- Home
- Publications
- Publication Search
- Publication Details
Title
Aged lipid‐laden microglia display impaired responses to stroke
Authors
Keywords
-
Journal
EMBO Molecular Medicine
Volume -, Issue -, Pages -
Publisher
EMBO
Online
2022-12-21
DOI
10.15252/emmm.202217175
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Absent in Melanoma 2 (AIM2) Regulates the Stability of Regulatory T Cells
- (2022) Beatriz Lozano-Ruiz et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Stroke induces disease-specific myeloid cells in the brain parenchyma and pia
- (2022) Carolin Beuker et al. Nature Communications
- Microglia-Secreted Factors Enhance Dopaminergic Differentiation of Tissue- and iPSC-Derived Human Neural Stem Cells
- (2021) Sissel Ida Schmidt et al. Stem Cell Reports
- White matter aging drives microglial diversity
- (2021) Shima Safaiyan et al. NEURON
- Intracellular lipid droplet accumulation occurs early following viral infection and is required for an efficient interferon response
- (2021) E. A. Monson et al. Nature Communications
- Context‐dependent transcriptional regulation of microglial proliferation
- (2021) Sarah Belhocine et al. GLIA
- Repeated Administration of 2-Hydroxypropyl-β-Cyclodextrin (HPβCD) Attenuates the Chronic Inflammatory Response to Experimental Stroke
- (2021) Danielle A. Becktel et al. JOURNAL OF NEUROSCIENCE
- Lipid-droplet-accumulating microglia represent a dysfunctional and proinflammatory state in the aging brain
- (2020) Julia Marschallinger et al. NATURE NEUROSCIENCE
- Repopulating Microglia Promote Brain Repair in an IL-6-Dependent Manner
- (2020) Emily F. Willis et al. CELL
- Investigating Microglia in Health and Disease: Challenges and Opportunities
- (2020) Veronique E. Miron et al. TRENDS IN IMMUNOLOGY
- Decoding the Transcriptional Response to Ischemic Stroke in Young and Aged Mouse Brain
- (2020) Peter Androvic et al. Cell Reports
- Differential accumulation of storage bodies with aging defines discrete subsets of microglia in the healthy brain
- (2020) Jeremy Carlos Burns et al. eLife
- Regulation of lipid metabolism in pancreatic beta cells by interferon gamma: A link to anti-viral function
- (2020) Nguyen T.T. Truong et al. CYTOKINE
- CSF1R inhibition by a small-molecule inhibitor is not microglia specific; affecting hematopoiesis and the function of macrophages
- (2020) Fengyang Lei et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Dendritic Cells and Microglia Have Non-redundant Functions in the Inflamed Brain with Protective Effects of Type 1 cDCs
- (2020) Mattia Gallizioli et al. Cell Reports
- Shaping Neuronal Fate: Functional Heterogeneity of Direct Microglia-Neuron Interactions
- (2020) Csaba Cserép et al. NEURON
- Microglia depletion increase brain injury after acute ischemic stroke in aged mice
- (2020) Shirley Marino Lee et al. EXPERIMENTAL NEUROLOGY
- Spatial and temporal heterogeneity of mouse and human microglia at single-cell resolution
- (2019) Takahiro Masuda et al. NATURE
- Microglial Function Is Distinct in Different Anatomical Locations during Retinal Homeostasis and Degeneration
- (2019) Emily G. O’Koren et al. IMMUNITY
- Microglia monitor and protect neuronal function through specialized somatic purinergic junctions
- (2019) Csaba Cserép et al. SCIENCE
- Aging alters the immunological response to ischemic stroke
- (2018) Rodney M. Ritzel et al. ACTA NEUROPATHOLOGICA
- Impact of estrogens and estrogen receptor-α in brain lipid metabolism
- (2018) Eugenia Morselli et al. AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM
- Disease-Associated Microglia: A Universal Immune Sensor of Neurodegeneration
- (2018) Aleksandra Deczkowska et al. CELL
- Repopulated microglia are solely derived from the proliferation of residual microglia after acute depletion
- (2018) Yubin Huang et al. NATURE NEUROSCIENCE
- Lipid droplet density alters the early innate immune response to viral infection
- (2018) Ebony A. Monson et al. PLoS One
- Defective cholesterol clearance limits remyelination in the aged central nervous system
- (2018) Ludovico Cantuti-Castelvetri et al. SCIENCE
- Lipid droplet formation in Mycobacterium tuberculosis infected macrophages requires IFN-γ/HIF-1α signaling and supports host defense
