Hydroxycarboxylic acid receptor 2 mediates dimethyl fumarate’s protective effect in EAE

Dimethyl fumarate: a Janus-faced substance?

(2013) Frieder Kees   EXPERT OPINION ON PHARMACOTHERAPY

Myelin Repair Is Accelerated by Inactivating CXCR2 on Nonhematopoietic Cells

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(2012) Richard M. Ransohoff et al.   JOURNAL OF CLINICAL INVESTIGATION

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(2012) Robert J. Fox et al.   NEW ENGLAND JOURNAL OF MEDICINE

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(2012) Ralf Gold et al.   NEW ENGLAND JOURNAL OF MEDICINE

Fumaric acid esters exert neuroprotective effects in neuroinflammation via activation of the Nrf2 antioxidant pathway

(2011) Ralf A. Linker et al.   BRAIN

Fumarates improve psoriasis and multiple sclerosis by inducing type II dendritic cells

(2011) Kamran Ghoreschi et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Neutrophils in multiple sclerosis are characterized by a primed phenotype

(2011) Matthias Naegele et al.   JOURNAL OF NEUROIMMUNOLOGY

International Union of Basic and Clinical Pharmacology. LXXXII: Nomenclature and Classification of Hydroxy-carboxylic Acid Receptors (GPR81, GPR109A, and GPR109B)

(2011) S. Offermanns et al.   PHARMACOLOGICAL REVIEWS

Nicotinic acid (niacin): new lipid-independent mechanisms of action and therapeutic potentials

(2011) Martina Lukasova et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

Mouse models for multiple sclerosis: Historical facts and future implications

(2010) Andrew L. Croxford et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Nicotinic acid– and monomethyl fumarate–induced flushing involves GPR109A expressed by keratinocytes and COX-2–dependent prostanoid formation in mice

(2010) Julien Hanson et al.   JOURNAL OF CLINICAL INVESTIGATION

Activation of cannabinoid 2 receptors protects against cerebral ischemia by inhibiting neutrophil recruitment

(2009) Sasidhar Murikinati et al.   FASEB JOURNAL

β-Arrestin1 mediates nicotinic acid–induced flushing, but not its antilipolytic effect, in mice

(2009) Robert W. Walters et al.   JOURNAL OF CLINICAL INVESTIGATION

The psoriasis drug monomethylfumarate is a potent nicotinic acid receptor agonist

(2008) Hua Tang et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

The Th17–ELR+CXC chemokine pathway is essential for the development of central nervous system autoimmune disease

(2008) Thaddeus Carlson et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Niaspan treatment improves neurological functional recovery in experimental autoimmune encephalomyelitis mice

(2008) Jing Zhang et al.   NEUROBIOLOGY OF DISEASE