Divergent effects of intrinsically active MEK variants on developmental Ras signaling

Layer specific and general requirements for ERK/MAPK signaling in the developing neocortex

(2016) Lei Xing et al.   eLife

A germlineMTORmutation in Aboriginal Australian siblings with intellectual disability, dysmorphism, macrocephaly, and small thoraces

(2015) Gareth Baynam et al.   AMERICAN JOURNAL OF MEDICAL GENETICS PART A

Dynamics of Inductive ERK Signaling in the Drosophila Embryo

(2015) Bomyi Lim et al.   CURRENT BIOLOGY

RASopathies: unraveling mechanisms with animal models

(2015) G. A. Jindal et al.   Disease Models & Mechanisms

Truncating mutations in the last exon ofNOTCH3cause lateral meningocele syndrome

(2014) Karen W. Gripp et al.   AMERICAN JOURNAL OF MEDICAL GENETICS PART A

Noonan and LEOPARD syndrome Shp2 variants induce heart displacement defects in zebrafish

(2014) Monica Bonetti et al.   DEVELOPMENT

PKA catalytic subunit mutations in adrenocortical Cushing’s adenoma impair association with the regulatory subunit

(2014) Davide Calebiro et al.   Nature Communications

The RASopathies

(2013) Katherine A. Rauen   Annual Review of Genomics and Human Genetics

Context-dependent transcriptional interpretation of mitogen activated protein kinase signaling in the Drosophila embryo

(2013) Yoosik Kim et al.   CHAOS

ERK-Mediated Phosphorylation of Fibroblast Growth Factor Receptor 1 on Ser777 Inhibits Signaling

(2013) M. Zakrzewska et al.   Science Signaling

Modulation of gurken translation by insulin and TOR signaling in Drosophila

(2012) S. B. Ferguson et al.   JOURNAL OF CELL SCIENCE

Exome sequencing identifies recurrent somatic MAP2K1 and MAP2K2 mutations in melanoma

(2011) Sergey I Nikolaev et al.   NATURE GENETICS

Analysis of a gain-of-function FGFR2 Crouzon mutation provides evidence of loss of function activity in the etiology of cleft palate

(2010) A. K. Snyder-Warwick et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Mammalian MAPK/ERK Pathway Exhibits Properties of a Negative Feedback Amplifier

(2010) O. E. Sturm et al.   Science Signaling

A functional antagonism between the pgc germline repressor and torso in the development of somatic cells

(2009) José Manuel de las Heras et al.   EMBO REPORTS

Impact of Feedback Phosphorylation and Raf Heterodimerization on Normal and Mutant B-Raf Signaling

(2009) D. A. Ritt et al.   MOLECULAR AND CELLULAR BIOLOGY

FGF signalling during embryo development regulates cilia length in diverse epithelia

(2009) Judith M. Neugebauer et al.   NATURE

Signaling dynamics of the KSR1 scaffold complex

(2009) M. M. McKay et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Endogenous expression of HrasG12V induces developmental defects and neoplasms with copy number imbalances of the oncogene

(2009) X. Chen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Insect Neuropeptide PTTH Activates Receptor Tyrosine Kinase Torso to Initiate Metamorphosis

(2009) K. F. Rewitz et al.   SCIENCE

Nuclear Trapping Shapes the Terminal Gradient in the Drosophila Embryo

(2008) Mathieu Coppey et al.   CURRENT BIOLOGY

Distinct functions for ERK1 and ERK2 in cell migration processes during zebrafish gastrulation

(2008) S.F. Gabby Krens et al.   DEVELOPMENTAL BIOLOGY