Cancer cells co-opt nociceptive nerves to thrive in nutrient-poor environments and upon nutrient-starvation therapies

The hallmarks of cancer metabolism: Still emerging

(2022) Natalya N. Pavlova et al.   Cell Metabolism

Single-cell landscapes of primary glioblastomas and matched explants and cell lines show variable retention of inter- and intratumor heterogeneity

(2022) Véronique G. LeBlanc et al.   CANCER CELL

Glutaminase inhibition impairs CD8 T cell activation in STK11-/Lkb1-deficient lung cancer

(2022) Sarah A. Best et al.   Cell Metabolism

Spatial and Transcriptomic Analysis of Perineural Invasion in Oral Cancer

(2022) Ligia B. Schmitd et al.   CLINICAL CANCER RESEARCH

Recent progress on vascular endothelial growth factor receptor inhibitors with dual targeting capabilities for tumor therapy

(2022) Yun Liu et al.   Journal of Hematology & Oncology

Angiogenesis Inhibitors for Head and Neck Squamous Cell Carcinoma Treatment: Is There Still Hope?

(2021) Aini Hyytiäinen et al.   Frontiers in Oncology

Fasting-mimicking diet blocks triple-negative breast cancer and cancer stem cell escape

(2021) Giulia Salvadori et al.   Cell Metabolism

Dietary palmitic acid promotes a prometastatic memory via Schwann cells

(2021) Gloria Pascual et al.   NATURE

Targeting cancer metabolism in the era of precision oncology

(2021) Zachary E. Stine et al.   NATURE REVIEWS DRUG DISCOVERY

JASPAR 2022: the 9th release of the open-access database of transcription factor binding profiles

(2021) Jaime A Castro-Mondragon et al.   NUCLEIC ACIDS RESEARCH

Loss of p53 drives neuron reprogramming in head and neck cancer

(2020) Moran Amit et al.   NATURE

mTOR at the nexus of nutrition, growth, ageing and disease

(2020) Grace Y. Liu et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Roadmap for the Emerging Field of Cancer Neuroscience

(2020) Michelle Monje et al.   CELL

Neuro-immune Interactions in the Tissues

(2020) Coco Chu et al.   IMMUNITY

The Neuropeptide System and Colorectal Cancer Liver Metastases: Mechanisms and Management

(2020) Aldona Kasprzak et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Rap1-GTPases control mTORC1 activity by coordinating lysosome organization with amino acid availability

(2020) Anders P. Mutvei et al.   Nature Communications

Regeneration of adult rat sensory and motor neuron axons through chimeric peroneal nerve grafts containing donor Schwann cells engineered to express different neurotrophic factors

(2020) Maria João Godinho et al.   EXPERIMENTAL NEUROLOGY

Metabolic regulation in HPV associated head and neck squamous cell carcinoma

(2020) Vaishali Chandel et al.   LIFE SCIENCES

Cancer SLC43A2 alters T cell methionine metabolism and histone methylation

(2020) Yingjie Bian et al.   NATURE

Cancer-associated neurogenesis and nerve-cancer crosstalk

(2020) Deborah A Silverman et al.   CANCER RESEARCH

Lymph nodes are innervated by a unique population of sensory neurons with immunomodulatory potential

(2020) Siyi Huang et al.   CELL

Nociceptive nerves regulate haematopoietic stem cell mobilization

(2020) Xin Gao et al.   NATURE

Melanoma-induced reprogramming of Schwann cell signaling aids tumor growth

(2019) Galina V. Shurin et al.   CANCER RESEARCH

Progenitors from the central nervous system drive neurogenesis in cancer

(2019) Philippe Mauffrey et al.   NATURE

Genetic manipulation of autonomic nerve fiber innervation and activity and its effect on breast cancer progression

(2019) Atsunori Kamiya et al.   NATURE NEUROSCIENCE

Rimegepant, an Oral Calcitonin Gene–Related Peptide Receptor Antagonist, for Migraine

(2019) Richard B. Lipton et al.   NEW ENGLAND JOURNAL OF MEDICINE

Electrical and synaptic integration of glioma into neural circuits

(2019) Humsa S. Venkatesh et al.   NATURE

Glutamatergic synaptic input to glioma cells drives brain tumour progression

(2019) Varun Venkataramani et al.   NATURE

The dichotomous role of the glycolytic metabolism pathway in cancer metastasis: Interplay with the complex tumor microenvironment and novel therapeutic strategies

(2019) Btissame El Hassouni et al.   SEMINARS IN CANCER BIOLOGY

Phase III Randomized Trial of Chemotherapy With or Without Bevacizumab in Patients With Recurrent or Metastatic Head and Neck Cancer

(2019) Athanassios Argiris et al.   JOURNAL OF CLINICAL ONCOLOGY

Gut-Innervating Nociceptor Neurons Regulate Peyer’s Patch Microfold Cells and SFB Levels to Mediate Salmonella Host Defense

(2019) Nicole Y. Lai et al.   CELL

Blood Pressure Normalization–Independent Cardioprotective Effects of Endogenous, Physical Activity–Induced αCGRP (α Calcitonin Gene-Related Peptide) in Chronically Hypertensive Mice

(2019) Tom Skaria et al.   CIRCULATION RESEARCH

Targeting glucose metabolism to suppress cancer progression: prospective of anti-glycolytic cancer therapy

(2019) Ali F. Abdel-Wahab et al.   PHARMACOLOGICAL RESEARCH

Syngeneic animal models of tobacco-associated oral cancer reveal the activity of in situ anti-CTLA-4

