Early intervention with a small molecule inhibitor for tumor nefosis factor-α prevents cognitive deficits in a triple transgenic mouse model of Alzheimer’s disease

CCR6: A Biomarker for Alzheimer's-like Disease in a Triple Transgenic Mouse Model

(2017) Sandhya Subramanian et al.   JOURNAL OF ALZHEIMERS DISEASE

Latency-Associated Peptide Identifies a Novel CD4+CD25+ Regulatory T Cell Subset with TGF -Mediated Function and Enhanced Suppression of Experimental Autoimmune Encephalomyelitis

(2014) M.-L. Chen et al.   JOURNAL OF IMMUNOLOGY

Proteomic Changes in Cerebrospinal Fluid of Presymptomatic and Affected Persons Carrying Familial Alzheimer Disease Mutations

(2012) John M. Ringman   ARCHIVES OF NEUROLOGY

Design, synthesis and biological assessment of novel N-substituted 3-(phthalimidin-2-yl)-2,6-dioxopiperidines and 3-substituted 2,6-dioxopiperidines for TNF-α inhibitory activity

(2011) Weiming Luo et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Role of pro-inflammatory cytokines released from microglia in neurodegenerative diseases

(2011) Joshua A. Smith et al.   BRAIN RESEARCH BULLETIN

Tumor necrosis factor-α synthesis inhibitor, 3,6′-dithiothalidomide, reverses behavioral impairments induced by minimal traumatic brain injury in mice

(2011) Renana Baratz et al.   JOURNAL OF NEUROCHEMISTRY

Tumor Necrosis Factor-alpha and the Roles it Plays in Homeostatic and Degenerative Processes Within the Central Nervous System

(2011) Sara L. Montgomery et al.   Journal of Neuroimmune Pharmacology

TNF-α Contributes to Caspase-3 Independent Apoptosis in Neuroblastoma Cells: Role of NFAT

(2011) Susana Álvarez et al.   PLoS One

Anti-TNF-α reduces amyloid plaques and tau phosphorylation and induces CD11c-positive dendritic-like cell in the APP/PS1 transgenic mouse brains

(2010) Jian-Quan Shi et al.   BRAIN RESEARCH

Tumor Necrosis Factor-  Signaling Maintains the Ability of Cortical Synapses to Express Synaptic Scaling

(2010) C. C. Steinmetz et al.   JOURNAL OF NEUROSCIENCE

Decreased behavioral impairments in an Alzheimer mice model by interfering with TNF-alpha metabolism

(2009) Fabienne Giuliani et al.   BRAIN RESEARCH BULLETIN

Amyloid Deposition and Inflammation in APPswe/PS1dE9 Mouse Model of Alzheimers Disease

(2009) Lingfei Ruan et al.   Current Alzheimer Research

Tumor necrosis factor-α-induced neutral sphingomyelinase-2 modulates synaptic plasticity by controlling the membrane insertion of NMDA receptors

(2009) David Wheeler et al.   JOURNAL OF NEUROCHEMISTRY

Tumour necrosis factor-α impairs neuronal differentiation but not proliferation of hippocampal neural precursor cells: Role of Hes1

(2009) Aoife Keohane et al.   MOLECULAR AND CELLULAR NEUROSCIENCE

Rapid improvement in verbal fluency and aphasia following perispinal etanercept in Alzheimer's disease

(2008) Edward L Tobinick et al.   BMC Neurology

The Blood-Central Nervous System Barriers Actively Control Immune Cell Entry into the Central Nervous System

(2008) Britta Engelhardt   CURRENT PHARMACEUTICAL DESIGN

Minocycline reduces engraftment and activation of bone marrow-derived cells but sustains their phagocytic activity in a mouse model of Alzheimer's disease

(2008) Tarja M. Malm et al.   GLIA

Tumor Necrosis Factor-α Potentiates Intraneuronal Ca2+Signaling via Regulation of the Inositol 1,4,5-Trisphosphate Receptor

(2008) Keigan M. Park et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Rapid cognitive improvement in Alzheimer's disease following perispinal etanercept administration

(2008) Edward L Tobinick et al.   Journal of Neuroinflammation

Tumor Necrosis Factor-α Modulates Survival, Proliferation, and Neuronal Differentiation in Neonatal Subventricular Zone Cell Cultures

(2008) Liliana Bernardino et al.   STEM CELLS

Restraining tumor necrosis factor-alpha by thalidomide prevents the Amyloid beta-induced impairment of recognition memory in mice

(2007) Tursun Alkam et al.   BEHAVIOURAL BRAIN RESEARCH