Pomalidomide mitigates neuronal loss, neuroinflammation, and behavioral impairments induced by traumatic brain injury in rat
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Title
Pomalidomide mitigates neuronal loss, neuroinflammation, and behavioral impairments induced by traumatic brain injury in rat
Authors
Keywords
Pomalidomide, Thalidomide, Traumatic brain injury, Controlled cortical impact, Tumor necrosis factor-α, Interleukin-1β, Interleukin-6, Glutamate excitotoxicity, Neuronal apoptosis, Neuroinflammation
Journal
Journal of Neuroinflammation
Volume 13, Issue 1, Pages -
Publisher
Springer Nature
Online
2016-06-29
DOI
10.1186/s12974-016-0631-6
References
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Note: Only part of the references are listed.- Neuroprotective Effects of Resatorvid Against Traumatic Brain Injury in Rat: Involvement of Neuronal Autophagy and TLR4 Signaling Pathway
- (2016) Yan Feng et al. CELLULAR AND MOLECULAR NEUROBIOLOGY
- Treatment of traumatic brain injury with anti-inflammatory drugs
- (2016) Peter J. Bergold EXPERIMENTAL NEUROLOGY
- Immunomodulatory drugs inhibit TLR4-induced type-1 interferon production independently of Cereblonviasuppression of the TRIF/IRF3 pathway
- (2016) David Millrine et al. INTERNATIONAL IMMUNOLOGY
- Depletion of the cereblon gene activates the unfolded protein response and protects cells from ER stress-induced cell death
- (2015) Kwang Min Lee et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Thalidomide-induced teratogenesis: History and mechanisms
- (2015) Neil Vargesson BIRTH DEFECTS RESEARCH PART C-EMBRYO TODAY-REVIEWS
- Post-trauma administration of the pifithrin-α oxygen analog improves histological and functional outcomes after experimental traumatic brain injury
- (2015) L.-Y. Yang et al. EXPERIMENTAL NEUROLOGY
- Transiently lowering tumor necrosis factor-α synthesis ameliorates neuronal cell loss and cognitive impairments induced by minimal traumatic brain injury in mice
- (2015) Renana Baratz et al. Journal of Neuroinflammation
- Epidemiology of mild traumatic brain injury and neurodegenerative disease
- (2015) Raquel C. Gardner et al. MOLECULAR AND CELLULAR NEUROSCIENCE
- The European Medicines Agency Review of Pomalidomide in Combination With Low-Dose Dexamethasone for the Treatment of Adult Patients With Multiple Myeloma: Summary of the Scientific Assessment of the Committee for Medicinal Products for Human Use
- (2015) Z. Hanaizi et al. ONCOLOGIST
- Incretin mimetics as pharmacologic tools to elucidate and as a new drug strategy to treat traumatic brain injury
- (2014) Nigel H. Greig et al. Alzheimers & Dementia
- In vivo murine model of acquired resistance in myeloma reveals differential mechanisms for lenalidomide and pomalidomide in combination with dexamethasone
- (2014) E M Ocio et al. LEUKEMIA
- Traumatic brain injury and risk of dementia in older veterans
- (2014) D. E. Barnes et al. NEUROLOGY
- Tumor Necrosis Factor in Traumatic Brain Injury: Effects of Genetic Deletion of p55 or p75 Receptor
- (2013) Luca Longhi et al. JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM
- 3,6′-dithiothalidomide improves experimental stroke outcome by suppressing neuroinflammation
- (2013) Jeong Seon Yoon et al. JOURNAL OF NEUROSCIENCE RESEARCH
- Temporal trends and volume-outcome associations after traumatic brain injury: a 12-year study in Taiwan
- (2013) Hon-Yi Shi et al. JOURNAL OF NEUROSURGERY
- Thalidomide-analogue biology: immunological, molecular and epigenetic targets in cancer therapy
- (2013) J Shortt et al. ONCOGENE
- Pomalidomide Shows Significant Therapeutic Activity against CNS Lymphoma with a Major Impact on the Tumor Microenvironment in Murine Models
- (2013) Zhimin Li et al. PLoS One
- Pomalidomide is nonteratogenic in chicken and zebrafish embryos and nonneurotoxic in vitro
