Stochastic phenotypes in RAS-dependent developmental diseases

Molecular mechanisms underlying cellular effects of human MEK1 mutations

(2021) Robert A. Marmion et al.   MOLECULAR BIOLOGY OF THE CELL

State-of-the-art CRISPR for in vivo and cell-based studies in Drosophila

(2021) Jonathan Zirin et al.   TRENDS IN GENETICS

Inference of Multisite Phosphorylation Rate Constants and Their Modulation by Pathogenic Mutations

(2020) Eyan Yeung et al.   CURRENT BIOLOGY

RASopathies

(2020) Mustufa Jafry et al.   CLINICS IN DERMATOLOGY

Rapid Dynamics of Signal-Dependent Transcriptional Repression by Capicua

(2020) Shannon E. Keenan et al.   DEVELOPMENTAL CELL

ERK signalling: a master regulator of cell behaviour, life and fate

(2020) Hugo Lavoie et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

The ETS-transcription factor Pointed is sufficient to regulate the posterior fate of the follicular epithelium

(2020) Cody A. Stevens et al.   DEVELOPMENT

A genotype-first approach to exploring Mendelian cardiovascular traits with clear external manifestations

(2020) Brittany M. Wenger et al.   GENETICS IN MEDICINE

RAS signalling in energy metabolism and rare human diseases

(2018) L. Dard et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

An inherited FGFR2 mutation increased osteogenesis gene expression and result in Crouzon syndrome

(2018) Jiayan Fan et al.   BMC Medical Genetics

Selfish mutations dysregulating RAS-MAPK signaling are pervasive in aged human testes

(2018) Geoffrey J. Maher et al.   GENOME RESEARCH

How activating mutations affect MEK1 regulation and function

(2017) Granton A. Jindal et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Divergent effects of intrinsically active MEK variants on developmental Ras signaling

(2017) Yogesh Goyal et al.   NATURE GENETICS

In vivo severity ranking of Ras pathway mutations associated with developmental disorders

(2017) Granton A. Jindal et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

OASIS 2: online application for survival analysis 2 with features for the analysis of maximal lifespan and healthspan in aging research

(2016) Seong Kyu Han et al.   Oncotarget

Quantitative Assessment of Eye Phenotypes for Functional Genetic Studies Using Drosophila melanogaster

(2016) Janani Iyer et al.   G3-Genes Genomes Genetics

Dynamics of Inductive ERK Signaling in the Drosophila Embryo

(2015) Bomyi Lim et al.   CURRENT BIOLOGY

Highly Specific and Efficient CRISPR/Cas9-Catalyzed Homology-Directed Repair inDrosophila

(2014) Scott J. Gratz et al.   GENETICS

The RASopathies

(2013) Katherine A. Rauen   Annual Review of Genomics and Human Genetics

ERK as a Model for Systems Biology of Enzyme Kinetics in Cells

(2013) Alan S. Futran et al.   CURRENT BIOLOGY

Genome Engineering of Drosophila with the CRISPR RNA-Guided Cas9 Nuclease

(2013) Scott J. Gratz et al.   GENETICS

Fiji: an open-source platform for biological-image analysis

(2012) Johannes Schindelin et al.   NATURE METHODS

Transcriptional interpretation of the EGF receptor signaling gradient

(2012) A. Fuchs et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Variable expression of neurofibromatosis 1 in monozygotic twins

(2011) Margaret B. Rieley et al.   AMERICAN JOURNAL OF MEDICAL GENETICS PART A

Monozygotic twins discordant for neurofibromatosis 1

(2010) Lee Kaplan et al.   AMERICAN JOURNAL OF MEDICAL GENETICS PART A

The Phosphatase SHP2 Regulates the Spacing Effect for Long-Term Memory Induction

(2009) Mario R. Pagani et al.   CELL

Feedback control of the EGFR signaling gradient: superposition of domain-splitting events in Drosophila oogenesis

(2009) J. J. Zartman et al.   DEVELOPMENT

Phosphatase-defective LEOPARD syndrome mutations in PTPN11 gene have gain-of-function effects during Drosophila development

(2008) Kimihiko Oishi et al.   HUMAN MOLECULAR GENETICS

Rapid identification of somatic mutations in colorectal and breast cancer tissues using mismatch repair detection (MRD)

(2008) Steven Bentivegna et al.   HUMAN MUTATION