- (2018) Matthew Knight et al. PLoS Pathogens
- Microglial cell loss after ischemic stroke favors brain neutrophil accumulation
- (2018) Amaia Otxoa-de-Amezaga et al. ACTA NEUROPATHOLOGICA
- Replacement of microglia in the aged brain reverses cognitive, synaptic, and neuronal deficits in mice
- (2018) Monica R. P. Elmore et al. AGING CELL
- Enforced microglial depletion and repopulation as a promising strategy for the treatment of neurological disorders
- (2018) Jinming Han et al. GLIA
- Single-Cell RNA Sequencing of Microglia throughout the Mouse Lifespan and in the Injured Brain Reveals Complex Cell-State Changes
- (2018) Timothy R. Hammond et al. IMMUNITY
- Developmental Heterogeneity of Microglia and Brain Myeloid Cells Revealed by Deep Single-Cell RNA Sequencing
- (2018) Qingyun Li et al. NEURON
- GENCODE reference annotation for the human and mouse genomes
- (2018) Adam Frankish et al. NUCLEIC ACIDS RESEARCH
- Forced turnover of aged microglia induces an intermediate phenotype but does not rebalance CNS environmental cues driving priming to immune challenge
- (2018) Shane M. O’Neil et al. Acta Neuropathologica Communications
- The Lifespan and Turnover of Microglia in the Human Brain
- (2017) Pedro Réu et al. Cell Reports
- Age-related myelin degradation burdens the clearance function of microglia during aging
- (2016) Shima Safaiyan et al. NATURE NEUROSCIENCE
- Microglia protect against brain injury and their selective elimination dysregulates neuronal network activity after stroke
- (2016) Gergely Szalay et al. Nature Communications
- Microglial priming and enhanced reactivity to secondary insult in aging, and traumatic CNS injury, and neurodegenerative disease
- (2015) Diana M. Norden et al. NEUROPHARMACOLOGY
- limma powers differential expression analyses for RNA-sequencing and microarray studies
- (2015) Matthew E. Ritchie et al. NUCLEIC ACIDS RESEARCH
- Homeostasis of Microglia in the Adult Brain: Review of Novel Microglia Depletion Systems
- (2015) Ari Waisman et al. TRENDS IN IMMUNOLOGY
- Microglia: Dynamic Mediators of Synapse Development and Plasticity
- (2015) Yuwen Wu et al. TRENDS IN IMMUNOLOGY
- Intranasal Insulin and Insulin-Like Growth Factor 1 as Neuroprotectants in Acute Ischemic Stroke
- (2015) Vasileios-Arsenios Lioutas et al. Translational Stroke Research
- Skewer: a fast and accurate adapter trimmer for next-generation sequencing paired-end reads
- (2014) Hongshan Jiang et al. BMC BIOINFORMATICS
- voom: precision weights unlock linear model analysis tools for RNA-seq read counts
- (2014) Charity W Law et al. GENOME BIOLOGY
- Microglial pathology
- (2014) Wolfgang J Streit et al. Acta Neuropathologica Communications
- The microglial sensome revealed by direct RNA sequencing
- (2013) Suzanne E Hickman et al. NATURE NEUROSCIENCE
- Targeting Mannose-Binding Lectin Confers Long-Lasting Protection With a Surprisingly Wide Therapeutic Window in Cerebral Ischemia
- (2012) Franca Orsini et al. CIRCULATION
- A Lineage of Myeloid Cells Independent of Myb and Hematopoietic Stem Cells
- (2012) C. Schulz et al. SCIENCE
- The Effects of Estrogen in Ischemic Stroke
- (2012) Edward C. Koellhoffer et al. Translational Stroke Research
- Peroxisomal alterations in Alzheimer’s disease
- (2011) Jianqiu Kou et al. ACTA NEUROPATHOLOGICA
- RSEM: accurate transcript quantification from RNA-Seq data with or without a reference genome
- (2011) Bo Li et al. BMC BIOINFORMATICS
- Antiviral Protein Viperin Promotes Toll-like Receptor 7- and Toll-like Receptor 9-Mediated Type I Interferon Production in Plasmacytoid Dendritic Cells
- (2011) Tatsuya Saitoh et al. IMMUNITY
- Ischemic stroke in the elderly: an overview of evidence
- (2010) Ruo-Li Chen et al. Nature Reviews Neurology
- Fate Mapping Analysis Reveals That Adult Microglia Derive from Primitive Macrophages
- (2010) F. Ginhoux et al. SCIENCE
- Influence of Age on Outcome From Thrombolysis in Acute Stroke
- (2010) Nishant Kumar Mishra et al. STROKE
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExploreAdd your recorded webinar
Do you already have a recorded webinar? Grow your audience and get more views by easily listing your recording on Peeref.
Upload Now