- (2013) C. Mahony et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Pomalidomide: the new immunomodulatory agent for the treatment of multiple myeloma
- (2013) A A Chanan-Khan et al. Blood Cancer Journal
- Pomalidomide is effective for prevention and treatment of experimental skin fibrosis
- (2012) Simon Weingärtner et al. ANNALS OF THE RHEUMATIC DISEASES
- Bone marrow derived mesenchymal stem cells from aged mice have reduced wound healing, angiogenesis, proliferation and anti-apoptosis capabilities
- (2012) Mahmood Saba Choudhery et al. CELL BIOLOGY INTERNATIONAL
- Effective Treatment of Traumatic Brain Injury
- (2012) Robert L. Ruff et al. JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION
- Early intervention with a small molecule inhibitor for tumor nefosis factor-α prevents cognitive deficits in a triple transgenic mouse model of Alzheimer’s disease
- (2012) S Prasad Gabbita et al. Journal of Neuroinflammation
- Tumor necrosis factor-α synthesis inhibitor 3,6′-dithiothalidomide attenuates markers of inflammation, Alzheimer pathology and behavioral deficits in animal models of neuroinflammation and Alzheimer’s disease
- (2012) David Tweedie et al. Journal of Neuroinflammation
- Cereblon is a direct protein target for immunomodulatory and antiproliferative activities of lenalidomide and pomalidomide
- (2012) A Lopez-Girona et al. LEUKEMIA
- Molecular mechanism of action of immune-modulatory drugs thalidomide, lenalidomide and pomalidomide in multiple myeloma
- (2012) Yuan Xiao Zhu et al. LEUKEMIA & LYMPHOMA
- Targeting TNF-Alpha to Elucidate and Ameliorate Neuroinflammation in Neurodegenerative Diseases
- (2011) Kathryn A. Frankola et al. CNS & Neurological Disorders-Drug Targets
- Repeat traumatic brain injury in the developing brain
- (2011) M.L. Prins et al. INTERNATIONAL JOURNAL OF DEVELOPMENTAL NEUROSCIENCE
- Tumor necrosis factor-α synthesis inhibitor, 3,6′-dithiothalidomide, reverses behavioral impairments induced by minimal traumatic brain injury in mice
- (2011) Renana Baratz et al. JOURNAL OF NEUROCHEMISTRY
- Pharmacological inhibition of lipid peroxidation attenuates calpain-mediated cytoskeletal degradation after traumatic brain injury
- (2011) Ayman G. Mustafa et al. JOURNAL OF NEUROCHEMISTRY
- mRNA distribution of the thalidomide binding protein cereblon in adult mouse brain
- (2011) Miho Aizawa et al. NEUROSCIENCE RESEARCH
- The Molecular Pathophysiology of Concussive Brain Injury
- (2010) Garni Barkhoudarian et al. CLINICS IN SPORTS MEDICINE
- Identification of a Primary Target of Thalidomide Teratogenicity
- (2010) T. Ito et al. SCIENCE
- Inhibition of metastatic potential in colorectal carcinoma in vivo and in vitro using immunomodulatory drugs (IMiDs)
- (2009) W M Liu et al. BRITISH JOURNAL OF CANCER
- In Situ Detection of Inflammatory Mediators in Post Mortem Human Brain Tissue after Traumatic Injury
- (2009) Tony Frugier et al. JOURNAL OF NEUROTRAUMA
- Pathophysiology of traumatic brain injury
- (2009) Mark W. Greve et al. MOUNT SINAI JOURNAL OF MEDICINE
- The adhesive removal test: a sensitive method to assess sensorimotor deficits in mice
- (2009) Valentine Bouet et al. Nature Protocols
- Methamphetamine induces heme oxygenase-1 expression in cortical neurons and glia to prevent its toxicity
- (2009) Ya-Ni Huang et al. TOXICOLOGY AND APPLIED PHARMACOLOGY
- Post-injury baicalein improves histological and functional outcomes and reduces inflammatory cytokines after experimental traumatic brain injury
- (2008) S-F Chen et al. BRITISH JOURNAL OF PHARMACOLOGY
- TNF signaling inhibition in the CNS: implications for normal brain function and neurodegenerative disease
- (2008) Melissa K McCoy et al. Journal of Neuroinflammation
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