) Hongbo Chi TRENDS IN PHARMACOLOGICAL SCIENCES
- Induction of apoptosis of detached oral squamous cell carcinoma cells by safingol. Possible role of Bim, focal adhesion kinase and endonuclease G
- (2009) Takayuki Noda et al. APOPTOSIS
- Safingol (l-threo-sphinganine) induces autophagy in solid tumor cells through inhibition of PKC and the PI3-kinase pathway
- (2009) Jesse Coward et al. Autophagy
- Combination therapy ofin vitro-expanded natural killer T cells and α-galactosylceramide-pulsed antigen-presenting cells in patients with recurrent head and neck carcinoma
- (2009) Naoki Kunii et al. CANCER SCIENCE
- Suppression of Androgen-Independent Prostate Cancer Cell Aggressiveness by FTY720: Validating Runx2 as a Potential Antimetastatic Drug Screening Platform
- (2009) C.-W. Chua et al. CLINICAL CANCER RESEARCH
- Oral Fenretinide in Biochemically Recurrent Prostate Cancer: A California Cancer Consortium Phase II Trial
- (2009) Eric Cheung et al. Clinical Genitourinary Cancer
- The role of protein kinase C in the synergistic interaction of safingol and irinotecan in colon cancer cells
- (2009) Chiu INTERNATIONAL JOURNAL OF ONCOLOGY
- Phase II trial of fenretinide (NSC 374551) in patients with recurrent small cell lung cancer
- (2009) Bryan J. Schneider et al. INVESTIGATIONAL NEW DRUGS
- Randomized Double-Blind 2 × 2 Trial of Low-Dose Tamoxifen and Fenretinide for Breast Cancer Prevention in High-Risk Premenopausal Women
- (2009) Andrea Decensi et al. JOURNAL OF CLINICAL ONCOLOGY
- A Phase I-II Study of -Galactosylceramide-Pulsed IL-2/GM-CSF-Cultured Peripheral Blood Mononuclear Cells in Patients with Advanced and Recurrent Non-Small Cell Lung Cancer
- (2009) S. Motohashi et al. JOURNAL OF IMMUNOLOGY
- Nanoliposomal Short-Chain Ceramide Inhibits Agonist-Dependent Translocation of Neurotensin Receptor 1 to Structured Membrane Microdomains in Breast Cancer Cells
- (2009) Y. Heakal et al. MOLECULAR CANCER RESEARCH
- Effects of Phosphorylation of Immunomodulatory Agent FTY720 (Fingolimod) on Antiproliferative Activity against Breast and Colon Cancer Cells
- (2008) Yasuo Nagaoka et al. BIOLOGICAL & PHARMACEUTICAL BULLETIN
- Effect of Fenretinide and Low-Dose Tamoxifen on Insulin Sensitivity in Premenopausal Women at High Risk for Breast Cancer
- (2008) H. Johansson et al. CANCER RESEARCH
- Combining Nanoliposomal Ceramide with Sorafenib Synergistically Inhibits Melanoma and Breast Cancer Cell Survival to Decrease Tumor Development
- (2008) M. A. Tran et al. CLINICAL CANCER RESEARCH
- Phase III Prevention Trial of Fenretinide in Patients with Resected Non Muscle-Invasive Bladder Cancer
- (2008) A. L. Sabichi et al. CLINICAL CANCER RESEARCH
- Principles of bioactive lipid signalling: lessons from sphingolipids
- (2008) Yusuf A. Hannun et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Antiproliferative and Overadditive Effects of Rapamycin and FTY720 in Pancreatic Cancer Cells In Vitro
- (2008) Y. Shen et al. TRANSPLANTATION PROCEEDINGS
Publish scientific posters with Peeref
Peeref publishes scientific posters from all research disciplines. Our Diamond Open Access policy means free access to content and no publication fees for authors.
Learn MoreAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started