(2019) Zhiyong Wang et al.   Nature Communications

Blocking Neuronal Signaling to Immune Cells Treats Streptococcal Invasive Infection

(2018) Felipe A. Pinho-Ribeiro et al.   CELL

Pharmacological blockade of ASCT2-dependent glutamine transport leads to antitumor efficacy in preclinical models

(2018) Michael L Schulte et al.   NATURE MEDICINE

Metabolic signature of squamous cell carcinoma of the head and neck: Consequences of TP53 mutation and therapeutic perspectives

(2018) Mark D. Wilkie et al.   ORAL ONCOLOGY

Ras and Rap1: A tale of two GTPases

(2018) Seema Shah et al.   SEMINARS IN CANCER BIOLOGY

Molecular Architecture of the Mouse Nervous System

(2018) Amit Zeisel et al.   CELL

AnimalTFDB 3.0: a comprehensive resource for annotation and prediction of animal transcription factors

(2018) Hui Hu et al.   NUCLEIC ACIDS RESEARCH

Effect of Anlotinib as a Third-Line or Further Treatment on Overall Survival of Patients With Advanced Non–Small Cell Lung Cancer

(2018) Baohui Han et al.   JAMA Oncology

GEPIA: a web server for cancer and normal gene expression profiling and interactive analyses

(2017) Zefang Tang et al.   NUCLEIC ACIDS RESEARCH

Adrenergic nerves activate an angio-metabolic switch in prostate cancer

(2017) Ali H. Zahalka et al.   SCIENCE

The Emerging Hallmarks of Cancer Metabolism

(2016) Natalya N. Pavlova et al.   Cell Metabolism

Adeno-associated Virus Vectors Efficiently Transduce Mouse and Rabbit Sensory Neurons Coinfected with Herpes Simplex Virus 1 following Peripheral Inoculation

(2016) Zachary L. Watson et al.   JOURNAL OF VIROLOGY

Implant-derived magnesium induces local neuronal production of CGRP to improve bone-fracture healing in rats

(2016) Yifeng Zhang et al.   NATURE MEDICINE

A Designer AAV Variant Permits Efficient Retrograde Access to Projection Neurons

(2016) D. Gowanlock R. Tervo et al.   NEURON

Ablation of sensory neurons in a genetic model of pancreatic ductal adenocarcinoma slows initiation and progression of cancer

(2016) Jami L. Saloman et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Metabolomics of Head and Neck Cancer: A Mini-Review

(2016) Jae M. Shin et al.   Frontiers in Physiology

A novel analgesic approach to optogenetically and specifically inhibit pain transmission using TRPV1 promoter

(2015) Bei Li et al.   BRAIN RESEARCH

Neuronal Activity Promotes Glioma Growth through Neuroligin-3 Secretion

(2015) Humsa S. Venkatesh et al.   CELL

Basal Cell Carcinoma Preferentially Arises from Stem Cells within Hair Follicle and Mechanosensory Niches

(2015) Shelby C. Peterson et al.   Cell Stem Cell

Neuropeptide Y stimulates autophagy in hypothalamic neurons

(2015) Célia A. Aveleira et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Hypoglycemia-Activated GLUT2 Neurons of the Nucleus Tractus Solitarius Stimulate Vagal Activity and Glucagon Secretion

(2014) Christophe M. Lamy et al.   Cell Metabolism

Calcitonin Gene-Related Peptide: Physiology and Pathophysiology

(2014) F. A. Russell et al.   PHYSIOLOGICAL REVIEWS

Glucose and glutamine metabolism in oral squamous cell carcinoma: insight from a quantitative metabolomic approach

(2014) Tamaki Ogawa et al.   Oral Surgery Oral Medicine Oral Pathology Oral Radiology

GSVA: gene set variation analysis for microarray and RNA-Seq data

(2013) Sonja Hänzelmann et al.   BMC BIOINFORMATICS

Profiling of Glucose-Sensing Neurons Reveals that GHRH Neurons Are Activated by Hypoglycemia

(2013) Sarah Stanley et al.   Cell Metabolism

Sustained Correction of Motoneuron Histopathology Following Intramuscular Delivery of AAV in Pompe Mice

(2013) Mai K ElMallah et al.   MOLECULAR THERAPY

Defective glucose metabolism in polycystic kidney disease identifies a new therapeutic strategy

(2013) Isaline Rowe et al.   NATURE MEDICINE

Autonomic Nerve Development Contributes to Prostate Cancer Progression

(2013) C. Magnon et al.   SCIENCE

Antiangiogenic therapy—evolving view based on clinical trial results

(2012) Gordon C. Jayson et al.   Nature Reviews Clinical Oncology

TRPV1 activation improves exercise endurance and energy metabolism through PGC-1α upregulation in mice

(2011) Zhidan Luo et al.   CELL RESEARCH

Altered metabolism in head and neck squamous cell carcinoma: an opportunity for identification of novel biomarkers and drug targets

(2011) Vlad C. Sandulache et al.   HEAD AND NECK-JOURNAL FOR THE SCIENCES AND SPECIALTIES OF THE HEAD AND NECK

Perineural invasion in oral squamous cell carcinoma: A discussion of significance and review of the literature

(2011) Nada O. Binmadi et al.   ORAL ONCOLOGY

Primary oral melanoma: A histopathological and immunohistochemical study of 22 cases of Latin America

(2011) BAB. de-Andrade et al.   Medicina Oral Patologia Oral y Cirugia Bucal

Comparative Study of the Gating Motif and C-type Inactivation in Prokaryotic Voltage-gated Sodium Channels

(2009) Katsumasa Irie et al.   JOURNAL OF BIOLOGICAL CHEMISTRY